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HOXA7 Gene

protein-coding   GIFtS: 55
GCID: GC07M027193

Homeobox A7

(Previous name: homeo box A7)
(Previous symbols: HOX1A, HOX1)
  See HOXA7-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Homeobox A71 2     Homeobox Protein Hox-1A2 3
HOX1A1 2 3 5     ANTP2
HOX11 2     HOX1.12
Homeo Box A71 2     Homeobox Protein Hox-A72
Homeobox Protein Hox 1.12 3     

External Ids:    HGNC: 51081   Entrez Gene: 32042   Ensembl: ENSG000001225927   OMIM: 1429505   UniProtKB: P312683   

Export aliases for HOXA7 gene to outside databases

Previous GC identifers: GC07M026836 GC07M026936 GC07M026967 GC07M027159


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for HOXA7 Gene:
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters
named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally
regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a
DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. For
example, the encoded protein represses the transcription of differentiation-specific genes during keratinocyte
proliferation, but this repression is then overcome by differentiation signals. This gene is highly similar to
the antennapedia (Antp) gene of Drosophila. (provided by RefSeq, Jul 2008)

GeneCards Summary for HOXA7 Gene:
HOXA7 (homeobox A7) is a protein-coding gene. Diseases associated with HOXA7 include acute leukemia, and acute promyelocytic leukemia. GO annotations related to this gene include transcription factor binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is HOXB5.

UniProtKB/Swiss-Prot: HXA7_HUMAN, P31268
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides
cells with specific positional identities on the anterior-posterior axis

Gene Wiki entry for HOXA7 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000007.13  NC_018918.2  NT_007819.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the HOXA7 gene promoter:
         CREB   Sp1   p53   deltaCREB   c-Myb   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): HOXA7 promoter sequence
   Search Chromatin IP Primers for HOXA7

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HOXA7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p15.2   Ensembl cytogenetic band:  7p15.2   HGNC cytogenetic band: 7p15.2

HOXA7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HOXA7 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M027193:  view genomic region     (about GC identifiers)

Start:
27,193,335 bp from pter      End:
27,197,555 bp from pter
Size:
4,221 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 27,244,510-27,247,471     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: HXA7_HUMAN, P31268 (See protein sequence)
Recommended Name: Homeobox protein Hox-A7  
Size: 230 amino acids; 25355 Da
Secondary accessions: A4D191 O43368 O43486 O95655 Q9NSC8 Q9UDM1

Explore the universe of human proteins at neXtProt for HOXA7: NX_P31268

Explore proteomics data for HOXA7 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys147
  • Modification sites at PhosphoSitePlus

  • See HOXA7 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_008827.2  
    ENSEMBL proteins: 
     ENSP00000242159   ENSP00000428563  

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    Cloud-Clone Corp. Proteins for HOXA7

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    HOXL: Homeoboxes / ANTP class : HOXL subclass

    Selected InterPro protein domains (see all 6):
     IPR001827 Homeobox_Antennapedia_CS
     IPR020479 Homeobox_metazoa
     IPR017995 Homeobox_antennapedia
     IPR017970 Homeobox_CS
     IPR001356 Homeobox_dom

    Graphical View of Domain Structure for InterPro Entry P31268

    ProtoNet protein and cluster: P31268

    1 Blocks protein domain: IPB001827 Homeobox protein

    UniProtKB/Swiss-Prot: HXA7_HUMAN, P31268
    Similarity: Belongs to the Antp homeobox family
    Similarity: Contains 1 homeobox DNA-binding domain


    Find genes that share domains with HOXA7           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HXA7_HUMAN, P31268
    Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides
    cells with specific positional identities on the anterior-posterior axis

         Genatlas biochemistry entry for HOXA7:
    homeo box A7(1A),homologous to mouse Hox-1.1,Drosophila Antp,Ubx,abd-A,expressed in erythroleukemic cell line

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0008134transcription factor binding IPI18973687
    GO:0043565sequence-specific DNA binding IDA11435435
         
    Find genes that share ontologies with HOXA7           About GenesLikeMe


    Phenotypes:
         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Hoxa7):
     hematopoietic system  immune system  normal  skeleton 

    Find genes that share phenotypes with HOXA7           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Hoxa7tm1Mrc for HOXA7

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HOXA7
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HOXA7
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HOXA7

    miRNA
    Products:
        
    miRTarBase miRNAs that target HOXA7:
    hsa-mir-196a-5p (MIRT002940), hsa-mir-423-5p (MIRT038144), hsa-mir-31-5p (MIRT049904)

    Block miRNA regulation of human, mouse, rat HOXA7 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HOXA7 (see all 27):
    hsa-miR-607 hsa-miR-3673 hsa-miR-185* hsa-miR-520d-5p hsa-miR-548v hsa-miR-221 hsa-miR-144 hsa-miR-199b-5p
    SwitchGear 3'UTR luciferase reporter plasmidHOXA7 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for HOXA7
    Predesigned siRNA for gene silencing in human, mouse, rat HOXA7

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    GenScript: all cDNA clones in your preferred vector: HOXA7 (NM_006896)
    Browse Sino Biological Human cDNA Clones
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    Addgene plasmids for HOXA7 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HOXA7


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    HXA7_HUMAN, P31268: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IC11435435

    Find genes that share ontologies with HOXA7           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Arrays including HOXA7: 
              Stem Cell Transcription Factors in human mouse rat
              Homeobox (HOX) Genes in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for HOXA7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 24)

    Selected Interacting proteins for HOXA7 (P312683 ENSP000002421594) via UniProtKB, MINT, STRING, and/or I2D (see all 25)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MEIS1O004703, ENSP000002723694I2D: score=1 STRING: ENSP00000272369
    MEN1O002553, ENSP000003370884I2D: score=1 STRING: ENSP00000337088
    GMNNO754963, ENSP000002300564I2D: score=4 STRING: ENSP00000230056
    KAT6AQ927943, ENSP000002657134I2D: score=1 STRING: ENSP00000265713
    PSIP1O754753, ENSP000003701094I2D: score=1 STRING: ENSP00000370109
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IDA11435435
    GO:0001525angiogenesis IEP17972163
    GO:0001953negative regulation of cell-matrix adhesion IDA14704364
    GO:0002686negative regulation of leukocyte migration IDA14704364
    GO:0006351transcription, DNA-templated IEA--

    Find genes that share ontologies with HOXA7           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HOXA7 (HXA7)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for HOXA7 gene: 
    NM_006896.3  

    Unigene Clusters for HOXA7:

    Homeobox A7
    Hs.610216  [show with all ESTs], Hs.660918  [show with all ESTs]
    Unigene Representative Sequences: NR_038831, AF026397
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000242159(uc003sys.3) ENST00000523796 ENST00000519842
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat HOXA7 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HOXA7 (see all 27):
    hsa-miR-607 hsa-miR-3673 hsa-miR-185* hsa-miR-520d-5p hsa-miR-548v hsa-miR-221 hsa-miR-144 hsa-miR-199b-5p
    SwitchGear 3'UTR luciferase reporter plasmidHOXA7 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for HOXA7
    Predesigned siRNA for gene silencing in human, mouse, rat HOXA7
    Clone
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    GenScript: all cDNA clones in your preferred vector: HOXA7 (NM_006896)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HOXA7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HOXA7
    Addgene plasmids for HOXA7 
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    OriGene qSTAR qPCR primer pairs in human, mouse for HOXA7
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat HOXA7
      QuantiTect SYBR Green Assays in human, mouse, rat HOXA7
      QuantiFast Probe-based Assays in human, mouse, rat HOXA7

    Additional mRNA sequence: 

    AF026397.1 BC061916.1 

    6 DOTS entries:

    DT.75101351  DT.121115444  DT.40253843  DT.99932800  DT.70100491  DT.40285593 

    Selected AceView cDNA sequences (see all 34):

    BE645526 AW470294 AI650267 AW450368 AK096334 AW450250 AI887912 AX747263 
    AK091933 AI660992 AA557521 AW205417 BF510786 AI492051 BF970710 AK092154 
    AI830321 AI762011 AA570160 BE146237 BE146039 H28870 AW292631 F37656 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HOXA7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGTGGAAGA
    HOXA7 Expression
    About this image


    HOXA7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Kidney (Urinary System)    fully expand to see all 2 entries
             mK4
     
     Motor Neurons (Nervous System)
             Motor neuron-like cells
     
     Neurons
             Motor neuron-like cells
     
     NULL (Uncategorized)
             CD31, CD144 positive cells
     
     Endothelium (Cardiovascular System)
             Human umbilical vein endothelial cells (HUVEC)
    HOXA7 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HOXA7 Protein Expression

    SOURCE GeneReport for Unigene clusters: Hs.610216 Hs.660918
        Pathway & Disease-focused RT2 Profiler PCR Arrays including HOXA7: 
              Stem Cell Transcription Factors in human mouse rat
              Homeobox (HOX) Genes in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HOXA7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for HOXA7 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hoxa71 , 5 homeobox A71, 5 92.17(n)1
    95(a)1
      6 (25.40 cM)5
    154041  NM_010455.21  NP_034585.11 
     522144915 
    chicken
    (Gallus gallus)
    Aves HOXA71 homeobox A7 81.65(n)
    86.36(a)
      395290  NM_204595.1  NP_989926.1 
    lizard
    (Anolis carolinensis)
    Reptilia HOXA76
    homeobox A7
    69(a)
    1 ↔ 1
    GL343275.1(1454822-1457870)
    African clawed frog
    (Xenopus laevis)
    Amphibia hox362 homeobox protein 77.93(n)    M24752.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Antp3 midgut development specific RNA
    polymerase II more
    85(a)     --


    ENSEMBL Gene Tree for HOXA7 (if available)
    TreeFam Gene Tree for HOXA7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HOXA7 gene
    HOXB52  HOXC62  HOXC52  HOXB42  HOXA52  ENSG000002732662  HOXA42  HOXC82  
    HOXA62  ENSG000002730492  HOXD82  HOXB62  HOXB82  HOXD42  HOXB72  HOXC42  
    14 SIMAP similar genes for HOXA7 using alignment to 2 protein entries:     HXA7_HUMAN (see all proteins):
    HOXA4    HOXB4    HOXB7    HOXB8    HOXC4    HOXC6
    HOXB5    HOXA5    HOXC5    HOXD9    HOXC8    HOXD8
    HOXA6    HOXD4

    Find genes that share paralogs with HOXA7           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for HOXA7
    PGOHUM00000262357


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HOXA7 (see all 42)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1931240131,2
    C--27196063(+) TGTGAG/TTTGGG 2 K N mis10--------
    rs23017201,2
    C,F,A,H--27196069(+) TTGGGC/AGCAAA 2 /A syn1 ese332Minor allele frequency- A:0.19EA NS NA WA CSA EU 7938
    rs23017211,2,,4
    C,F,A,H--27196113(+) AGAAGT/CCCCCG 2 /T /A mis1 ese329Minor allele frequency- C:0.29EA NS NA WA CSA EU 5710
    rs1457789681,2
    C,F--27196115(+) AAGCCC/GCCGCC 2 A G mis11Minor allele frequency- G:0.00NA 3348
    rs784103371,2
    C,F--27196116(+) AGCCCC/TCGCCG 2 R G mis12Minor allele frequency- T:0.01NA EU 4631
    rs1884295831,2
    --27196304(+) GACCGC/GCCACA 1 -- us2k10--------
    rs1116057071,2
    F--27196336(+) GCAGTT/CCTCAC 1 -- us2k11Minor allele frequency- C:0.00CSA 1
    rs1384380391,2
    --27196424(+) GCCCGA/CGCCCG 1 -- us2k10--------
    rs715395031,2
    C,F--27196434(+) GGCGGG/ACCTGG 1 -- us2k15Minor allele frequency- A:0.14NA EA 246
    rs1843388981,2
    --27196456(+) GAAAAA/TGACCT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for HOXA7 (27193335 - 27197555 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for HOXA7 (see all 12):    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv887856CNV Loss21882294
    nsv887876CNV Loss21882294
    nsv5674CNV Loss18451855
    dgv7233n71CNV Loss21882294
    dgv7231n71CNV Loss21882294
    nsv526526CNV Loss19592680
    dgv7236n71CNV Loss21882294
    dgv7234n71CNV Loss21882294
    dgv7232n71CNV Loss21882294
    nsv824042CNV Gain20364138

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 142950    OMIM disorders: --

    3 diseases for HOXA7:    
    About MalaCards
    acute leukemia    acute promyelocytic leukemia    esophageal squamous cell carcinoma


    Find genes that share disorders with HOXA7           About GenesLikeMe

    2 Novoseek inferred disease relationships for HOXA7 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    leukemia 26 1 11681416 (1)
    acute leukemia 24.8 1 15160920 (1)

    Genetic Association Database (GAD): HOXA7
    Human Genome Epidemiology (HuGE) Navigator: HOXA7 (10 documents)

    Export disorders for HOXA7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HOXA7 gene, integrated from 10 sources (see all 71):
    (articles sorted by number of sources associating them with HOXA7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human homeobox HOXA7 regulates keratinocyte transglutaminase type 1 and inhibits differentiation. (PubMed id 11435435)1, 2, 9 La Celle P.T. and Polakowska R.R. (J. Biol. Chem. 2001)
    2. Sequence analysis and tissue specific expression of human HOXA7. (PubMed id 10911612)1, 2, 9 Kim M.H.... Park H.W. (Mol. Biotechnol. 2000)
    3. Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. (PubMed id 20634891)1, 4 Jugessur A....Murray J.C. (PLoS ONE 2010)
    4. High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. (PubMed id 19453261)1, 4 Yerges L.M....Zmuda J.M. (J. Bone Miner. Res. 2009)
    5. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (Science 2003)
    6. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (Nature 2003)
    7. Sequence characterisation and expression of homeobox HOX A7 in the multi-potential erythroleukaemic cell line TF-1. (PubMed id 9804983)1, 2 McIlhatton M.A.... Lappin T.R. (Biochim. Biophys. Acta 1998)
    8. Vertebrate homeobox gene nomenclature. (PubMed id 1358459)1, 3 Scott M.P. (Cell 1992)
    9. Nomenclature for human homeobox genes. (PubMed id 1973146)1, 3 McAlpine P.J. and Shows T.B. (Genomics 1990)
    10. Organization of human class I homeobox genes. (PubMed id 2576652)1, 2 Boncinelli E.... Simeone A. (Genome 1989)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 3204 HGNC: 5108 AceView: HOXA7.1 Ensembl:ENSG00000122592 euGenes: HUgn3204
    ECgene: HOXA7 H-InvDB: HOXA7

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HOXA7 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for HOXA7 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for HOXA7 gene:
    Search GeneIP for patents involving HOXA7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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