Aliases for HOXA7 Gene
External Ids for HOXA7 Gene
Previous HGNC Symbols for HOXA7 Gene
Previous GeneCards Identifiers for HOXA7 Gene
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. For example, the encoded protein represses the transcription of differentiation-specific genes during keratinocyte proliferation, but this repression is then overcome by differentiation signals. This gene is highly similar to the antennapedia (Antp) gene of Drosophila. [provided by RefSeq, Jul 2008]
GeneCards Summary for HOXA7 Gene
HOXA7 (Homeobox A7) is a Protein Coding gene. Diseases associated with HOXA7 include Oculoauricular Syndrome and Leukemia, Acute Myeloid. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and transcription factor binding. An important paralog of this gene is HOXB7.
UniProtKB/Swiss-Prot for HOXA7 Gene
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.