HR Gene
protein-coding GIFtS: 55
GCID: GC08M022028
|
|
hair growth associated(Previous names: hairless (mouse) homolog, hairless homolog (mouse) )
(Previous symbol: ALUNC)
| |
Aliases
for HR gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Hair Growth Associated1 2 | | Hairless Homolog (Mouse)1 | | AU1 2 5 | | HSA2771652 | | ALUNC1 2 | | MUHH2 | | MUHH12 5 | | Hairless Homolog2 | | Hairless (Mouse) Homolog1 | | Protein Hairless2 |
Export aliases for HR gene to outside databasesPrevious GC identifers: GC08M021730 GC08M022324 GC08M021792 GC08M021994 GC08M020514 |
Summaries
for HR gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for HR:
This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor ofmultiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor-related orphan receptorsand the vitamin D receptors, and it interacts with histone deacetylases. The translation of this protein is modulatedby multiple regulatory ORFs that exist upstream of the primary ORF. Mutations in one of these upstream ORFs, U2HR,cause Marie Unna hereditary hypotrichosis (MUHH), an autosomal dominant form of genetic hair loss. Mutations in thisgene also cause autosomal recessive congenital alopecia and atrichia with papular lesions, other diseases resulting inhair loss. Two transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Feb2009)
UniProtKB/Swiss-Prot: HAIR_HUMAN, O43593Function: May act as a transcription factor that could act on to regulate one of the phases of hair growth
Gene Wiki entry for HR
|
Genomic Views
for HR gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_167187.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the HR gene promoter:
GR AhR p53 AP-1 GR-alpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for HR
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HR |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8p21.2 Ensembl cytogenetic band: 8p21.3 HGNC cytogenetic band: 8p12HR Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08M022028: view genomic region
(about GC identifiers)
Start:
|
21,971,928 bp from pter |
End:
|
21,990,897 bp from pter |
Size:
|
18,970 bases |
Orientation:
|
minus strand |
|
Proteins
for HR gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: HAIR_HUMAN, O43593 (See
protein sequence)Recommended Name: Protein hairless Size: 1189 amino acids; 127495 Da
Subcellular location: Nucleus
Secondary accessions: Q6GS30 Q96H33 Q9NPE1Alternative splicing: 2 isoforms: O43593-1 O43593-2 Explore the universe of human proteins at neXtProt for HR: NX_O43593
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O43593
HR Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_005135.2 NP_060881.2
ENSEMBL proteins: ENSP00000370826 ENSP00000326765 ENSP00000430413
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
HR for ontologies About GeneDecksing
HR Antibody Products:
Assay Products for HR: |
Protein
Domains /
Families
for HR gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
HR for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry O43593ProtoNet protein and cluster: O43593 1 Blocks protein family: IPB003347 Transcription factor jumonji
UniProtKB/Swiss-Prot: HAIR_HUMAN, O43593Similarity: Contains 1 JmjC domain |
Function
for HR gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: HAIR_HUMAN, O43593Function: May act as a transcription factor that could act on to regulate one of the phases of hair growth Genatlas biochemistry entry for HR:hairless,putative transcription factor,mouse homolog,with two alternatively spliced isoforms,one containing exon17,expressed in all tissues but skin,the other lacking exon 17,specifically expressed in skin
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HR (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HR (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: HR (NM_001621) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HR | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HR |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HR |
Gene Ontology (GO): 5/8 molecular function terms (GO ID links to tree view) (see all 8): About this table
HR for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Hrtm1Cct for HR
15/17 MGI mutant phenotypes (inferred from 25 alleles ) (MGI details for Hr) (see all 17):
HR for phenotypes About GeneDecksing
|
Pathways & Interactions
for HR gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for HR
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/49 Interacting proteins for HR (O435932, 3 ENSP000003708264) via UniProtKB, MINT, STRING, and/or I2D (see all 49)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
NAS | 9445480 | | GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity |
-- | -- | | GO:0045892 | negative regulation of transcription, DNA-dependent |
IEA | -- | | GO:0051291 | protein heterooligomerization |
-- | -- |
HR for ontologies About GeneDecksing
|
Drugs & Compounds
for HR gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for HR
Search CenterWatch for drugs/clinical trials and news about HR / HAIR
|
Transcripts
for HR gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for HR gene (2 alternative transcripts): NM_005144.4 NM_018411.4 Unigene Cluster for HR: Hair growth associated Hs.272367 [show with all ESTs]Unigene Representative Sequence: AF0391969 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000381418(uc003xas.3) ENST00000312841(uc003xat.3) ENST00000522016
ENST00000522039 ENST00000517699 ENST00000518461 ENST00000519619 ENST00000522759(uc010lts.2)
ENST00000518377
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HR (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HR (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: HR (NM_001621) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HR | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HR |
Additional cDNA sequence: AF039196.3 AJ277165.2 BC008946.2 BC067128.1 10 DOTS entries: DT.91940379 DT.75198674 DT.40195765 DT.40281617 DT.40227638 DT.100728972 DT.100781950 DT.100781953 DT.120638295 DT.120638297 24/81 AceView cDNA sequences (see all 81): AK098053 BM799906 BQ961259 AI911834 AW295656 BM765508 BC067128 AA364375 NM_005144 AJ277165 AA227941 AL833253 NM_018411 BM716768 BF528023 BQ217662 AW001084 AW468652 AI669990 BF346259 BU196087 BG676789 AI269295 BM982749
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for HR (see all 8) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | · | 15c | ^ | 16 | ^ | 17a | · | 17b | ^ | 18a | · |
|---|
|
| SP1: | | | | | - | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 18b | ^ | 19 | ^ | 20 |
|---|
|
| SP1: | | | | | | | |
| SP2: | - | | | | | | |
| SP3: | | | | | | | |
| SP4: | | | | | | | |
| SP5: | | | | | | |
ECgene alternative splicing isoforms for HR
|
Expression
for HR gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| HR expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATTTCCATTA
About this image
See HR Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for HR
SOURCE GeneReport for Unigene cluster: Hs.272367
UniProtKB/Swiss-Prot: HAIR_HUMAN, O43593Tissue specificity: Strongest expression of isoforms 1 and 2 is seen in the small intestine, weaker expression in brainand colon, and trace expression is found in liver, pancreas, spleen, thymus, stomach, salivary gland, appendix andtrachea. Isoform 1 is always the most abundant. Isoform 1 is exclusively expressed at low levels in kidney and testis.Isoform 2 is exclusively expressed at high levels in the skin
SABiosciences Expression via Pathway-Focused PCR Array including HR:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HR
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat HR | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HR | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HR | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HR |
Orthologs
for HR gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for HR gene from 2/11 species (see all 11) About this table
ENSEMBL Gene Tree for HR (if available)
TreeFam Gene Tree for HR (if available) |
Paralogs
for HR gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for HR gene
- JMJD1C2 KDM3B2 KDM3A2
HR for paralogs About GeneDecksing
|
Genomic Variants
for HR gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for HR (21971928 - 21990897 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for HR
5 CNVs: 2746 30283 53638 3726 4586
Human Gene Mutation Database (HGMD): HR
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HR |
|
Disorders
/ Diseases
for HR gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
HR for disorders About GeneDecksing
OMIM gene information: 602302
OMIM disorders: 203655 209500 146550
UniProtKB/Swiss-Prot: HAIR_HUMAN, O43593
Defects in HR are the cause of alopecia universalis congenita (ALUNC) [MIM:203655]. ALUNC is a rare autosomalrecessive form of hair loss characterized by hair follicles without hair Defects in HR are the cause of atrichia with papular lesions (APL) [MIM:209500]; also known as congenitalatrichia. APL is an autosomal recessive disease characterized by papillary lesions over most of the body and almostcomplete absence of hair Defects in HR are the cause of hypotrichosis type 4 (HYPT4) [MIM:146550]. An autosomal dominant conditioncharacterized by reduced amount of hair, alopecia, little or no eyebrows, eyelashes or body hair, and coarse, wiry,twisted hair in early childhood
8  diseases for HR: About MalaCardsatrichia with papular lesions hypotrichosis, hereditary, marie unna type, 1 hypotrichosis alopecia
alopecia universalis androgenetic alopecia thyroiditis autosomal recessive disease
1 disease from the University of Copenhagen DISEASES database for HR:Alopecia 3 Novoseek disease relationships for HR gene About this table
Genetic Association Database (GAD): HR
Human Genome Epidemiology (HuGE) Navigator: HR (1242 documents)
Export disorders for HR gene to outside databases
|
Publications
for HR gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for HR gene, integrated from 9 sources (see all 52):
(articles sorted by number of sources associating them with HR) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Genomic organization of the human hairless gene (HR) and identification of a mutation underlying congenital atrichia in an Arab Palestinian family. (PubMed id 10051399)1, 2, 3, 9 Ahmad W.... Christiano A.M. (1999)
- The hairless gene in androgenetic alopecia: results of a systematic mutation screening and a family-based association approach. (PubMed id 11966690)1, 4, 9 Hillmer A.M....Cichon S. (2002)
- Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis. (PubMed id 19122663)1, 2 Wen Y.... Zhang X. (2009)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A novel missense mutation affecting the human hairless thyroid receptor interacting domain 2 causes congenital atrichia. (PubMed id 12406339)1, 2 Klein I.... Sprecher E. (2002)
- Variant 1859G-->A (Arg620Gln) of the 'hairless' gene: absence of association with papular atrichia or androgenic alopecia. (PubMed id 11410842)1, 2 Hillmer A.M.... Cichon S. (2001)
- Alopecia universalis associated with a mutation in the human hairless gene. (PubMed id 9445480)1, 2 Ahmad W.... Christiano A.M. (1998)
- A missense mutation in the zinc-finger domain of the human hairless gene underlies congenital atrichia in a family of Irish travellers. (PubMed id 9758627)1, 2 Ahmad W.... Christiano A.M. (1998)
- Cloning, genomic organization, alternative transcripts and mutational analysis of the gene responsible for autosomal recessive universal congenital alopecia. (PubMed id 9736769)1, 2 Cichon S.... Noethen M.M. (1998)
- A gene for universal congenital alopecia maps to chro mosome 8p21-22. (PubMed id 9463324)1, 3 NAPthen M.M....Rietschel M. (1998)
|
External Searches for HR gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing HR gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing HR gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing HR gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for HR | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/HR |
|
| | |
About This Section
| Patent Information for HR gene:
Search GeneIP for patents involving HR
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for HR gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for HR | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HR | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HR | | | OriGene Protein Over-expression Lysate for HR | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for HR | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HR | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HR | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for HR | | OriGene Custom Protein Services for HR | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HR | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HR | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HR | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HR | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HR | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HR |
| |
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| | | | Search Tocris compounds for HR |
| |  |  |  |  | | | | |
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 |
 | | | HR Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HR |
|  |  |  | | | | Search ThermoFisher Antibodies for HR |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HR |
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