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HOXC11 Gene

protein-coding   GIFtS: 53
GCID: GC12P054366

Homeobox C11

(Previous name: homeo box C11)
(Previous symbol: HOX3H)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Homeobox C111 2
HOX3H1 2 3
Homeo Box C111 2
Homeobox Protein Hox-3H2 3
Homeobox Protein Hox-C112

External Ids:    HGNC: 51231   Entrez Gene: 32272   Ensembl: ENSG000001233887   OMIM: 6055595   UniProtKB: O432483   

Export aliases for HOXC11 gene to outside databases

Previous GC identifers: GC12M054415 GC12P054479 GC12P054083 GC12P052653 GC12P051405


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for HOXC11 Gene:
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of
transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals
possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different
chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes
located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the
lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced
variant encoding a shorter isoform has been described but its full-length nature has not been determined.
(provided by RefSeq, Jul 2008)

GeneCards Summary for HOXC11 Gene:
HOXC11 (homeobox C11) is a protein-coding gene. GO annotations related to this gene include RNA polymerase II core promoter proximal region sequence-specific DNA binding and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription. An important paralog of this gene is HOXD11.

UniProtKB/Swiss-Prot: HXC11_HUMAN, O43248
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides
cells with specific positional identities on the anterior-posterior axis. Binds to a promoter element of the
lactase-phlorizin hydrolase gene

Gene Wiki entry for HOXC11 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NC_018923.2  NT_029419.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the HOXC11 gene promoter:
         Max1   E2F-3a   E2F-4   C/EBPbeta   E2F-5   Lmo2   E2F-2   E2F   E2F-1   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHOXC11 promoter sequence
   Search Chromatin IP Primers for HOXC11

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HOXC11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.3   Ensembl cytogenetic band:  12q13.13   HGNC cytogenetic band: 12q13.13

HOXC11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HOXC11 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P054366:  view genomic region     (about GC identifiers)

Start:
54,366,910 bp from pter      End:
54,371,427 bp from pter
Size:
4,518 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: HXC11_HUMAN, O43248 (See protein sequence)
Recommended Name: Homeobox protein Hox-C11  
Size: 304 amino acids; 33748 Da
Secondary accessions: A8K7D1 Q96DH2

Explore the universe of human proteins at neXtProt for HOXC11: NX_O43248

Explore proteomics data for HOXC11 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See HOXC11 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055027.1  
    ENSEMBL proteins: 
     ENSP00000446680   ENSP00000243082  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    HOXL: Homeoboxes / ANTP class : HOXL subclass

    5 InterPro protein domains:
     IPR021918 DUF3528
     IPR020479 Homeobox_metazoa
     IPR017970 Homeobox_CS
     IPR001356 Homeobox_dom
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry O43248

    ProtoNet protein and cluster: O43248

    UniProtKB/Swiss-Prot: HXC11_HUMAN, O43248
    Similarity: Belongs to the Abd-B homeobox family
    Similarity: Contains 1 homeobox DNA-binding domain


    Find genes that share domains with HOXC11           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HXC11_HUMAN, O43248
    Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides
    cells with specific positional identities on the anterior-posterior axis. Binds to a promoter element of the
    lactase-phlorizin hydrolase gene

         Genatlas biochemistry entry for HOXC11:
    homeo box C11(3H),homologous to mouse Hox-3.7,involved in mouse posterior limb patterning expressed in posterior
    limb

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding IDA9582375
    GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription IDA9582375
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity ----
    GO:0043565sequence-specific DNA binding ----
         
    Find genes that share ontologies with HOXC11           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for HOXC11:
     Synthetic lethal with Ras 

         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Hoxc11):
     cellular  limbs/digits/tail  renal/urinary system  reproductive system  skeleton 

    Find genes that share phenotypes with HOXC11           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Hoxc11tm1Mrc for HOXC11

       genOway: Develop your customized and physiologically relevant rodent model for HOXC11

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    miRTarBase miRNAs that target HOXC11:
    hsa-mir-744-5p (MIRT037653), hsa-mir-320b (MIRT036198), hsa-mir-484 (MIRT042340), hsa-mir-106a-5p (MIRT048337)

    Block miRNA regulation of human, mouse, rat HOXC11 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HOXC11 (see all 46):
    hsa-miR-21* hsa-miR-642a hsa-miR-3194-5p hsa-let-7d hsa-miR-1197 hsa-miR-513a-5p hsa-miR-15a hsa-miR-605
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    HXC11_HUMAN, O43248: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    mitochondrion4
    cytosol3

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005739mitochondrion ----

    Find genes that share ontologies with HOXC11           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including HOXC11: 
              Homeobox (HOX) Genes in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for HOXC11

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    Selected Interacting proteins for HOXC11 (O432483 ENSP000002430824) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CD2APQ9Y5K63, ENSP000003522644I2D: score=1 STRING: ENSP00000352264
    GTF2A1LQ9UNN43, ENSP000003845974I2D: score=1 STRING: ENSP00000384597
    GTF2H1P327803, ENSP000002659634I2D: score=1 STRING: ENSP00000265963
    MEIS1O004703, ENSP000002723694I2D: score=1 STRING: ENSP00000272369
    SMAD3P840223, ENSP000003329734I2D: score=1 STRING: ENSP00000332973
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001501skeletal system development ----
    GO:0001656metanephros development IEA--
    GO:0001759organ induction IEA--
    GO:0006355regulation of transcription, DNA-templated ----
    GO:0007492endoderm development TAS9582375

    Find genes that share ontologies with HOXC11           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HOXC11 (HXC11)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for HOXC11 gene: 
    NM_014212.3  

    Unigene Cluster for HOXC11:

    Homeobox C11
    Hs.127562  [show with all ESTs]
    Unigene Representative Sequence: NM_014212
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000546378(uc001sem.3) ENST00000243082
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate HOXC11 (see all 46):
    hsa-miR-21* hsa-miR-642a hsa-miR-3194-5p hsa-let-7d hsa-miR-1197 hsa-miR-513a-5p hsa-miR-15a hsa-miR-605
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      QuantiFast Probe-based Assays in human, mouse, rat HOXC11

    Additional mRNA sequence: 

    AJ000041.1 AK291946.1 BC001543.1 X99630.1 

    1 DOTS entry:

    DT.86838844 

    20 AceView cDNA sequences:

    BX384375 BM454815 CR602963 X99630 AJ000041 NM_014212 BC001543 BM792333 
    AL555641 AA953456 BE544348 BP380964 BP380768 BX095756 AU100254 BM791522 
    AU107978 BF315826 BX384374 AW291236 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HOXC11 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGCACTCCCC
    HOXC11 Expression
    About this image


    HOXC11 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Limb (Muscoskeletal System)    fully expand to see all 2 entries
             Limb Bud Mesenchyme Cells Limb Bud
     
     Bone (Muscoskeletal System)
             Prechondrocytic Mesenchymal Cells Zeugopod
     
     Mesoderm (Gastrulation Derivatives)
             Limb Bud Mesenchyme Cells Limb Bud
     
     Cartilage (Muscoskeletal System)
             Prechondrocytic Mesenchymal Cells Zeugopod
     
     Kidney (Urinary System)
             Metanephric Mesenchyme Cells Metanephric Mesenchyme
    HOXC11 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HOXC11 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.127562
        Pathway & Disease-focused RT2 Profiler PCR Array including HOXC11: 
              Homeobox (HOX) Genes in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for HOXC11 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hoxc111 , 5 homeobox C111, 5 93.64(n)1
    97.7(a)1
      15 (58.02 cM)5
    1096631  NM_001024842.11  NP_001020013.11 
     1029544275 
    chicken
    (Gallus gallus)
    Aves HOXC111 homeobox C11 74.25(n)
    77.26(a)
      430698  XM_428250.3  XP_428250.2 
    lizard
    (Anolis carolinensis)
    Reptilia HOXC116
    homeobox C11
    73(a)
    1 ↔ 1
    2(72097982-72102430)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.116032 Transcribed sequence with weak similarity to protein more 79.23(n)    BQ395576.1 
    zebrafish
    (Danio rerio)
    Actinopterygii hoxc11a1 homeo box C11a 68.22(n)
    67.67(a)
      30403  NM_131165.2  NP_571240.1 


    ENSEMBL Gene Tree for HOXC11 (if available)
    TreeFam Gene Tree for HOXC11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HOXC11 gene
    HOXD112  ENSG000002571842  HOXD102  HOXC132  HOXC102  HOXD122  HOXA92  HOXA132  
    HOXC92  HOXB132  HOXC122  HOXD132  HOXA112  HOXB92  HOXD92  HOXA102  
    2 SIMAP similar genes for HOXC11 using alignment to 2 protein entries:     HXC11_HUMAN (see all proteins):
    HOXA11    HOXD11

    Find genes that share paralogs with HOXC11           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HOXC11 (see all 114)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1902842171,2
    --51402198(+) TTTTCA/GTGGCC 1 -- us2k10--------
    rs1433896011,2
    C--51402270(+) TTAAGA/TTCTGA 1 -- us2k10--------
    rs1825071731,2
    --51402311(+) AGTGCA/GTAGAG 1 -- us2k10--------
    rs45129011,2
    C,F,A,H--51402464(-) CCATAT/GGTAAC 1 -- us2k129Minor allele frequency- G:0.37NS EA NA WA CSA 2777
    rs107836181,2
    C,F,A,H--51402503(+) TTATCT/CGGTTT 1 -- us2k1 tfbs322Minor allele frequency- C:0.47NS EA NA WA 2532
    rs1388392331,2
    --51402592(+) GGGTTA/GTGGAT 1 -- us2k10--------
    rs1419090301,2
    --51402630(+) TTTCCC/TCTGAG 1 -- us2k10--------
    rs1463358261,2
    --51402703(+) CCTGGC/TAGCTC 1 -- us2k10--------
    rs45113241,2
    C,F,A,H--51402763(-) CTGGGT/CCCAAG 1 -- us2k125Minor allele frequency- C:0.38NS EA NA WA CSA 2357
    rs1856894471,2
    --51402810(+) ACATGA/TGTCCT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for HOXC11 (54366910 - 54371427 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for HOXC11:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv899100CNV Loss21882294
    nsv826379CNV Gain20364138
    nsv428282CNV Gain18775914
    dgv512e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    OMIM gene information: 605559    OMIM disorders: --


    Find genes that share disorders with HOXC11           About GenesLikeMe


    Export disorders for HOXC11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HOXC11 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with HOXC11)
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    1. The HOXC11 homeodomain protein interacts with the lactase-phlorizin hydrolase promoter and stimulates HNF1alpha-dependent transcription. (PubMed id 9582375)1, 2, 9 Mitchelmore C.E.... Noren O. (J. Biol. Chem. 1998)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete mutation analysis panel of the 39 human HOX genes. (PubMed id 11857506)1, 2 Kosaki K.... Matsuo N. (Teratology 2002)
    4. Vertebrate homeobox gene nomenclature. (PubMed id 1358459)1, 3 Scott M.P. (Cell 1992)
    5. Nomenclature for human homeobox genes. (PubMed id 1973146)1, 3 McAlpine P.J. and Shows T.B. (Genomics 1990)
    6. Development and application of a DNA microarray-based yeast two-hybrid system. (PubMed id 23275563)1 Suter B....Wanker E.E. (Nucleic Acids Res. 2013)
    7. Interaction of developmental transcription factor HOXC11 with steroid receptor coactivator SRC-1 mediates resistance to endocrine therapy in breast cancer [corrected]. (PubMed id 20145129)1 McIlroy M....Young L.S. (Cancer Res. 2010)
    8. An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (Cell 2010)
    9. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)
    10. Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach. (PubMed id 18654987)1 Thalappilly S....Dusetti N.J. (Proteomics 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 3227 HGNC: 5123 AceView: HOXC11 Ensembl:ENSG00000123388 euGenes: HUgn3227
    ECgene: HOXC11 H-InvDB: HOXC11

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HOXC11 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for HOXC11 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for HOXC11 gene:
    Search GeneIP for patents involving HOXC11

    GeneCards and IP:
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