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HOXA distal transcript antisense RNA(Previous names: non-protein coding RNA 213, HOXA distal transcript antisense...) (Previous symbol: NCRNA00213)
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Aliases for HOTTIP gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
| Subcategory (RNA class): antisense
Quality score for this RNA gene is 3
| Aliases |
|---|
| HOXA Distal Transcript Antisense RNA1 2 | | RP1-170O19.31 | | HOXA-AS61 2 | | HOXA Distal Transcript Antisense RNA (Non-Protein Coding)1 | | HOXA13-AS11 2 | | Non-Protein Coding RNA 2131 | | NCRNA002131 2 | | |
Export aliases for HOTTIP gene to outside databasesPrevious GC identifer: GC07P027246 |
Summaries for HOTTIP gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| -- |
Genomic Views for HOTTIP gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007819.17 NT_079592.2
Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for HOTTIP Other transcription factors
Search SABiosciences Chromatin IP Primers for HOTTIP
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HOTTIP |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7p15.2 Ensembl cytogenetic band: 7p15.2 HGNC cytogenetic band: 7p15.2HOTTIP Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P027249: view genomic region
(about GC identifiers)
Start:
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27,238,194 bp from pter |
End:
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27,246,878 bp from pter |
Size:
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8,685 bases |
Orientation:
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plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 27,291,241-27,293,634 |
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Proteins for HOTTIP gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB: --
|
Protein
Domains / Families for HOTTIP gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| -- |
Function for HOTTIP gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Animal Models:
Cell Line Products: |  | GenScript Custom overexpressing Cell Line Services for HOTTIP | |  | Search LifeMap BioReagents cell lines for HOTTIP | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HOTTIP |
Pathways & Interactions for HOTTIP gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HOTTIP
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Drugs & Compounds for HOTTIP gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
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Browse Tocris compounds for HOTTIP Search CenterWatch for drugs/clinical trials and news about HOTTIP 
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Transcripts for HOTTIP gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| Unigene Cluster for HOTTIP: HOXA distal transcript antisense RNA Hs.199486 [show with all ESTs]Unigene Representative Sequence: NR_0378433 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000421733 ENST00000521028(uc022aau.1) ENST00000472494
Additional cDNA sequence: AK093987.1 GU724873.1 NR_037843.2 2 DOTS entries: DT.40291523 DT.70103504 GeneLoc Exon Structure
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Expression for HOTTIP gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| Expression evidence for HOTTIP:none
HOTTIP expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: GCGCAGCTGC
 About this image Genevestigator expression for HOTTIP
SOURCE GeneReport for Unigene cluster: Hs.199486 SABiosciences Custom PCR Arrays for HOTTIP
Primer Products: |  | Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene validated miRNA SYBR primer pairs
| |  | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat HOTTIP | |  | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HOTTIP | |  | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HOTTIP | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HOTTIP |
Orthologs for HOTTIP gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for HOTTIP (if available) TreeFam Gene Tree for HOTTIP (if available)  |
Paralogs for HOTTIP gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
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Genomic Variants for HOTTIP gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 7 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
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HapMap Linkage Disequilibrium report for HOTTIP (27238194 - 27246878 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for HOTTIP: --  | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases for HOTTIP gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
HOTTIP for disorders About MalaCards
HOTTIP for disorders About GeneDecksing
OMIM gene information: 614060
OMIM disorders: --
Export disorders for HOTTIP gene to outside databases
|
Publications for HOTTIP gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for HOTTIP gene integrated from 9 sources: (articles sorted by number of sources associating them with HOTTIP) | |  | Utopia: connect your pdf to the dynamic world of online information |
- A long noncoding RNA maintains active chromatin to co ordinate homeotic gene expression. (PubMed id 21423168)1, 3 Wang K.C....Chang H.Y. (2011)
- Non-coding RNA: HOTTIP goes the distance. (PubMed id 21483457)1, 3 Burgess D.J. (2011)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
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External Searches for HOTTIP gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
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Genome Databases showing HOTTIP gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing HOTTIP gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing HOTTIP gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for HOTTIP | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for HOTTIP gene: Search GeneIP for patents involving HOTTIP
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for HOTTIP gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HOTTIP | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HOTTIP | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HOTTIP | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HOTTIP | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HOTTIP | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HOTTIP |
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 |  |  |  | |
| | | Search Tocris compounds for HOTTIP |
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 | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HOTTIP |
|  |  |  |  | | | Search ThermoFisher Antibodies for HOTTIP |
| | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat HOTTIP |
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Last full update: 19 Mar 2013 -
Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 14 May 2013
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