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HOXB5 Gene

protein-coding   GIFtS: 55
GCID: GC17M046668

Homeobox B5

(Previous name: homeo box B5)
(Previous symbols: HOX2, HOX2A)
  See HOXB5-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Homeobox B51 2     Homeobox Protein Hu-12 3
HOX2A1 2 3 5     HHO.C102
HOX21 2     HU-12
Homeo Box B51 2     Hox2.12
Homeobox Protein HHO.C102 3     Homeo Box 2A2
Homeobox Protein Hox-2A2 3     Homeobox Protein Hox-B52

External Ids:    HGNC: 51161   Entrez Gene: 32152   Ensembl: ENSG000001200757   OMIM: 1429605   UniProtKB: P090673   

Export aliases for HOXB5 gene to outside databases

Previous GC identifers: GC17M046379 GC17M049149 GC17M047010 GC17M047143 GC17M044023 GC17M042037


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for HOXB5 Gene:
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding
domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions
as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of
this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of
bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue. (provided by
RefSeq, Jul 2008)

GeneCards Summary for HOXB5 Gene:
HOXB5 (homeobox B5) is a protein-coding gene. Diseases associated with HOXB5 include gastroschisis, and oral squamous cell carcinoma. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is HOXA7.

UniProtKB/Swiss-Prot: HXB5_HUMAN, P09067
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides
cells with specific positional identities on the anterior-posterior axis

Gene Wiki entry for HOXB5 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NC_018928.2  NT_010783.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the HOXB5 gene promoter:
         E2F-4   AP-1   AML1a   ATF-2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHOXB5 promoter sequence
   Search Chromatin IP Primers for HOXB5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HOXB5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.3   Ensembl cytogenetic band:  17q21.32   HGNC cytogenetic band: 17q21.32

HOXB5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HOXB5 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M046668:  view genomic region     (about GC identifiers)

Start:
46,668,619 bp from pter      End:
46,671,323 bp from pter
Size:
2,705 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: HXB5_HUMAN, P09067 (See protein sequence)
Recommended Name: Homeobox protein Hox-B5  
Size: 269 amino acids; 29434 Da
Developmental stage: Embryo
Sequence caution: Sequence=AAA52681.1; Type=Erroneous initiation;
Secondary accessions: B2RC69 P09069 Q17RP4

Explore the universe of human proteins at neXtProt for HOXB5: NX_P09067

Explore proteomics data for HOXB5 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys211
  • Modification sites at PhosphoSitePlus

  • See HOXB5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_002138.1  
    ENSEMBL proteins: 
     ENSP00000239151  

    HOXB5 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    HOXL: Homeoboxes / ANTP class : HOXL subclass

    Selected InterPro protein domains (see all 6):
     IPR001827 Homeobox_Antennapedia_CS
     IPR020479 Homeobox_metazoa
     IPR017995 Homeobox_antennapedia
     IPR017970 Homeobox_CS
     IPR001356 Homeobox_dom

    Graphical View of Domain Structure for InterPro Entry P09067

    ProtoNet protein and cluster: P09067

    1 Blocks protein domain: IPB001827 Homeobox protein

    UniProtKB/Swiss-Prot: HXB5_HUMAN, P09067
    Similarity: Belongs to the Antp homeobox family
    Similarity: Contains 1 homeobox DNA-binding domain


    Find genes that share domains with HOXB5           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HXB5_HUMAN, P09067
    Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides
    cells with specific positional identities on the anterior-posterior axis

         Genatlas biochemistry entry for HOXB5:
    homeo box B5(2A),homologous to mouse Hox-2.1,Drosophila Scr,involved in the positioning of the mouse upper limb
    bud

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding IEA--
    GO:0001205RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription IEA--
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity ----
    GO:0043565sequence-specific DNA binding ----
         
    Find genes that share ontologies with HOXB5           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for HOXB5:
     Increased gamma-H2AX phosphory  Synthetic lethal with Ras 

         3 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Hoxb5):
     nervous system  no phenotypic analysis  skeleton 

    Find genes that share phenotypes with HOXB5           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Hoxb5tm1Mrc for HOXB5

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HOXB5
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HOXB5

    miRNA
    Products:
        
    miRTarBase miRNAs that target HOXB5:
    hsa-mir-429 (MIRT016641), hsa-mir-141-3p (MIRT021658), hsa-mir-7-5p (MIRT006902), hsa-mir-200c-3p (MIRT021075), hsa-mir-200a-3p (MIRT020354), hsa-mir-200b-3p (MIRT024129)

    Block miRNA regulation of human, mouse, rat HOXB5 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HOXB5 (see all 20):
    hsa-miR-1260b hsa-miR-200a hsa-miR-944 hsa-miR-340 hsa-miR-4267 hsa-miR-141 hsa-miR-7-1* hsa-miR-23a
    SwitchGear 3'UTR luciferase reporter plasmidHOXB5 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat HOXB5

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    HXB5_HUMAN, P09067: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    Find genes that share ontologies with HOXB5           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including HOXB5: 
              Stem Cell Transcription Factors in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for HOXB5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 24)

    Selected Interacting proteins for HOXB5 (P090673 ENSP000002391514) via UniProtKB, MINT, STRING, and/or I2D (see all 24)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    PBX3P404263, ENSP000003625884I2D: score=1 STRING: ENSP00000362588
    HOXA2ENSP000002227184STRING: ENSP00000222718
    HOXB7ENSP000002391654STRING: ENSP00000239165
    CBX8ENSP000002693854STRING: ENSP00000269385
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated ----
    GO:0006355regulation of transcription, DNA-templated ----
    GO:0009653anatomical structure morphogenesis TAS3000607
    GO:0009952anterior/posterior pattern specification IEA--
    GO:0045446endothelial cell differentiation IEA--

    Find genes that share ontologies with HOXB5           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HOXB5 (HXB5)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for HOXB5 gene: 
    NM_002147.3  

    Unigene Cluster for HOXB5:

    Homeobox B5
    Hs.654456  [show with all ESTs]
    Unigene Representative Sequence: M92299
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000239151(uc002inr.3)
    miRNA
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    Block miRNA regulation of human, mouse, rat HOXB5 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HOXB5 (see all 20):
    hsa-miR-1260b hsa-miR-200a hsa-miR-944 hsa-miR-340 hsa-miR-4267 hsa-miR-141 hsa-miR-7-1* hsa-miR-23a
    SwitchGear 3'UTR luciferase reporter plasmidHOXB5 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat HOXB5
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HOXB5
    Addgene plasmids for HOXB5 
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    OriGene qPCR primer pairs and template standards for HOXB5
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      QuantiTect SYBR Green Assays in human, mouse, rat HOXB5
      QuantiFast Probe-based Assays in human, mouse, rat HOXB5

    Additional mRNA sequence: 

    AK314964.1 BC004454.1 BC008940.2 BC117247.1 M86726.1 M92299.1 X03794.1 

    3 DOTS entries:

    DT.92434272  DT.411060  DT.70102337 

    Selected AceView cDNA sequences (see all 63):

    BM994836 AW138080 BQ001097 BF063905 AI970004 BF516082 AI052747 BE905057 
    BF222398 BC008940 AA576890 BE793940 BI766494 BE797469 BX106448 AI761878 
    M92299 M86726 BC004454 AW973515 AI420155 BM797039 CB991412 AI281340 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HOXB5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGTCTGGCTA
    HOXB5 Expression
    About this image


    HOXB5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 13) fully expand
     
     Tendon & Ligament
             Cervical Sclerotome Cells Cervical Mesenchymal Sclerotome
     
     Bone (Muscoskeletal System)
             Cervical Sclerotome Cells Cervical Mesenchymal Sclerotome
     
     Cartilage (Muscoskeletal System)
             Cervical Sclerotome Cells Cervical Mesenchymal Sclerotome
     
     Somite (Muscoskeletal System)
             Cervical Sclerotome Cells Cervical Mesenchymal Sclerotome
     
     NULL (Uncategorized)
             Neural rosettes
    HOXB5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HOXB5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.654456

    UniProtKB/Swiss-Prot: HXB5_HUMAN, P09067
    Tissue specificity: Spinal cord

        Pathway & Disease-focused RT2 Profiler PCR Array including HOXB5: 
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HOXB5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for HOXB5 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hoxb51 , 5 homeobox B51, 5 94.67(n)1
    98.88(a)1
      11 (59.82 cM)5
    154131  NM_008268.21  NP_032294.21 
     963025955 
    chicken
    (Gallus gallus)
    Aves HOXB51 homeobox B5 77.27(n)
    81.82(a)
      425096  NM_001025355.1  NP_001020526.1 
    lizard
    (Anolis carolinensis)
    Reptilia HOXB56
    homeobox B5
    76(a)
    1 ↔ 1
    6(75593542-75596979)
    African clawed frog
    (Xenopus laevis)
    Amphibia hoxb5-A2 homeo box B5 80.06(n)    X07104.1 
    zebrafish
    (Danio rerio)
    Actinopterygii hoxb5a2 homeo box B5a 79.34(n)   30317  NM_131101.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Scr3 midgut development specific RNA
    polymerase II more
    73(a)   3 84A5   --


    ENSEMBL Gene Tree for HOXB5 (if available)
    TreeFam Gene Tree for HOXB5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HOXB5 gene
    HOXA72  HOXC62  HOXC52  HOXB42  HOXA52  ENSG000002732662  HOXA42  HOXC82  
    HOXA62  ENSG000002730492  HOXD82  HOXB62  HOXB82  HOXD42  HOXB72  HOXC42  
    10 SIMAP similar genes for HOXB5 using alignment to 1 protein entry:     HXB5_HUMAN:
    HOXC6    HOXA4    HOXA5    HOXB4    HOXD8    HOXC4
    HOXA7    HOXB7    HOXC5    HOXD4

    Find genes that share paralogs with HOXB5           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for HOXB5:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv833469CNV Loss17160897
    dgv3222n71CNV Loss21882294
    dgv3223n71CNV Loss21882294
    dgv369n27CNV Loss19166990
    dgv3224n71CNV Loss21882294
    nsv833471CNV Gain17160897
    dgv988e1CNV Complex17122850

    Human Gene Mutation Database (HGMD): HOXB5
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing HOXB5
    DNA2.0 Custom Variant and Variant Library Synthesis for HOXB5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 142960    OMIM disorders: --

    4 diseases for HOXB5:    
    About MalaCards
    gastroschisis    oral squamous cell carcinoma    myeloid leukemia    acute myeloid leukemia

    1 disease from the University of Copenhagen DISEASES database for HOXB5:
    Gastroschisis

    Find genes that share disorders with HOXB5           About GenesLikeMe

    Genetic Association Database (GAD): HOXB5

    Export disorders for HOXB5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HOXB5 gene, integrated from 10 sources (see all 37):
    (articles sorted by number of sources associating them with HOXB5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A genome-wide association meta-analysis identifies new childhood obesity loci. (PubMed id 22484627)1, 4 Bradfield J.P....Grant S.F. (Nat. Genet. 2012)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Cooperative DNA binding of the highly conserved human Hox 2.1 homeodomain gene product. (PubMed id 1355360)1, 2 Galang C.K. and Hauser C.A. (New Biol. 1992)
    4. Vertebrate homeobox gene nomenclature. (PubMed id 1358459)1, 3 Scott M.P. (Cell 1992)
    5. Nomenclature for human homeobox genes. (PubMed id 1973146)1, 3 McAlpine P.J. and Shows T.B. (Genomics 1990)
    6. Organization of human class I homeobox genes. (PubMed id 2576652)1, 2 Boncinelli E.... Simeone A. (Genome 1989)
    7. A human homoeo box gene specifically expressed in spinal cord during embryonic development. (PubMed id 3453105)1, 2 Simeone A.... Peschle C. (Nature 1986)
    8. Expression of homologous homeo-box-containing genes in differentiated human teratocarcinoma cells and mouse embryos. (PubMed id 4075393)1, 2 Hauser C.A....Tjian R. (Cell 1985)
    9. Human DNA sequences homologous to a protein coding region conserved between homeotic genes of Drosophila. (PubMed id 6091895)1, 2 Levine M.... Tjian R. (Cell 1984)
    10. Expression of Hoxb-5 during human lung development and in congenital lung malformations. (PubMed id 14632303)1, 9 Volpe M.V....Nielsen H.C. (Birth Defects Res. Part A Clin. Mol. Teratol. 2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 3215 HGNC: 5116 AceView: HOXB5 Ensembl:ENSG00000120075 euGenes: HUgn3215
    ECgene: HOXB5 H-InvDB: HOXB5

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HOXB5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for HOXB5 gene:
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