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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HRSP12 Gene

protein-coding   GIFtS: 53
GCID: GC08M099183

heat-responsive protein 12
 Explore 12 diseases affiliated with
HRSP12 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for HRSP12    

Aliases
for HRSP12 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Heat-Responsive Protein 121 2 3     Perchloric Acid-Soluble Protein2
PSP1 2 3 5     Ribonuclease UK1142
UK1141 2 5     Translational Inhibitor P14.52
P14.51 2     Translational Inhibitor Protein P14.52
14.5 KDa Translational Inhibitor Protein2 3     EC 3.1.-.-3
UK114 Antigen Homolog2 3     P14.51 2

External Ids:    HGNC: 168971   Entrez Gene: 102472   Ensembl: ENSG000001325417   OMIM: 6024875   UniProtKB: P527583   

Export aliases for HRSP12 gene to outside databases

Previous GC identifers: GC08M099072 GC08M094318


Summaries
for HRSP12 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: UK114_HUMAN, P52758
Function: Endoribonuclease responsible for the inhibition of the translation by cleaving mRNA. Inhibits cell-free
protein synthesis. Cleaves phosphodiester bonds only in single-stranded RNA (By similarity)

Gene Wiki entry for HRSP12 (Heat-responsive protein 12)


Genomic Views
for HRSP12 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NC_018919.1  NT_008046.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HRSP12 gene promoter:
         MEF-2   MEF-2A   PPAR-gamma1   POU2F1   POU2F1a   FOXO4   PPAR-gamma2   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: HRSP12 promoter sequence
   Search SABiosciences Chromatin IP Primers for HRSP12

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HRSP12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q22   Ensembl cytogenetic band:  8q22.2   HGNC cytogenetic band: 8q22

HRSP12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HRSP12 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M099183:  view genomic region     (about GC identifiers)

Start:
 99,114,567 bp from pter      End:
 99,129,469 bp from pter
Size:
 14,903 bases      Orientation:
 minus strand

Proteins
for HRSP12 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: UK114_HUMAN, P52758 (See protein sequence)
Recommended Name: Ribonuclease UK114  
Size: 137 amino acids; 14494 Da
Subunit: Homotrimer
Subcellular location: Cytoplasm. Nucleus. Note=Mostly cytoplasmic but, in less differentiated cells occasionally
nuclear
Developmental stage: Up-regulated during cellular differentiation
1 PDB 3D structure from and Proteopedia for HRSP12:
1ONI (3D)    
Secondary accessions: Q6FHU9 Q6IBG0

Explore the universe of human proteins at neXtProt for HRSP12: NX_P52758

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P52758

    • HRSP12 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_005827.1  
    ENSEMBL proteins: 
     ENSP00000254878   ENSP00000429321   ENSP00000428596   ENSP00000430482   ENSP00000429536  

    Human Recombinant Protein Products: 
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    OriGene Protein Over-expression Lysate: HRSP12
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    Novus Biologicals HRSP12 Proteins
    Novus Biologicals HRSP12 Lysate
    Browse Sino Biological Recombinant Proteins
    ProSpec Recombinant Protein for HRSP12
    Uscn Proteins for HRSP12

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005739mitochondrion IEA--


    HRSP12 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for HRSP12

    Protein Domains /
    Families
    for HRSP12 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HRSP12 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR006056 YjgF-like
     IPR013813 Endoribo_LPSP/chorism_mut-like
     IPR019897 YjgF-like_CS
     IPR006175 YjgF/Yer057p/UK114

    Graphical View of Domain Structure for InterPro Entry P52758

    ProtoNet protein and cluster: P52758

    2 Blocks protein families:
    IPB006056 YjgF-like protein
    IPB006175 Endoribonuclease L-PSP


    UniProtKB/Swiss-Prot: UK114_HUMAN, P52758
    Similarity: Belongs to the RutC family


    Function
    for HRSP12 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: UK114_HUMAN, P52758
    Function: Endoribonuclease responsible for the inhibition of the translation by cleaving mRNA. Inhibits cell-free
    protein synthesis. Cleaves phosphodiester bonds only in single-stranded RNA (By similarity)

    Enzyme Number (IUBMB): EC 3.1.-.-1

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HRSP12
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate HRSP12:
    hsa-miR-587 hsa-miR-885-5p hsa-miR-590-3p
    SwitchGear 3'UTR luciferase reporter plasmid: HRSP12 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HRSP12 (see all 7)
    OriGene shRNA RFP: HRSP12
    OriGene siRNA: HRSP12
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HRSP12

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for HRSP12

    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for HRSP12

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HRSP12

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004519endonuclease activity IEA--


    HRSP12 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for HRSP12:
     Increased cell number in S  Synthetic lethal with Ras 


    Pathways & Interactions
    for HRSP12 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HRSP12

    STRING Interaction Network Preview (showing 5 interactants - click image to see 18)

    5/20 Interacting proteins for HRSP12 (P527583 ENSP000002548784) via UniProtKB, MINT, STRING, and/or I2D (see all 20)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TRIB3Q96RU73, ENSP000002172334I2D: score=1 STRING: ENSP00000217233
    SGTAO437653, ENSP000002215664I2D: score=1 STRING: ENSP00000221566
    TRAPPC3O436173I2D: score=5 
    DLG4P783523I2D: score=1 
    HPDENSP000002890044STRING: ENSP00000289004
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006449regulation of translational termination TAS8530410


    HRSP12 for ontologies           About GeneDecksing



    Drugs & Compounds
    for HRSP12 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    HRSP12 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HRSP12

    1 DrugBank Compound for HRSP12    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Benzoic Acid-- 65-85-0target--17139284 17016423

    2 Novoseek chemical compound relationships for HRSP12 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    perchloric acid 76.4 6 9767104 (1), 19358150 (1), 14656903 (1), 16602700 (1) (see all 6)
    fatty acid 3.38 2 14624641 (1)

    Search CenterWatch for drugs/clinical trials and news about HRSP12 / UK114 

    Transcripts
    for HRSP12 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for HRSP12 gene: 
    NM_005836.2  

    Unigene Cluster for HRSP12:

    Heat-responsive protein 12
    Hs.18426  [show with all ESTs]
    Unigene Representative Sequence: BF217184
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000254878(uc003yii.1) ENST00000522791 ENST00000520507 ENST00000521560
    ENST00000519608 ENST00000520989 ENST00000519155

    miRNA
    Products:             		 OriGene 3'-UTR Clone: HRSP12
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HRSP12
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate HRSP12:
    hsa-miR-587 hsa-miR-885-5p hsa-miR-590-3p
    SwitchGear 3'UTR luciferase reporter plasmid: HRSP12 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HRSP12 (see all 7)
    OriGene shRNA RFP: HRSP12
    OriGene siRNA: HRSP12
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HRSP12
    Clone
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    GenScript: all cDNA clones in your preferred vector: HRSP12 (NM_005836)
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HRSP12
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HRSP12

    Additional cDNA sequence: 

    BC010280.1 BC012592.1 BC093059.1 CR456844.1 CR541652.1 X95384.1 

    6 DOTS entries:

    DT.117213  DT.100790756  DT.40109059  DT.91767131  DT.100692150  DT.95168545 

    24/223 AceView cDNA sequences (see all 223):

    AU145094 NM_005836 AI802895 BX115555 AI374595 AV682845 AV682766 AA343981 
    CD676283 BM783899 X95384 CB163727 BM971137 CB055150 AI743799 R91820 
    AW080496 BI826873 BM840208 CA438902 BE501887 CR619148 BI758941 AI301696 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for HRSP12    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b · 2c ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d
    SP1:                          -                 -                                             
    SP2:                          -     -           -                                             
    SP3:                          -     -     -     -                                             
    SP4:                                                                                          
    SP5:                                            -                                             


    ECgene alternative splicing isoforms for HRSP12

    Expression
    for HRSP12 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HRSP12 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AATATTAGAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    HRSP12 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    3 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Gut TubeMidgutMidgut Endoderm CellsEndoderm
    Gut TubeMidgutGut Tube
    KidneyMetanephrosKidney
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See HRSP12 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HRSP12

    SOURCE GeneReport for Unigene cluster: Hs.18426

    UniProtKB/Swiss-Prot: UK114_HUMAN, P52758
    Tissue specificity: Hepatocytes and renal distal tubular epithelial cells. Only weak expression in other tissues

        SABiosciences Custom PCR Arrays for HRSP12
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    In Situ
    Assay Products:     
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    Orthologs
    for HRSP12 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the last universal common ancestor (LUCA).

    Orthologs for HRSP12 gene from 11/38 species (see all 38)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Hrsp121 , 5 heat-responsive protein 121, 5 84.94(n)1
    81.48(a)1    		   15 (14.34 cM)5
    154731  NM_008287.31  NP_032313.21 
     344840215 
    chicken
    (Gallus gallus)    		 Aves HRSP121 heat-responsive protein 12 72.47(n)
    72.73(a)    		   426536  XM_001234688.2  XP_001234689.2 
    lizard
    (Anolis carolinensis)    		 Reptilia HRSP126
    		 --
    		 65(a)
    		 1 ↔ 1
    		 4(20683734-20687723)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.83122 Xenopus laevis transcribed sequence with moderate similarity more 76.06(n)    BU905542.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii Dr.185142 Transcribed sequence with moderate similarity to protein more 73.85(n)    AI877744.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta UK1141 CG15261-PA 52.07(n)
    46.72(a)    		   34897  NM_135903.2  NP_609747.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea CELE_C23G10.21 Protein C23G10.2 64.29(n)
    66.67(a)    		   182812  NM_001026008.3  NP_001021179.1 
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes MMF1(YIL051C)4
    HMF11    		 Mitochondrial protein required for transamination of more4
    Hmf1p1    		 51.59(n)1
    41.74(a)1    		   9(258280-257843)4
    8567851  NP_010978.31  8547604 
     NP_012213.14 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT3G203901 endoribonuclease L-PSP family protein 57.67(n)
    54.76(a)    		   821584  NM_112930.2  NP_188674.1 
    rice
    (Oryza sativa)    		 Liliopsida Os07g05162001 hypothetical protein 57.1(n)
    52.46(a)    		   4343379  NM_001066316.1  NP_001059781.1 


    ENSEMBL Gene Tree for HRSP12 (if available)
    TreeFam Gene Tree for HRSP12 (if available) 

    Paralogs
    for HRSP12 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HRSP12 gene

    HRSP12 for paralogs           About GeneDecksing


    4 Pseudogenes.org Pseudogenes for HRSP12
    PGOHUM00000256754 PGOHUM00000256885 PGOHUM00000245464 PGOHUM00000236433


    Genomic Variants
    for HRSP12 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/316 NCBI SNPs in HRSP12 are shown (see all 316)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 8 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1888541241,2
    		--99114183(+) GCAGGC/TGGATC 1 -- ds50010--------
    rs117867711,2
    		C,F,A,H,--99114190(+) GATCAG/TGAGGT 1 -- ds50014Minor allele frequency- T:0.50NA 8
    rs1930639001,2
    		--99114224(+) TAACTC/TGGTGA 1 -- ds50010--------
    rs2020166461,2
    		--99114253(+) AATAT-/AAAAAA 1 -- ds50010--------
    rs1464088301,2
    		--99114344(+) GAGGCA/GGAGCG 1 -- ds50010--------
    rs1848215211,2
    		--99114697(+) CATAAC/TGGACA 1 -- ut310--------
    rs737012501,2
    		C,F,--99114768(+) GAATAA/C/GTAACT 2 -- ut315WA CSA NA 243
    rs1880173671,2
    		--99114770(+) ATAGTA/CACTCT 1 -- ut310--------
    rs1913703531,2
    		--99114846(+) ATTCAA/GTAATA 1 -- ut310--------
    rs82181,2
    		C,F,O,A,H,--99114970(-) GACAGT/GGTGAG 1 -- ut31 ese334Minor allele frequency- G:0.17MN EA NA NS CSA WA 3773

    HapMap Linkage Disequilibrium report for HRSP12 (99114567 - 99129469 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for HRSP12: --

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for HRSP12 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    HRSP12 for disorders           About GeneDecksing

    OMIM gene information: 602487    OMIM disorders: --

    12 diseases for HRSP12:    About MalaCards
    tick-borne encephalitis    murray valley encephalitis    louping ill    encephalitis
    leukodystrophy    pulmonary tuberculosis    lung adenocarcinoma    tuberculosis
    lung cancer    adenocarcinoma    pneumonia    carcinoma

    3 Novoseek disease relationships for HRSP12 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 0 4 9405234 (1), 17289870 (1)
    carcinoma 0 1 10408693 (1)
    cancer 0 7 9767104 (1), 15359725 (1), 9463573 (1), 10066372 (1)

    Human Genome Epidemiology (HuGE) Navigator: HRSP12 (1 document)

    Export disorders for HRSP12 gene to outside databases

    Publications
    for HRSP12 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HRSP12 gene, integrated from 9 sources (see all 46):
    (articles sorted by number of sources associating them with HRSP12)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation and characterization of a 14.5-kDa trichloroacetic-acid- soluble translational inhibitor protein from human monocytes that is upregulated upon cellular differentiation. (PubMed id 8973653)1, 2, 3, 9 Schmiedeknecht G.... Schmitz G. (1996)
    2. A bidirectional promoter connects the p14.5 gene to the gene for RNase P and RNase MRP protein subunit hPOP1. (PubMed id 9405234)1, 3, 9 Schmiedeknecht G.... Schmitz G. (1997)
    3. Crystal structure of Homo sapiens protein hp14.5. (PubMed id 14997576)1, 2 Manjasetty B.A.... Heinemann U. (2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. cDNA cloning and Escherichia coli expression of UK114 tumor antigen. (PubMed id 9767104)1, 9 Colombo I....Berra B. (1998)
    6. Structure-based ligand binding sites of protein p14.5, a member of protein family YER057c/YIL051c/YjgF. (PubMed id 16198412)1, 9 Mistiniene E....Naktinis V. (2005)
    7. Growth inhibition of DMBA-induced rat mammary carcinomas by UK 114. (PubMed id 9463573)1, 9 Racca S....Bussolati G. (1997)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    9. Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)
    10. Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP. (PubMed id 22210626)1 Mead S....Collinge J. (2012)

    External Searches for HRSP12 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Aliases
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    Genome Databases showing HRSP12 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10247 HGNC: 16897 AceView: HRSP12 Ensembl:ENSG00000132541 euGenes: HUgn10247
    ECgene: HRSP12 H-InvDB: HRSP12

    Other Databases showing HRSP12 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing HRSP12 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HRSP12 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for HRSP12 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for HRSP12 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for HRSP12 gene:
    Search GeneIP for patents involving HRSP12

    GeneCards and IP:
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