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HSBP1 Gene

protein-coding   GIFtS: 50
GCID: GC16P083841

Heat Shock Factor Binding Protein 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Heat Shock Factor Binding Protein 11 2
Nasopharyngeal Carcinoma-Associated Antigen 132 3
NPC-A-132 3
Heat Shock Factor-Binding Protein 12
HSF1BP3

External Ids:    HGNC: 52031   Entrez Gene: 32812   Ensembl: ENSG000002309897   OMIM: 6045535   UniProtKB: O755063   

Export aliases for HSBP1 gene to outside databases

Previous GC identifers: GC16P074690 GC16P084806 GC16P083580 GC16P083621 GC16P082400 GC16P069593


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for HSBP1 Gene:
The heat-shock response is elicited by exposure of cells to thermal and chemical stress and through the activation
of HSFs (heat shock factors) results in the elevated expression of heat-shock induced genes. Heat shock factor
binding protein 1 (HSBP1), is a 76-amino-acid protein that binds to heat shock factor 1(HSF1), which is a
transcription factor involved in the HS response. During HS response, HSF1 undergoes conformational transition
from an inert non-DNA-binding monomer to active functional trimers. HSBP1 is nuclear-localized and interacts with
the active trimeric state of HSF1 to negatively regulate HSF1 DNA-binding activity. Overexpression of HSBP1 in
mammalian cells represses the transactivation activity of HSF1. When overexpressed in C.elegans HSBP1 has severe
effects on survival of the animals after thermal and chemical stress consistent with a role of HSBP1 as a
negative regulator of heat shock response. (provided by RefSeq, Jul 2008)

GeneCards Summary for HSBP1 Gene:
HSBP1 (heat shock factor binding protein 1) is a protein-coding gene. Diseases associated with HSBP1 include nasopharyngitis, and breast cancer. GO annotations related to this gene include transcription corepressor activity.

UniProtKB/Swiss-Prot: HSBP1_HUMAN, O75506
Function: Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a
role in the suppression of the activation of the stress response during the aging process




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000016.10  NC_018927.2  NT_010498.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the HSBP1 gene promoter:
         Bach1   p53   Pax-6   LCR-F1   GATA-1   AREB6   HSF2   COMP1   IRF-7A   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHSBP1 promoter sequence
   Search Chromatin IP Primers for HSBP1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HSBP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q23.3   Ensembl cytogenetic band:  16q23.3   HGNC cytogenetic band: 16q23.3

HSBP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HSBP1 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P083841:  view genomic region     (about GC identifiers)

Start:
83,841,448 bp from pter      End:
83,853,342 bp from pter
Size:
11,895 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: HSBP1_HUMAN, O75506 (See protein sequence)
Recommended Name: Heat shock factor-binding protein 1  
Size: 76 amino acids; 8544 Da
Subunit: Homohexamer. Associates with heptad repeats of HSF1 trimers and problaby also HSF1 monomers, and with
HSP70. Association with HSF1 trimers and HSP70 coincides with attenuation of heat shock response and the
conversion of HSF1 trimer to monomer
1 PDB 3D structure from and Proteopedia for HSBP1:
3CI9 (3D)    
Secondary accessions: Q53XA8 Q7Z5Z3

Explore the universe of human proteins at neXtProt for HSBP1: NX_O75506

Explore proteomics data for HSBP1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See HSBP1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001528.1  
    ENSEMBL proteins: 
     ENSP00000392896   ENSP00000458007   ENSP00000456049  
    Reactome Protein details: O75506

    HSBP1 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for HSBP1

    HSBP1 Antibody Products:

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    LSBio Antibodies in human, mouse, rat for HSBP1

    HSBP1 Assay Products:

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    Cloud-Clone Corp. ELISAs for HSBP1
    Cloud-Clone Corp. CLIAs for HSBP1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR009643 HS1-bd

    Graphical View of Domain Structure for InterPro Entry O75506

    ProtoNet protein and cluster: O75506

    UniProtKB/Swiss-Prot: HSBP1_HUMAN, O75506
    Similarity: Belongs to the HSBP1 family


    HSBP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HSBP1_HUMAN, O75506
    Function: Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a
    role in the suppression of the activation of the stress response during the aging process

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003714transcription corepressor activity TAS9649501
         
    HSBP1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HSBP1
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HSBP1
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    miRNA
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    Block miRNA regulation of human, mouse, rat HSBP1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HSBP1 (see all 32):
    hsa-miR-1271 hsa-miR-374a hsa-miR-449a hsa-miR-3167 hsa-miR-421 hsa-miR-1244 hsa-miR-649 hsa-miR-1323
    SwitchGear 3'UTR luciferase reporter plasmidHSBP1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for HSBP1
    Predesigned siRNA for gene silencing in human, mouse, rat HSBP1

    Gene Editing
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    Sino Biological Human cDNA Clone for HSBP1
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSBP1

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    HSBP1_HUMAN, O75506: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytoskeleton2
    cytosol2
    extracellular1
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005856cytoskeleton IEA--

    HSBP1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Pathways by sourceSee SuperPaths
    Show all pathways



    3 Reactome Pathways for HSBP1
        HSF1-dependent transactivation
    HSF1 activation
    Attenuation phase



    HSBP1 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HSBP1
    Interactions:

        GeneGlobe Interaction Network for HSBP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    Selected Interacting proteins for HSBP1 (O755062, 3 ENSP000003928964) via UniProtKB, MINT, STRING, and/or I2D (see all 23)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HSPA1AP081073, ENSP000003648024I2D: score=2 STRING: ENSP00000364802
    ENSG00000212866P081073I2D: score=2 
    ENSG00000215328P081073I2D: score=2 
    ENSG00000224501P081073I2D: score=2 
    ENSG00000231555P081073I2D: score=2 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter TAS9649501
    GO:0006936muscle contraction IEA--

    HSBP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HSBP1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for HSBP1 gene: 
    NM_001537.3  

    Unigene Cluster for HSBP1:

    Heat shock factor binding protein 1
    Hs.250899  [show with all ESTs]
    Unigene Representative Sequence: BX648254
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000433866(uc002fgy.1) ENST00000570259 ENST00000567382 ENST00000569301
    ENST00000567125
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat HSBP1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HSBP1 (see all 32):
    hsa-miR-1271 hsa-miR-374a hsa-miR-449a hsa-miR-3167 hsa-miR-421 hsa-miR-1244 hsa-miR-649 hsa-miR-1323
    SwitchGear 3'UTR luciferase reporter plasmidHSBP1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat HSBP1
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    GenScript: all cDNA clones in your preferred vector: HSBP1 (NM_001537)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HSBP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSBP1
    Primer
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    OriGene qPCR primer pairs and template standards for HSBP1
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      QuantiTect SYBR Green Assays in human, mouse, rat HSBP1
      QuantiFast Probe-based Assays in human, mouse, rat HSBP1

    Additional mRNA sequence: 

    AF068754.1 AK026575.1 AK172732.1 AY320409.1 BC007515.2 BX537440.1 BX648254.1 BX648972.1 

    Selected DOTS entries (see all 30):

    DT.95210384  DT.420246  DT.95118674  DT.100038497  DT.100883179  DT.100883187  DT.92448229  DT.86850064 
    DT.86855778  DT.100883177  DT.100883184  DT.100766147  DT.100883181  DT.120659343  DT.120659348  DT.121275731 
    DT.95344631  DT.100883178  DT.100883185  DT.120659312  DT.120659357  DT.307968  DT.87079489  DT.91953433 

    Selected AceView cDNA sequences (see all 750):

    BQ048956 BM509775 BU159732 CA440363 BQ007362 BQ182002 H88466 BU166614 
    AA397537 AW591625 AA490864 AJ711443 AI686845 T31455 CD368362 T31993 
    AJ709719 AA826413 CB136333 CR613945 CA440978 BM837004 AA737423 AA576681 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HSBP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATAAAGGTG
    HSBP1 Expression
    About this image

    HSBP1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HSBP1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.250899
        Custom PCR Arrays for HSBP1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSBP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for HSBP1 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hsbp11 , 5 heat shock factor binding protein 11, 5 85.09(n)1
    88.16(a)1
      8 (67.54 cM)5
    681961  NM_024219.11  NP_077181.11 
     1193445385 
    chicken
    (Gallus gallus)
    Aves HSBP11 heat shock factor binding protein 1 80.37(n)
    94.52(a)
      415813  NM_001112809.1  NP_001106280.1 
    lizard
    (Anolis carolinensis)
    Reptilia HSBP16
    heat shock factor binding protein 1
    84(a)
    1 ↔ 1
    GL343849.1(126730-129488)
    African clawed frog
    (Xenopus laevis)
    Amphibia BX854812.12   -- 82.98(n)    BX854812.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc732242 hypothetical protein MGC73224 82.78(n)   393727  BC059566.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG54466
    --
    52(a)
    1 ↔ 1
    2L(12426631-12427709)
    worm
    (Caenorhabditis elegans)
    Secernentea hsb-16
    Protein HSB-1 (hsb-1) mRNA, complete cds
    46(a)
    1 ↔ 1
    IV(12565993-12567228) WBGene00002002


    ENSEMBL Gene Tree for HSBP1 (if available)
    TreeFam Gene Tree for HSBP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HSBP1 gene
    1 SIMAP similar gene for HSBP1 using alignment to 2 protein entries:     HSBP1_HUMAN (see all proteins):
    HSBP1L1

    HSBP1 for paralogs           About GeneDecksing


    3 Pseudogenes.org Pseudogenes for HSBP1
    PGOHUM00000248188 PGOHUM00000250728 PGOHUM00000235357


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HSBP1 (see all 172)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1875429201,2
    --83839532(+) GAACCA/GGGGAG 1 -- us2k10--------
    rs349262901,2
    C--83839628(+) AAAAA-/AAAAGT 1 -- us2k11Minor allele frequency- A:0.50NA 2
    rs1444889941,2
    C--83839713(+) GGGTGC/TCCCCT 1 -- us2k10--------
    rs1165948441,2
    F--83839739(+) AAGAAC/TGACTT 1 -- us2k11Minor allele frequency- T:0.01WA 118
    rs1924635961,2
    --83839898(+) GTTTCC/TTAACG 1 -- us2k10--------
    rs758790701,2
    F--83839962(+) TCTTCT/CGAGGA 1 -- us2k11Minor allele frequency- C:0.02EA 120
    rs1466183481,2
    --83839989(+) AGATAC/TTTTTA 1 -- us2k10--------
    rs1838010471,2
    --83840032(+) ACCAGC/TTGACA 1 -- us2k10--------
    rs1398864701,2
    --83840047(+) CCAATA/TACAAA 1 -- us2k10--------
    rs1498144971,2
    --83840059(+) AAGTTC/GTGTAT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for HSBP1 (83841448 - 83853342 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for HSBP1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv1907CNV Insertion18451855
    nsv833308CNV Loss17160897
    nsv907036CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing HSBP1
    DNA2.0 Custom Variant and Variant Library Synthesis for HSBP1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 604553    OMIM disorders: --

    3 diseases for HSBP1:    
    About MalaCards
    nasopharyngitis    breast cancer    neuronitis


    HSBP1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): HSBP1

    Export disorders for HSBP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HSBP1 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with HSBP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Negative regulation of the heat shock transcriptional response by HSBP1. (PubMed id 9649501)1, 2, 3 Satyal S.H.... Morimoto R.I. (Genes Dev. 1998)
    2. Crystal structure of the hexamer of human heat shock factor binding protein 1. (PubMed id 18767159)1, 2, 9 Liu X.... Rao Z. (Proteins 2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. The heat-shock response: regulation and function of heat-shock proteins and molecular chaperones. (PubMed id 9493008)1, 3 Morimoto R.I....Cotto J.J. (Essays Biochem. 1997)
    5. VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (PLoS ONE 2013)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    7. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    8. The heat shock-binding protein (HspBP1) protects cells against the cytotoxic action of the Tag7-Hsp70 complex. (PubMed id 21247889)1 Yashin D.V....Sashchenko L.P. (J. Biol. Chem. 2011)
    9. Genome-wide association for smoking cessation success: participants in the Patch in Practice trial of nicotine replacement. (PubMed id 20235792)4 Uhl G.R....MunafA^ M.R. (Pharmacogenomics 2010)
    10. Network organization of the human autophagy system. (PubMed id 20562859)1 Behrends C....Harper J.W. (Nature 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 3281 HGNC: 5203 AceView: HSBP1 Ensembl:ENSG00000230989 euGenes: HUgn3281
    ECgene: HSBP1 H-InvDB: HSBP1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for HSBP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for HSBP1 gene:
    Search GeneIP for patents involving HSBP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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