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HOXC10 Gene

protein-coding   GIFtS: 51
GCID: GC12P054378

Homeobox C10

(Previous name: homeo box C10)
(Previous symbol: HOX3I)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Homeobox C101 2
HOX3I1 2 3
Homeo Box C101 2
Homeobox Protein Hox-3I2 3
Homeobox Protein Hox-C102
Homeoprotein C102

External Ids:    HGNC: 51221   Entrez Gene: 32262   Ensembl: ENSG000001808187   OMIM: 6055605   UniProtKB: Q9NYD63   

Export aliases for HOXC10 gene to outside databases

Previous GC identifers: GC12M054414 GC12P054491 GC12P054095 GC12P052665 GC12P051416


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for HOXC10 Gene:
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of
transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals
possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different
chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes
located in a cluster on chromosome 12. The protein level is controlled during cell differentiation and
proliferation, which may indicate this protein has a role in origin activation. (provided by RefSeq, Jul 2008)

GeneCards Summary for HOXC10 Gene:
HOXC10 (homeobox C10) is a protein-coding gene. Diseases associated with HOXC10 include cervical squamous cell carcinoma, and cervicitis. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is HOXD11.

UniProtKB/Swiss-Prot: HXC10_HUMAN, Q9NYD6
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides
cells with specific positional identities on the anterior-posterior axis

Gene Wiki entry for HOXC10 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000012.12  NC_018923.2  NT_029419.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the HOXC10 gene promoter:
         E2F-4   E2F-3a   E2F   E2F-1   FOXO1a   E2F-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHOXC10 promoter sequence
   Search Chromatin IP Primers for HOXC10

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HOXC10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.3   Ensembl cytogenetic band:  12q13.13   HGNC cytogenetic band: 12q13.13

HOXC10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HOXC10 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P054378:  view genomic region     (about GC identifiers)

Start:
54,378,849 bp from pter      End:
54,384,063 bp from pter
Size:
5,215 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: HXC10_HUMAN, Q9NYD6 (See protein sequence)
Recommended Name: Homeobox protein Hox-C10  
Size: 342 amino acids; 38073 Da
Secondary accessions: O15219 O15220 Q9BVD5

Explore the universe of human proteins at neXtProt for HOXC10: NX_Q9NYD6

Explore proteomics data for HOXC10 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See HOXC10 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_059105.2  
    ENSEMBL proteins: 
     ENSP00000421946   ENSP00000307321  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    HOXL: Homeoboxes / ANTP class : HOXL subclass

    4 InterPro protein domains:
     IPR020479 Homeobox_metazoa
     IPR017970 Homeobox_CS
     IPR001356 Homeobox_dom
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry Q9NYD6

    ProtoNet protein and cluster: Q9NYD6

    UniProtKB/Swiss-Prot: HXC10_HUMAN, Q9NYD6
    Similarity: Belongs to the Abd-B homeobox family
    Similarity: Contains 1 homeobox DNA-binding domain


    HOXC10 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HXC10_HUMAN, Q9NYD6
    Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides
    cells with specific positional identities on the anterior-posterior axis

         Genatlas biochemistry entry for HOXC10:
    homeo box C10(3I),homologous to mouse Hox-3.6,involved in mouse posterior limb patterning,expressed in posterior
    limb

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0043565sequence-specific DNA binding IEA--
         
    HOXC10 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for HOXC10:
     Decreased viability with pacli 

         7 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Hoxc10):
     behavior/neurological  growth/size/body  limbs/digits/tail  muscle  nervous system 
     renal/urinary system  skeleton 

    HOXC10 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Hoxc10tm1Mrc for HOXC10

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HOXC10
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for HOXC10

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HOXC10
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HOXC10

    miRNA
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    miRTarBase miRNAs that target HOXC10:
    hsa-mir-103a-3p (MIRT027074), hsa-mir-221-3p (MIRT024207)

    Block miRNA regulation of human, mouse, rat HOXC10 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HOXC10 (see all 48):
    hsa-miR-136 hsa-miR-1321 hsa-miR-1260b hsa-miR-765 hsa-miR-507 hsa-miR-10b* hsa-miR-629* hsa-miR-510
    SwitchGear 3'UTR luciferase reporter plasmidHOXC10 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for HOXC10
    Predesigned siRNA for gene silencing in human, mouse, rat HOXC10

    Gene Editing
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    Sino Biological Human cDNA Clone for HOXC10
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HOXC10

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HOXC10


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    HXC10_HUMAN, Q9NYD6: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0019907colocalizes with cyclin-dependent protein kinase activating kinase holoenzyme complex IDA11445587

    HOXC10 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Arrays including HOXC10: 
              Stem Cell Transcription Factors in human mouse rat
              Homeobox (HOX) Genes in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for HOXC10

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    Selected Interacting proteins for HOXC10 (Q9NYD63 ENSP000003073214) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EGFRP005333, ENSP000002754934I2D: score=3 STRING: ENSP00000275493
    CDC27P302603I2D: score=1 
    SUMO2ENSP000004059654STRING: ENSP00000405965
    LINSENSP000003184234STRING: ENSP00000318423
    NCAPHENSP000002404234STRING: ENSP00000240423
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001501skeletal system development IEA--
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated ----
    GO:0008284positive regulation of cell proliferation TAS10835276
    GO:0009952anterior/posterior pattern specification IEA--

    HOXC10 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HOXC10 (HXC10)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for HOXC10 gene: 
    NM_017409.3  

    Unigene Cluster for HOXC10:

    Homeobox C10
    Hs.44276  [show with all ESTs]
    Unigene Representative Sequence: NM_017409
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000515593 ENST00000303460(uc001sen.3) ENST00000511575 ENST00000514415
    ENST00000513413
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat HOXC10 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HOXC10 (see all 48):
    hsa-miR-136 hsa-miR-1321 hsa-miR-1260b hsa-miR-765 hsa-miR-507 hsa-miR-10b* hsa-miR-629* hsa-miR-510
    SwitchGear 3'UTR luciferase reporter plasmidHOXC10 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for HOXC10
    Predesigned siRNA for gene silencing in human, mouse, rat HOXC10
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: HOXC10 (NM_017409)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HOXC10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HOXC10
    Primer
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    OriGene qPCR primer pairs and template standards for HOXC10
    OriGene qSTAR qPCR primer pairs in human, mouse for HOXC10
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat HOXC10
      QuantiTect SYBR Green Assays in human, mouse, rat HOXC10
      QuantiFast Probe-based Assays in human, mouse, rat HOXC10

    Additional mRNA sequence: 

    AF255675.1 AK313759.1 BC001293.1 BT009921.1 X99685.1 

    4 DOTS entries:

    DT.448032  DT.91692757  DT.95307803  DT.91909674 

    Selected AceView cDNA sequences (see all 228):

    AI380130 AW469953 AA629181 AI275813 NM_004503 AI200419 NM_153693 NM_153633 
    BQ890449 BF058345 AA331371 BF591158 BM758123 BM825403 NM_018953 BF057562 
    BQ962391 AI215607 BF434131 BM127322 BM127627 CR615968 AA827833 AL558161 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HOXC10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAGCTTCCTT
    HOXC10 Expression
    About this image


    HOXC10 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Skeletal Muscle (Muscoskeletal System)
             Muscle Progenitor Cells Thoracic Ventrolateral Dermomyotome Lip
     
     Kidney (Urinary System)
             Metanephric Mesenchyme Cells Metanephric Mesenchyme
     
     Somite (Muscoskeletal System)
             Muscle Progenitor Cells Thoracic Ventrolateral Dermomyotome Lip
     
     Motor Neurons (Nervous System)
             Lateral motor column neuron-like cells
     
     Neurons
             Lateral motor column neuron-like cells
    HOXC10 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HOXC10 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.44276
        Pathway & Disease-focused RT2 Profiler PCR Arrays including HOXC10: 
              Stem Cell Transcription Factors in human mouse rat
              Homeobox (HOX) Genes in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HOXC10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for HOXC10 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hoxc101 , 5 homeobox C101, 5 95.22(n)1
    97.37(a)1
      15 (58.03 cM)5
    2094481  NM_010462.51  NP_034592.21 
     1029667965 
    chicken
    (Gallus gallus)
    Aves HOXC101 homeobox C10 73.2(n)
    73.98(a)
      770471  XM_001233805.3  XP_001233806.2 
    lizard
    (Anolis carolinensis)
    Reptilia HOXC106
    homeobox C10
    65(a)
    1 ↔ 1
    2(72078969-72085579)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.218642 Xenopus laevis Hoxc10 mRNA, complete cds 77.41(n)    AY167741.1 
    zebrafish
    (Danio rerio)
    Actinopterygii hoxc10a1 homeo box C10a 54.22(n)
    51.62(a)
      100535576  NM_001254944.1  NP_001241873.1 


    ENSEMBL Gene Tree for HOXC10 (if available)
    TreeFam Gene Tree for HOXC10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HOXC10 gene
    HOXD112  ENSG000002571842  HOXD102  HOXC132  HOXD122  HOXA92  HOXA132  HOXC92  
    HOXB132  HOXC122  HOXC112  HOXD132  HOXA112  HOXB92  HOXD92  HOXA102  
    4 SIMAP similar genes for HOXC10 using alignment to 3 protein entries:     HXC10_HUMAN (see all proteins):
    HOXD10    HOXA10    HOXA9    HOXC9

    HOXC10 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HOXC10 (see all 143)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1484037071,2
    --54377023(+) GAAATA/GTCAGT 1 -- us2k10--------
    rs1896372111,2
    --54377121(+) TGGTGA/GGGAAA 1 -- us2k10--------
    rs587424861,2
    C,F--54377192(+) GGCGGT/CGGGAC 1 -- us2k11Minor allele frequency- C:0.10WA 118
    rs1811167311,2
    --54377217(+) ATTGAC/TTGCTG 1 -- us2k10--------
    rs1424895421,2
    --54377293(+) GCCACG/TGTGAC 1 -- us2k10--------
    rs731125241,2
    C--54377334(+) ATCTCC/TCCTGG 1 -- us2k10--------
    rs1859562371,2
    --54377831(+) CTTCTC/GTGGGT 1 -- us2k10--------
    rs1912029621,2
    --54377840(+) GTCGGC/GTTTTG 1 -- us2k10--------
    rs1121194011,2
    C,F--54378117(+) GGTCTC/TTGGCT 1 -- us2k11Minor allele frequency- T:0.50NA 2
    rs116130411,2
    C,F,H--54378336(+) AGTCCT/CGTTTG 1 -- us2k17Minor allele frequency- C:0.03NS NA 802

    HapMap Linkage Disequilibrium report for HOXC10 (54378849 - 54384063 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for HOXC10:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv899100CNV Loss21882294
    nsv826379CNV Gain20364138
    nsv428282CNV Gain18775914
    dgv512e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing HOXC10
    DNA2.0 Custom Variant and Variant Library Synthesis for HOXC10

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 605560    OMIM disorders: --

    4 diseases for HOXC10:    
    About MalaCards
    cervical squamous cell carcinoma    cervicitis    squamous cell carcinoma    neuronitis


    HOXC10 for disorders           About GeneDecksing


    Export disorders for HOXC10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HOXC10 gene, integrated from 10 sources (see all 21):
    (articles sorted by number of sources associating them with HOXC10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Selection of homeotic proteins for binding to a human DNA replication origin. (PubMed id 10835276)1, 2, 9 de Stanchina E.... Biamonti G. (J. Mol. Biol. 2000)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Distinct patterns of all-trans retinoic acid dependent expression of HOXB and HOXC homeogenes in human embryonal and small-cell lung carcinoma cell lines. (PubMed id 9357979)1, 2 Flagiello D.... Malfoy B. (FEBS Lett. 1997)
    4. Vertebrate homeobox gene nomenclature. (PubMed id 1358459)1, 3 Scott M.P. (Cell 1992)
    5. Gene expression analysis of preinvasive and invasive cervical squamous cell carcinomas identifies HOXC10 as a key mediator of invasion. (PubMed id 17974957)1, 9 Zhai Y....Cho K.R. (Cancer Res. 2007)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    7. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    8. Comparative proteomic analysis identifies a role for SUMO in protein quality control. (PubMed id 21693764)1 Tatham M.H....Hay R.T. (Sci Signal 2011)
    9. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    10. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 3226 HGNC: 5122 AceView: HOXC6 Ensembl:ENSG00000180818 euGenes: HUgn3226
    ECgene: HOXC10 H-InvDB: HOXC10

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HOXC10 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for HOXC10 gene:
    Search GeneIP for patents involving HOXC10

    GeneCards and IP:
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