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HOXB9 Gene

protein-coding   GIFtS: 53
GCID: GC17M046694

Homeobox B9

(Previous name: homeo box B9)
(Previous symbols: HOX2E, HOX2)
  See HOXB9-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Homeobox B91 2     Homeobox Protein Hox-2E2 3
HOX2E1 2 3 5     HOX-2.52
HOX21 2     Homeo Box 2E2
Homeo Box B91 2     Homeobox Protein Hox-B92
Homeobox Protein Hox-2.52 3     

External Ids:    HGNC: 51201   Entrez Gene: 32192   Ensembl: ENSG000001706897   OMIM: 1429645   UniProtKB: P174823   

Export aliases for HOXB9 gene to outside databases

Previous GC identifers: GC17M046409 GC17M049179 GC17M047040 GC17M047173 GC17M044053 GC17M042067


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for HOXB9 Gene:
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is
included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a
sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased
expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer. (provided by
RefSeq, Jul 2008)

GeneCards Summary for HOXB9 Gene:
HOXB9 (homeobox B9) is a protein-coding gene. Diseases associated with HOXB9 include papillary thyroid carcinoma, and lung cancer. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is HOXD11.

UniProtKB/Swiss-Prot: HXB9_HUMAN, P17482
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides
cells with specific positional identities on the anterior-posterior axis

Gene Wiki entry for HOXB9 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NC_018928.2  NT_010783.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the HOXB9 gene promoter:
         E2F-4   E2F-3a   E2F-5   AML1a   E2F-2   E2F   E2F-1   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHOXB9 promoter sequence
   Search Chromatin IP Primers for HOXB9

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HOXB9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.3   Ensembl cytogenetic band:  17q21.32   HGNC cytogenetic band: 17q21.32

HOXB9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HOXB9 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M046694:  view genomic region     (about GC identifiers)

Start:
46,698,518 bp from pter      End:
46,703,839 bp from pter
Size:
5,322 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: HXB9_HUMAN, P17482 (See protein sequence)
Recommended Name: Homeobox protein Hox-B9  
Size: 250 amino acids; 28059 Da
Developmental stage: Expressed in whole embryos and fetuses at 5-9 weeks from conception
Secondary accessions: B2RDB7 Q9H1I1

Explore the universe of human proteins at neXtProt for HOXB9: NX_P17482

Explore proteomics data for HOXB9 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See HOXB9 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_076922.1  
    ENSEMBL proteins: 
     ENSP00000309439   ENSP00000447530  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    HOXL: Homeoboxes / ANTP class : HOXL subclass

    Selected InterPro protein domains (see all 6):
     IPR020479 Homeobox_metazoa
     IPR006711 Hox9_activation_N
     IPR017112 Homeobox_Hox9
     IPR017970 Homeobox_CS
     IPR001356 Homeobox_dom

    Graphical View of Domain Structure for InterPro Entry P17482

    ProtoNet protein and cluster: P17482

    2 Blocks protein domains:
    IPB000047 Lambda and other repressor helix-turn-helix signature
    IPB006711 Hox9 activation region


    UniProtKB/Swiss-Prot: HXB9_HUMAN, P17482
    Similarity: Belongs to the Abd-B homeobox family
    Similarity: Contains 1 homeobox DNA-binding domain


    Find genes that share domains with HOXB9           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HXB9_HUMAN, P17482
    Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides
    cells with specific positional identities on the anterior-posterior axis

         Genatlas biochemistry entry for HOXB9:
    homeo box B9(2E),homologous to mouse Hox-2.5,Drosophila abd-B

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0005515protein binding IPI10617598
    GO:0043565sequence-specific DNA binding IEA--
         
    Find genes that share ontologies with HOXB9           About GenesLikeMe


    Phenotypes:
         6 MGI mutant phenotypes (inferred from 1 allele(MGI details for Hoxb9):
     endocrine/exocrine gland  hematopoietic system  immune system  integument  limbs/digits/tail 
     skeleton 

    Find genes that share phenotypes with HOXB9           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Hoxb9tm1Mrc for HOXB9

       genOway: Develop your customized and physiologically relevant rodent model for HOXB9

    miRNA
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    miRTarBase miRNAs that target HOXB9:
    hsa-mir-192-5p (MIRT026516), hsa-mir-215-5p (MIRT024768)

    Block miRNA regulation of human, mouse, rat HOXB9 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HOXB9 (see all 23):
    hsa-miR-3689b hsa-miR-4286 hsa-miR-1224-3p hsa-miR-1260b hsa-miR-4305 hsa-miR-339-5p hsa-miR-570 hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmidHOXB9 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat HOXB9

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    Addgene plasmids for HOXB9 

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    eBioscience FlowRNA Probe Sets ( VA1-10733) for HOXB9 


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    HXB9_HUMAN, P17482: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    mitochondrion4

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005739mitochondrion IDA--

    Find genes that share ontologies with HOXB9           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for HOXB9 About    
    See pathways by source

    SuperPathContained pathways About
    1Cyclins and Cell Cycle Regulation
    Cell Cycle Control by BTG Proteins0.36

    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for HOXB9
        Cell Cycle Control by BTG Proteins


        Pathway & Disease-focused RT2 Profiler PCR Array including HOXB9: 
              Homeobox (HOX) Genes in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for HOXB9

    STRING Interaction Network Preview (showing 5 interactants - click image to see 20)

    Selected Interacting proteins for HOXB9 (P174821, 2, 3 ENSP000003094394) via UniProtKB, MINT, STRING, and/or I2D (see all 22)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SAT1P216731, 2, 3, ENSP000003685724EBI-745290,EBI-711613 MINT-68157 I2D: score=5 STRING: ENSP00000368572
    RBPMSQ930622, 3, ENSP000003401764MINT-67929 I2D: score=5 STRING: ENSP00000340176
    MDFIQ997501, 2, 3, ENSP000002303214EBI-745290,EBI-724076 MINT-67244 I2D: score=5 STRING: ENSP00000230321
    KRTAP4-12Q9BQ662, 3, ENSP000003775824MINT-66644 I2D: score=5 STRING: ENSP00000377582
    CREBBPQ927933, ENSP000002623674I2D: score=2 STRING: ENSP00000262367
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated ----
    GO:0007275multicellular organismal development ----
    GO:0009952anterior/posterior pattern specification IEA--
    GO:0030879mammary gland development IEA--

    Find genes that share ontologies with HOXB9           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HOXB9 (HXB9)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for HOXB9 gene: 
    NM_024017.4  

    Unigene Cluster for HOXB9:

    Homeobox B9
    Hs.463350  [show with all ESTs]
    Unigene Representative Sequence: NM_024017
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000311177(uc002inx.3) ENST00000550387
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate HOXB9 (see all 23):
    hsa-miR-3689b hsa-miR-4286 hsa-miR-1224-3p hsa-miR-1260b hsa-miR-4305 hsa-miR-339-5p hsa-miR-570 hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmidHOXB9 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AK026084.1 AK056123.1 AK315480.1 BC015565.1 

    3 DOTS entries:

    DT.309741  DT.100749432  DT.100749433 

    Selected AceView cDNA sequences (see all 82):

    BM784270 BX114117 NM_024017 AW078582 BF063337 BC015565 BF478046 AW973279 
    BM987589 BE350818 CA426693 AI761312 BG830524 AW881257 AK056414 AK056123 
    AI695505 BF939270 AA706441 AI285204 BQ219022 AW206245 BF766438 AA551797 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HOXB9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGCCTGGATG
    HOXB9 Expression
    About this image


    HOXB9 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 14) fully expand
     
     Tendon & Ligament
             Cervical Sclerotome Cells Cervical Mesenchymal Sclerotome
     
     Bone (Muscoskeletal System)    fully expand to see all 4 entries
             Cervical Sclerotome Cells Cervical Mesenchymal Sclerotome
     
     Cartilage (Muscoskeletal System)    fully expand to see all 4 entries
             Cervical Sclerotome Cells Cervical Mesenchymal Sclerotome
     
     Somite (Muscoskeletal System)    fully expand to see all 4 entries
             Cervical Sclerotome Cells Cervical Mesenchymal Sclerotome
     
     Gut Tube (Gastrointestinal Tract)
             Pre-Pancreatic Foregut Endoderm Cells Prepancreatic Dorsal Foregut Endoderm
    HOXB9 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HOXB9 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.463350
        Pathway & Disease-focused RT2 Profiler PCR Array including HOXB9: 
              Homeobox (HOX) Genes in human mouse rat

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for HOXB9 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hoxb91 , 5 homeobox B91, 5 95.87(n)1
    96.8(a)1
      11 (59.81 cM)5
    154171  NM_008270.21  NP_032296.21 
     962714575 
    chicken
    (Gallus gallus)
    Aves HOXB91 homeobox B9 78.81(n)
    82.52(a)
      771865  XM_001233690.3  XP_001233691.2 
    lizard
    (Anolis carolinensis)
    Reptilia HOXB96
    homeobox B9
    74(a)
    1 ↔ 1
    6(75637047-75645469)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia MGC757972 hypothetical protein MGC75797 77.67(n)    BC059757.1 
    zebrafish
    (Danio rerio)
    Actinopterygii hoxb9a2 homeo box B9a 80.27(n)   30344  AY391430.1 


    ENSEMBL Gene Tree for HOXB9 (if available)
    TreeFam Gene Tree for HOXB9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HOXB9 gene
    HOXD112  ENSG000002571842  HOXD102  HOXC132  HOXC102  HOXD122  HOXA92  HOXA132  
    HOXC92  HOXB132  HOXC122  HOXC112  HOXD132  HOXA112  HOXD92  HOXA102  
    6 SIMAP similar genes for HOXB9 using alignment to 2 protein entries:     HXB9_HUMAN (see all proteins):
    HOXA-9    HOXA10    HOXC9    HOXA9    HOXD9    HOXA11

    Find genes that share paralogs with HOXB9           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HOXB9 (see all 175)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs780010991,2
    C--46698076(+) GTGTTC/GCTCCC 1 -- ds50013Minor allele frequency- G:0.12NA EA 242
    rs1472964111,2
    C--46698116(+) AGGTGA/GCATTC 1 -- ds50010--------
    rs620645681,2
    C,F--46698228(+) CCAGAC/TCCTGT 1 -- ds50019Minor allele frequency- T:0.31NA WA CSA EA 370
    rs28758191,2
    C,F--46698492(+) AGAGCC/TAACAC 1 -- ds50011Minor allele frequency- T:0.04WA 118
    rs116532631,2
    C,F,H--46698610(+) CCCACT/CCCCAC 1 -- ut314Minor allele frequency- C:0.07WA NA 242
    rs88441,2
    C,F,O,H--46698710(-) TTGTCG/AGTGGC 1 -- ut31 ese315Minor allele frequency- A:0.08MN NS EA NA 2118
    rs38265411,2
    C--46698956(-) GGCTTG/TGCCTC 1 -- ut31 ese33Minor allele frequency- T:0.12NA EA 242
    rs38265401,2
    C--46699018(-) CAGAGA/GAGCCC 1 -- ut31 ese33Minor allele frequency- G:0.12NA EA 242
    rs1175138011,2
    C,F--46699071(+) CGTTGC/AGCGCT 1 -- ut311Minor allele frequency- A:0.03EA 120
    rs1864571421,2
    --46699188(+) TACAGG/TGGGGT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for HOXB9 (46698518 - 46703839 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for HOXB9:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv833469CNV Loss17160897
    dgv3222n71CNV Loss21882294
    dgv3223n71CNV Loss21882294
    dgv369n27CNV Loss19166990
    dgv3224n71CNV Loss21882294
    nsv833471CNV Gain17160897
    dgv988e1CNV Complex17122850

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 142964    OMIM disorders: --

    3 diseases for HOXB9:    
    About MalaCards
    papillary thyroid carcinoma    lung cancer    prostate cancer


    Find genes that share disorders with HOXB9           About GenesLikeMe

    Genetic Association Database (GAD): HOXB9
    Human Genome Epidemiology (HuGE) Navigator: HOXB9 (1 document)

    Export disorders for HOXB9 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HOXB9 gene, integrated from 10 sources (see all 40):
    (articles sorted by number of sources associating them with HOXB9)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Do HOXB9 and COL1A1 genes play a role in congenital dislocation of the hip? Study in a Caucasian population. (PubMed id 19341834)1, 4 Rouault K....FAcrec C. (Osteoarthr. Cartil. 2009)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete mutation analysis panel of the 39 human HOX genes. (PubMed id 11857506)1, 2 Kosaki K.... Matsuo N. (Teratology 2002)
    5. Vertebrate homeobox gene nomenclature. (PubMed id 1358459)1, 3 Scott M.P. (Cell 1992)
    6. Nomenclature for human homeobox genes. (PubMed id 1973146)1, 3 McAlpine P.J. and Shows T.B. (Genomics 1990)
    7. Differential expression of human HOX-2 genes along the anterior- posterior axis in embryonic central nervous system. (PubMed id 2570724)1, 2 Giampaolo A.... Peschle C. (Differentiation 1989)
    8. Organization of human class I homeobox genes. (PubMed id 2576652)1, 2 Boncinelli E.... Simeone A. (Genome 1989)
    9. Decreased expression of HOXB9 is related to poor overall survival in patients with gastric carcinoma. (PubMed id 23332081)1 Sha S....Wu K. (Dig Liver Dis 2013)
    10. HOXB9 expression promoting tumor cell proliferation and angiogenesis is associated with clinical outcomes in breast cancer patients. (PubMed id 22396001)1 Seki H....Kitagawa Y. (Ann. Surg. Oncol. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 3219 HGNC: 5120 AceView: HOXB9 Ensembl:ENSG00000170689 euGenes: HUgn3219
    ECgene: HOXB9 H-InvDB: HOXB9

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HOXB9 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for HOXB9 gene:
    Search GeneIP for patents involving HOXB9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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