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HOXB7 Gene

protein-coding   GIFtS: 59
GCID: GC17M046684

Homeobox B7

(Previous name: homeo box B7)
(Previous symbols: HOX2, HOX2C)
  See HOXB7-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Homeobox B71 2     HHO.C12
HOX2C1 2 3 5     Hox-2.32
HOX21 2     Homeo Box 2C2
Homeo Box B71 2     Homeo Box C1 Protein2
Homeobox Protein HHO.C12 3     Homeobox Protein Hox-B72
Homeobox Protein Hox-2C2 3     

External Ids:    HGNC: 51181   Entrez Gene: 32172   Ensembl: ENSG000002600277   OMIM: 1429625   UniProtKB: P096293   

Export aliases for HOXB7 gene to outside databases

Previous GC identifers: GC17M046395 GC17M049165 GC17M047026 GC17M047159 GC17M044039 GC17M042053


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for HOXB7 Gene:
This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is
included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a
sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased
expression of this gene is associated with some cases of melanoma and ovarian carcinoma. (provided by RefSeq, Jul
2008)

GeneCards Summary for HOXB7 Gene:
HOXB7 (homeobox B7) is a protein-coding gene. Diseases associated with HOXB7 include cytomegalovirus infection. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is HOXA7.

UniProtKB/Swiss-Prot: HXB7_HUMAN, P09629
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides
cells with specific positional identities on the anterior-posterior axis

Gene Wiki entry for HOXB7 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NC_018928.2  NT_010783.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the HOXB7 gene promoter:
         AML1a   STAT3   CUTL1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHOXB7 promoter sequence
   Search Chromatin IP Primers for HOXB7

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HOXB7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.3   Ensembl cytogenetic band:  17q21.32   HGNC cytogenetic band: 17q21.32

HOXB7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HOXB7 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M046684:  view genomic region     (about GC identifiers)

Start:
46,684,594 bp from pter      End:
46,710,934 bp from pter
Size:
26,341 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: HXB7_HUMAN, P09629 (See protein sequence)
Recommended Name: Homeobox protein Hox-B7  
Size: 217 amino acids; 24015 Da
Secondary accessions: A8K3N8 Q15957 Q53FN3 Q96BQ6

Explore the universe of human proteins at neXtProt for HOXB7: NX_P09629

Explore proteomics data for HOXB7 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys191, Lys193
  • Modification sites at PhosphoSitePlus

  • See HOXB7 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_004493.3  
    ENSEMBL proteins: 
     ENSP00000239165  

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    Cloud-Clone Corp. Proteins for HOXB7

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    HOXL: Homeoboxes / ANTP class : HOXL subclass

    Selected InterPro protein domains (see all 6):
     IPR001827 Homeobox_Antennapedia_CS
     IPR020479 Homeobox_metazoa
     IPR017995 Homeobox_antennapedia
     IPR017970 Homeobox_CS
     IPR001356 Homeobox_dom

    Graphical View of Domain Structure for InterPro Entry P09629

    ProtoNet protein and cluster: P09629

    1 Blocks protein domain: IPB001827 Homeobox protein

    UniProtKB/Swiss-Prot: HXB7_HUMAN, P09629
    Similarity: Belongs to the Antp homeobox family
    Similarity: Contains 1 homeobox DNA-binding domain


    Find genes that share domains with HOXB7           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HXB7_HUMAN, P09629
    Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides
    cells with specific positional identities on the anterior-posterior axis

         Genatlas biochemistry entry for HOXB7:
    homeo box B7(2C),homologous to mouse Hox-2.3,Drosophila Antp,Ubx,abd-A,expressed during early myelopoiesis

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity NAS1678287
    GO:0005515protein binding IPI17308091
    GO:0043565sequence-specific DNA binding IEA--
         
    Find genes that share ontologies with HOXB7           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for HOXB7:
     Decreased viability with pacli 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Hoxb7):
     hematopoietic system  immune system  skeleton 

    Find genes that share phenotypes with HOXB7           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Hoxb7tm1Mrc for HOXB7

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HOXB7
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for HOXB7

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HOXB7
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HOXB7

    miRNA
    Products:
        
    miRTarBase miRNAs that target HOXB7:
    hsa-mir-196a-5p (MIRT004244), hsa-mir-26b-5p (MIRT030282)

    Block miRNA regulation of human, mouse, rat HOXB7 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HOXB7 (see all 11):
    hsa-miR-4283 hsa-miR-520d-5p hsa-miR-548v hsa-miR-3935 hsa-miR-1236 hsa-miR-337-3p hsa-miR-196a hsa-miR-3927
    SwitchGear 3'UTR luciferase reporter plasmidHOXB7 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for HOXB7
    Predesigned siRNA for gene silencing in human, mouse, rat HOXB7

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    GenScript: all cDNA clones in your preferred vector: HOXB7 (NM_004502)
    Sino Biological Human cDNA Clone for HOXB7
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HOXB7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HOXB7
    Addgene plasmids for HOXB7 

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    Flow Cytometry
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    eBioscience FlowRNA Probe Sets ( VA1-12425) for HOXB7 


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    HXB7_HUMAN, P09629: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol3

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus NAS1678287
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--

    Find genes that share ontologies with HOXB7           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including HOXB7: 
              Homeobox (HOX) Genes in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for HOXB7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for HOXB7 (P096291, 3 ENSP000002391654) via UniProtKB, MINT, STRING, and/or I2D (see all 56)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PRKDCP785271, 3, ENSP000003134204EBI-1248457,EBI-352053 I2D: score=1 STRING: ENSP00000313420
    XRCC5P130101, 3EBI-1248457,EBI-357997 I2D: score=1 
    HOXB6P175093, ENSP000002256484I2D: score=1 STRING: ENSP00000225648
    XRCC6P129563, ENSP000003522574I2D: score=1 STRING: ENSP00000352257
    CREBBPQ927933, ENSP000002623674I2D: score=3 STRING: ENSP00000262367
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated NAS1678287
    GO:0007275multicellular organismal development NAS2885844
    GO:0009952anterior/posterior pattern specification IEA--
    GO:0030099myeloid cell differentiation IEA--

    Find genes that share ontologies with HOXB7           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HOXB7 (HXB7)

    1 Novoseek inferred chemical compound relationship for HOXB7 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    retinoic acid 32.2 14 17514648 (3), 12536483 (2), 12212112 (1)



    Find genes that share compounds with HOXB7           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for HOXB7 gene: 
    NM_004502.3  

    Unigene Cluster for HOXB7:

    Homeobox B7
    Hs.436181  [show with all ESTs]
    Unigene Representative Sequence: AK223249
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000239165(uc002inv.3) ENST00000567101 ENST00000467314
    miRNA
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    Block miRNA regulation of human, mouse, rat HOXB7 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HOXB7 (see all 11):
    hsa-miR-4283 hsa-miR-520d-5p hsa-miR-548v hsa-miR-3935 hsa-miR-1236 hsa-miR-337-3p hsa-miR-196a hsa-miR-3927
    SwitchGear 3'UTR luciferase reporter plasmidHOXB7 3' UTR sequence
    Inhib. RNA
    Products:
         
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    Predesigned siRNA for gene silencing in human, mouse, rat HOXB7
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    Addgene plasmids for HOXB7 
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat HOXB7
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    Additional mRNA sequence: 

    AK223249.1 AK290653.1 BC015345.1 M16937.1 M30598.1 

    3 DOTS entries:

    DT.446319  DT.92424265  DT.95299509 

    Selected AceView cDNA sequences (see all 95):

    AW445183 NM_004502 BF002423 BE300551 BG114527 AI475182 AI701595 AI628945 
    AI871676 BE302874 BE465468 AI380746 BX116422 BM561113 AI361891 AI478205 
    BF438390 BQ233410 BC015345 AI308944 AI808292 BM009732 AU120874 AI912169 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HOXB7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGAAAGGGAG
    HOXB7 Expression
    About this image


    HOXB7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Kidney (Urinary System)    fully expand to see all 5 entries
             mK3
             Intermediate mesoderm derivatives
     
     Motor Neurons (Nervous System)
             Motor neuron-like cells
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
     
     NULL (Uncategorized)
             Intermediate mesoderm derivatives
     
     Endothelium (Cardiovascular System)
             Human umbilical vein endothelial cells (HUVEC)
    HOXB7 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HOXB7 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.436181
        Pathway & Disease-focused RT2 Profiler PCR Array including HOXB7: 
              Homeobox (HOX) Genes in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HOXB7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for HOXB7 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hoxb71 , 5 homeobox B71, 5 93.59(n)1
    93.75(a)1
      11 (59.82 cM)5
    154151  NM_010460.21  NP_034590.21 
     962866235 
    chicken
    (Gallus gallus)
    Aves HOXB71 homeobox B7 76.65(n)
    76.81(a)
      425962  XM_003642790.2  XP_003642838.2 
    lizard
    (Anolis carolinensis)
    Reptilia HOXB76
    homeobox B7
    74(a)
    1 ↔ 1
    6(75614839-75621679)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.12102 Xenopus mRNA containing homeobox (XlHbox2) 81.78(n)    X06592.1 
    zebrafish
    (Danio rerio)
    Actinopterygii hoxb7a1 homeo box B7a 65.7(n)
    61.35(a)
      58044  NM_001115091.1  NP_001108563.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Antp3 midgut development specific RNA
    polymerase II more
    82(a)     --


    ENSEMBL Gene Tree for HOXB7 (if available)
    TreeFam Gene Tree for HOXB7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HOXB7 gene
    HOXA72  HOXB52  HOXC62  HOXC52  HOXB42  HOXA52  ENSG000002732662  HOXA42  
    HOXC82  HOXA62  ENSG000002730492  HOXD82  HOXB62  HOXB82  HOXD42  HOXC42  
    18 SIMAP similar genes for HOXB7 using alignment to 3 protein entries:     HXB7_HUMAN (see all proteins):
    HOX B6    HOXB4    HOXC13    HOXA-9    HOXA4    HOXA7
    HMX2    HOXB1    HOXB8    HOXD8    HOXB5    HOXA5
    HOXB6    HOXC4    HOXC5    HOXC6    HOXA6    HOXC8

    Find genes that share paralogs with HOXB7           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HOXB7 (see all 133)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1823860701,2
    --46684399(+) GTAAAG/TGGAAT 1 -- ds50010--------
    rs1466172551,2
    --46684407(+) AATGCA/CTGAGT 1 -- ds50010--------
    rs1401118301,2
    --46684421(+) ATATCA/GGGGTT 1 -- ds50010--------
    rs1498050301,2
    --46684440(+) GGCAGC/TCCCCC 1 -- ds50010--------
    rs1878294761,2
    --46684453(+) AGCAGA/GAGGCA 1 -- ds50010--------
    rs1466800901,2
    --46684633(+) TAGAT-/ACACACA 1 -- ut310--------
    rs793665131,2
    F--46684694(+) GCCAGG/ACGCTT 1 -- ut311Minor allele frequency- A:0.05WA 118
    rs1921176791,2
    --46684770(+) GGAGGC/GTCAGG 1 -- ut310--------
    rs1457382731,2
    C--46684782(+) GGGCAC/GGCAAC 1 -- ut310--------
    rs156891,2
    C,F,O,A,H--46684929(-) AAGGAT/CATTAT 1 -- ut3126Minor allele frequency- C:0.41MN NS EA NA WA CSA 2729

    HapMap Linkage Disequilibrium report for HOXB7 (46684594 - 46710934 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for HOXB7:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2676919CNV Deletion23128226
    dgv3223n71CNV Loss21882294
    dgv369n27CNV Loss19166990
    dgv3224n71CNV Loss21882294
    nsv833469CNV Loss17160897
    dgv3222n71CNV Loss21882294
    nsv833471CNV Gain17160897
    dgv988e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 142962    OMIM disorders: --

    1 disease for HOXB7:    
    About MalaCards
    cytomegalovirus infection


    Find genes that share disorders with HOXB7           About GenesLikeMe

    8 Novoseek inferred disease relationships for HOXB7 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    cmv infection 33.4 1 12536483 (1)
    glioblastoma 32.3 3 17514648 (2), 9681827 (1)
    breast carcinoma 22.2 1 9681827 (1)
    breast cancer 13.9 4 10435624 (1), 9736453 (1), 12414653 (1)
    melanoma 6.68 4 8756643 (3), 9681827 (1)
    tumors 3.84 7 19956843 (2), 12697323 (2), 11274429 (1)
    leukemia 3.42 1 9681827 (1)
    cancer 0 3 15756441 (1)

    Genetic Association Database (GAD): HOXB7
    Human Genome Epidemiology (HuGE) Navigator: HOXB7 (1 document)

    Export disorders for HOXB7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HOXB7 gene, integrated from 10 sources (see all 72):
    (articles sorted by number of sources associating them with HOXB7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Correlation between genetic variations in Hox clusters and Hirschsprung's disease. (PubMed id 17274802)1, 4 Garcia-BarcelA^ M.M....Tam P.K. (Ann. Hum. Genet. 2007)
    2. The proteomic reactor facilitates the analysis of affinity-purified proteins by mass spectrometry: application for identifying ubiquitinated proteins in human cells. (PubMed id 17203973)1, 2 Vasilescu J.... Figeys D. (J. Proteome Res. 2007)
    3. Vertebrate homeobox gene nomenclature. (PubMed id 1358459)1, 3 Scott M.P. (Cell 1992)
    4. Lymphoid expression and TATAA binding of a human protein containing an Antennapedia homeodomain. (PubMed id 1678287)1, 2 Baier L.J.... Nabel G.J. (Blood 1991)
    5. Nomenclature for human homeobox genes. (PubMed id 1973146)1, 3 McAlpine P.J. and Shows T.B. (Genomics 1990)
    6. Organization of human class I homeobox genes. (PubMed id 2576652)1, 2 Boncinelli E.... Simeone A. (Genome 1989)
    7. Lineage-restricted expression of homeobox-containing genes in human hematopoietic cell lines. (PubMed id 2573064)1, 2 Shen W.-F.... Lawrence H.J. (Proc. Natl. Acad. Sci. U.S.A. 1989)
    8. Two human homeobox genes, c1 and c8: structure analysis and expression in embryonic development. (PubMed id 2885844)1, 2 Simeone A....Peschle C. (Proc. Natl. Acad. Sci. U.S.A. 1987)
    9. Enforced expression of HOXB7 promotes hematopoietic stem cell proliferation and myeloid-restricted progenitor differentiation. (PubMed id 10208421)1, 9 CarA" A....Peschle C. (Oncogene 1999)
    10. Overexpression of HOXB7 homeobox gene in oral cancer induces cellular proliferation and is associated with poor prognosis. (PubMed id 19956843)1, 9 De Souza Setubal Destro M.F....Coletta R.D. (Int. J. Oncol. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Aliases
    Disorders
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      Query String
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 3217 HGNC: 5118 AceView: HOXB7 Ensembl:ENSG00000260027 euGenes: HUgn3217
    ECgene: HOXB7 H-InvDB: HOXB7

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HOXB7 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for HOXB7 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for HOXB7 gene:
    Search GeneIP for patents involving HOXB7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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