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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HOXD3 Gene

protein-coding   GIFtS: 52
GCID: GC02P177001

homeobox D3

(Previous name: homeo box D3 )
(Previous symbols: HOX4A, HOX4, HOX1D)
 Explore 13 diseases affiliated with
HOXD3 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for HOXD3    

Aliases
for HOXD3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Homeobox D31 2     Homeobox Protein Hox-4A2 3
HOX4A1 2 3 5     Hox-4.12
HOX1D1 2 3     Homeobox Protein Hox-D32
HOX41 2     Hox-4.1, Mouse, Homolog Of2
Homeo Box D31 2     

External Ids:    HGNC: 51371   Entrez Gene: 32322   Ensembl: ENSG000001286527   OMIM: 1429805   UniProtKB: P312493   

Export aliases for HOXD3 gene to outside databases

Previous GC identifers: GC02P175081 GC02P175689 GC02P176992 GC02P177231 GC02P176854 GC02P176737 GC02P168905


Summaries
for HOXD3 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for HOXD3:
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription
factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar
homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes
arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions
that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital
abnormalities. The protein encoded by this gene may play a role in the regulation of cell adhesion processes.
(provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: HXD3_HUMAN, P31249
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells
with specific positional identities on the anterior-posterior axis

Gene Wiki entry for HOXD3


Genomic Views
for HOXD3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_005403.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HOXD3 gene promoter:
         E2F-4   E2F-3a   E2F-5   E2F-2   c-Ets-1   E2F   E2F-1   COMP1   HOXA5   FOXO1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: HOXD3 promoter sequence
   Search SABiosciences Chromatin IP Primers for HOXD3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HOXD3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q31.1   Ensembl cytogenetic band:  2q31.1   HGNC cytogenetic band: 2q31.1

HOXD3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HOXD3 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P177001:  view genomic region     (about GC identifiers)

Start:
 177,001,340 bp from pter      End:
 177,039,577 bp from pter
Size:
 38,238 bases      Orientation:
 plus strand

Proteins
for HOXD3 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: HXD3_HUMAN, P31249 (See protein sequence)
Recommended Name: Homeobox protein Hox-D3  
Size: 432 amino acids; 45730 Da
Subcellular location: Nucleus
Caution: It is uncertain whether Met-1 or Met-17 is the initiator
Sequence caution: Sequence=BAA01891.1; Type=Erroneous initiation;
Secondary accessions: Q99955 Q9BSC5

Explore the universe of human proteins at neXtProt for HOXD3: NX_P31249

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P31249

    • HOXD3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_008829.3  
    ENSEMBL proteins: 
     ENSP00000392615   ENSP00000424734   ENSP00000386498   ENSP00000249440  

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    Uscn Proteins for HOXD3

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IC12836255


    HOXD3 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for HOXD3 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HOXD3 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR001827 Homeobox_Antennapedia_CS
     IPR020479 Homeobox_metazoa
     IPR017970 Homeobox_CS
     IPR001356 Homeodomain
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry P31249

    ProtoNet protein and cluster: P31249

    2 Blocks protein families:
    IPB000047 Lambda and other repressor helix-turn-helix signature
    IPB001827 Homeobox protein


    UniProtKB/Swiss-Prot: HXD3_HUMAN, P31249
    Similarity: Belongs to the Antp homeobox family
    Similarity: Contains 1 homeobox DNA-binding domain


    Function
    for HOXD3 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: HXD3_HUMAN, P31249
    Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells
    with specific positional identities on the anterior-posterior axis

         Genatlas biochemistry entry for HOXD3:
    homeo box D3(4A),homologous to mouse Hox-4.1,Drosophila Zen

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HOXD3
    8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate HOXD3 (see all 9):
    hsa-miR-21* hsa-miR-3671 hsa-miR-1226 hsa-miR-1283 hsa-miR-548o hsa-miR-500a hsa-miR-606 hsa-miR-466
    SwitchGear 3'UTR luciferase reporter plasmid: HOXD3 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: HOXD3
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0005515protein binding IPI--
    GO:0043565sequence-specific DNA binding IEA--


    HOXD3 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for HOXD3:
     Decreased Wnt reporter activit 

    Animal Models:
         Mouse knock-outs for HOXD3: Hoxd3tm2Mrc Hoxd3tm1Mrc
         11 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Hoxd3):
     cardiovascular system  cellular  craniofacial  embryogenesis  endocrine/exocrine gland 
     hematopoietic system  immune system  mortality/aging  nervous system  respiratory system 
     skeleton 

    HOXD3 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for HOXD3 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for HOXD3

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    5/9 Interacting proteins for HOXD3 (P312491, 3 ENSP000002494404) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ALX4Q9H1613, ENSP000003327444I2D: score=1 STRING: ENSP00000332744
    HMGB1P094293, ENSP000003430404I2D: score=1 STRING: ENSP00000343040
    DDB1Q165313, ENSP000003017644I2D: score=1 STRING: ENSP00000301764
    CERS2Q96G233I2D: score=1 
    CSDE1O755343I2D: score=1 
    About this table

    Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IMP12836255
    GO:0007160cell-matrix adhesion IDA7742539
    GO:0007219Notch signaling pathway IMP12836255
    GO:0009952anterior/posterior pattern specification ISS--
    GO:0010628positive regulation of gene expression IMP12836255


    HOXD3 for ontologies           About GeneDecksing



    Drugs & Compounds
    for HOXD3 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HOXD3
    Search CenterWatch for drugs/clinical trials and news about HOXD3 / HXD3 

    Transcripts
    for HOXD3 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for HOXD3 gene: 
    NM_006898.4  

    Unigene Cluster for HOXD3:

    Homeobox D3
    Hs.93574  [show with all ESTs]
    Unigene Representative Sequence: BC005124
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000459979(uc002ukr.3) ENST00000432796 ENST00000468418 ENST00000410016
    ENST00000249440(uc002ukt.1)

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    hsa-miR-21* hsa-miR-3671 hsa-miR-1226 hsa-miR-1283 hsa-miR-548o hsa-miR-500a hsa-miR-606 hsa-miR-466
    SwitchGear 3'UTR luciferase reporter plasmid: HOXD3 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HOXD3 (see all 4)
    OriGene shRNA RFP: HOXD3
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    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HOXD3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HOXD3

    Additional cDNA sequence: 

    BC005124.2 BC008789.2 

    2 DOTS entries:

    DT.75105776  DT.99968895 

    24/28 AceView cDNA sequences (see all 28):

    BF739816 AI373293 NM_006898 BF114998 AW300138 AW137579 BC005124 AI911593 
    BC047605 AI769665 AI373320 BE348261 AI955470 BE463473 BC008789 AI478225 
    AI927335 AW138896 AI223210 AW271503 BE797724 BM543946 AI521702 AA434183 

    GeneLoc Exon Structure


    Expression
    for HOXD3 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HOXD3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGTAGAGTCA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    HOXD3 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    5 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    SomiteCervical Mesenchymal SclerotomeCervical Sclerotome CellsBone, Cartilage, Tendons & Ligaments
    Head MesenchymeBranchial Arch 3,4,6Cardiac Neural Crest CellsNeural Crest
    Lateral Plate MesodermProepicardiumAngioblastsEndothelium
    Gut TubeMidgutMidgut Endoderm CellsEndoderm
    Gut TubeMidgutGut Tube
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Primordial-like germ cells (cKIT+ SSEA1+ VASA+) (Derivation of primor...)

    See HOXD3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HOXD3

    SOURCE GeneReport for Unigene cluster: Hs.93574
        SABiosciences Expression via Pathway-Focused PCR Array including HOXD3: 
              Homeobox (HOX) Genes in human mouse rat

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    In Situ
    Assay Products:     
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    Orthologs
    for HOXD3 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for HOXD3 gene from 3/15 species (see all 15)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves HOXD31 homeobox D3 77.91(n)
    79.61(a)    		   431212  XM_428765.3  XP_428765.2 
    lizard
    (Anolis carolinensis)    		 Reptilia HOXD36
    		 --
    		 70(a)
    		 1 ↔ 1
    		 GL343356.1(402731-409310)
    zebrafish
    (Danio rerio)    		 Actinopterygii hoxd3a1 homeo box D3a 66.58(n)
    70.38(a)    		   30349  NM_131125.1  NP_571200.1 


    ENSEMBL Gene Tree for HOXD3 (if available)
    TreeFam Gene Tree for HOXD3 (if available) 

    Paralogs
    for HOXD3 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HOXD3 gene
    GSX12  HOXA72  HOXA12  HOXD12  HOXA22  HOXB32  HOXC62  HOXB52  
    GSX22  HOXC52  HOXB42  HOXA52  HOXA42  HOXA62  HOXC82  HOXA32  
    HOXD82  HOXB12  HOXB62  HOXB82  HOXD42  HOXB22  HOXB72  PDX12  
    HOXC42  
    5 SIMAP similar genes for HOXD3 using alignment to 3 protein entries:     HXD3_HUMAN (see all proteins):
    HOXA3    HOXB3    HOXD8    HOXB6    DLX6

    HOXD3 for paralogs           About GeneDecksing



    Genomic Variants
    for HOXD3 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/181 NCBI SNPs in HOXD3 are shown (see all 181)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 2 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1453307141,2
    		--177026810(+) GGTTGC/GGACAG 1 -- us2k10--------
    rs1852212371,2
    		--177026837(+) AACCGA/CCTTCC 1 -- us2k10--------
    rs1905463711,2
    		--177026933(+) ATTTTC/TCTTTG 1 -- us2k10--------
    rs1141187991,2
    		--177027022(+) ATGGAA/GCATTC 1 -- us2k10--------
    rs1823744731,2
    		--177027049(+) GAAAAC/TTTCAA 1 -- us2k10--------
    rs1476726231,2
    		--177027065(+) CCTACC/TAAGGC 1 -- us2k10--------
    rs347204561,2
    		C,F,--177027292(+) GACCCG/ACGTGG 1 -- us2k16Minor allele frequency- A:0.19NA CSA WA EA 366
    rs126200321,2
    		C,H--177027833(+) GCCCTA/TCCGGG 1 -- us2k10--------
    rs1501756981,2
    		--177027931(+) GGCTGC/TGCGCT 1 -- us2k10--------
    rs75918201,2
    		C,A,H,--177028144(+) GGAAAT/GGATGT 1 -- us2k17Minor allele frequency- G:0.28NS EA CSA WA NA 634

    HapMap Linkage Disequilibrium report for HOXD3 (177001340 - 177039577 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for HOXD3: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HOXD3
    DNA2.0 Custom Variant and Variant Library Synthesis for HOXD3

    Disorders / Diseases
    for HOXD3 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    HOXD3 for disorders           About GeneDecksing

    OMIM gene information: 142980    OMIM disorders: --

    13 diseases for HOXD3:    About MalaCards
    duane retraction syndrome    vacterl association    esophageal atresia    clubfoot
    prostate cancer, progression of    prostate cancer    ovarian cancer    prostatitis
    cerebritis    esophagitis    thyroiditis    melanoma
    neuronitis

    1 disease from the University of Copenhagen DISEASES database for HOXD3:
    VACTERL association
    Human Genome Epidemiology (HuGE) Navigator: HOXD3 (3 documents)

    Export disorders for HOXD3 gene to outside databases

    Publications
    for HOXD3 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HOXD3 gene, integrated from 9 sources (see all 33):
    (articles sorted by number of sources associating them with HOXD3)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Vertebrate homeobox gene nomenclature. (PubMed id 1358459)1, 3 Scott M.P. (1992)
    3. Cloning and sequencing of the human homeobox gene HOX4A. (PubMed id 1358204)1, 2 Taniguchi Y.... Moriuchi T. (1992)
    4. Nomenclature for human homeobox genes. (PubMed id 1973146)1, 3 McAlpine P.J. and Shows T.B. (1990)
    5. Organization of human class I homeobox genes. (PubMed id 2576652)1, 2 Boncinelli E.... Simeone A. (1989)
    6. Overexpression of the HOX4A (HOXD3) homeobox gene in human erythroleukemia HEL cells results in altered adhesive properties. (PubMed id 7742539)1, 9 Taniguchi Y....Moriuchi T. (1995)
    7. Association of tissue promoter methylation levels of APC, TGFI^2, HOXD3 and RASSF1A with prostate cancer progression. (PubMed id 21207416)1 Liu L....Bapat B. (2011)
    8. A genome-wide association study identifies susceptibi lity loci for ovarian cancer at 2q31 and 8q24. (PubMed id 20852632)1 Goode E.L....Pharoah P.D. (2010)
    9. An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (2010)
    10. DNA methylation of HOXD3 as a marker of prostate canc er progression. (PubMed id 20212450)1 Kron K.J....Bapat B. (2010)

    External Searches for HOXD3 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing HOXD3 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 3232 HGNC: 5137 AceView: HOXD3 Ensembl:ENSG00000128652 euGenes: HUgn3232
    ECgene: HOXD3 H-InvDB: HOXD3

    Other Databases showing HOXD3 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing HOXD3 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HOXD3 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for HOXD3 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for HOXD3 gene:
    Search GeneIP for patents involving HOXD3

    GeneCards and IP:
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