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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HPCAL1 Gene

protein-coding   GIFtS: 61
GCID: GC02P010443

hippocalcin-like 1
 Explore 5 diseases affiliated with
HPCAL1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for HPCAL1    

Aliases
for HPCAL1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Hippocalcin-Like 11 2     Calcium-Binding Protein BDR-12 3
BDR11 2 3     Visinin-Like Protein 32 3
HLP21 2 3     Hippocalcin-Like Protein 12
VILIP-31 2 3     

External Ids:    HGNC: 51451   Entrez Gene: 32412   Ensembl: ENSG000001157567   OMIM: 6002075   UniProtKB: P372353   

Export aliases for HPCAL1 gene to outside databases

Previous GC identifers: GC02P010228 GC02P010494 GC02P010464 GC02P010393


Summaries
for HPCAL1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for HPCAL1:
The protein encoded by this gene is a member of neuron-specific calcium-binding proteins family found in the retina and
brain. It is highly similar to human hippocalcin protein and nearly identical to the rat and mouse hippocalcin like-1
proteins. It may be involved in the calcium-dependent regulation of rhodopsin phosphorylation and may be of relevance
for neuronal signalling in the central nervous system. Several alternatively spliced transcript variants encoding the
same protein have been found for this gene. (provided by RefSeq, Apr 2012)

UniProtKB/Swiss-Prot: HPCL1_HUMAN, P37235
Function: May be involved in the calcium-dependent regulation of rhodopsin phosphorylation

Gene Wiki entry for HPCAL1


Genomic Views
for HPCAL1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_005334.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HPCAL1 gene promoter:
         AP-2beta   HNF-4alpha2   Meis-1a   HNF-4alpha1   Meis-1   Meis-1b   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: HPCAL1 promoter sequence
   Search SABiosciences Chromatin IP Primers for HPCAL1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HPCAL1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p25.1   Ensembl cytogenetic band:  2p25.1   HGNC cytogenetic band: 2p25.1

HPCAL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HPCAL1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P010443:  view genomic region     (about GC identifiers)

Start:
 10,443,015 bp from pter      End:
 10,567,743 bp from pter
Size:
 124,729 bases      Orientation:
 plus strand

Proteins
for HPCAL1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: HPCL1_HUMAN, P37235 (See protein sequence)
Recommended Name: Hippocalcin-like protein 1  
Size: 193 amino acids; 22313 Da
Miscellaneous: Probably binds two or three calcium ions (By similarity)
Secondary accessions: Q969S5

Explore the universe of human proteins at neXtProt for HPCAL1: NX_P37235

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P37235

    • HPCAL1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (5 alternative transcripts): 
    NP_001245286.1  NP_001245287.1  NP_001245288.1  NP_002140.2  NP_602293.1  

    ENSEMBL proteins: 
     ENSP00000413689   ENSP00000310749   ENSP00000371184   ENSP00000416359   ENSP00000388856  

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    ProSpec Recombinant Protein for HPCAL1
    Uscn Proteins for HPCAL1


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    Protein Domains /
    Families
    for HPCAL1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HPCAL1 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR001125 Recoverin
     IPR011992 EF-hand-like_dom
     IPR002048 EF_hand_Ca-bd
     IPR018247 EF_Hand_1_Ca_BS

    Graphical View of Domain Structure for InterPro Entry P37235

    ProtoNet protein and cluster: P37235

    1 Blocks protein family: IPB001125 Recoverin family signature

    UniProtKB/Swiss-Prot: HPCL1_HUMAN, P37235
    Similarity: Belongs to the recoverin family
    Similarity: Contains 4 EF-hand domains


    Function
    for HPCAL1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: HPCL1_HUMAN, P37235
    Function: May be involved in the calcium-dependent regulation of rhodopsin phosphorylation

         Genatlas biochemistry entry for HPCAL1:
    calcium binding protein,hippocalcin-like,expressed in brain

    miRNA
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    hsa-miR-374c hsa-miR-655 hsa-miR-198 hsa-miR-586 hsa-miR-32* hsa-miR-412
    SwitchGear 3'UTR luciferase reporter plasmid: HPCAL1 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    Search LifeMap BioReagents cell lines for HPCAL1

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HPCAL1

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--
    GO:0005515protein binding ----


    HPCAL1 for ontologies           About GeneDecksing


    Animal Models:
         1 MGI phenotypic allele for Hpcal1 (no phenotypes)

    HPCAL1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for HPCAL1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Visual Cycle in Retinal Rods
    		Visual Cycle in Retinal Rods1.00

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for HPCAL1
        Visual Cycle in Retinal Rods


    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for HPCAL1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/18 Interacting proteins for HPCAL1 (P372352, 3 ENSP000003107494) via UniProtKB, MINT, STRING, and/or I2D (see all 18)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HMG20AQ9NP662, 3, ENSP000003368564MINT-68016 I2D: score=5 STRING: ENSP00000336856
    DTX2Q86UW92, 3, ENSP000003228854MINT-67483 I2D: score=4 STRING: ENSP00000322885
    ATXN1P542533, ENSP000002447694I2D: score=2 STRING: ENSP00000244769
    SLC34A1Q064953, ENSP000003214244I2D: score=1 STRING: ENSP00000321424
    IKBKGQ9Y6K93, ENSP000003586224I2D: score=1 STRING: ENSP00000358622
    About this table

    Drugs & Compounds
    for HPCAL1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    HPCAL1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HPCAL1

    1 HMDB Compound for HPCAL1    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    1 Novoseek chemical compound relationship for HPCAL1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    calcium 23.2 6 10683417 (2), 12614903 (1), 18989702 (1)

    Search CenterWatch for drugs/clinical trials and news about HPCAL1 / HPCL1 

    Transcripts
    for HPCAL1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for HPCAL1 gene (5 alternative transcripts): 
    NM_001258357.1  NM_001258358.1  NM_001258359.1  NM_002149.3  NM_134421.2  

    Unigene Cluster for HPCAL1:

    Hippocalcin-like 1
    Hs.580427  [show with all ESTs]
    Unigene Representative Sequence: CR749837
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000423674 ENST00000307845(uc002raj.3) ENST00000381765(uc002ral.3 uc010exf.3)
    ENST00000419810(uc010exe.3) ENST00000422133

    miRNA
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    6 QIAGEN miScript miRNA Assays for microRNAs that regulate HPCAL1:
    hsa-miR-374c hsa-miR-655 hsa-miR-198 hsa-miR-586 hsa-miR-32* hsa-miR-412
    SwitchGear 3'UTR luciferase reporter plasmid: HPCAL1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HPCAL1 (see all 7)
    OriGene shRNA RFP: HPCAL1
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HPCAL1
    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HPCAL1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HPCAL1

    Additional cDNA sequence: 

    AF070616.1 AK000596.1 AK093973.1 AK126732.1 AK292280.1 BC009846.2 BC017028.1 BC017482.1 
    BT009835.1 CR541975.1 CR749837.1 D16227.1 

    14 DOTS entries:

    DT.85105581  DT.100797295  DT.100043084  DT.95083302  DT.101972123  DT.95138632  DT.99956155  DT.100043042 
    DT.100720747  DT.102830058  DT.91775828  DT.97861204  DT.120956707  DT.91775820 

    24/315 AceView cDNA sequences (see all 315):

    BQ649273 AA346219 BU732101 BU789070 BM768954 CB530018 AA991312 BC017482 
    BX362119 AA902426 AA970853 AW673070 CR599816 CA419164 CR613842 AV728984 
    CR599915 BM462631 BQ083965 CD367290 CB122517 BQ926519 CR591594 CR593075 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for HPCAL1 (see all 9)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b · 13c · 13d
    SP1:                    -     -     -     -     -           -     -                             -                           
    SP2:              -     -     -     -     -     -           -     -                             -                           
    SP3:                                      -     -           -     -                             -                           
    SP4:                                                                                                                        
    SP5:              -     -     -     -     -     -                                                                           


    ECgene alternative splicing isoforms for HPCAL1

    Expression
    for HPCAL1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HPCAL1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TGTGCCCTGA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    HPCAL1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    EyeInner Nuclear LayerCholinergic Amacrine CellsAmacrine, Retina
    EyeOuter Nuclear LayerMature Rod CellsPhotoreceptors, Retina
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    PureStem™ progenitor E44 (Embryonic Progenitor Cell)

    See HPCAL1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HPCAL1

    SOURCE GeneReport for Unigene cluster: Hs.580427
        SABiosciences Custom PCR Arrays for HPCAL1
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    In Situ
    Assay Products:     
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    Orthologs
    for HPCAL1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for HPCAL1 gene from 3/20 species (see all 20)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves HPCAL11 hippocalcin-like 1 87.74(n)
    98.45(a)    		   396161  NM_205234.1  NP_990565.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc731262 hypothetical protein MGC73126 84.8(n)   393696  BC059489.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Nca1 , 3 negative regulation of phosphorylation
    calcium more3
    Neurocalcin1    		 89(a)
    (best of 4)3
    70.37(n)1
    89.42(a)1    		   3 76D83
    401861  NM_001170007.11  NP_001163478.11 


    ENSEMBL Gene Tree for HPCAL1 (if available)
    TreeFam Gene Tree for HPCAL1 (if available) 

    Paralogs
    for HPCAL1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HPCAL1 gene
    HPCA2  KCNIP32  KCNIP42  GUCA1A2  KCNIP12  RCVRN2  GUCA1B2  NCALD2  
    KCNIP22  HPCAL42  NCS12  VSNL12  GUCA1C2  
    18/23 SIMAP similar genes for HPCAL1 using alignment to 5 protein entries:     HPCL1_HUMAN (see all proteins) (see all similar genes):
    DKFZp781K1922    NCALD    HPCA    VSNL1    HPCAL4    NCS1
    RCV1    RCVRN    KCNIP4    KCNIP3    GUCA1A    KCNIP2
    KCNIP1    GUCA1B    DKFZp686E1183    EFCAB1    GUCA1C    PPP3R2

    HPCAL1 for paralogs           About GeneDecksing



    Genomic Variants
    for HPCAL1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2464 NCBI SNPs in HPCAL1 are shown (see all 2464)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 2 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1892216051,2
    		--10441094(+) GGGACG/TCAAGG 1 -- us2k10--------
    rs1926599901,2
    		--10441195(+) AGAGGA/TAGCAT 1 -- us2k10--------
    rs739140371,2
    		C,--10441419(+) CTCCTG/ACCTGT 1 -- us2k12Minor allele frequency- A:0.07WA 120
    rs1847926701,2
    		--10441465(+) ACAGAC/TTTTGC 1 -- us2k10--------
    rs1893077621,2
    		--10441565(+) TCCGAA/GACACT 1 -- us2k10--------
    rs1400074911,2
    		--10441623(+) GCGACA/TACTTC 1 -- us2k10--------
    rs1498654151,2
    		--10441636(+) GCCCAC/TGGATG 1 -- us2k10--------
    rs1438766491,2
    		--10441731(+) CCTGGA/GTACTT 1 -- us2k10--------
    rs727716631,2
    		C,F,--10441790(+) GGGTAC/TCGGGC 1 -- us2k11Minor allele frequency- T:0.07NA 120
    rs1163129851,2
    		F,--10441891(+) AGGTCT/CAGCTT 2 -- us2k11Minor allele frequency- C:0.05WA 118

    HapMap Linkage Disequilibrium report for HPCAL1 (10443015 - 10567743 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for HPCAL1
         2 CNVs: 72629 35704

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    Disorders / Diseases
    for HPCAL1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    HPCAL1 for disorders           About GeneDecksing

    OMIM gene information: 600207    OMIM disorders: --

    5 diseases for HPCAL1:    About MalaCards
    neuronitis    hypertension    alzheimer's disease    ataxia
    retinitis

    Genetic Association Database (GAD): HPCAL1
    Human Genome Epidemiology (HuGE) Navigator: HPCAL1 (2 documents)

    Export disorders for HPCAL1 gene to outside databases

    Publications
    for HPCAL1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HPCAL1 gene, integrated from 9 sources (see all 30):
    (articles sorted by number of sources associating them with HPCAL1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning of a novel calcium-binding protein structurally related to hippocalcin from human brain and chromosomal mapping of its gene. (PubMed id 8038222)1, 2, 3 Kobayashi M.... Noguchi T. (1994)
    2. Hypertension susceptibility genes on chromosome 2p24-p25 in a general Japanese population. (PubMed id 15834280)1, 4, 9 Kamide K....Miyata T. (2005)
    3. Neuronal calcium sensor protein visinin-like protein-3 interacts with microsomal cytochrome b5 in a Ca2+-dependent manner. (PubMed id 14739275)1, 3 Oikawa K....Tateno M. (2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. The neuronal EF-hand calcium-binding protein visinin-like protein-3 is expressed in cerebellar Purkinje cells and shows a calcium-dependent membrane association. (PubMed id 10683417)1, 9 Spilker C....Braunewell K.H. (2000)
    6. Regional and cellular distribution of neural visinin-like protein immunoreactivities (VILIP-1 and VILIP-3) in human brain. (PubMed id 10851344)1, 9 Bernstein H.G....Braunewell K.H. (1999)
    7. Functional contribution of Ca2+ and Mg2+ to the intermolecular interaction of visinin-like proteins. (PubMed id 16703469)1, 9 Jheng F.F....Chang L.S. (2006)
    8. Abnormal localization of two neuronal calcium sensor proteins, visinin-like proteins (vilips)-1 and -3, in neocortical brain areas of Alzheimer disease patients. (PubMed id 11173883)1, 9 Braunewell K....Bernstein H.G. (2001)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

    External Searches for HPCAL1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Genome Databases showing HPCAL1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 3241 HGNC: 5145 AceView: HPCAL1 Ensembl:ENSG00000115756 euGenes: HUgn3241
    ECgene: HPCAL1 H-InvDB: HPCAL1

    Other Databases showing HPCAL1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing HPCAL1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HPCAL1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for HPCAL1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for HPCAL1 gene:
    Search GeneIP for patents involving HPCAL1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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