HPN Gene
protein-coding GIFtS: 63
GCID: GC19P035531
|
|
hepsin
| |
Aliases
for HPN gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Hepsin1 | | TMPRSS11 2 3 | | Transmembrane Protease Serine 12 3 | | EC 3.4.21.1063 8 | | Serine Protease Hepsin2 | | EC 3.4.218 |
Export aliases for HPN gene to outside databasesPrevious GC identifers: GC19P036148 GC19P035980 GC19P040207 GC19P040223 GC19P032039 |
Summaries
for HPN gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for HPN:
This gene encodes a type II transmembrane serine protease that may be involved in diverse cellular functions, includingblood coagulation and the maintenance of cell morphology. Expression of the encoded protein is associated with thegrowth and progression of cancers, particularly prostate cancer. The protein is cleaved into a catalytic serineprotease chain and a non-catalytic scavenger receptor cysteine-rich chain, which associate via a single disulfidebond. Alternative splicing results in multiple transcript variants. (provided by RefSeq, Jan 2013)
UniProtKB/Swiss-Prot: HEPS_HUMAN, P05981Function: Plays an essential role in cell growth and maintenance of cell morphology. May mediate the activatingcleavage of HGF and MST1/HGFL
Gene Wiki entry for HPN
|
Genomic Views
for HPN gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the HPN gene promoter:
Spz1 Pax-5 AML1a POU3F1 Lmo2 Max CREB deltaCREB c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for HPN
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HPN |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q11-q13.2 Ensembl cytogenetic band: 19q13.12 HGNC cytogenetic band: 19q11-q13.2HPN Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P035531: view genomic region
(about GC identifiers)
Start:
|
35,531,410 bp from pter |
End:
|
35,557,477 bp from pter |
Size:
|
26,068 bases |
Orientation:
|
plus strand |
|
Proteins
for HPN gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: HEPS_HUMAN, P05981 (See
protein sequence)Recommended Name: Serine protease hepsin Size: 417 amino acids; 45011 Da
Subcellular location: Membrane; Single-pass type II membrane protein
5 PDB 3D structures from  and Proteopedia  for HPN:1O5E (3D)
1O5F (3D)
1P57 (3D)
1Z8G (3D)
3T2N (3D)
Secondary accessions: B2RDS4Explore the universe of human proteins at neXtProt for HPN: NX_P05981
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P05981
4/8 DME Specific Peptides for HPN (P05981) (see all 8)
HPN Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_002142.1 NP_892028.1
ENSEMBL proteins: ENSP00000262626 ENSP00000376060 ENSP00000442035
Human Recombinant Protein Products:
Gene Ontology (GO): 5/10 cellular component terms (GO ID links to tree view) (see all 10): About this table
HPN for ontologies About GeneDecksing
HPN Antibody Products:
Assay Products for HPN: |
Protein
Domains /
Families
for HPN gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
HPN for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry P05981ProtoNet protein and cluster: P05981 3 Blocks protein families: IPB001190 Speract/scavenger receptor IPB001254 Serine protease IPB001314 Chymotrypsin serine protease family (S1) signature
UniProtKB/Swiss-Prot: HEPS_HUMAN, P05981Similarity: Belongs to the peptidase S1 familySimilarity: Contains 1 peptidase S1 domainSimilarity: Contains 1 SRCR domain |
Function
for HPN gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: HEPS_HUMAN, P05981Function: Plays an essential role in cell growth and maintenance of cell morphology. May mediate the activatingcleavage of HGF and MST1/HGFLCatalytic activity: Cleavage after basic amino-acid residues, with Arg strongly preferred to Lys Genatlas biochemistry entry for HPN:hepsin,cell membrane associated serine protease,activating factor VII
Enzyme Numbers (IUBMB): EC 3.4.21.1061 2 EC 3.4.212
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HPN (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HPN (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): HPN (NM_002151) | |  | Sino Biological Human cDNA Clone for HPN | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HPN | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HPN |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HPN |
Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table
HPN for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Hpntm1Qwu for HPN
5 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Hpn):
HPN for phenotypes About GeneDecksing
|
Pathways & Interactions
for HPN gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for HPN
STRING Interaction
Network Preview (showing 5 interactants - click image to see more details)
5/6 Interacting proteins for HPN (P059813 ENSP000002626264) via UniProtKB, MINT, STRING, and/or I2D (see all 6)About this table
Gene Ontology (GO): 5/18 biological process terms (GO ID links to tree view) (see all 18): About this table
HPN for ontologies About GeneDecksing
|
Drugs & Compounds
for HPN gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
HPN for compounds About GeneDecksing
 Browse Tocris compounds for HPN
5 DrugBank Compounds for HPN About this table
4 Novoseek chemical compound relationships for HPN gene About this table
Search CenterWatch for drugs/clinical trials and news about HPN / HEPS
|
Transcripts
for HPN gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for HPN gene (2 alternative transcripts): NM_002151.2 NM_182983.2 Unigene Cluster for HPN: Hepsin Hs.182385 [show with all ESTs]Unigene Representative Sequence: AK1256703 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000262626(uc002nxr.2) ENST00000392226(uc002nxq.2 uc010xsh.1 uc002nxt.1)
ENST00000541345
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HPN (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HPN (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): HPN (NM_002151) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HPN | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HPN |
Additional cDNA sequence: AK091988.1 AK095160.1 AK125670.1 AK293622.1 AK315655.1 BC025716.1 EU644753.1 M18930.1 X07002.1 X07732.1 15 DOTS entries: DT.91760387 DT.100817702 DT.95179900 DT.101958126 DT.97841550 DT.101971861 DT.92067980 DT.91760385 DT.95111479 DT.95179906 DT.100649945 DT.305869 DT.40132709 DT.91760386 DT.95090067 24/108 AceView cDNA sequences (see all 108): AA693970 CR592189 AL558100 CR597177 AI826254 BM923538 AK091988 AW613055 NM_182983 H75950 BI764518 NM_002151 BM994658 BX422288 AV683777 AI685007 AV688861 BI836687 AV693135 CB162594 BI768246 AA335485 BM548649 BX406458
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for HPN (see all 8) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 |
|---|
|
| SP1: | | | | | | | | | - | | | | | | | | - | | | | - | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | - | | | | - | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | - | | | | - | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for HPN
|
Expression
for HPN gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| HPN expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAAATATTGT
About this image
See HPN Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for HPN
SOURCE GeneReport for Unigene cluster: Hs.182385
UniProtKB/Swiss-Prot: HEPS_HUMAN, P05981Tissue specificity: Present in most tissues, with the highest level in liver
SABiosciences Expression via Pathway-Focused PCR Arrays including HPN:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HPN
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat HPN | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HPN | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HPN | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HPN |
Orthologs
for HPN gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for HPN gene from 4/13 species (see all 13) About this table
ENSEMBL Gene Tree for HPN (if available)
TreeFam Gene Tree for HPN (if available) |
Paralogs
for HPN gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for HPN gene
- TMPRSS72 TMPRSS52 ST142 TMPRSS42 TMPRSS11D2 TMPRSS132 TMPRSS11E2 TMPRSS32
- TMPRSS11B2 TMPRSS22 TMPRSS92 TMPRSS152 TMPRSS11F2 TMPRSS11A2 TMPRSS62
18/84 SIMAP similar genes for HPN using alignment to 5 protein entries: HEPS_HUMAN (see all proteins)
(see all similar genes):DKFZp586F0824 PRSS1 F12 HP TMPRSS11A TMPRSS11F
KLKB1 TMPRSS3 CELA2A ELA2A DKFZp779M0222 CTRL
CTRB1 OVCH1 PRSS27 TMPRSS11B CELA2B CTRB2
HPN for paralogs About GeneDecksing
|
Genomic Variants
for HPN gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for HPN (35531410 - 35557477 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for HPN: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HPN |
|
Disorders
/ Diseases
for HPN gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
HPN for disorders About GeneDecksing
OMIM gene information: 142440
OMIM disorders: --
20/27  diseases for HPN (see all 27): About MalaCardsprostate cancer prostatitis cancer progression/metastasis short bowel syndrome
intracranial aneurysm vestibular neuronitis hearing loss prostate cancer, progression of
prostate cancer, progression and metastasis of hepatitis b renal cell carcinoma prostate adenocarcinoma
hepatocellular carcinoma papillary carcinoma ovarian cancer carcinoma
gout endometrial cancer adenocarcinoma cervical cancer
2 diseases from the University of Copenhagen DISEASES database for HPN:Prostate cancer Short bowel syndrome 10/14 Novoseek disease relationships for HPN gene (see all 14) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| prostate cancer |
70.7 |
63 |
16783571 (4), 14665873 (4), 18784072 (4), 17569629 (4) (see all 26) |
| benign prostatic hyperplasia |
50.5 |
2 |
14665873 (1), 15609297 (1) |
| prostatic adenocarcinoma |
47.3 |
2 |
19938013 (1), 18338334 (1) |
| cancer |
41 |
7 |
20015050 (1), 18338334 (1), 12023851 (1), 17569629 (1) (see all 7) |
| metastasis |
38.4 |
17 |
19938013 (2), 15324701 (2), 18852137 (2), 18784072 (2) (see all 10) |
| aggressiveness |
36.9 |
2 |
16783571 (1), 14665873 (1) |
| tumors |
26.2 |
40 |
18784072 (4), 19938013 (3), 16585186 (3), 9230195 (2) (see all 16) |
| ovarian carcinoma |
24.9 |
1 |
18383840 (1) |
| primary tumor |
24.9 |
3 |
19938013 (1), 12962630 (1), 16585186 (1) |
| carcinoma renal cell |
22.3 |
5 |
15538223 (2), 17309599 (2), 9569208 (1) |
Genetic Association Database (GAD): HPN
Human Genome Epidemiology (HuGE) Navigator: HPN (5 documents)
Export disorders for HPN gene to outside databases
|
Publications
for HPN gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for HPN gene, integrated from 9 sources (see all 112):
(articles sorted by number of sources associating them with HPN) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A novel trypsin-like serine protease (hepsin) with a putative transmembrane domain expressed by human liver and hepatoma cells. (PubMed id 2835076)1, 2, 3 Leytus S.P.... Davie E.W. (1988)
- Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers. (PubMed id 15839837)1, 2, 9 Herter S....Austin R.J. (2005)
- Hepsin, a cell membrane-associated protease. Characterization, tissue distribution, and gene localization. (PubMed id 1885621)1, 2, 9 Tsuji A.... Kurachi K. (1991)
- Analysis of candidate genes for prostate cancer. (PubMed id 15583422)1, 4, 9 Burmester J.K....Catalona W.J. (2004)
- Proteolytic activation of pro-macrophage-stimulating protein by hepsin. (PubMed id 21875933)1, 2 Ganesan R....Kirchhofer D. (2011)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth. (PubMed id 8346233)1, 2 Torres-Rosado A.... Kurachi K. (1993)
- Decreased expressions of hepsin in human hepatocellular carcinomas. (PubMed id 16911458)1, 9 Chen C.H....Sheu J.C. (2006)
- Hepsin activates prostasin and cleaves the extracellu lar domain of the epidermal growth factor receptor. (PubMed id 19911255)1, 9 Chen M....Chai K.X. (2010)
|
External Searches for HPN gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing HPN gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing HPN gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing HPN gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for HPN gene:
Search GeneIP for patents involving HPN
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for HPN gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for HPN | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HPN | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HPN | | | OriGene Protein Over-expression Lysate for HPN | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for HPN | | OriGene 3'-UTR Clone for HPN | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HPN | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HPN | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for HPN | | OriGene Custom Protein Services for HPN | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HPN | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HPN | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HPN | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HPN | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HPN | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HPN |
| |
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| | | | Search Tocris compounds for HPN |
| |  |  |  |  | | | | |
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 |
 |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HPN |
|  |  |  | | | | ThermoFisher Antibodies for HPN |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HPN |
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