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HS1BP3 Gene

protein-coding   GIFtS: 53
GCID: GC02M020760

HCLS1 Binding Protein 3

Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
HCLS1 Binding Protein 31 2     HS1-BP32
HSP1BP-32 3     HCLS1-Binding Protein 32
HS1-Binding Protein 32 3     FLJ142495
ETM22 5     

External Ids:    HGNC: 249791   Entrez Gene: 643422   Ensembl: ENSG000001189607   OMIM: 6093595   UniProtKB: Q53T593   

Export aliases for HS1BP3 gene to outside databases

Previous GC identifers: GC02M020740 GC02M020682 GC02M020574


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for HS1BP3 Gene:
The protein encoded by this gene shares similarity with mouse Hs1bp3, an Hcls1/Hs1-interacting protein that may be
involved in lymphocyte activation. (provided by RefSeq, Jul 2008)

GeneCards Summary for HS1BP3 Gene:
HS1BP3 (HCLS1 binding protein 3) is a protein-coding gene. Diseases associated with HS1BP3 include bell's palsy, and dystonia musculorum deformans. GO annotations related to this gene include phosphatidylinositol binding.

UniProtKB/Swiss-Prot: H1BP3_HUMAN, Q53T59
Function: May be a modulator of IL-2 signaling (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000002.12  NC_018913.2  NT_022184.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the HS1BP3 gene promoter:
         Spz1   SREBP-1c   MyoD   AP-2gamma   Cdc5   SREBP-1b   SREBP-1a   AP-2beta   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHS1BP3 promoter sequence
   Search Chromatin IP Primers for HS1BP3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HS1BP3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p24.1   Ensembl cytogenetic band:  2p24.1   HGNC cytogenetic band: 2p24.1

HS1BP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HS1BP3 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M020760:  view genomic region     (about GC identifiers)

Start:
20,760,208 bp from pter      End:
20,850,864 bp from pter
Size:
90,657 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: H1BP3_HUMAN, Q53T59 (See protein sequence)
Recommended Name: HCLS1-binding protein 3  
Size: 392 amino acids; 42780 Da
Subunit: Binds HCLS1. Interacts with the SH3 domain of HCLS1 in vitro (By similarity)
Secondary accessions: B2RAW2 D6W529 Q86VC2 Q8N367

Explore the universe of human proteins at neXtProt for HS1BP3: NX_Q53T59

Explore proteomics data for HS1BP3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See HS1BP3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_071905.3  
    ENSEMBL proteins: 
     ENSP00000389960   ENSP00000387364   ENSP00000305193   ENSP00000392203   ENSP00000397546  
     ENSP00000384984   ENSP00000385788  

    HS1BP3 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR001683 Phox

    Graphical View of Domain Structure for InterPro Entry Q53T59

    ProtoNet protein and cluster: Q53T59

    1 Blocks protein domain: IPB001683 Phox-like

    UniProtKB/Swiss-Prot: H1BP3_HUMAN, Q53T59
    Similarity: Contains 1 PX (phox homology) domain


    HS1BP3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: H1BP3_HUMAN, Q53T59
    Function: May be a modulator of IL-2 signaling (By similarity)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0035091phosphatidylinositol binding IEA--
         
    HS1BP3 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HS1BP3
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HS1BP3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HS1BP3

    miRNA
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    miRTarBase miRNAs that target HS1BP3:
    hsa-mir-124-3p (MIRT023188)

    Block miRNA regulation of human, mouse, rat HS1BP3 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate HS1BP3:
    hsa-miR-124 hsa-miR-506 hsa-miR-3153
    SwitchGear 3'UTR luciferase reporter plasmidHS1BP3 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat HS1BP3

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    GenScript: all cDNA clones in your preferred vector: HS1BP3 (NM_022460)
    Browse Sino Biological Human cDNA Clones
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HS1BP3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HS1BP3
    Interactions:

        Search GeneGlobe Interaction Network for HS1BP3

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for HS1BP3 (Q53T593 ENSP000003051934) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HCLS1P143173, ENSP000003201764I2D: score=3 STRING: ENSP00000320176
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007154cell communication ----

    HS1BP3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HS1BP3 (H1BP3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for HS1BP3 gene: 
    NM_022460.3  

    Unigene Cluster for HS1BP3:

    HCLS1 binding protein 3
    Hs.531785  [show with all ESTs]
    Unigene Representative Sequence: BC050636
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000446825 ENST00000415264 ENST00000304031(uc002rdw.1) ENST00000458740
    ENST00000445102 ENST00000402541(uc002rdx.3) ENST00000406618(uc002rdy.3)


    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat HS1BP3 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate HS1BP3:
    hsa-miR-124 hsa-miR-506 hsa-miR-3153
    SwitchGear 3'UTR luciferase reporter plasmidHS1BP3 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for HS1BP3
    Predesigned siRNA for gene silencing in human, mouse, rat HS1BP3
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: HS1BP3 (NM_022460)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HS1BP3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HS1BP3
    Primer
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    OriGene qPCR primer pairs and template standards for HS1BP3
    OriGene qSTAR qPCR primer pairs in human, mouse for HS1BP3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat HS1BP3
      QuantiTect SYBR Green Assays in human, mouse, rat HS1BP3
      QuantiFast Probe-based Assays in human, mouse, rat HS1BP3

    Additional mRNA sequence: 

    AK024311.1 AK123411.1 AK314383.1 BC038847.1 BC050636.1 

    7 DOTS entries:

    DT.212322  DT.205801  DT.100726519  DT.95205905  DT.95293116  DT.95221633  DT.95118499 

    Selected AceView cDNA sequences (see all 126):

    BF340358 AA913385 BQ224426 AU134068 CR596701 NM_022460 BX345340 BC038847 
    NM_106552 AI476172 BG150469 AW452124 BE614988 BF590885 AW073365 BM970057 
    BU158263 BC050636 BQ884418 CA417312 AL525113 BQ675292 BQ674057 BE614835 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for HS1BP3 (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b
    SP1:                          -           -                       -               
    SP2:              -     -     -           -                                       
    SP3:              -           -           -                                       
    SP4:                          -                                                   
    SP5:                    -     -     -     -     -     -           -               


    ECgene alternative splicing isoforms for HS1BP3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HS1BP3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATTCTCTCAG
    HS1BP3 Expression
    About this image

    HS1BP3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HS1BP3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.531785
        Custom PCR Arrays for HS1BP3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HS1BP3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for HS1BP3 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hs1bp31 , 5 HCLS1 binding protein 31, 5 82.38(n)1
    77.46(a)1
      12 (3.85 cM)5
    582401  NM_021429.31  NP_067404.21 
     83134335 
    chicken
    (Gallus gallus)
    Aves HS1BP31 HCLS1 binding protein 3 62.1(n)
    58.53(a)
      421966  XM_419977.4  XP_419977.4 
    lizard
    (Anolis carolinensis)
    Reptilia HS1BP36
    HCLS1 binding protein 3
    53(a)
    1 ↔ 1
    1(155443889-155487551)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.327922 Xenopus laevis transcribed sequence with weak similarity more 73.93(n)    CA790454.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5532231 HCLS1 binding protein 3 52.22(n)
    43.64(a)
      553223  NM_001256221.1  NP_001243150.1 


    ENSEMBL Gene Tree for HS1BP3 (if available)
    TreeFam Gene Tree for HS1BP3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HS1BP3 (see all 897)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs67393571,2
    C,F,A--20817070(+) CGGGTG/ATGAAG 1 -- ds50013Minor allele frequency- A:0.07NA CSA WA 122
    rs732350631,2
    C,F--20817089(+) CAAATG/AGGTGG 1 -- ds50013Minor allele frequency- A:0.03WA NA 240
    rs1932245121,2
    --20817099(+) GAGCCA/GGTGCT 1 -- ds50010--------
    rs344052901,2
    C--20817188(+) AGTCAG/CCTCTC 1 -- ds50015Minor allele frequency- C:0.16NA WA EA 362
    rs1382956161,2
    --20817260(+) AGGGCC/GCCACA 1 -- ds50010--------
    rs350016061,2
    C--20817261(+) GGGCGC/GCACAG 1 -- ds50015Minor allele frequency- G:0.16NA WA EA 362
    rs1143499371,2
    C,F--20817279(+) GGGACG/ATGATC 1 -- ds50011Minor allele frequency- A:0.02WA 118
    rs732350641,2
    C--20817317(+) GGCACG/AGGCCA 1 -- ds50012Minor allele frequency- A:0.06WA 120
    rs357559271,2
    C--20817362(+) CACCCG/ACACCA 1 -- ds50016Minor allele frequency- A:0.17NA WA EA 364
    rs584497301,2
    C--20817393(+) TTTGGCTTTGG/-
            
    TGTCT
    1 -- cds11Minor allele frequency- -:0.00NA 2

    HapMap Linkage Disequilibrium report for HS1BP3 (20760208 - 20850864 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for HS1BP3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv272408CNV Insertion20981092
    nsv508828CNV Insertion20534489
    dgv4069n71CNV Loss21882294
    dgv56n68CNV Loss17160897
    nsv527901CNV Loss19592680
    nsv517472CNV Loss19592680
    nsv873725CNV Loss21882294

    Human Gene Mutation Database (HGMD): HS1BP3
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing HS1BP3
    DNA2.0 Custom Variant and Variant Library Synthesis for HS1BP3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609359    OMIM disorders: --

    5 diseases for HS1BP3:    About MalaCards
    bell's palsy    dystonia musculorum deformans    essential tremor    tremor
    parkinson's disease

    2 diseases from the University of Copenhagen DISEASES database for HS1BP3:
    Essential tremor     Dystonia musculorum deformans

    HS1BP3 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): HS1BP3
    Human Genome Epidemiology (HuGE) Navigator: HS1BP3 (1 document)

    Export disorders for HS1BP3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HS1BP3 gene, integrated from 10 sources (see all 20):
    (articles sorted by number of sources associating them with HS1BP3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A variant in the HS1-BP3 gene is associated with familial essential tremor. (PubMed id 15699368)1, 3, 9 Higgins J.J....Rooney J.P. (Neurology 2005)
    2. DRD3 Ser9Gly and HS1BP3 Ala265Gly are not associated with Parkinson disease. (PubMed id 19524641)1, 4 Keeling B.H....Farrer M.J. (Neurosci. Lett. 2009)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Isolation and characterization of a novel HS1 SH3 domain binding protein, HS1BP3. (PubMed id 10590261)1, 3 Takemoto Y....Hashimoto Y. (Int. Immunol. 1999)
    5. VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (PLoS ONE 2013)
    6. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    8. Human HS1BP3 induces cell apoptosis and activates AP-1. (PubMed id 21699750)1 Shi T....Ma D. (BMB Rep 2011)
    9. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    10. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 64342 HGNC: 24979 AceView: FLJ14249 Ensembl:ENSG00000118960 euGenes: HUgn64342
    ECgene: HS1BP3 H-InvDB: HS1BP3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HS1BP3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for HS1BP3 gene:
    Search GeneIP for patents involving HS1BP3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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