HPS5 Gene
protein-coding GIFtS: 52
GCID: GC11M018300
|
|
Hermansky-Pudlak syndrome 5
| |
Aliases
for HPS5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Hermansky-Pudlak Syndrome 51 2 | | Alpha Integrin Binding Protein 632 | | Alpha-Integrin-Binding Protein 632 3 | | Hermansky-Pudlak Syndrome 5 Protein2 | | Ruby-Eye Protein 2 Homolog2 3 | | Ru23 | | AIBP632 3 | | RU25 | | KIAA10173 5 | | |
Export aliases for HPS5 gene to outside databasesPrevious GC identifers: GC00U991233 GC11M018339 GC11M018264 GC11M018256 GC11M017982 |
Summaries
for HPS5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for HPS5:
This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet densegranules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 6 protein and may interact with thecytoplasmic domain of integrin, alpha-3. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 5.Multiple transcript variants encoding two distinct isoforms have been identified for this gene. (provided by RefSeq,Jul 2008)
UniProtKB/Swiss-Prot: HPS5_HUMAN, Q9UPZ3Function: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such asmelanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involvedin the regulation of general functions of integrins
Gene Wiki entry for HPS5
|
Genomic Views
for HPS5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_009237.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the HPS5 gene promoter:
MyoD Lmo2 Cdc5 Tal-1beta GATA-1 Meis-1b MZF-1 Meis-1a ITF-2 Meis-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for HPS5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HPS5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11p14 Ensembl cytogenetic band: 11p15.1 HGNC cytogenetic band: 11p14HPS5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M018300: view genomic region
(about GC identifiers)
Start:
|
18,300,217 bp from pter |
End:
|
18,343,745 bp from pter |
Size:
|
43,529 bases |
Orientation:
|
minus strand |
|
Proteins
for HPS5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: HPS5_HUMAN, Q9UPZ3 (See
protein sequence)Recommended Name: Hermansky-Pudlak syndrome 5 protein Size: 1129 amino acids; 127449 Da
Subunit: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 andHPS6. Directly interacts with HPS6. May interact with all alpha-integrin chains that have an aromatic residue beforethe first lysine of the conserved KXGFFKR motif, including ITGA2, ITGA3, ITGA5 and ITGA6
Subcellular location: Cytoplasm, cytosol
Sequence caution: Sequence=BAA76861.2; Type=Erroneous initiation;
Secondary accessions: A8K6J8 A8K8S1 D3DQX9 D3DQY0 O95942 Q8N4U0Alternative splicing: 2 isoforms: Q9UPZ3-1 Q9UPZ3-2 Explore the universe of human proteins at neXtProt for HPS5: NX_Q9UPZ3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UPZ3
HPS5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_009147.3 NP_852608.1 NP_852609.1
ENSEMBL proteins: ENSP00000379552 ENSP00000265967 ENSP00000399590 ENSP00000437437 ENSP00000441781 ENSP00000431758
Human Recombinant Protein Products for HPS5:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005829 | cytosol |
IEA | -- |
HPS5 for ontologies About GeneDecksing
HPS5 Antibody Products:
Assay Products for HPS5: |
Protein
Domains /
Families
for HPS5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
HPS5 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UPZ3ProtoNet protein and cluster: Q9UPZ3 UniProtKB/Swiss-Prot: HPS5_HUMAN, Q9UPZ3Similarity: Belongs to the HPS5 family |
Function
for HPS5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: HPS5_HUMAN, Q9UPZ3Function: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such asmelanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involvedin the regulation of general functions of integrins Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
-- | -- |
HPS5 for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for HPS5:
12 MGI mutant phenotypes (inferred from 9 alleles ) (MGI details for Hps5):
HPS5 for phenotypes About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HPS5 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HPS5 (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): HPS5 (NM_007216) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HPS5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HPS5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HPS5 |
|
Pathways & Interactions
for HPS5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HPS5
4 Interacting proteins for HPS5 (Q9UPZ33) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
HPS5 for ontologies About GeneDecksing
|
Drugs & Compounds
for HPS5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for HPS5
Search CenterWatch for drugs/clinical trials and news about HPS5
|
Transcripts
for HPS5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for HPS5 gene (3 alternative transcripts): NM_007216.3 NM_181507.1 NM_181508.1 Unigene Cluster for HPS5: Hermansky-Pudlak syndrome 5 Hs.437599 [show with all ESTs]Unigene Representative Sequence: NM_18150711 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000396253(uc001mod.1 uc001moe.1 uc001mof.1) ENST00000349215
ENST00000438420 ENST00000537258 ENST00000352460 ENST00000545561 ENST00000544218
ENST00000543728 ENST00000531848 ENST00000399287(uc001mog.1) ENST00000589545
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HPS5 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HPS5 (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): HPS5 (NM_007216) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HPS5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HPS5 |
Additional cDNA sequence: AB023234.1 AF534400.1 AF534401.1 AF534402.1 AJ131721.1 AK024320.1 AK291663.1 AK292436.1 BC033640.1 14 DOTS entries: DT.100783194 DT.100783196 DT.40222882 DT.120739187 DT.92014828 DT.120739175 DT.120739178 DT.120739192 DT.40268427 DT.92428241 DT.120739108 DT.40289643 DT.455689 DT.99953278 24/144 AceView cDNA sequences (see all 144): AA886415 AI284160 BU197387 AA213555 AK024320 NM_181508 CD516199 AA465657 AW769857 BU160716 BI862374 CR626720 BQ212690 BU156385 AI016257 BM701876 CA449900 BM763537 AI091638 NM_007216 AL583178 AF534401 CF138588 AI635671
GeneLoc Exon Structure
5/18 Alternative Splicing Database (ASD) splice patterns (SP) for HPS5 (see all 18) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | · | 1f | · | 1g | · | 1h | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b | · | 8c | · | 8d | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | - | | - | | - | | - | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | - | | - | | - | | | | | | - | | - | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | |
| ExUns: | 8e | · | 8f | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18a | · | 18b | ^ | 19 | ^ | 20a | · | 20b | · | 20c | ^ | 21a | · | 21b | · | 21c | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25 | ^ | 26a | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for HPS5
|
Expression
for HPS5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| HPS5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See HPS5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for HPS5
SOURCE GeneReport for Unigene cluster: Hs.437599
UniProtKB/Swiss-Prot: HPS5_HUMAN, Q9UPZ3Tissue specificity: Widely expressed. Isoform 1:Highly expressed in lungs and testis. Isoform 2:Highly expressed inplacenta, kidney, testis ovary, lung and thymus
SABiosciences Custom PCR Arrays for HPS5
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HPS5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat HPS5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HPS5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HPS5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HPS5 |
Orthologs
for HPS5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for HPS5 gene from 5/15 species (see all 15) About this table
ENSEMBL Gene Tree for HPS5 (if available)
TreeFam Gene Tree for HPS5 (if available) |
Paralogs
for HPS5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for HPS5 gene
- TECPR22
1 SIMAP similar gene for HPS5 using alignment to 4 protein entries: HPS5_HUMAN (see all proteins):HGRHSV1
HPS5 for paralogs About GeneDecksing
|
Genomic Variants
for HPS5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for HPS5 (18300217 - 18343745 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for HPS5: --
Human Gene Mutation Database (HGMD): HPS5
Locus Specific Mutation Databases (LSDB): HPS5
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HPS5 |
|
Disorders
/ Diseases
for HPS5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
HPS5 for disorders About GeneDecksing
OMIM gene information: 607521
OMIM disorders: 203300
UniProtKB/Swiss-Prot: HPS5_HUMAN, Q9UPZ3
Defects in HPS5 are the cause of Hermansky-Pudlak syndrome type 5 (HPS5) [MIM:614074]. Hermansky-Pudlaksyndrome (HPS) is a genetically heterogeneous, rare, autosomal recessive disorder characterized by oculocutaneousalbinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects. This syndrome results fromdefects of diverse cytoplasmic organelles including melanosomes, platelet dense granules and lysosomes. Ceroid storagein the lungs is associated with pulmonary fibrosis, a common cause of premature death in individuals with HPS
9  diseases for HPS5: About MalaCardshermansky-pudlak syndrome hermansky-pudlak syndrome 5 hermansky-pudlak syndrome 6 hermansky-pudlak syndrome 3
platelet storage pool deficiency oculocutaneous albinism albinism pulmonary fibrosis
fibrosis
3 diseases from the University of Copenhagen DISEASES database for HPS5:Hermansky-Pudlak syndrome Oculocutaneous albinism Platelet storage pool deficiency 1 Novoseek disease relationship for HPS5 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| hermansky-pudlak syndrome |
93.9 |
1 |
15030569 (1) |
GeneTests: HPS5
Hermansky-Pudlak Syndrome
Human Genome Epidemiology (HuGE) Navigator: HPS5 (1 document)
Export disorders for HPS5 gene to outside databases
|
Publications
for HPS5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for HPS5 gene, integrated from 9 sources (see all 25):
(articles sorted by number of sources associating them with HPS5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)1, 2, 3 Nagase T.... Ohara O. (1999)
- Identification of novel interaction partners for the conserved membrane proximal region of alpha-integrin cytoplasmic domains. (PubMed id 10094488)1, 2, 3 Wixler V.... Aumailley M. (1999)
- Improper trafficking of melanocyte-specific proteins in Hermansky-Pudlak syndrome type-5. (PubMed id 17301833)1, 2, 9 Helip-Wooley A....Gahl W.A. (2007)
- Characterization of BLOC-2, a complex containing the Hermansky-Pudlak syndrome proteins HPS3, HPS5 and HPS6. (PubMed id 15030569)1, 2, 9 Di Pietro S.M....Dell'Angelica E.C. (2004)
- Cellular, molecular and clinical characterization of patients with Hermansky-Pudlak syndrome type 5. (PubMed id 15296495)1, 2, 9 Huizing M.... Gahl W.A. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Ru2 and Ru encode mouse orthologs of the genes mutated in human Hermansky-Pudlak syndrome types 5 and 6. (PubMed id 12548288)1, 2 Zhang Q.... Swank R.T. (2003)
- Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
|
External Searches for HPS5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing HPS5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing HPS5 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing HPS5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for HPS5 | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/HPS5 |
|
| | |
About This Section
| Patent Information for HPS5 gene:
Search GeneIP for patents involving HPS5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for HPS5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for HPS5 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HPS5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HPS5 | | | OriGene Protein Over-expression Lysate for HPS5 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for HPS5 | | OriGene 3'-UTR Clone for HPS5 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HPS5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HPS5 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for HPS5 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for HPS5 | | OriGene Custom Protein Services for HPS5 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HPS5 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HPS5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HPS5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HPS5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HPS5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HPS5 |
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| | | | Search Tocris compounds for HPS5 |
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 | | | HPS5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HPS5 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for HPS5 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HPS5 |
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