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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HOXA2 Gene

protein-coding   GIFtS: 53
GCID: GC07M027106

homeobox A2

(Previous name: homeo box A2 )
(Previous symbol: HOX1K)
 Explore 8 diseases affiliated with
HOXA2 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for HOXA2    

Aliases
for HOXA2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Homeobox A21 2
HOX1K1 2 3
Homeobox Protein Hox-1K2 3
Homeo Box A21
Homeobox Protein Hox-A22

External Ids:    HGNC: 51031   Entrez Gene: 31992   Ensembl: ENSG000001059967   OMIM: 6046855   UniProtKB: O433643   

Export aliases for HOXA2 gene to outside databases

Previous GC identifers: GC07M026782 GC07M026881 GC07M026882 GC07M026913 GC07M027020


Summaries
for HOXA2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for HOXA2:
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named
A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during
embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription
factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in
the placement of hindbrain segments in the proper location along the anterior-posterior axis during development.
(provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: HXA2_HUMAN, O43364
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells
with specific positional identities on the anterior-posterior axis

Gene Wiki entry for HOXA2


Genomic Views
for HOXA2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.1  NT_007819.17  NT_079592.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HOXA2 gene promoter:
         Nkx2-5   HNF-4alpha2   C/EBPalpha   GATA-2   HNF-4alpha1   AREB6   SRY   HSF2   Sox9   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: HOXA2 promoter sequence
   Search SABiosciences Chromatin IP Primers for HOXA2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HOXA2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p15.2   Ensembl cytogenetic band:  7p15.2   HGNC cytogenetic band: 7p15.2

HOXA2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HOXA2 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M027106:  view genomic region     (about GC identifiers)

Start:
 27,139,721 bp from pter      End:
 27,142,430 bp from pter
Size:
 2,710 bases      Orientation:
 minus strand

1 alternative location:
Chr7-,CRA_TCAG 27,191,126-27,193,547     

Proteins
for HOXA2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: HXA2_HUMAN, O43364 (See protein sequence)
Recommended Name: Homeobox protein Hox-A2  
Size: 376 amino acids; 41002 Da
Subcellular location: Nucleus
Secondary accessions: A1L4K3 B2RMW3

Explore the universe of human proteins at neXtProt for HOXA2: NX_O43364

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O43364

    • HOXA2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_006726.1  
    ENSEMBL proteins: 
     ENSP00000222718  

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    Uscn Proteins for HOXA2

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--


    HOXA2 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for HOXA2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HOXA2 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR001827 Homeobox_Antennapedia_CS
     IPR020479 Homeobox_metazoa
     IPR017970 Homeobox_CS
     IPR001356 Homeodomain
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry O43364

    ProtoNet protein and cluster: O43364

    2 Blocks protein families:
    IPB000047 Lambda and other repressor helix-turn-helix signature
    IPB001827 Homeobox protein


    UniProtKB/Swiss-Prot: HXA2_HUMAN, O43364
    Similarity: Belongs to the Antp homeobox family. Proboscipedia subfamily
    Similarity: Contains 1 homeobox DNA-binding domain


    Function
    for HOXA2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: HXA2_HUMAN, O43364
    Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells
    with specific positional identities on the anterior-posterior axis

         Genatlas biochemistry entry for HOXA2:
    homeo box A2(1K),homologous to mouse Hox-1.11,Drosophila pb

    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate HOXA2:
    hsa-miR-33a*
    SwitchGear 3'UTR luciferase reporter plasmid: HOXA2 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0043565sequence-specific DNA binding IEA--


    HOXA2 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for HOXA2:
     Decreased viability 

    Animal Models:
         Mouse knock-outs for HOXA2: Hoxa2tm1Ipc Hoxa2tm1.2Fmr Hoxa2tm1Grid Hoxa2tm2Fmr Hoxa2tm1Mrc
         14 MGI mutant phenotypes (inferred from 10 alleles) (MGI details for Hoxa2):
     behavior/neurological  cardiovascular system  cellular  craniofacial  digestive/alimentary 
     embryogenesis  growth/size  hearing/vestibular/ear  mortality/aging  muscle 
     nervous system  normal  respiratory system  skeleton 

    HOXA2 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for HOXA2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HOXA2

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    5/15 Interacting proteins for HOXA2 (O433643 ENSP000002227184) via UniProtKB, MINT, STRING, and/or I2D (see all 15)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MEIS1O004703, ENSP000002723694I2D: score=3 STRING: ENSP00000272369
    ASB12Q8WXK43I2D: score=1 
    BRCA1P383983I2D: score=1 
    CERS2Q96G233I2D: score=1 
    CHD4Q148393I2D: score=1 
    About this table

    Gene Ontology (GO): 5/19 biological process terms (GO ID links to tree view) (see all 19):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IEA--
    GO:0001709cell fate determination IEA--
    GO:0002076osteoblast development IEA--
    GO:0006351transcription, DNA-dependent IEA--
    GO:0007379segment specification IEA--


    HOXA2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for HOXA2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HOXA2
    Search CenterWatch for drugs/clinical trials and news about HOXA2 / HXA2 

    Transcripts
    for HOXA2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for HOXA2 gene: 
    NM_006735.3  

    Unigene Cluster for HOXA2:

    Homeobox A2
    Hs.592177  [show with all ESTs]
    Unigene Representative Sequence: NM_006735
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000222718(uc003syh.3)

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    hsa-miR-33a*
    SwitchGear 3'UTR luciferase reporter plasmid: HOXA2 3' UTR sequence
    Inhib. RNA
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    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HOXA2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HOXA2

    Additional cDNA sequence: 

    AK291164.1 AL079274.1 BC130571.1 BC136500.1 

    2 DOTS entries:

    DT.207842  DT.75161512 

    24/27 AceView cDNA sequences (see all 27):

    BF940394 BI010103 AI581335 NM_006735 BF509655 BE465040 AI174765 AW579346 
    AW385940 W72556 AI796505 AA627201 AI140882 AW299721 AK096742 BE265850 
    AL079274 AI692874 AW579357 AW292406 AW385936 BF089689 AW079894 W76504 

    GeneLoc Exon Structure


    Expression
    for HOXA2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HOXA2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CATATTTTTT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    HOXA2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    10/27 LifeMap In Vivo Development Anatomical Compartments/Cells (see all 27) 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Head MesenchymeBranchial Arch 2Cranial Neural Crest CellsNeural Crest
    Head MesenchymeBranchial Arch 2Osteochondro Mesenchymal CellsBone, Cartilage
    BoneAutopod PeriosteumImmature Endochondral OsteoblastsBone
    BoneCaudal Endochondral BonesEndochondral OsteoblastsBone
    BoneCaudal Endochondral BonesEndochondral PreosteoblastsBone
    BoneCervical VertebraeImmature Endochondral OsteoblastsBone
    BoneEndochondral Facial BonesEndochondral OsteoblastsBone
    BoneEndochondral Facial BonesEndochondral PreosteoblastsBone
    BoneLumbar VertebraeImmature Endochondral OsteoblastsBone
    BoneMembranous Facial BonesIntramembranous OsteoblastsBone
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 10/11 LifeMap Cells (see all 11) 
    NameCategory
    PureStem™ myogenic progenitor Z11 (Embryonic Progenitor Cell)Heart, Myocardium, Smooth Muscle
    PureStem™ mesenchymal progenitor E15 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    PureStem™ progenitor EN13 (Embryonic Progenitor Cell)
    PureStem™ progenitor EN2 (Embryonic Progenitor Cell)
    PureStem™ progenitor EN7 (Embryonic Progenitor Cell)
    PureStem™ progenitor RASMO12 (Embryonic Progenitor Cell)
    PureStem™ progenitor SM22 (Embryonic Progenitor Cell)
    PureStem™ progenitor U31 (Embryonic Progenitor Cell)
    PureStem™ progenitor W10 (Embryonic Progenitor Cell)
    Primordial-like germ cells (cKIT+ SSEA1+ VASA+) (Derivation of primor...)

    See HOXA2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HOXA2

    SOURCE GeneReport for Unigene cluster: Hs.592177
        SABiosciences Expression via Pathway-Focused PCR Arrays including HOXA2: 
              Stem Cell Transcription Factors in human mouse rat
              Homeobox (HOX) Genes in human mouse rat

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    In Situ
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    Orthologs
    for HOXA2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for HOXA2 gene from 5/16 species (see all 16)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves HOXA21 homeobox A2 86.51(n)
    87.4(a)    		   396055  NM_205150.1  NP_990481.1 
    lizard
    (Anolis carolinensis)    		 Reptilia HOXA26
    		 --
    		 82(a)
    		 1 ↔ 1
    		 GL343275.1(1530375-1532456)
    African clawed frog
    (Xenopus laevis)    		 Amphibia hoxa2b-A2 transcription factor Hoxa2b 84.06(n)    AF307009.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii hoxa2b2 homeo box A2b 79.28(n)   30325  AF307010.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta pb6
    		 proboscipedia
    		 12(a)
    		 1 ↔ 1
    		 3R(2533518-2567785)


    ENSEMBL Gene Tree for HOXA2 (if available)
    TreeFam Gene Tree for HOXA2 (if available) 

    Paralogs
    for HOXA2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HOXA2 gene
    GSX12  HOXA72  HOXA12  HOXD12  HOXB32  HOXC62  HOXB52  GSX22  
    HOXC52  HOXB42  HOXA52  HOXA42  HOXD32  HOXC82  HOXA62  HOXA32  
    HOXD82  HOXB12  HOXB62  HOXB82  HOXD42  HOXB22  HOXB72  PDX12  
    HOXC42  
    1 SIMAP similar gene for HOXA2 using alignment to 1 protein entry:     HXA2_HUMAN:
    HOXB2

    HOXA2 for paralogs           About GeneDecksing



    Genomic Variants
    for HOXA2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/91 NCBI SNPs in HOXA2 are shown (see all 91)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 7 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1511713391,2
    		--27139519(+) CAAATG/TAATTG 3 -- nc-transcript-variantds50010--------
    rs755375621,2
    		--27139576(+) ACTCCA/GTGTTA 3 -- nc-transcript-variantds50010--------
    rs1502956551,2
    		--27139582(+) TGTTAC/TTCATT 3 -- nc-transcript-variantds50010--------
    rs154941,2
    		C,F,H,--27139700(-) TTCAAG/TCCATA 3 -- nc-transcript-variantds500113Minor allele frequency- T:0.11MN NS EA NA CSA WA 1498
    rs7060171,2
    		C,F,A,H,--27139878(+) AAAGAA/GGATAA 1 -- ds500124Minor allele frequency- G:0.07NS EA NA WA CSA 2270
    rs1464348751,2
    		--27139890(+) TTGTGA/CCGAAT 3 -- int1 ds50010--------
    rs1414146001,2
    		--27140029(+) TCCCAA/GTGTAA 3 -- int1 ut310--------
    rs1451792871,2
    		--27140035(+) TGTAAC/TACAAA 3 -- ut31 int10--------
    rs174275531,2
    		H--27140044(+) AAAATA/TAAAAG 3 -- int1 ut31 trp34Minor allele frequency- T:0.00NS EA 414
    rs1176304211,2
    		C,F,--27140237(+) GGGAAG/AGGGTA 3 -- int1 ut311Minor allele frequency- A:0.04NA 120

    HapMap Linkage Disequilibrium report for HOXA2 (27139721 - 27142430 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for HOXA2: --
    Human Gene Mutation Database (HGMD): HOXA2

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HOXA2
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    Disorders / Diseases
    for HOXA2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    HOXA2 for disorders           About GeneDecksing

    OMIM gene information: 604685   
    OMIM disorders: 612290  
    UniProtKB/Swiss-Prot: HXA2_HUMAN, O43364
  • Defects in HOXA2 are a cause of microtia hearing impairment and cleft palate (MHICP) [MIM:612290]. Microtia is
    • a congenital deformity of the outer ear and occurs in approximately one in 8'000-10'000 births. It is characterized by
    a small, abnormally shaped outer ear. It can be unilateral or bilateral. Syndromic forms of microtia occur in
    conjunction with other abnormalities. The most common associated malformations is the cleft palate, a congenital
    fissure of the soft and/or hard palate due to faulty fusion. Defects in HOXA2 are a cause of autosomal-recessive
    bilateral microtia, mixed symmetrical severe to profound hearing impairment and partial cleft palate

    8 diseases for HOXA2:    About MalaCards
    microtia, hearing impairment, and cleft palate    bamforth-lazarus syndrome    cleft palate    microtia
    choanal atresia    treacher collins syndrome    clubfoot    neuronitis

    2 diseases from the University of Copenhagen DISEASES database for HOXA2:
    Bamforth-Lazarus syndrome     Cleft palate
    Human Genome Epidemiology (HuGE) Navigator: HOXA2 (3 documents)

    Export disorders for HOXA2 gene to outside databases

    Publications
    for HOXA2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HOXA2 gene, integrated from 9 sources (see all 29):
    (articles sorted by number of sources associating them with HOXA2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. A mutation in HOXA2 is responsible for autosomal-recessive microtia in an Iranian family. (PubMed id 18394579)1, 2 Alasti F....Van Camp G. (2008)
    2. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
    3. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
    4. Vertebrate homeobox gene nomenclature. (PubMed id 1358459)1, 3 Scott M.P. (1992)
    5. Mutational analysis of HOXA2 and SIX2 in a Bronx popu lation with isolated microtia. (PubMed id 20542577)1 Monks D.C....Babcock M. (2010)
    6. Altered transmission of HOX and apoptotic SNPs identi fy a potential common pathway for clubfoot. (PubMed id 19938081)1 Ester A.R....Hecht J.T. (2009)
    7. High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. (PubMed id 19453261)1 Yerges L.M....Zmuda J.M. (2009)
    8. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    9. Range of HOX/TALE superclass associations and protein domain requirements for HOXA13:MEIS interaction. (PubMed id 15617687)1 Williams T.M....Innis J.W. (2005)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)

    External Searches for HOXA2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing HOXA2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 3199 HGNC: 5103 AceView: HOXA2 Ensembl:ENSG00000105996 euGenes: HUgn3199
    ECgene: HOXA2 H-InvDB: HOXA2

    Other Databases showing HOXA2 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing HOXA2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HOXA2 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for HOXA2 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for HOXA2 gene:
    Search GeneIP for patents involving HOXA2

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