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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HOXB3 Gene

protein-coding   GIFtS: 52
GCID: GC17M046626

homeobox B3

(Previous name: homeo box B3 )
(Previous symbols: HOX2, HOX2G)
 Explore 14 diseases affiliated with
HOXB3 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for HOXB3    

Aliases
for HOXB3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Homeobox B31 2     Homeobox Protein Hox-2G2 3
HOX2G1 2 3 5     Hox-2.72
HOX21 2     Homeo Box 2G2
Homeo Box B31 2     Homeobox Protein Hox-B32
Homeobox Protein Hox-2.72 3     

External Ids:    HGNC: 51141   Entrez Gene: 32132   Ensembl: ENSG000001200937   OMIM: 1429665   UniProtKB: P146513   

Export aliases for HOXB3 gene to outside databases

Previous GC identifers: GC17M046338 GC17M049107 GC17M046969 GC17M047101 GC17M043983 GC17M041996


Summaries
for HOXB3 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for HOXB3:
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It
is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a
sequence-specific transcription factor that is involved in development. Increased expression of this gene is
associated with a distinct biologic subset of acute myeloid leukemia (AML). (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: HXB3_HUMAN, P14651
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells
with specific positional identities on the anterior-posterior axis

Gene Wiki entry for HOXB3


Genomic Views
for HOXB3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010783.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HOXB3 gene promoter:
         E2F-3a   E2F-4   E2F-5   E2F-1   ATF-2   E2F-2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: HOXB3 promoter sequence
   Search SABiosciences Chromatin IP Primers for HOXB3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HOXB3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.3   Ensembl cytogenetic band:  17q21.32   HGNC cytogenetic band: 17q21.32

HOXB3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HOXB3 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M046626:  view genomic region     (about GC identifiers)

Start:
 46,626,232 bp from pter      End:
 46,682,274 bp from pter
Size:
 56,043 bases      Orientation:
 minus strand

Proteins
for HOXB3 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: HXB3_HUMAN, P14651 (See protein sequence)
Recommended Name: Homeobox protein Hox-B3  
Size: 431 amino acids; 44340 Da
Subcellular location: Nucleus
Developmental stage: Expressed in whole embryos and fetuses at 5-9 weeks from conception
Secondary accessions: A8K567 D3DTV3 O95615 P17484

Explore the universe of human proteins at neXtProt for HOXB3: NX_P14651

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P14651

    • HOXB3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_002137.4  
    ENSEMBL proteins: 
     ENSP00000417207   ENSP00000419676   ENSP00000308252   ENSP00000420595   ENSP00000449977  
     ENSP00000418035   ENSP00000418729   ENSP00000418892   ENSP00000417400   ENSP00000446783  
     ENSP00000438747  

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    Novus Biologicals HOXB3 Protein
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for HOXB3

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--


    HOXB3 for ontologies           About GeneDecksing



    HOXB3 Antibody Products: 
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    Uscn ELISAs and CLIAs for HOXB3

    Protein Domains /
    Families
    for HOXB3 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HOXB3 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR001827 Homeobox_Antennapedia_CS
     IPR020479 Homeobox_metazoa
     IPR017970 Homeobox_CS
     IPR001356 Homeodomain
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry P14651

    ProtoNet protein and cluster: P14651

    2 Blocks protein families:
    IPB000047 Lambda and other repressor helix-turn-helix signature
    IPB001827 Homeobox protein


    UniProtKB/Swiss-Prot: HXB3_HUMAN, P14651
    Similarity: Belongs to the Antp homeobox family
    Similarity: Contains 1 homeobox DNA-binding domain


    Function
    for HOXB3 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: HXB3_HUMAN, P14651
    Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells
    with specific positional identities on the anterior-posterior axis

         Genatlas biochemistry entry for HOXB3:
    homeo box B3(2G),homologous to mouse Hox-2.7,Drosophila Zen

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HOXB3
    8/79 QIAGEN miScript miRNA Assays for microRNAs that regulate HOXB3 (see all 79):
    hsa-miR-548j hsa-miR-520e hsa-miR-607 hsa-miR-4272 hsa-miR-374a hsa-miR-519a hsa-miR-3161 hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmid: HOXB3 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HOXB3 (see all 7)
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    Gene Editing
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    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for HOXB3

    In Situ Assay
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000979RNA polymerase II core promoter sequence-specific DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0043565sequence-specific DNA binding ----


    HOXB3 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for HOXB3:
     Wnt reporter downregulated 

    Animal Models:
         Mouse knock-out Hoxb3tm1Mrc for HOXB3
         10 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Hoxb3):
     craniofacial  embryogenesis  endocrine/exocrine gland  hematopoietic system  immune system 
     mortality/aging  nervous system  normal  respiratory system  skeleton 

    HOXB3 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for HOXB3 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HOXB3

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for HOXB3 (P146513 ENSP000003082524) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HMGB1P094293, ENSP000003430404I2D: score=1 STRING: ENSP00000343040
    CREBBPQ927933, ENSP000002623674I2D: score=2 STRING: ENSP00000262367
    EP300Q094723, ENSP000002632534I2D: score=1 STRING: ENSP00000263253
    About this table

    Gene Ontology (GO): 5/12 biological process terms (GO ID links to tree view) (see all 12):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IEA--
    GO:0001525angiogenesis IEP17972163
    GO:0006351transcription, DNA-dependent IEA--
    GO:0009952anterior/posterior pattern specification IEA--
    GO:0021546rhombomere development IEA--


    HOXB3 for ontologies           About GeneDecksing



    Drugs & Compounds
    for HOXB3 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HOXB3
    Search CenterWatch for drugs/clinical trials and news about HOXB3 / HXB3 

    Transcripts
    for HOXB3 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for HOXB3 gene: 
    NM_002146.4  

    Unigene Cluster for HOXB3:

    Homeobox B3
    Hs.654560  [show with all ESTs]
    Unigene Representative Sequence: NM_002146
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000470495(uc002inn.3 uc002ino.3 uc010wlk.2 uc010wll.2 uc010wlm.2 uc010dbf.3 uc010dbg.3)
    ENST00000472863 ENST00000311626 ENST00000498678 ENST00000490677 ENST00000460160
    ENST00000489475 ENST00000476342 ENST00000471459 ENST00000465120 ENST00000478644
    ENST00000464266 ENST00000552000 ENST00000485909

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HOXB3
    8/79 QIAGEN miScript miRNA Assays for microRNAs that regulate HOXB3 (see all 79):
    hsa-miR-548j hsa-miR-520e hsa-miR-607 hsa-miR-4272 hsa-miR-374a hsa-miR-519a hsa-miR-3161 hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmid: HOXB3 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HOXB3 (see all 7)
    OriGene shRNA RFP: HOXB3
    OriGene siRNA: HOXB3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HOXB3
    Clone
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    GenScript: all cDNA clones in your preferred vector: HOXB3 (NM_002146)
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HOXB3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HOXB3

    Additional cDNA sequence: 

    AK027609.1 AK291182.1 AK299226.1 AK299265.1 AK309721.1 AK315102.1 AK316245.1 X16667.1 

    8 DOTS entries:

    DT.40118139  DT.120919415  DT.435198  DT.95097958  DT.120919433  DT.204604  DT.40126964  DT.91805018 

    21 AceView cDNA sequences:

    BU179121 BE676812 AA952925 AA303036 AA303037 NM_002146 AI702564 CD517099 
    BE349975 AW135928 U59298 AI215090 AK027609 AI554404 X16667 AI739053 
    BX103550 AA301768 AI684087 AI796199 BQ027917 

    GeneLoc Exon Structure


    Expression
    for HOXB3 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HOXB3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AACTCAGCTC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    HOXB3 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    9 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Head MesenchymeBranchial Arch 3,4,6Cardiac Neural Crest CellsNeural Crest
    Lateral Plate MesodermEmbryonic Blood IslandsAngioblastsEndothelium
    Lateral Plate MesodermEmbryonic Capillary PlexusAngioblastsEndothelium
    Lateral Plate MesodermProepicardiumAngioblastsEndothelium
    LungLung MesodermDistal Mesodermal Progenitor CellsLung
    LungLung MesodermProximal Mesodermal Progenitor CellsLung
    Neural TubeNeural TubeSpinal Neural Tube CellsNeural Ectoderm
    BrainMedulla OblongataBrain
    Spinal CordPresumptive Spinal CordSpinal Cord
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 4 LifeMap Cells 
    NameCategory
    PureStem™ progenitor RASMO12 (Embryonic Progenitor Cell)
    PureStem™ progenitor W10 (Embryonic Progenitor Cell)
    Posterior foregut-like cells (A scalable, suspensi...)
    Beating cell clusters (Spontaneous differen...)

    See HOXB3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HOXB3

    SOURCE GeneReport for Unigene cluster: Hs.654560
        SABiosciences Expression via Pathway-Focused PCR Arrays including HOXB3: 
              Stem Cell Transcription Factors in human mouse rat
              Homeobox (HOX) Genes in human mouse rat

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    In Situ
    Assay Products:     
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    Orthologs
    for HOXB3 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for HOXB3 gene from 4/15 species (see all 15)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves HOXB31 homeobox B3 72.17(n)
    70.81(a)    		   395502  NM_204743.1  NP_990074.1 
    lizard
    (Anolis carolinensis)    		 Reptilia HOXB36
    		 --
    		 64(a)
    		 1 ↔ 1
    		 6(75513232-75520712)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia Str.154502 Transcribed sequence with weak similarity to protein more 79.53(n)    CF150160.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii hoxb3a2 homeo box B3a 73.38(n)   30339  AJ537509.1 


    ENSEMBL Gene Tree for HOXB3 (if available)
    TreeFam Gene Tree for HOXB3 (if available) 

    Paralogs
    for HOXB3 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HOXB3 gene
    GSX12  HOXA72  HOXA12  HOXD12  HOXA22  HOXC62  HOXB52  GSX22  
    HOXC52  HOXB42  HOXA52  HOXA42  HOXD32  HOXC82  HOXA62  HOXA32  
    HOXD82  HOXB12  HOXB62  HOXB82  HOXD42  HOXB22  HOXB72  PDX12  
    HOXC42  
    12 SIMAP similar genes for HOXB3 using alignment to 6 protein entries:     HXB3_HUMAN (see all proteins):
    HOX B6    HOXD8    HOXC13    HOXA3    HLX    HOXA4
    HOXD3    NKX2-5    MEOX1    HOXD11    MNX1    HOXB1

    HOXB3 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for HOXB3
    PGOHUM00000240692


    Genomic Variants
    for HOXB3 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/424 NCBI SNPs in HOXB3 are shown (see all 424)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 17 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1381456591,2
    		--46625806(+) AAGTTG/TAGGTT 1 -- ds50010--------
    rs1919290861,2
    		--46625886(+) ATGGAA/CGCTGT 1 -- ds50010--------
    rs1840734961,2
    		--46625888(+) GGACGC/TTGTGG 1 -- ds50010--------
    rs1495452791,2
    		--46625988(+) TCCCCC/TGTTAC 1 -- ds50010--------
    rs1163251321,2
    		F,--46626052(+) CTCTTA/GTGAGT 1 -- ds50011Minor allele frequency- G:0.03WA 118
    rs1884095621,2
    		--46626078(+) AAACTG/TAAGAC 1 -- ds50010--------
    rs1452263551,2
    		C,--46626117(+) TGGAC-/AAAAAA 1 -- ds50010--------
    rs1807316561,2
    		--46626373(+) AGTGAC/TGATTA 1 -- ut310--------
    rs1441057161,2
    		--46626454(+) CTCTTC/TTCTAG 1 -- ut310--------
    rs728298471,2
    		C,F,--46626484(+) TAGCTG/AGTTTT 1 -- ut311Minor allele frequency- A:0.06NA 120

    HapMap Linkage Disequilibrium report for HOXB3 (46626232 - 46682274 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for HOXB3
         3 CNVs: 53230 4040 77654

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    Disorders / Diseases
    for HOXB3 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    HOXB3 for disorders           About GeneDecksing

    OMIM gene information: 142966    OMIM disorders: --

    14 diseases for HOXB3:    About MalaCards
    acute myeloid leukemia    myeloid leukemia    leukemia    vacterl association
    acute lymphoblastic leukemia    esophageal atresia    lymphoblastic leukemia    embryonal carcinoma
    hematopoiesis    pancreatic cancer    pancreatitis    esophagitis
    thyroiditis    carcinoma

    1 disease from the University of Copenhagen DISEASES database for HOXB3:
    VACTERL association

    1 Novoseek disease relationship for HOXB3 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    leukemia 8.36 1 11113197 (1)


    Export disorders for HOXB3 gene to outside databases

    Publications
    for HOXB3 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HOXB3 gene, integrated from 9 sources (see all 37):
    (articles sorted by number of sources associating them with HOXB3)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    2. Vertebrate homeobox gene nomenclature. (PubMed id 1358459)1, 3 Scott M.P. (1992)
    3. Nomenclature for human homeobox genes. (PubMed id 1973146)1, 3 McAlpine P.J. and Shows T.B. (1990)
    4. The human HOX gene family. (PubMed id 2574852)1, 2 Acampora D.... Boncinelli E. (1989)
    5. Differential expression of human HOX-2 genes along the anterior- posterior axis in embryonic central nervous system. (PubMed id 2570724)1, 2 Giampaolo A.... Peschle C. (1989)
    6. Organization of human class I homeobox genes. (PubMed id 2576652)1, 2 Boncinelli E.... Simeone A. (1989)
    7. Regulatory interactions between the human HOXB1, HOXB2, and HOXB3 proteins and the upstream sequence of the Otx2 gene in embryonal carcinoma cells. (PubMed id 9556594)1, 9 Guazzi S....Boncinelli E. (1998)
    8. Epigenetic silencing of the RASSF1A tumor suppressor gene through HOXB3-mediated induction of DNMT3B expression. (PubMed id 19854132)1, 9 Palakurthy R.K....Green M.R. (2009)
    9. HOX gene analysis of endothelial cell differentiation in human bone marrow-derived mesenchymal stem cells. (PubMed id 17972163)1, 9 Chung N....Rha H.K. (2009)
    10. The thyroid transcription factor-1 gene is a candidate target for regulation by Hox proteins. (PubMed id 7913891)1, 9 Guazzi S....Mavilio F. (1994)

    External Searches for HOXB3 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing HOXB3 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 3213 HGNC: 5114 AceView: HOXB3 Ensembl:ENSG00000120093 euGenes: HUgn3213
    ECgene: HOXB3 H-InvDB: HOXB3

    Other Databases showing HOXB3 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing HOXB3 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HOXB3 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for HOXB3 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for HOXB3 gene:
    Search GeneIP for patents involving HOXB3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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