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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HOXB5 Gene

protein-coding   GIFtS: 55
GCID: GC17M046668

homeobox B5

(Previous name: homeo box B5 )
(Previous symbols: HOX2, HOX2A)
 Explore 13 diseases affiliated with
HOXB5 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for HOXB5    

Aliases
for HOXB5 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Homeobox B51 2     Homeobox Protein Hu-12 3
HOX2A1 2 3 5     HHO.C102
HOX21 2     HU-12
Homeo Box B51 2     Hox2.12
Homeobox Protein HHO.C102 3     Homeo Box 2A2
Homeobox Protein Hox-2A2 3     Homeobox Protein Hox-B52

External Ids:    HGNC: 51161   Entrez Gene: 32152   Ensembl: ENSG000001200757   OMIM: 1429605   UniProtKB: P090673   

Export aliases for HOXB5 gene to outside databases

Previous GC identifers: GC17M046379 GC17M049149 GC17M047010 GC17M047143 GC17M044023 GC17M042037


Summaries
for HOXB5 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for HOXB5:
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It
is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a
sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene
is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary
sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: HXB5_HUMAN, P09067
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells
with specific positional identities on the anterior-posterior axis

Gene Wiki entry for HOXB5


Genomic Views
for HOXB5 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010783.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HOXB5 gene promoter:
         E2F-4   AP-1   AML1a   ATF-2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: HOXB5 promoter sequence
   Search SABiosciences Chromatin IP Primers for HOXB5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HOXB5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.3   Ensembl cytogenetic band:  17q21.32   HGNC cytogenetic band: 17q21.32

HOXB5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HOXB5 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M046668:  view genomic region     (about GC identifiers)

Start:
 46,668,619 bp from pter      End:
 46,671,323 bp from pter
Size:
 2,705 bases      Orientation:
 minus strand

Proteins
for HOXB5 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: HXB5_HUMAN, P09067 (See protein sequence)
Recommended Name: Homeobox protein Hox-B5  
Size: 269 amino acids; 29434 Da
Subcellular location: Nucleus
Developmental stage: Embryo
Sequence caution: Sequence=AAA52681.1; Type=Erroneous initiation;
Secondary accessions: B2RC69 P09069 Q17RP4

Explore the universe of human proteins at neXtProt for HOXB5: NX_P09067

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P09067

    • HOXB5 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_002138.1  
    ENSEMBL proteins: 
     ENSP00000239151  

    Human Recombinant Protein Products: 
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    Novus Biologicals HOXB5 Lysates
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for HOXB5

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--


    HOXB5 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for HOXB5

    Protein Domains /
    Families
    for HOXB5 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HOXB5 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR001827 Homeobox_Antennapedia_CS
     IPR020479 Homeobox_metazoa
     IPR017995 Homeobox_antennapedia
     IPR017970 Homeobox_CS
     IPR001356 Homeodomain

    Graphical View of Domain Structure for InterPro Entry P09067

    ProtoNet protein and cluster: P09067

    1 Blocks protein family: IPB001827 Homeobox protein

    UniProtKB/Swiss-Prot: HXB5_HUMAN, P09067
    Similarity: Belongs to the Antp homeobox family
    Similarity: Contains 1 homeobox DNA-binding domain


    Function
    for HOXB5 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: HXB5_HUMAN, P09067
    Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells
    with specific positional identities on the anterior-posterior axis

         Genatlas biochemistry entry for HOXB5:
    homeo box B5(2A),homologous to mouse Hox-2.1,Drosophila Scr,involved in the positioning of the mouse upper limb bud

    miRNA
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    8/20 QIAGEN miScript miRNA Assays for microRNAs that regulate HOXB5 (see all 20):
    hsa-miR-1260b hsa-miR-200a hsa-miR-944 hsa-miR-340 hsa-miR-4267 hsa-miR-141 hsa-miR-7-1* hsa-miR-23a
    SwitchGear 3'UTR luciferase reporter plasmid: HOXB5 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HOXB5 (see all 4)
    OriGene shRNA RFP: HOXB5
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    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for HOXB5

    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for HOXB5

    In Situ Assay
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0043565sequence-specific DNA binding IEA--


    HOXB5 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for HOXB5:
     Increased gamma-H2AX phosphory  Synthetic lethal with Ras 

    Animal Models:
         Mouse knock-out Hoxb5tm1Mrc for HOXB5
         3 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Hoxb5):
     nervous system  no phenotypic analysis  skeleton 

    HOXB5 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for HOXB5 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for HOXB5

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for HOXB5 (P090673 ENSP000002391514) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    PBX3P404263I2D: score=1 
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0009653anatomical structure morphogenesis TAS3000607
    GO:0009952anterior/posterior pattern specification IEA--
    GO:0045446endothelial cell differentiation IEA--


    HOXB5 for ontologies           About GeneDecksing



    Drugs & Compounds
    for HOXB5 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HOXB5
    Search CenterWatch for drugs/clinical trials and news about HOXB5 / HXB5 

    Transcripts
    for HOXB5 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for HOXB5 gene: 
    NM_002147.3  

    Unigene Cluster for HOXB5:

    Homeobox B5
    Hs.654456  [show with all ESTs]
    Unigene Representative Sequence: M92299
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000239151(uc002inr.3)

    miRNA
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    8/20 QIAGEN miScript miRNA Assays for microRNAs that regulate HOXB5 (see all 20):
    hsa-miR-1260b hsa-miR-200a hsa-miR-944 hsa-miR-340 hsa-miR-4267 hsa-miR-141 hsa-miR-7-1* hsa-miR-23a
    SwitchGear 3'UTR luciferase reporter plasmid: HOXB5 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HOXB5 (see all 4)
    OriGene shRNA RFP: HOXB5
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HOXB5
    Clone
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    GenScript: all cDNA clones in your preferred vector: HOXB5 (NM_002147)
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HOXB5
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HOXB5

    Additional cDNA sequence: 

    AK314964.1 BC004454.1 BC008940.2 BC117247.1 M86726.1 M92299.1 X03794.1 

    3 DOTS entries:

    DT.92434272  DT.411060  DT.70102337 

    24/63 AceView cDNA sequences (see all 63):

    BE905057 AI052747 AW138080 AI970004 BQ001097 BF063905 BF516082 BM994836 
    BC004454 M86726 CB992024 BM797039 M92299 BE797469 AI281340 BF222398 
    CB991412 AW973515 BQ430385 AI420155 BC008940 BI766494 NM_002147 AA576890 

    GeneLoc Exon Structure


    Expression
    for HOXB5 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HOXB5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGTCTGGCTA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    HOXB5 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    5 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    SomiteCervical Mesenchymal SclerotomeCervical Sclerotome CellsBone, Cartilage, Tendons & Ligaments
    LimbLimb BudLimb Bud Mesenchyme CellsMesoderm
    LungLung MesodermDistal Mesodermal Progenitor CellsLung
    Primitive StreakPosterior Primitive StreakHemangioblastsBlood, Endothelium
    LimbLimb BudLimb
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 10/11 LifeMap Cells (see all 11) 
    NameCategory
    PureStem™ endothelial Progenitor 30-SM2-3 (Embryonic Progenitor Cell)Blood, Endothelium
    PureStem™ endothelial progenitor 30-SM2-1 (Embryonic Progenitor Cell)Endothelium
    PureStem™ endothelial progenitor RP1-MV2-18 (Embryonic Progenitor Cell)Endothelium
    PureStem™ myogenic progenitor Z11 (Embryonic Progenitor Cell)Heart, Myocardium, Smooth Muscle
    PureStem™ progenitor RASMO12 (Embryonic Progenitor Cell)
    PureStem™ progenitor SK17 (Embryonic Progenitor Cell)
    PureStem™ progenitor W10 (Embryonic Progenitor Cell)
    Primordial-like germ cells (cKIT+ SSEA1+ VASA+) (Derivation of primor...)
    Podocalyxin+, CD24+, GCTM2- (Derivation and sorti...)
    Mesendoderm (Derivation and sorti...)

    See HOXB5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HOXB5

    SOURCE GeneReport for Unigene cluster: Hs.654456

    UniProtKB/Swiss-Prot: HXB5_HUMAN, P09067
    Tissue specificity: Spinal cord

        SABiosciences Expression via Pathway-Focused PCR Array including HOXB5: 
              Stem Cell Transcription Factors in human mouse rat

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    In Situ
    Assay Products:     
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    Orthologs
    for HOXB5 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for HOXB5 gene from 6/18 species (see all 18)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves HOXB51 homeobox B5 79.67(n)
    85.23(a)    		   425096  NM_001025355.1  NP_001020526.1 
    lizard
    (Anolis carolinensis)    		 Reptilia HOXB56
    		 --
    		 77(a)
    		 1 ↔ 1
    		 6(75594586-75596979)
    African clawed frog
    (Xenopus laevis)    		 Amphibia hoxb5-A2 homeo box B5 80.06(n)    X07104.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii hoxb5a2 homeo box B5a 79.34(n)   30317  NM_131101.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Scr1 , 3 midgut development specific RNA polymerase
    II more3
    Sex combs reduced1    		 73(a)3
    50.96(n)1
    42.67(a)1    		   3 84A53
    408331  NM_206443.21  NP_996165.11 
    worm
    (Caenorhabditis elegans)    		 Secernentea lin-396
    		 Homeobox protein lin-39
    		 25(a)
    		 possible ortholog
    		 III(7528603-7536567)


    ENSEMBL Gene Tree for HOXB5 (if available)
    TreeFam Gene Tree for HOXB5 (if available) 

    Paralogs
    for HOXB5 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HOXB5 gene
    GSX12  HOXA72  HOXA12  HOXD12  HOXA22  HOXB32  HOXC62  GSX22  
    HOXC52  HOXB42  HOXA52  HOXA42  HOXD32  HOXC82  HOXA62  HOXA32  
    HOXD82  HOXB12  HOXB62  HOXB82  HOXD42  HOXB22  HOXB72  PDX12  
    HOXC42  
    11 SIMAP similar genes for HOXB5 using alignment to 1 protein entry:     HXB5_HUMAN:
    HOXC6    HOXA4    HOXA5    HOXB4    HOXD8    HOXC4
    HOXA7    HOXB7    HOXC5    HOXD4    HOXA6

    HOXB5 for paralogs           About GeneDecksing



    Genomic Variants
    for HOXB5 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/76 NCBI SNPs in HOXB5 are shown (see all 76)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 17 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs354029071,2
    		C--46668176(+) TTTTTT/-GCTTT 5 -- us2k1 ds5001 int11Minor allele frequency- -:0.00NA 2
    rs1382352431,2
    		--46668405(+) CCCACA/GTGGGG 5 -- us2k1 int1 ds50010--------
    rs1815796471,2
    		--46668844(+) ATTCAC/GAGAGA 5 -- us2k1 int1 ut310--------
    rs8727601,2
    		C,F,O,H,--46668951(-) GAAGAT/CAGTGA 5 -- us2k1 int1 ut3123Minor allele frequency- C:0.10MN NA EA NS WA 2888
    rs1844837391,2
    		--46669045(+) GGGAGA/TGAGGA 5 -- us2k1 ut31 int10--------
    rs1899806171,2
    		--46669226(+) GAGTTC/TACATT 5 -- us2k1 ut31 int10--------
    rs30879961,2
    		C,F,A,H,--46669363(-) ATAATA/TATTAT 5 -- us2k1 ut31 int19Minor allele frequency- T:0.15MN WA NA CSA EA 553
    rs92991,2
    		C,F,A,H,--46669430(-) GTTTGG/ATCTTA 5 -- us2k1 ut31 int121Minor allele frequency- A:0.45MN NS EA NA WA 2718
    rs571832841,2
    		C,F,--46669456(+) AAGGCG/AANNNN 5 -- us2k1 int1 ut311Minor allele frequency- A:0.14WA 118
    rs1460339381,2
    		C,--46669538(+) GCACGA/GGCTCT 5 -- us2k1 ut31 int10--------

    HapMap Linkage Disequilibrium report for HOXB5 (46668619 - 46671323 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for HOXB5
         2 CNVs: 53230 4040
    Human Gene Mutation Database (HGMD): HOXB5

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    Disorders / Diseases
    for HOXB5 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    HOXB5 for disorders           About GeneDecksing

    OMIM gene information: 142960    OMIM disorders: --

    13 diseases for HOXB5:    About MalaCards
    acute myeloid leukemia    myeloid leukemia    congenital diaphragmatic hernia    leukemia
    vacterl association    oral squamous cell carcinoma    squamous cell carcinoma    hernia
    teratocarcinoma    ovarian carcinoma    carcinoma    neuroblastoma
    thyroiditis

    1 disease from the University of Copenhagen DISEASES database for HOXB5:
    Gastroschisis

    Export disorders for HOXB5 gene to outside databases

    Publications
    for HOXB5 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HOXB5 gene, integrated from 9 sources (see all 34):
    (articles sorted by number of sources associating them with HOXB5)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Cooperative DNA binding of the highly conserved human Hox 2.1 homeodomain gene product. (PubMed id 1355360)1, 2 Galang C.K. and Hauser C.A. (1992)
    3. Vertebrate homeobox gene nomenclature. (PubMed id 1358459)1, 3 Scott M.P. (1992)
    4. Nomenclature for human homeobox genes. (PubMed id 1973146)1, 3 McAlpine P.J. and Shows T.B. (1990)
    5. Organization of human class I homeobox genes. (PubMed id 2576652)1, 2 Boncinelli E.... Simeone A. (1989)
    6. A human homoeo box gene specifically expressed in spinal cord during embryonic development. (PubMed id 3453105)1, 2 Simeone A.... Peschle C. (1986)
    7. Expression of homologous homeo-box-containing genes in differentiated human teratocarcinoma cells and mouse embryos. (PubMed id 4075393)1, 2 Hauser C.A....Tjian R. (1985)
    8. Human DNA sequences homologous to a protein coding region conserved between homeotic genes of Drosophila. (PubMed id 6091895)1, 2 Levine M.... Tjian R. (1984)
    9. Expression of Hoxb-5 during human lung development and in congenital lung malformations. (PubMed id 14632303)1, 9 Volpe M.V....Nielsen H.C. (2003)
    10. A genome-wide association meta-analysis identifies new childhood obesity loci. (PubMed id 22484627)1 Bradfield J.P....Grant S.F. (2012)

    External Searches for HOXB5 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    Genome Databases showing HOXB5 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 3215 HGNC: 5116 AceView: HOXB5 Ensembl:ENSG00000120075 euGenes: HUgn3215
    ECgene: HOXB5 H-InvDB: HOXB5

    Other Databases showing HOXB5 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing HOXB5 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HOXB5 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for HOXB5 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for HOXB5 gene:
    Search GeneIP for patents involving HOXB5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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