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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HRSP12 Gene

protein-coding   GIFtS: 58
GCID: GC08M099183

Heat-Responsive Protein 12

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Heat-Responsive Protein 121 2 3     P14.52
PSP2 3 5     Perchloric Acid-Soluble Protein2
Translational Inhibitor P14.51 2     Ribonuclease UK1142
14.5 KDa Translational Inhibitor Protein2 3     Translational Inhibitor Protein P14.52
UK114 Antigen Homolog2 3     EC 3.1.-.-3
UK1142 5     p14.53

External Ids:    HGNC: 168971   Entrez Gene: 102472   Ensembl: ENSG000001325417   OMIM: 6024875   UniProtKB: P527583   

Export aliases for HRSP12 gene to outside databases

Previous GC identifers: GC08M099072 GC08M094318


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for HRSP12 Gene: 
HRSP12 (heat-responsive protein 12) is a protein-coding gene. Diseases associated with HRSP12 include louping ill, and murray valley encephalitis. GO annotations related to this gene include endonuclease activity.

UniProtKB/Swiss-Prot: UK114_HUMAN, P52758
Function: Endoribonuclease responsible for the inhibition of the translation by cleaving mRNA. Inhibits cell-free
protein synthesis. Cleaves phosphodiester bonds only in single-stranded RNA (By similarity)

Gene Wiki entry for HRSP12 (Heat-responsive protein 12) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NC_018919.2  NT_008046.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HRSP12 gene promoter:
         MEF-2   MEF-2A   PPAR-gamma1   POU2F1   POU2F1a   FOXO4   PPAR-gamma2   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHRSP12 promoter sequence
   Search SABiosciences Chromatin IP Primers for HRSP12

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HRSP12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q22   Ensembl cytogenetic band:  8q22.2   HGNC cytogenetic band: 8q22

HRSP12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HRSP12 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M099183:  view genomic region     (about GC identifiers)

Start:
99,114,567 bp from pter      End:
99,129,469 bp from pter
Size:
14,903 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: UK114_HUMAN, P52758 (See protein sequence)
Recommended Name: Ribonuclease UK114  
Size: 137 amino acids; 14494 Da
Subunit: Homotrimer
Subcellular location: Cytoplasm. Nucleus. Note=Mostly cytoplasmic but, in less differentiated cells occasionally
nuclear
Developmental stage: Up-regulated during cellular differentiation
1 PDB 3D structure from and Proteopedia for HRSP12:
1ONI (3D)    
Secondary accessions: Q6FHU9 Q6IBG0

Explore the universe of human proteins at neXtProt for HRSP12: NX_P52758

Explore proteomics data for HRSP12 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P52758

  • HRSP12 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    HRSP12 Protein Expression
    REFSEQ proteins: NP_005827.1  
    ENSEMBL proteins: 
     ENSP00000254878   ENSP00000429321   ENSP00000428596   ENSP00000430482  

    Human Recombinant Protein Products for HRSP12: 
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    Novus Biologicals HRSP12 Proteins
    Novus Biologicals HRSP12 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    ProSpec Recombinant Protein for HRSP12
    Cloud-Clone Corp. Proteins for HRSP12 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005739mitochondrion IEA--

    HRSP12 for ontologies           About GeneDecksing



    HRSP12 Antibody Products: 
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    Cloud-Clone Corp. CLIAs for HRSP12


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR006056 YjgF-like
     IPR013813 Endoribo_LPSP/chorism_mut-like
     IPR019897 YjgF-like_CS
     IPR006175 YjgF/Yer057p/UK114

    Graphical View of Domain Structure for InterPro Entry P52758

    ProtoNet protein and cluster: P52758

    2 Blocks protein domains:
    IPB006056 YjgF-like protein
    IPB006175 Endoribonuclease L-PSP


    UniProtKB/Swiss-Prot: UK114_HUMAN, P52758
    Similarity: Belongs to the RutC family


    HRSP12 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: UK114_HUMAN, P52758
    Function: Endoribonuclease responsible for the inhibition of the translation by cleaving mRNA. Inhibits cell-free
    protein synthesis. Cleaves phosphodiester bonds only in single-stranded RNA (By similarity)

         Enzyme Number (IUBMB): EC 3.1.-.-1

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004519endonuclease activity IEA--
    GO:0019239deaminase activity IEA--
         
    HRSP12 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for HRSP12:
     Increased cell number in S  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for HRSP12 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for HRSP12

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HRSP12 
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    miRNA
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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate HRSP12:
    hsa-miR-587 hsa-miR-885-5p hsa-miR-590-3p
    SwitchGear 3'UTR luciferase reporter plasmidHRSP12 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HRSP12


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HRSP12

    STRING Interaction Network Preview (showing 5 interactants - click image to see 18)

    5/20 Interacting proteins for HRSP12 (P527583 ENSP000002548784) via UniProtKB, MINT, STRING, and/or I2D (see all 20)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TRIB3Q96RU73, ENSP000002172334I2D: score=1 STRING: ENSP00000217233
    SGTAO437653, ENSP000002215664I2D: score=1 STRING: ENSP00000221566
    TRAPPC3O436173I2D: score=5 
    DLG4P783523I2D: score=1 
    HPDENSP000002890044STRING: ENSP00000289004
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006449regulation of translational termination TAS8530410

    HRSP12 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    HRSP12 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HRSP12 (UK114)

    1 DrugBank Compound for HRSP12    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Benzoic Acid-- 65-85-0target--17139284 17016423

    2 Novoseek inferred chemical compound relationships for HRSP12 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    perchloric acid 76.4 6 9767104 (1), 19358150 (1), 14656903 (1), 16602700 (1) (see all 6)
    fatty acid 3.38 2 14624641 (1)

    Search CenterWatch for drugs/clinical trials and news about HRSP12 / UK114

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for HRSP12 gene: 
    NM_005836.2  

    Unigene Cluster for HRSP12:

    Heat-responsive protein 12
    Hs.18426  [show with all ESTs]
    Unigene Representative Sequence: BF217184
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000254878(uc003yii.1) ENST00000522791 ENST00000520507 ENST00000521560
    ENST00000519608 ENST00000519155
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate HRSP12:
    hsa-miR-587 hsa-miR-885-5p hsa-miR-590-3p
    SwitchGear 3'UTR luciferase reporter plasmidHRSP12 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HRSP12
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HRSP12

    Additional mRNA sequence: 

    BC010280.1 BC012592.1 BC093059.1 CR456844.1 CR541652.1 X95384.1 

    6 DOTS entries:

    DT.117213  DT.100790756  DT.40109059  DT.91767131  DT.100692150  DT.95168545 

    24/223 AceView cDNA sequences (see all 223):

    BM986821 AI114566 BI826873 CR619148 BM840208 AI934022 AI374595 AI001025 
    AA343981 X95384 AV682766 BX374598 CB163727 AW103654 AV682845 CD676283 
    AA746151 CB155907 R91820 BE501887 BX115555 BM783899 N79841 CA438902 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for HRSP12    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b · 2c ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d
    SP1:                          -                 -                                             
    SP2:                          -     -           -                                             
    SP3:                          -     -     -     -                                             
    SP4:                                                                                          
    SP5:                                            -                                             


    ECgene alternative splicing isoforms for HRSP12

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HRSP12 expression in normal human tissues (normalized intensities)      HRSP12 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATATTAGAG
    HRSP12 Expression
    About this image


    HRSP12 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/8 selected tissues (see all 8) fully expand
     
     Gut Tube (Gastrointestinal Tract)    fully expand to see all 3 entries
             Hindgut
     
     Kidney (Urinary System)    fully expand to see all 2 entries
             Metanephros
             kidney ; cells in tubules   
     
     Lung (Respiratory System)    fully expand to see all 2 entries
             visceral organ/lung/right lung   
     
     Liver (Hepatobiliary System)
             Hepatocytes Liver Lobule
     
     Thymus (Hematopoietic System)
             Thymus

    See HRSP12 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HRSP12

    SOURCE GeneReport for Unigene cluster: Hs.18426

    UniProtKB/Swiss-Prot: UK114_HUMAN, P52758
    Tissue specificity: Hepatocytes and renal distal tubular epithelial cells. Only weak expression in other tissues

        SABiosciences Custom PCR Arrays for HRSP12
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HRSP12

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for HRSP12 gene from 10/25 species (see all 25)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hrsp121 , 5 heat-responsive protein 121, 5 84.94(n)1
    81.48(a)1
      15 (14.34 cM)5
    154731  NM_008287.31  NP_032313.21 
     344840215 
    chicken
    (Gallus gallus)
    Aves HRSP121 heat-responsive protein 12 72.47(n)
    72.73(a)
      426536  XM_001234688.2  XP_001234689.2 
    lizard
    (Anolis carolinensis)
    Reptilia HRSP126
    Uncharacterized protein
    67(a)
    1 ↔ 1
    4(20683734-20687723)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.83122 Xenopus laevis transcribed sequence with moderate similarity more 76.06(n)    BU905542.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.185142 Transcribed sequence with moderate similarity to protein more 73.85(n)    AI877744.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta UK1141 CG15261-PA 52.07(n)
    46.72(a)
      34897  NM_135903.2  NP_609747.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_C23G10.21 Protein C23G10.2 64.29(n)
    66.67(a)
      182812  NM_001026008.3  NP_001021179.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes MMF1(YIL051C)4
    HMF11
    Mitochondrial protein required for transamination of more4
    Hmf1p1
    51.59(n)1
    41.74(a)1
      9(258280-257843)4
    8567851  NP_010978.31  8547604 
     NP_012213.14 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G203901 endoribonuclease L-PSP family protein 57.67(n)
    54.76(a)
      821584  NM_112930.2  NP_188674.1 
    rice
    (Oryza sativa)
    Liliopsida Os07g05162001 hypothetical protein 57.1(n)
    52.46(a)
      4343379  NM_001066316.1  NP_001059781.1 


    ENSEMBL Gene Tree for HRSP12 (if available)
    TreeFam Gene Tree for HRSP12 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HRSP12 gene

    HRSP12 for paralogs           About GeneDecksing


    4 Pseudogenes.org Pseudogenes for HRSP12
    PGOHUM00000256754 PGOHUM00000256885 PGOHUM00000245464 PGOHUM00000236433


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/301 SNPs in HRSP12 are shown (see all 301)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1888541241,2
    --99114183(+) GCAGGC/TGGATC 1 -- ds50010--------
    rs117867711,2
    C,F,A,H--99114190(+) GATCAG/TGAGGT 1 -- ds50014Minor allele frequency- T:0.50NA 8
    rs1930639001,2
    --99114224(+) TAACTC/TGGTGA 1 -- ds50010--------
    rs2020166461,2
    C--99114253(+) AATAT-/AAAAAA 1 -- ds50010--------
    rs1464088301,2
    C--99114344(+) GAGGCA/GGAGCG 1 -- ds50010--------
    rs1848215211,2
    --99114697(+) CATAAC/TGGACA 1 -- ut310--------
    rs737012501,2
    C,F--99114768(+) GAATAA/C/GTAACT 2 -- ut315WA CSA NA 243
    rs1880173671,2
    C--99114770(+) ATAGTA/CACTCT 1 -- ut310--------
    rs1913703531,2
    --99114846(+) ATTCAA/GTAATA 1 -- ut310--------
    rs82181,2
    C,F,O,A,H--99114970(-) GACAGT/GGTGAG 1 -- ut31 ese334Minor allele frequency- G:0.17MN EA NA NS CSA WA 3773

    HapMap Linkage Disequilibrium report for HRSP12 (99114567 - 99129469 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for HRSP12:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv465746CNV Gain19166990
    nsv465747CNV Gain19166990
    nsv831405CNV Gain17160897
    nsv465745CNV Gain19166990

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 602487    OMIM disorders: --

    12 diseases for HRSP12:    About MalaCards
    louping ill    murray valley encephalitis    tick-borne encephalitis    pulmonary tuberculosis
    encephalitis    leukodystrophy    lung adenocarcinoma    prion disease
    pneumonia    tuberculosis    adenocarcinoma    lung cancer


    HRSP12 for disorders           About GeneDecksing

    3 Novoseek inferred disease relationships for HRSP12 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 0 4 9405234 (1), 17289870 (1)
    carcinoma 0 1 10408693 (1)
    cancer 0 7 9767104 (1), 15359725 (1), 9463573 (1), 10066372 (1)

    Genetic Association Database (GAD): HRSP12
    Human Genome Epidemiology (HuGE) Navigator: HRSP12 (1 document)

    Export disorders for HRSP12 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HRSP12 gene, integrated from 9 sources (see all 48):
    (articles sorted by number of sources associating them with HRSP12)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation and characterization of a 14.5-kDa trichloroacetic-acid- soluble translational inhibitor protein from human monocytes that is upregulated upon cellular differentiation. (PubMed id 8973653)1, 2, 3, 9 Schmiedeknecht G.... Schmitz G. (1996)
    2. A bidirectional promoter connects the p14.5 gene to the gene for RNase P and RNase MRP protein subunit hPOP1. (PubMed id 9405234)1, 3, 9 Schmiedeknecht G.... Schmitz G. (1997)
    3. Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP. (PubMed id 22210626)1, 4 Mead S....Collinge J. (2012)
    4. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    5. Crystal structure of Homo sapiens protein hp14.5. (PubMed id 14997576)1, 2 Manjasetty B.A.... Heinemann U. (2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. cDNA cloning and Escherichia coli expression of UK114 tumor antigen. (PubMed id 9767104)1, 9 Colombo I....Berra B. (1998)
    8. Structure-based ligand binding sites of protein p14.5, a member of protein family YER057c/YIL051c/YjgF. (PubMed id 16198412)1, 9 Mistiniene E....Naktinis V. (2005)
    9. Growth inhibition of DMBA-induced rat mammary carcinomas by UK 114. (PubMed id 9463573)1, 9 Racca S....Bussolati G. (1997)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10247 HGNC: 16897 AceView: HRSP12 Ensembl:ENSG00000132541 euGenes: HUgn10247
    ECgene: HRSP12 H-InvDB: HRSP12

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HRSP12 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for HRSP12 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for HRSP12 gene:
    Search GeneIP for patents involving HRSP12

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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