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Aliases for HSBP1L1 Gene

Aliases for HSBP1L1 Gene

  • Heat Shock Factor Binding Protein 1-Like 1 2 3 5

External Ids for HSBP1L1 Gene

Previous GeneCards Identifiers for HSBP1L1 Gene

  • GC18P077724
  • GC18P074346

Summaries for HSBP1L1 Gene

GeneCards Summary for HSBP1L1 Gene

HSBP1L1 (Heat Shock Factor Binding Protein 1-Like 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HSBP1L1 Gene

Genomics for HSBP1L1 Gene

Regulatory Elements for HSBP1L1 Gene

Enhancers for HSBP1L1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around HSBP1L1 on UCSC Golden Path with GeneCards custom track

Promoters for HSBP1L1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around HSBP1L1 on UCSC Golden Path with GeneCards custom track

Genomic Location for HSBP1L1 Gene

79,964,561 bp from pter
79,970,822 bp from pter
6,262 bases
Plus strand

Genomic View for HSBP1L1 Gene

Genes around HSBP1L1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HSBP1L1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HSBP1L1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HSBP1L1 Gene

Proteins for HSBP1L1 Gene

  • Protein details for HSBP1L1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Heat shock factor-binding protein 1-like protein 1
    Protein Accession:
    Secondary Accessions:
    • B2RXG9

    Protein attributes for HSBP1L1 Gene

    74 amino acids
    Molecular mass:
    8384 Da
    Quaternary structure:
    No Data Available

neXtProt entry for HSBP1L1 Gene

Proteomics data for HSBP1L1 Gene at MOPED

Post-translational modifications for HSBP1L1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for HSBP1L1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for HSBP1L1 Gene

Domains & Families for HSBP1L1 Gene

Protein Domains for HSBP1L1 Gene


Suggested Antigen Peptide Sequences for HSBP1L1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the HSBP1 family.
  • Belongs to the HSBP1 family.
genes like me logo Genes that share domains with HSBP1L1: view

No data available for Gene Families for HSBP1L1 Gene

Function for HSBP1L1 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for HSBP1L1 Gene

Localization for HSBP1L1 Gene

Subcellular locations from

Jensen Localization Image for HSBP1L1 Gene COMPARTMENTS Subcellular localization image for HSBP1L1 gene
Compartment Confidence
nucleus 3
extracellular 2
cytosol 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for HSBP1L1 Gene

Pathways & Interactions for HSBP1L1 Gene

SuperPathways for HSBP1L1 Gene

No Data Available

Interacting Proteins for HSBP1L1 Gene

Selected Interacting proteins: C9JCN9-HSBPL_HUMAN for HSBP1L1 Gene via I2D

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for HSBP1L1 Gene


No data available for Pathways by source and SIGNOR curated interactions for HSBP1L1 Gene

Drugs & Compounds for HSBP1L1 Gene

No Compound Related Data Available

Transcripts for HSBP1L1 Gene

mRNA/cDNA for HSBP1L1 Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HSBP1L1 Gene

Heat shock factor binding protein 1-like 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for HSBP1L1 Gene

No ASD Table

Relevant External Links for HSBP1L1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for HSBP1L1 Gene

mRNA expression in normal human tissues for HSBP1L1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for HSBP1L1 Gene

This gene is overexpressed in Cerebrospinal fluid (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for HSBP1L1 Gene

SOURCE GeneReport for Unigene cluster for HSBP1L1 Gene Hs.191582

genes like me logo Genes that share expression patterns with HSBP1L1: view

Protein tissue co-expression partners for HSBP1L1 Gene

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for HSBP1L1 Gene

Orthologs for HSBP1L1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for HSBP1L1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia HSBP1L1 35
  • 84.02 (n)
  • 79.45 (a)
(Canis familiaris)
Mammalia HSBP1L1 35
  • 84.76 (n)
  • 81.43 (a)
HSBP1L1 36
  • 83 (a)
(Mus musculus)
Mammalia Hsbp1l1 35
  • 76.33 (n)
  • 75.36 (a)
Hsbp1l1 16
Hsbp1l1 36
  • 72 (a)
(Rattus norvegicus)
Mammalia Hsbp1l1 35
  • 82.13 (n)
  • 79.71 (a)
(Pan troglodytes)
Mammalia HSBP1L1 36
  • 84 (a)
(Gallus gallus)
Aves HSBP1L1 36
  • 51 (a)
Species with no ortholog for HSBP1L1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for HSBP1L1 Gene

Gene Tree for HSBP1L1 (if available)
Gene Tree for HSBP1L1 (if available)

Paralogs for HSBP1L1 Gene

(1) SIMAP similar genes for HSBP1L1 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with HSBP1L1: view

No data available for Paralogs for HSBP1L1 Gene

Variants for HSBP1L1 Gene

Sequence variations from dbSNP and Humsavar for HSBP1L1 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type
rs4799112 -- 79,967,126(+) CTGGG(C/T)GACAG intron-variant
rs4799113 -- 79,970,197(+) CTGCC(A/G)AATAT intron-variant
rs8085827 -- 79,962,617(+) TCCAC(A/G)CTGGC upstream-variant-2KB
rs5826683 -- 79,969,752(+) TGCCC(-/CTTG)CTTTT intron-variant
rs5826684 -- 79,969,755(+) CCCTT(-/GCTT)TTTTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for HSBP1L1 Gene

Variant ID Type Subtype PubMed ID
nsv428359 CNV Gain 18775914
nsv910009 CNV Loss 21882294
nsv470437 CNV Loss 18288195
nsv910039 CNV Loss 21882294
dgv3492n71 CNV Loss 21882294
nsv469607 CNV Loss 16826518
nsv910064 CNV Loss 21882294

Variation tolerance for HSBP1L1 Gene

Gene Damage Index Score: 0.20; 4.41% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for HSBP1L1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HSBP1L1 Gene

Disorders for HSBP1L1 Gene

Relevant External Links for HSBP1L1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for HSBP1L1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HSBP1L1 Gene

Publications for HSBP1L1 Gene

  1. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 67
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for HSBP1L1 Gene

Sources for HSBP1L1 Gene