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HOXD12 Gene

protein-coding   GIFtS: 51
GCID: GC02P176930

Homeobox D12

(Previous name: homeo box D12)
(Previous symbol: HOX4H)
  See HOXD12-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Homeobox D121 2
HOX4H1 2 3 5
Homeo Box D121 2
Homeobox Protein Hox-4H2 3
Homeobox Protein Hox-D122
Hox-4.7, Mouse, Homolog Of2

External Ids:    HGNC: 51351   Entrez Gene: 32382   Ensembl: ENSG000001701787   OMIM: 1429885   UniProtKB: P354523   

Export aliases for HOXD12 gene to outside databases

Previous GC identifers: GC02P175017 GC02P175625 GC02P177168 GC02P177169 GC02P176790 GC02P176672 GC02P168842


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for HOXD12 Gene:
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of
transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals
possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes,
consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a
cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have
been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined.
(provided by RefSeq, Jul 2008)

GeneCards Summary for HOXD12 Gene:
HOXD12 (homeobox D12) is a protein-coding gene. Diseases associated with HOXD12 include brachydactyly-syndactyly syndrome, and talipes equinovarus. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is HOXD11.

UniProtKB/Swiss-Prot: HXD12_HUMAN, P35452
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides
cells with specific positional identities on the anterior-posterior axis

Gene Wiki entry for HOXD12 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NC_018913.2  NT_005403.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the HOXD12 gene promoter:
         TBP   PPAR-gamma1   E2F   E2F-2   PPAR-gamma2   c-Ets-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHOXD12 promoter sequence
   Search Chromatin IP Primers for HOXD12

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HOXD12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q31.1   Ensembl cytogenetic band:  2q31.1   HGNC cytogenetic band: 2q31.1

HOXD12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HOXD12 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P176930:  view genomic region     (about GC identifiers)

Start:
176,964,458 bp from pter      End:
176,966,408 bp from pter
Size:
1,951 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: HXD12_HUMAN, P35452 (See protein sequence)
Recommended Name: Homeobox protein Hox-D12  
Size: 270 amino acids; 29031 Da
Secondary accessions: B5MCP0 Q9NS03

Explore the universe of human proteins at neXtProt for HOXD12: NX_P35452

Explore proteomics data for HOXD12 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See HOXD12 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_067016.3  
    ENSEMBL proteins: 
     ENSP00000385586   ENSP00000385132  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    HOXL: Homeoboxes / ANTP class : HOXL subclass

    4 InterPro protein domains:
     IPR020479 Homeobox_metazoa
     IPR017970 Homeobox_CS
     IPR001356 Homeobox_dom
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry P35452

    ProtoNet protein and cluster: P35452

    1 Blocks protein domain: IPB000047 Lambda and other repressor helix-turn-helix signature

    UniProtKB/Swiss-Prot: HXD12_HUMAN, P35452
    Similarity: Belongs to the Abd-B homeobox family
    Similarity: Contains 1 homeobox DNA-binding domain


    Find genes that share domains with HOXD12           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HXD12_HUMAN, P35452
    Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides
    cells with specific positional identities on the anterior-posterior axis

         Genatlas biochemistry entry for HOXD12:
    homeo box D12(4H),homologous to mouse Hox-4.7,interacting with HOD13 during mouse limb development

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0005515protein binding ----
    GO:0043565sequence-specific DNA binding IEA--
         
    Find genes that share ontologies with HOXD12           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for HOXD12:
     Decreased Wnt reporter activit 

         8 MGI mutant phenotypes (inferred from 4 alleles(MGI details for Hoxd12):
     digestive/alimentary  embryogenesis  limbs/digits/tail  mortality/aging  muscle 
     nervous system  reproductive system  skeleton 

    Find genes that share phenotypes with HOXD12           About GenesLikeMe

    Animal Models:
         MGI mouse knock-outs for HOXD12: Evx2/Hoxd11/Hoxd12/Hoxd13Evx2/Hoxd11/Hoxd12/tm1Ddu Hoxd12tm1Mrc

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HOXD12
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    HXD12_HUMAN, P35452: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000228nuclear chromosome ----
    GO:0005634nucleus IEA--
    GO:0005667transcription factor complex IEA--

    Find genes that share ontologies with HOXD12           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including HOXD12: 
              Homeobox (HOX) Genes in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for HOXD12

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    Selected Interacting proteins for HOXD12 (P354523 ENSP000003855864) via UniProtKB, MINT, STRING, and/or I2D (see all 18)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAFGO155253, ENSP000003503694I2D: score=2 STRING: ENSP00000350369
    MEIS1O004703, ENSP000002723694I2D: score=2 STRING: ENSP00000272369
    ALX4Q9H1613, ENSP000003327444I2D: score=1 STRING: ENSP00000332744
    MAFO754443, ENSP000003270484I2D: score=1 STRING: ENSP00000327048
    MAFBQ9Y5Q33, ENSP000003624104I2D: score=1 STRING: ENSP00000362410
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    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001501skeletal system development IEA--
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated ----
    GO:0007275multicellular organismal development ----
    GO:0007389pattern specification process IEA--

    Find genes that share ontologies with HOXD12           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HOXD12 (HXD12)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for HOXD12 gene: 
    NM_021193.3  

    Unigene Cluster for HOXD12:

    Homeobox D12
    Hs.450028  [show with all ESTs]
    Unigene Representative Sequence: BC121103
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000406506(uc010zev.1) ENST00000404162
    miRNA
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      QuantiTect SYBR Green Assays in human, mouse, rat HOXD12
      Search QuantiFast Probe-based Assays in human, mouse, rat HOXD12

    Additional mRNA sequence: 

    BC069088.1 BC121103.1 BC121104.1 

    3 DOTS entries:

    DT.120958985  DT.91684853  DT.95086599 

    3 AceView cDNA sequences:

    BC069088 NM_021193 BG031716 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HOXD12 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACAGTGCAGG
    HOXD12 Expression
    About this image


    HOXD12 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Limb (Muscoskeletal System)    fully expand to see all 3 entries
             Prechondrocytic Mesenchymal Cells Autopod
     
     Mesoderm (Gastrulation Derivatives)    fully expand to see all 2 entries
             Limb Bud Mesenchyme Cells Limb Bud
     
     Bone (Muscoskeletal System)
             Prechondrocytic Mesenchymal Cells Autopod
     
     Cartilage (Muscoskeletal System)
             Prechondrocytic Mesenchymal Cells Autopod
     
     Kidney (Urinary System)
             Metanephric Mesenchyme Cells Metanephric Mesenchyme
    HOXD12 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HOXD12 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.450028
        Pathway & Disease-focused RT2 Profiler PCR Array including HOXD12: 
              Homeobox (HOX) Genes in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for HOXD12 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hoxd121 , 5 homeobox D121, 5 84.58(n)1
    85.07(a)1
      2 (44.13 cM)5
    154321  NM_008274.31  NP_032300.21 
     746749295 
    chicken
    (Gallus gallus)
    Aves HOXD121 homeobox D12 65.29(n)
    64.66(a)
      396178  NM_205249.1  NP_990580.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    85(a)
    many ↔ many
    GL343356.1(570379-570618)
    zebrafish
    (Danio rerio)
    Actinopterygii hoxd12a1 homeo box D12a 54.65(n)
    46.12(a)
      100006598  NM_001126486.1  NP_001119958.1 


    ENSEMBL Gene Tree for HOXD12 (if available)
    TreeFam Gene Tree for HOXD12 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HOXD12 gene
    HOXD112  ENSG000002571842  HOXD102  HOXC132  HOXC102  HOXA92  HOXA132  HOXC92  
    HOXB132  HOXC122  HOXC112  HOXD132  HOXA112  HOXB92  HOXD92  HOXA102  
    8 SIMAP similar genes for HOXD12 using alignment to 4 protein entries:     HXD12_HUMAN (see all proteins):
    HOXC13    HOX B6    HOXA4    HOXB1    NKX2-5    HOXC12
    POU6F1    HOXD8

    Find genes that share paralogs with HOXD12           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HOXD12 (see all 95)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1830213611,2
    --176962553(+) TGTTCA/CATTCT 1 -- us2k10--------
    rs8471561,2
    C,F,A--176962561(+) TCTCTT/CAATCA 1 -- us2k112Minor allele frequency- C:0.35MN NA WA CSA EA 556
    rs8471551,2
    C,F--176962580(+) GCCACT/CCTCCC 1 -- us2k112Minor allele frequency- C:0.29MN NA WA CSA EA 556
    rs743586961,2
    C,F--176962648(+) TTGCCT/CGCCAG 1 -- us2k11Minor allele frequency- C:0.03EA 120
    rs1166406051,2
    C,F--176962695(+) AGACTG/ATCCAA 1 -- us2k11Minor allele frequency- A:0.07WA 118
    rs1868685191,2
    --176962771(+) TAGTCC/TTGAGG 1 -- us2k10--------
    rs1431674791,2
    C--176962868(+) CGTGA-/GGA   
      GAGACT
    GCAGG
    1 -- us2k10--------
    rs75730071,2
    C,F--176962873(+) GGAGAT/GACTGC 1 -- us2k11Minor allele frequency- G:0.00CSA 1
    rs8471541,2
    C,F,A--176962958(-) AAGAGC/TTCTTA 1 -- us2k111Minor allele frequency- T:0.31NA WA CSA EA 372
    rs8471531,2
    C,F,A,H--176962989(-) ATACTC/TAAGGG 1 -- us2k123Minor allele frequency- T:0.35NS EA NA WA CSA 2346

    HapMap Linkage Disequilibrium report for HOXD12 (176964458 - 176966408 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for HOXD12 (see all 13):    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv520227CNV Loss19592680
    nsv875441CNV Loss21882294
    nsv875447CNV Loss21882294
    nsv875442CNV Loss21882294
    dgv4368n71CNV Loss21882294
    nsv524250CNV Loss19592680
    nsv875438CNV Loss21882294
    nsv875446CNV Loss21882294
    nsv875437CNV Loss21882294
    dgv4369n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing HOXD12
    DNA2.0 Custom Variant and Variant Library Synthesis for HOXD12

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 142988    OMIM disorders: --

    2 diseases for HOXD12:    
    About MalaCards
    brachydactyly-syndactyly syndrome    talipes equinovarus

    2 diseases from the University of Copenhagen DISEASES database for HOXD12:
    Polydactyly     Syndactyly

    Find genes that share disorders with HOXD12           About GenesLikeMe

    Genetic Association Database (GAD): HOXD12
    Human Genome Epidemiology (HuGE) Navigator: HOXD12 (5 documents)

    Export disorders for HOXD12 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HOXD12 gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with HOXD12)
        Utopia: connect your pdf to the dynamic
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    1. EVX2, a human homeobox gene homologous to the even-skipped segmentation gene, is localized at the 5' end of HOX4 locus on chromosome 2. (PubMed id 1675198)1, 2, 3 D'Esposito M....Boncinelli E. (Genomics 1991)
    2. Study of HOXD genes in autism particularly regarding the ratio of second to fourth digit length. (PubMed id 19540081)1, 4 Sugie Y....Osawa J. (amp 2010)
    3. Altered transmission of HOX and apoptotic SNPs identify a potential common pathway for clubfoot. (PubMed id 19938081)1, 4 Ester A.R....Hecht J.T. (Am. J. Med. Genet. A 2009)
    4. High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. (PubMed id 19453261)1, 4 Yerges L.M....Zmuda J.M. (J. Bone Miner. Res. 2009)
    5. [Analysis of association between 5' HOXD gene and idiopathic congenital talipes equinovarus]. (PubMed id 16331564)1, 4 Wang L.L....Sun K.L. (Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2005)
    6. Nomenclature for human homeobox genes. (PubMed id 1973146)1, 3 McAlpine P.J. and Shows T.B. (Genomics 1990)
    7. A region of the human HOXD cluster that confers polycomb-group responsiveness. (PubMed id 20085705)1 Woo C.J....Kingston R.E. (Cell 2010)
    8. Mutations in HOXD13 underlie syndactyly type V and a novel brachydactyly-syndactyly syndrome. (PubMed id 17236141)1 Zhao X.... Zhang X. (Am. J. Hum. Genet. 2007)
    9. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W.... Wilson R.K. (Nature 2005)
    10. Complete mutation analysis panel of the 39 human HOX genes. (PubMed id 11857506)1 Kosaki K.... Matsuo N. (Teratology 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 3238 HGNC: 5135 AceView: HOXD12 Ensembl:ENSG00000170178 euGenes: HUgn3238
    ECgene: HOXD12 H-InvDB: HOXD12

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HOXD12 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for HOXD12 gene:
    Search GeneIP for patents involving HOXD12

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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