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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HOXA7 Gene

protein-coding   GIFtS: 53
GCID: GC07M027193

homeobox A7

(Previous name: homeo box A7 )
(Previous symbols: HOX1A, HOX1)
 Explore 17 diseases affiliated with
HOXA7 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for HOXA7    

Aliases
for HOXA7 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Homeobox A71 2     Homeobox Protein Hox-1A2 3
HOX1A1 2 3 5     ANTP2
HOX11 2     HOX1.12
Homeo Box A71 2     Homeobox Protein Hox-A72
Homeobox Protein Hox 1.12 3     

External Ids:    HGNC: 51081   Entrez Gene: 32042   Ensembl: ENSG000001225927   OMIM: 1429505   UniProtKB: P312683   

Export aliases for HOXA7 gene to outside databases

Previous GC identifers: GC07M026836 GC07M026936 GC07M026967 GC07M027159


Summaries
for HOXA7 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for HOXA7:
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named
A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during
embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription
factor which may regulate gene expression, morphogenesis, and differentiation. For example, the encoded protein
represses the transcription of differentiation-specific genes during keratinocyte proliferation, but this repression
is then overcome by differentiation signals. This gene is highly similar to the antennapedia (Antp) gene of
Drosophila. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: HXA7_HUMAN, P31268
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells
with specific positional identities on the anterior-posterior axis

Gene Wiki entry for HOXA7


Genomic Views
for HOXA7 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.1  NT_007819.17  NT_079592.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HOXA7 gene promoter:
         CREB   Sp1   p53   deltaCREB   c-Myb   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): HOXA7 promoter sequence
   Search SABiosciences Chromatin IP Primers for HOXA7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HOXA7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p15.2   Ensembl cytogenetic band:  7p15.2   HGNC cytogenetic band: 7p15.2

HOXA7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HOXA7 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M027193:  view genomic region     (about GC identifiers)

Start:
 27,193,335 bp from pter      End:
 27,197,555 bp from pter
Size:
 4,221 bases      Orientation:
 minus strand

1 alternative location:
Chr7-,CRA_TCAG 27,244,510-27,247,471     

Proteins
for HOXA7 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: HXA7_HUMAN, P31268 (See protein sequence)
Recommended Name: Homeobox protein Hox-A7  
Size: 230 amino acids; 25355 Da
Subcellular location: Nucleus
Secondary accessions: A4D191 O43368 O43486 O95655 Q9NSC8 Q9UDM1

Explore the universe of human proteins at neXtProt for HOXA7: NX_P31268

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P31268

    • HOXA7 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_008827.2  
    ENSEMBL proteins: 
     ENSP00000242159   ENSP00000428563  

    Human Recombinant Protein Products: 
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    Novus Biologicals HOXA7 Proteins
    Novus Biologicals HOXA7 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for HOXA7

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IC11435435


    HOXA7 for ontologies           About GeneDecksing



    HOXA7 Antibody Products: 
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    Uscn Antibodies for HOXA7
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    Uscn ELISAs and CLIAs for HOXA7

    Protein Domains /
    Families
    for HOXA7 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HOXA7 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR001827 Homeobox_Antennapedia_CS
     IPR020479 Homeobox_metazoa
     IPR017995 Homeobox_antennapedia
     IPR017970 Homeobox_CS
     IPR001356 Homeodomain

    Graphical View of Domain Structure for InterPro Entry P31268

    ProtoNet protein and cluster: P31268

    1 Blocks protein family: IPB001827 Homeobox protein

    UniProtKB/Swiss-Prot: HXA7_HUMAN, P31268
    Similarity: Belongs to the Antp homeobox family
    Similarity: Contains 1 homeobox DNA-binding domain


    Function
    for HOXA7 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: HXA7_HUMAN, P31268
    Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells
    with specific positional identities on the anterior-posterior axis

         Genatlas biochemistry entry for HOXA7:
    homeo box A7(1A),homologous to mouse Hox-1.1,Drosophila Antp,Ubx,abd-A,expressed in erythroleukemic cell line

    miRNA
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    hsa-mir-196a (MIRT002940)

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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HOXA7
    8/27 QIAGEN miScript miRNA Assays for microRNAs that regulate HOXA7 (see all 27):
    hsa-miR-607 hsa-miR-3673 hsa-miR-185* hsa-miR-520d-5p hsa-miR-548v hsa-miR-221 hsa-miR-144 hsa-miR-199b-5p
    SwitchGear 3'UTR luciferase reporter plasmid: HOXA7 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HOXA7 (see all 4)
    OriGene shRNA RFP: HOXA7
    OriGene siRNA: HOXA7
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    Gene Editing
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    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HOXA7 (see all 2)
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    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HOXA7 

    Cell Line
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    Search LifeMap BioReagents cell lines for HOXA7

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HOXA7

    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0008134transcription factor binding IPI18973687
    GO:0043565sequence-specific DNA binding IDA11435435


    HOXA7 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out Hoxa7tm1Mrc for HOXA7
         4 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Hoxa7):
     hematopoietic system  immune system  normal  skeleton 

    HOXA7 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for HOXA7 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for HOXA7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    5/10 Interacting proteins for HOXA7 (P312683 ENSP000002421594) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MEIS1O004703, ENSP000002723694I2D: score=1 STRING: ENSP00000272369
    GMNNO754963, ENSP000002300564I2D: score=4 STRING: ENSP00000230056
    KAT6AQ927943, ENSP000002657134I2D: score=1 STRING: ENSP00000265713
    MEN1O002553, ENSP000003370884I2D: score=1 STRING: ENSP00000337088
    PSIP1O754753, ENSP000003701094I2D: score=1 STRING: ENSP00000370109
    About this table

    Gene Ontology (GO): 5/12 biological process terms (GO ID links to tree view) (see all 12):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IDA11435435
    GO:0001525angiogenesis IEP17972163
    GO:0001953negative regulation of cell-matrix adhesion IDA14704364
    GO:0002686negative regulation of leukocyte migration IDA14704364
    GO:0006351transcription, DNA-dependent IEA--


    HOXA7 for ontologies           About GeneDecksing



    Drugs & Compounds
    for HOXA7 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HOXA7
    Search CenterWatch for drugs/clinical trials and news about HOXA7 / HXA7 

    Transcripts
    for HOXA7 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for HOXA7 gene: 
    NM_006896.3  

    Unigene Clusters for HOXA7:

    Homeobox A7
    Hs.610216  [show with all ESTs], Hs.660918  [show with all ESTs]
    Unigene Representative Sequences: NR_038831, AF026397
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000242159(uc003sys.3) ENST00000523796 ENST00000519842

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HOXA7
    8/27 QIAGEN miScript miRNA Assays for microRNAs that regulate HOXA7 (see all 27):
    hsa-miR-607 hsa-miR-3673 hsa-miR-185* hsa-miR-520d-5p hsa-miR-548v hsa-miR-221 hsa-miR-144 hsa-miR-199b-5p
    SwitchGear 3'UTR luciferase reporter plasmid: HOXA7 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HOXA7 (see all 4)
    OriGene shRNA RFP: HOXA7
    OriGene siRNA: HOXA7
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HOXA7
    Clone
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    GenScript: all cDNA clones in your preferred vector: HOXA7 (NM_006896)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HOXA7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HOXA7 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HOXA7
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat HOXA7
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HOXA7
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HOXA7

    Additional cDNA sequence: 

    AF026397.1 BC061916.1 

    6 DOTS entries:

    DT.75101351  DT.121115444  DT.40253843  DT.99932800  DT.70100491  DT.40285593 

    24/34 AceView cDNA sequences (see all 34):

    AK096334 AW450250 AW450368 BE645526 AW470294 AI650267 AI887912 AK091933 
    AA557521 AW205417 AX747263 BF970710 AI492051 AI660992 BF510786 AK092154 
    AI762011 AI830321 AA570160 BE146237 BE146039 H28870 AW292631 F37656 

    GeneLoc Exon Structure


    Expression
    for HOXA7 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HOXA7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AAGTGGAAGA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    HOXA7 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 3 LifeMap Cells 
    NameCategory
    mK4 (Cell line)Kidney
    mK3 (Cell line)Kidney
    CD31, CD144 positive cells (Two-step protocol fo...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See HOXA7 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HOXA7

    SOURCE GeneReport for Unigene clusters: Hs.610216 Hs.660918
        SABiosciences Expression via Pathway-Focused PCR Arrays including HOXA7: 
              Stem Cell Transcription Factors in human mouse rat
              Homeobox (HOX) Genes in human mouse rat

    Primer
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HOXA7

    Orthologs
    for HOXA7 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for HOXA7 gene from 5/20 species (see all 20)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves HOXA76
    		 homeobox A7
    		 75(a)
    		 1 ↔ 1
    		 2(32570286-32571988)
    lizard
    (Anolis carolinensis)    		 Reptilia HOXA76
    		 --
    		 63(a)
    		 1 ↔ 1
    		 GL343275.1(1454822-1457870)
    African clawed frog
    (Xenopus laevis)    		 Amphibia hox362 homeobox protein 77.93(n)    M24752.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Antp3 midgut development specific RNA polymerase
    II more    		 85(a)     --
    worm
    (Caenorhabditis elegans)    		 Secernentea lin-396
    		 Homeobox protein lin-39
    		 20(a)
    		 possible ortholog
    		 III(7528603-7536567)


    ENSEMBL Gene Tree for HOXA7 (if available)
    TreeFam Gene Tree for HOXA7 (if available) 

    Paralogs
    for HOXA7 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HOXA7 gene
    GSX12  HOXA12  HOXD12  HOXA22  HOXB32  HOXC62  HOXB52  GSX22  
    HOXC52  HOXB42  HOXA52  HOXA42  HOXD32  HOXC82  HOXA62  HOXA32  
    HOXD82  HOXB12  HOXB62  HOXB82  HOXD42  HOXB22  HOXB72  PDX12  
    HOXC42  
    14 SIMAP similar genes for HOXA7 using alignment to 2 protein entries:     HXA7_HUMAN (see all proteins):
    HOXA4    HOXB4    HOXB7    HOXB8    HOXC4    HOXC6
    HOXB5    HOXA5    HOXC5    HOXD9    HOXC8    HOXD8
    HOXA6    HOXD4

    HOXA7 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for HOXA7
    PGOHUM00000262357


    Genomic Variants
    for HOXA7 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/96 NCBI SNPs in HOXA7 are shown (see all 96)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 7 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1856522021,2
    		--27193249(+) AGCCAC/GCCCAC 3 -- nc-transcript-variantds50010--------
    rs753004731,2
    		C,--27193281(+) TGCCCC/TCCAGC 3 -- nc-transcript-variantds50010--------
    rs1168954841,2
    		--27193316(+) CCCCTC/GTGGAT 3 -- nc-transcript-variantds50011Minor allele frequency- G:0.01NA 120
    rs1907501551,2
    		--27193413(+) GAACCC/GCAGGA 3 -- nc-transcript-variantut310--------
    rs175009181,2
    		C,H--27193478(+) ATTGGA/GCCTCC 3 -- nc-transcript-variantut311Minor allele frequency- G:0.00NS 114
    rs1815910171,2
    		--27193575(+) ACAAAC/TGAACT 3 -- nc-transcript-variantut310--------
    rs175009251,2
    		C,F,H,--27193600(+) ATGATA/TAAAAA 3 -- nc-transcript-variantut315Minor allele frequency- T:0.03NS EA WA 514
    rs10575121,2
    		C,F,H--27193603(-) TTTTTT/ATTTAT 3 -- ut31 nc-transcript-variant7Minor allele frequency- A:0.00MN NS EA NA 762
    rs1876496771,2
    		--27193646(+) GGAAAC/TATCAG 3 -- nc-transcript-variantut310--------
    rs1510120221,2
    		--27193655(+) AGGGCA/GTACAT 3 -- nc-transcript-variantut310--------

    HapMap Linkage Disequilibrium report for HOXA7 (27193335 - 27197555 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for HOXA7: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HOXA7
    DNA2.0 Custom Variant and Variant Library Synthesis for HOXA7

    Disorders / Diseases
    for HOXA7 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    HOXA7 for disorders           About GeneDecksing

    OMIM gene information: 142950    OMIM disorders: --

    17 diseases for HOXA7:    About MalaCards
    craniofacial abnormalities    squamous cell carcinoma    oral squamous cell carcinoma    esophageal squamous cell carcinoma
    acute promyelocytic leukemia    epithelial ovarian cancer    acute leukemia    teratoma
    ovarian cancer    teratocarcinoma    leukemia    cervical cancer
    esophagitis    cervicitis    lung cancer    carcinoma
    neuronitis

    2 Novoseek disease relationships for HOXA7 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    leukemia 26 1 11681416 (1)
    acute leukemia 24.8 1 15160920 (1)

    Human Genome Epidemiology (HuGE) Navigator: HOXA7 (10 documents)

    Export disorders for HOXA7 gene to outside databases

    Publications
    for HOXA7 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HOXA7 gene, integrated from 9 sources (see all 68):
    (articles sorted by number of sources associating them with HOXA7)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Human homeobox HOXA7 regulates keratinocyte transglutaminase type 1 and inhibits differentiation. (PubMed id 11435435)1, 2, 9 La Celle P.T. and Polakowska R.R. (2001)
    2. Sequence analysis and tissue specific expression of human HOXA7. (PubMed id 10911612)1, 2, 9 Kim M.H.... Park H.W. (2000)
    3. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
    4. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
    5. Sequence characterisation and expression of homeobox HOX A7 in the multi-potential erythroleukaemic cell line TF-1. (PubMed id 9804983)1, 2 McIlhatton M.A.... Lappin T.R. (1998)
    6. Vertebrate homeobox gene nomenclature. (PubMed id 1358459)1, 3 Scott M.P. (1992)
    7. Nomenclature for human homeobox genes. (PubMed id 1973146)1, 3 McAlpine P.J. and Shows T.B. (1990)
    8. Organization of human class I homeobox genes. (PubMed id 2576652)1, 2 Boncinelli E.... Simeone A. (1989)
    9. HOX gene analysis of endothelial cell differentiation in human bone marrow-derived mesenchymal stem cells. (PubMed id 17972163)1, 9 Chung N....Rha H.K. (2009)
    10. HOX cofactors expression and regulation in the human ovary. (PubMed id 18973687)1, 9 Ota T....Leung P.C. (2008)

    External Searches for HOXA7 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Genome Databases showing HOXA7 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 3204 HGNC: 5108 AceView: HOXA7.1 Ensembl:ENSG00000122592 euGenes: HUgn3204
    ECgene: HOXA7 H-InvDB: HOXA7

    Other Databases showing HOXA7 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing HOXA7 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HOXA7 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for HOXA7 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for HOXA7 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for HOXA7 gene:
    Search GeneIP for patents involving HOXA7

    GeneCards and IP:
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