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Aliases for HRCT1 Gene

Aliases for HRCT1 Gene

  • Histidine Rich Carboxyl Terminus 1 2 3
  • Histidine-Rich Carboxyl Terminus Protein 1 3
  • LGLL338 3
  • PRO537 3
  • UNQ338 3

External Ids for HRCT1 Gene

Summaries for HRCT1 Gene

GeneCards Summary for HRCT1 Gene

HRCT1 (Histidine Rich Carboxyl Terminus 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HRCT1 Gene

Genomics for HRCT1 Gene

Regulatory Elements for HRCT1 Gene

Genomic Location for HRCT1 Gene

35,906,192 bp from pter
35,907,141 bp from pter
950 bases
Plus strand

Genomic View for HRCT1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for HRCT1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HRCT1 Gene

Proteins for HRCT1 Gene

  • Protein details for HRCT1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Histidine-rich carboxyl terminus protein 1
    Protein Accession:
    Secondary Accessions:
    • B7ZBJ1

    Protein attributes for HRCT1 Gene

    115 amino acids
    Molecular mass:
    13183 Da
    Quaternary structure:
    No Data Available

neXtProt entry for HRCT1 Gene

Proteomics data for HRCT1 Gene at MOPED

Post-translational modifications for HRCT1 Gene

No Post-translational modifications

Other Protein References for HRCT1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for HRCT1 Gene

Domains for HRCT1 Gene

Protein Domains for HRCT1 Gene


Suggested Antigen Peptide Sequences for HRCT1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with HRCT1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for HRCT1 Gene

Function for HRCT1 Gene

Animal Model Products

miRNA for HRCT1 Gene

miRTarBase miRNAs that target HRCT1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for HRCT1 Gene

Localization for HRCT1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for HRCT1 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for HRCT1 Gene COMPARTMENTS Subcellular localization image for HRCT1 gene
Compartment Confidence
extracellular 3
cytosol 1
endoplasmic reticulum 1
lysosome 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for HRCT1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with HRCT1: view

Pathways for HRCT1 Gene

SuperPathways for HRCT1 Gene

No Data Available

Interacting Proteins for HRCT1 Gene

Gene Ontology (GO) - Biological Process for HRCT1 Gene


No data available for Pathways by source for HRCT1 Gene

Transcripts for HRCT1 Gene

mRNA/cDNA for HRCT1 Gene

(1) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HRCT1 Gene

Histidine rich carboxyl terminus 1:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for HRCT1

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for HRCT1 Gene

No ASD Table

Relevant External Links for HRCT1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for HRCT1 Gene

mRNA expression in normal human tissues for HRCT1 Gene

mRNA differential expression in normal tissues according to GTEx for HRCT1 Gene

This gene is overexpressed in Artery - Tibial (5.7), Artery - Aorta (5.3), and Colon - Transverse (4.0).

Protein differential expression in normal tissues for HRCT1 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (69.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for HRCT1 Gene

SOURCE GeneReport for Unigene cluster for HRCT1 Gene Hs.208081

genes like me logo Genes that share expressions with HRCT1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for HRCT1 Gene

Orthologs for HRCT1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for HRCT1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia HRCT1 35
  • 96.9 (n)
  • 96.43 (a)
HRCT1 36
  • 95 (a)
(Mus musculus)
Mammalia Hrct1 16
(Canis familiaris)
Mammalia HRCT1 36
  • 63 (a)
Species with no ortholog for HRCT1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for HRCT1 Gene

Gene Tree for HRCT1 (if available)
Gene Tree for HRCT1 (if available)

Paralogs for HRCT1 Gene

No data available for Paralogs for HRCT1 Gene

Variants for HRCT1 Gene

Sequence variations from dbSNP and Humsavar for HRCT1 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs2025175 -- 35,905,969(+) GCGGA(A/G)AGGGA upstream-variant-2KB
rs2236325 -- 35,907,363(+) AGCAG(A/G)TCCTG downstream-variant-500B
rs7852213 -- 35,906,568(+) CCCCC(A/G)CCACA missense, reference
rs10814293 -- 35,904,949(+) GATCA(A/G)GGCAA upstream-variant-2KB
rs10814294 -- 35,905,053(+) ATGAG(A/C)CTGGA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for HRCT1 Gene

Variant ID Type Subtype PubMed ID
dgv8168n71 CNV Gain 21882294
nsv831546 CNV Loss 17160897

Relevant External Links for HRCT1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HRCT1 Gene

Disorders for HRCT1 Gene

No disorders were found for HRCT1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for HRCT1 Gene

Publications for HRCT1 Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 4
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 4

Products for HRCT1 Gene

Sources for HRCT1 Gene

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