Aliases for HOXA2 Gene
External Ids for HOXA2 Gene
Previous HGNC Symbols for HOXA2 Gene
Previous GeneCards Identifiers for HOXA2 Gene
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development. [provided by RefSeq, Jul 2008]
GeneCards Summary for HOXA2 Gene
HOXA2 (Homeobox A2) is a Protein Coding gene. Diseases associated with HOXA2 include microtia, hearing impairment, and cleft palate and microtia. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Developmental Biology. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and sequence-specific DNA binding. An important paralog of this gene is HOXD3.
UniProtKB/Swiss-Prot for HOXA2 Gene
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.