Aliases for HOXD1 Gene
External Ids for HOXD1 Gene
Previous HGNC Symbols for HOXD1 Gene
Previous GeneCards Identifiers for HOXD1 Gene
This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. This nuclear protein functions as a sequence-specific transcription factor that is involved in differentiation and limb development. Mutations in this gene have been associated with severe developmental defects on the anterior-posterior (a-p) limb axis. [provided by RefSeq, Jul 2008]
GeneCards Summary for HOXD1 Gene
HOXD1 (Homeobox D1) is a Protein Coding gene. Among its related pathways are Developmental Biology and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. GO annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is HOXD3.
UniProtKB/Swiss-Prot for HOXD1 Gene
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.