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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HOXB13 Gene

protein-coding   GIFtS: 58
GCID: GC17M046802

Homeobox B13

(Previous name: homeo box B13)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Homeobox B131 2
Homeo Box B131
PSGD2
Homeobox Protein Hox-B132

External Ids:    HGNC: 51121   Entrez Gene: 104812   Ensembl: ENSG000001591847   OMIM: 6046075   UniProtKB: Q928263   

Export aliases for HOXB13 gene to outside databases

Previous GC identifers: GC17M046514 GC17M049284 GC17M047145 GC17M047278 GC17M044158 GC17M042171


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for HOXB13 Gene:
This gene encodes a transcription factor that belongs to the homeobox gene family. Genes of this family are highly
conserved among vertebrates and essential for vertebrate embryonic development. This gene has been implicated to
play a role in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit
temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary
axes, which suggests functions in body patterning along the axis. This gene and other HOXB genes form a gene
cluster at chromosome the 17q21-22 region. (provided by RefSeq, Jul 2008)

GeneCards Summary for HOXB13 Gene: 
HOXB13 (homeobox B13) is a protein-coding gene. Diseases associated with HOXB13 include myxopapillary ependymoma, and spinal cord ependymoma. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is HOXD11.

UniProtKB/Swiss-Prot: HXB13_HUMAN, Q92826
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides
cells with specific positional identities on the anterior-posterior axis

Gene Wiki entry for HOXB13 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.2  NT_010783.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HOXB13 gene promoter:
         AML1a   p53   LUN-1   Evi-1   MEF-2A   AREB6   PPAR-gamma1   PPAR-gamma2   aMEF-2   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHOXB13 promoter sequence
   Search SABiosciences Chromatin IP Primers for HOXB13

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HOXB13


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.2   Ensembl cytogenetic band:  17q21.32   HGNC cytogenetic band: 17q21.32

HOXB13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HOXB13 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M046802:  view genomic region     (about GC identifiers)

Start:
46,802,125 bp from pter      End:
46,806,540 bp from pter
Size:
4,416 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: HXB13_HUMAN, Q92826 (See protein sequence)
Recommended Name: Homeobox protein Hox-B13  
Size: 284 amino acids; 30676 Da
Subcellular location: Nucleus
1 PDB 3D structure from and Proteopedia for HOXB13:
2CRA (3D)    
Secondary accessions: B2R878 Q96QM4 Q99810

Explore the universe of human proteins at neXtProt for HOXB13: NX_Q92826

Explore proteomics data for HOXB13 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q92826

  • HOXB13 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    HOXB13 Protein Expression
    REFSEQ proteins: NP_006352.2  
    ENSEMBL proteins: 
     ENSP00000290295  

    Human Recombinant Protein Products for HOXB13: 
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    Novus Biologicals HOXB13 Proteins
    Novus Biologicals HOXB13 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for HOXB13 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005667transcription factor complex IEA--

    HOXB13 for ontologies           About GeneDecksing



    HOXB13 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    HOXL: Homeoboxes / ANTP class : HOXL subclass

    4 InterPro protein domains:
     IPR022067 HoxA13_N
     IPR017970 Homeobox_CS
     IPR001356 Homeodomain
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry Q92826

    ProtoNet protein and cluster: Q92826

    UniProtKB/Swiss-Prot: HXB13_HUMAN, Q92826
    Similarity: Belongs to the Abd-B homeobox family
    Similarity: Contains 1 homeobox DNA-binding domain


    HOXB13 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HXB13_HUMAN, Q92826
    Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides
    cells with specific positional identities on the anterior-posterior axis

         Genatlas biochemistry entry for HOXB13:
    homeo box B13

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0005515protein binding ----
    GO:0043565sequence-specific DNA binding IEA--
         
    HOXB13 for ontologies           About GeneDecksing


    Phenotypes:
         9 MGI mutant phenotypes (inferred from 4 alleles(MGI details for Hoxb13):
     behavior/neurological  cellular  embryogenesis  endocrine/exocrine gland  integument 
     limbs/digits/tail  nervous system  reproductive system  skeleton 

    HOXB13 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for HOXB13: Hoxb13tm2Mrc Hoxb13tm4Mrc

       inGenious Targeting Laboratory - Custom generated mouse model solutions for HOXB13 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for HOXB13

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HOXB13 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HOXB13 

    miRNA
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    8/33 QIAGEN miScript miRNA Assays for microRNAs that regulate HOXB13 (see all 33):
    hsa-miR-520e hsa-miR-302d hsa-miR-1224-3p hsa-miR-106a hsa-miR-1260b hsa-miR-9 hsa-miR-372 hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidHOXB13 3' UTR sequence
    Inhib. RNA
    Products:
        
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                         Customized lentivirus expression plasmids for stable overexpression of HOXB13 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HOXB13


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for HOXB13 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Regulation of Androgen receptor activity
    Regulation of Androgen receptor activity


    1 BioSystems Pathway for HOXB13
        Regulation of Androgen receptor activity



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for HOXB13

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/9 Interacting proteins for HOXB13 (Q928263 ENSP000002902954) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ALX4Q9H1613, ENSP000003327444I2D: score=2 STRING: ENSP00000332744
    MEIS1O004703, ENSP000002723694I2D: score=2 STRING: ENSP00000272369
    HOXD4P090163, ENSP000003025484I2D: score=1 STRING: ENSP00000302548
    POU2F1P148593, ENSP000002714114I2D: score=1 STRING: ENSP00000271411
    IRF4Q153063, ENSP000003703434I2D: score=1 STRING: ENSP00000370343
    About this table

    Gene Ontology (GO): 10 biological process terms (GO ID links to tree view) (see first 5):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001525angiogenesis IEP17972163
    GO:0002009morphogenesis of an epithelium ----
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0008544epidermis development TAS9665387
    GO:0009611response to wounding TAS9665387
    GO:0033574response to testosterone stimulus IEA--
    GO:0040008regulation of growth IEA--
    GO:0060527prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis IEA--
    GO:0060743epithelial cell maturation involved in prostate gland development IEA--

    HOXB13 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HOXB13 (HXB13)

    Search CenterWatch for drugs/clinical trials and news about HOXB13 / HXB13

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for HOXB13 gene: 
    NM_006361.5  

    Unigene Cluster for HOXB13:

    Homeobox B13
    Hs.66731  [show with all ESTs]
    Unigene Representative Sequence: AY937237
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000290295(uc002ioa.3)
    miRNA
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    8/33 QIAGEN miScript miRNA Assays for microRNAs that regulate HOXB13 (see all 33):
    hsa-miR-520e hsa-miR-302d hsa-miR-1224-3p hsa-miR-106a hsa-miR-1260b hsa-miR-9 hsa-miR-372 hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidHOXB13 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for HOXB13
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HOXB13
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HOXB13
    Sirion Biotech Customized lentivirus for stable overexpression of HOXB13 
                         Customized lentivirus expression plasmids for stable overexpression of HOXB13 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HOXB13
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HOXB13

    Additional mRNA sequence: 

    AK225234.1 AK313266.1 AY937237.1 BC007092.1 BC070233.1 BT007410.1 U57052.1 U81599.1 

    4 DOTS entries:

    DT.113856  DT.120986724  DT.121625890  DT.91754878 

    24/118 AceView cDNA sequences (see all 118):

    CB050115 AI420106 AA628095 BF447097 AI686226 BX090775 BF222357 BE388501 
    BF057410 BE645544 BE859056 BF062550 BC007092 AI669295 BF589565 AI655923 
    AI620785 AI378797 BQ673782 BC070233 AI804883 BE858992 CB050884 AI700363 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HOXB13 expression in normal human tissues (normalized intensities)      HOXB13 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTCTAACTCC
    HOXB13 Expression
    About this image


    HOXB13 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Colon (Gastrointestinal Tract)    fully expand to see all 2 entries
             rectum ; glandular cells   
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Spinal Ventral Columns
     
     Prostate (Endocrine System)
             prostate ; glandular cells   
     
     Gut Tube (Gastrointestinal Tract)
             Hindgut
     
     Lower Urinary Tract (Urinary System)
             visceral organ/urogenital sinus/urethra   

    See HOXB13 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HOXB13

    SOURCE GeneReport for Unigene cluster: Hs.66731
        SABiosciences Expression via Pathway-Focused PCR Arrays including HOXB13: 
              Stem Cell Transcription Factors in human mouse rat
              Homeobox (HOX) Genes in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HOXB13

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for HOXB13 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hoxb131 , 5 homeobox B131, 5 87.56(n)1
    93.66(a)1
      11 (59.63 cM)5
    154081  NM_008267.31  NP_032293.11 
     961943165 
    chicken
    (Gallus gallus)
    Aves HOXB131 homeobox B13 67.18(n)
    63.18(a)
      771676  XM_001234926.1  XP_001234927.1 
    lizard
    (Anolis carolinensis)
    Reptilia HOXB136
    Uncharacterized protein
    72(a)
    1 ↔ 1
    6(75781126-75781712)
    zebrafish
    (Danio rerio)
    Actinopterygii hoxb13a1 homeo box B13a 64.31(n)
    66.17(a)
      559921  NM_001044912.1  NP_001038377.1 


    ENSEMBL Gene Tree for HOXB13 (if available)
    TreeFam Gene Tree for HOXB13 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HOXB13 gene
    HOXD112  ENSG000002571842  HOXD102  HOXC132  HOXC102  HOXD122  HOXA92  HOXA132  
    HOXC92  HOXC122  HOXC112  HOXD132  HOXA112  HOXB92  HOXD92  HOXA102  
    6 SIMAP similar genes for HOXB13 using alignment to 2 protein entries:     HXB13_HUMAN (see all proteins):
    HOXC13    HOXA4    HOXB1    HOX B6    HOXA13    HOXD13

    HOXB13 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/103 SNPs in HOXB13 are shown (see all 103)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs22803531,2
    C,F,H--46803851(-) TGATCG/ATTAGC 1 -- ut31 ese35Minor allele frequency- A:0.00NS EA 536
    rs1922444271,2
    --46803939(+) CCCTGC/GTGGAG 1 -- ut310--------
    rs1836209201,2
    --46804037(+) AAGGGC/TGTTGT 1 -- ut310--------
    rs1874428391,2
    --46804081(+) AGCCTG/TGGCTT 1 -- ut310--------
    rs1411795921,2
    --46804095(+) AGGTTC/TCTGGT 1 -- ut310--------
    rs1449675041,2
    --46804098(+) TTCCTC/GGTCTC 1 -- ut310--------
    rs771798531,2
    C--46804154(+) TCTTA-/AGGGGT 2 K * fra10--------
    rs2009973841,2
    C--46804175(+) CTTCAA/CCTTGG 2 V L mis10--------
    rs1918869301,2
    C--46804181(+) CTTGGC/TGAGAA 2 T A mis10--------
    rs1386751881,2
    C,F--46804272(+) CGCCTC/TTTGTC 2 K syn11Minor allele frequency- T:0.00NA 4552

    HapMap Linkage Disequilibrium report for HOXB13 (46802125 - 46806540 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for HOXB13:    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv988e1CNV Complex17122850


    Human Gene Mutation Database (HGMD): HOXB13
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing HOXB13
    DNA2.0 Custom Variant and Variant Library Synthesis for HOXB13

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 604607    OMIM disorders: --

    14 diseases for HOXB13:    About MalaCards
    myxopapillary ependymoma    spinal cord ependymoma    ependymoma    phyllode tumor
    cytochrome p450    renal cell carcinoma    cervicitis    colorectal cancer
    ovarian cancer    prostate cancer    melanoma    prostatitis
    endotheliitis    breast cancer

    2 diseases from the University of Copenhagen DISEASES database for HOXB13:
    Spinal cord ependymoma     Prostate cancer

    HOXB13 for disorders           About GeneDecksing

    Genetic Association Database (GAD): HOXB13
    Human Genome Epidemiology (HuGE) Navigator: HOXB13 (1 document)

    Export disorders for HOXB13 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HOXB13 gene, integrated from 9 sources (see all 52):
    (articles sorted by number of sources associating them with HOXB13)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Modulation of the human homeobox genes PRX-2 and HOXB13 in scarless fetal wounds. (PubMed id 9665387)1, 2, 3 Stelnicki E.J....Largman C. (1998)
    2. Hoxb-13: a new Hox gene in a distant region of the HOXB cluster maintains colinearity. (PubMed id 8756292)1, 2, 3 Zeltser L.M.... Heintz N. (1996)
    3. Cytochrome P450 2D6 and homeobox 13/interleukin-17B receptor: combining inherited and tumor gene markers for prediction of tamoxifen resistance. (PubMed id 18794098)1, 4 Goetz M.P....Ingle J.N. (2008)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete mutation analysis panel of the 39 human HOX genes. (PubMed id 11857506)1, 2 Kosaki K.... Matsuo N. (2002)
    6. Epigenetic repression of the estrogen-regulated Homeobox B13 gene in breast cancer. (PubMed id 18499701)1, 9 Rodriguez B.A....Huang T.H. (2008)
    7. HOXB13 homeodomain protein is cytoplasmic throughout fetal skin development. (PubMed id 12761847)1, 9 Komuves L.G....Largman C. (2003)
    8. Testing for the recurrent HOXB13 G84E germline mutatio n in men with clinical indications for prostate biopsy. (PubMed id 23036981)1 Schroeck F.R....Wei J.T. (2013)
    9. Regulation of DU145 prostate cancer cell growth by Scm -like with four mbt domains 2. (PubMed id 23385818)1 Lee K....Ju B.G. (2013)
    10. A novel germline mutation in HOXB13 is associated with prostate cancer risk in Chinese men. (PubMed id 22718278)1 Lin X....Xu J. (2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10481 HGNC: 5112 AceView: HOXB13 Ensembl:ENSG00000159184 euGenes: HUgn10481
    ECgene: HOXB13 H-InvDB: HOXB13

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HOXB13 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for HOXB13 gene:
    Search GeneIP for patents involving HOXB13

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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