HOXC@ Cluster
gene cluster GIFtS: 10
GCID: GC12U990034
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Homeobox C Cluster(Previous name: homeo box C cluster)
(Previous symbol: HOX3@)
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Aliases
for HOXC@ gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
10fRNAdb,
12H-InvDB,
13NCBI,
14NONCODE,
and/or 15RNAdb)
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| Aliases |
|---|
| Homeobox C Cluster1 2 | | HOX3@1 2 | | Homeo Box C Cluster1 |
Export aliases for HOXC@ gene to outside databases |
Summaries
for HOXC@ gene(According to Entrez Gene,
GeneCards,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
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GeneCards Summary for HOXC@ Gene:
HOXC@ (homeobox C cluster) is a gene cluster.
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Genomic Views
for HOXC@ gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 75),
Regulatory elements and Epigenetics data according to
QIAGEN, and/or
SwitchGear Genomics)
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TryGeneCards Plus | Regulatory elements:
 Search for regulatory transcription factor binding sites for HOXC@
Other transcription factors
Search Chromatin IP Primers for HOXC@
Epigenetics:
| | DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HOXC@ |
Genomic Location:
Chromosome:12
Entrez Gene cytogenetic band: 12q12-q13 HGNC cytogenetic band: 12q12-q13GeneLoc information about chromosome 12 |
Proteins
for HOXC@ gene
(According to
1UniProtKB,
HORDE,
2neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to PhosphoSitePlus,
Specific Peptides from DME,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Cloud-Clone Corp.,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Cloud-Clone Corp.,
Antibodies by
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
LSBio,
Abcam, and/or
Cloud-Clone Corp.)
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UniProtKB: --
|
Domains /
Families
for HOXC@ gene(According to HGNC, IUPHAR, InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
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Function
for HOXC@ gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
genOway,
transcription factor targeting from QIAGEN
and/or HOMER,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
SwitchGear Genomics,
Gene Editing from DNA2.0,
Clones from OriGene,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
ESI BIO,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene.)
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Molecular Function:
Genatlas biochemistry entry for HOXC@:homeo box region C (9 genes),patterning the primary and secondary axes of developing mouse embryo
Phenotypes:
5 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Hoxc):
HOXC@ for phenotypes About GeneDecksing
Animal Models:
MGI mouse knock-out Hoxctm1Nogu for HOXC@
Inhib. RNA
Products: |  | Browse OriGene RNAi
| | | Predesigned siRNA for gene silencing in human, mouse, rat HOXC@ |
Cell Line
Products: |  | GenScript Custom overexpressing Cell Line Services for HOXC@ | |  | Browse ESI BIO Cell Lines and PureStem Progenitors for HOXC@  | In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HOXC@ |
Localization
for HOXC@ gene
(According to UniProtKB, COMPARTMENTS Subcellular localization database,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene.)
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Pathways & Interactions
for HOXC@ gene
(SuperPaths according to PathCards,
Pathways according to
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Sino Biological,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
QIAGEN,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene).
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Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HOXC@
Interactions:
Search GeneGlobe Interaction Network for HOXC@
|
Drugs & Compounds
for HOXC@ gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience,
ApexBio,
HMDB,
BitterDB, and/or
Novoseek,
Ligands according to IUPHAR,
and Drugs according to DrugBank,
Enzo Life Sciences, and/or
PharmGKB)
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 Browse compounds at ApexBio
 Browse Tocris compounds for HOXC@
|
Transcripts
for HOXC@ gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
Conferences by KenesGroup,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
SwitchGear Genomics,
Tagged/untagged cDNA clones from
OriGene,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene, and/or
QIAGEN
)
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Inhib. RNA
Products: | | Browse OriGene RNAi
| |
| | Predesigned siRNA for gene silencing in human, mouse, rat HOXC@ |
|
Expression
for HOXC@ gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
Protein expression images according to data from SPIRE 1MOPED,
2PaxDb, and 3MaxQB,
plus additional links to
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
QIAGEN,
Primers from
OriGene, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
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Expression evidence for HOXC@:none
See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --
HOXC@ Protein expression data from MOPED1, PaxDb2 and
MaxQB3:  --
Custom PCR Arrays for HOXC@
Primer
Products: | | Browse OriGene qPCR
| | | Search Pre-validated RT2 qPCR
Primer Assays in human, mouse, rat HOXC@ | | | QuantiTect SYBR Green Assays in human, mouse, rat HOXC@ | | | QuantiFast Probe-based Assays in human, mouse, rat HOXC@ | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HOXC@ |
Orthologs
for HOXC@ gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
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This gene was present in the common ancestor of human and mouse.
Orthologs for HOXC@ gene from 1 species (see representative species ) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Hoxc5 |
homeobox C cluster |
-- |
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15 - |
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Paralogs
for HOXC@ gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Genomic Variants
for HOXC@ gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
4UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD), the Human Cytochrome P450 Allele
Nomenclature Database, and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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TryGeneCards Plus | | | Site Specific Mutation Identification with PCR Assays |
|
Disorders
/ Diseases
for HOXC@ gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Conferences by KenesGroup,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
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Publications
for HOXC@ gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
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PubMed articles for HOXC@ gene integrated from 10 sources:
(articles sorted by number of sources associating them with HOXC@) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Vertebrate homeobox gene nomenclature. (PubMed id 1358459)1, 3 Scott M.P. (Cell 1992)
- Nomenclature for human homeobox genes. (PubMed id 1973146)1, 3 McAlpine P.J. and Shows T.B. (Genomics 1990)
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External Searches for HOXC@ gene (in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing HOXC@ gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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|
Other Databases showing HOXC@ gene
(According to HUGE)
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Specialized Databases showing HOXC@ gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for HOXC@ | Pharmacogenomics, SNPs, Pathways |
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| | |
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TryGeneCards Plus | Patent Information for HOXC@ gene:
Search GeneIP for patents involving HOXC@
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for HOXC@ gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or
ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory,
genOway)
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|  | Block miRNA regulation of human, mouse, rat HOXC@ using miScript Target Protectors | | SeqTarget long-range PCR primers for resequencing HOXC@ | | | DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HOXC@ | | Predesigned siRNA for gene silencing in human, mouse, rat HOXC@ | | | QuantiFast Probe-based Assays in human, mouse, rat HOXC@ | | QuantiTect SYBR Green Assays in human, mouse, rat HOXC@ | | | Custom PCR Arrays for HOXC@ | | Search Chromatin IP Primers for HOXC@ | | | Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat HOXC@ | | Search GeneGlobe Interaction Network for HOXC@ | | | Search Regulatory tfbs for HOXC@ |
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| | | Search Tocris compounds for HOXC@ |
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 |  | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HOXC@ |
| |  |  |  |  | | | Search ThermoFisher Antibodies for HOXC@ |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat HOXC@ |
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