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HORMAD1 Gene

protein-coding   GIFtS: 50
GCID: GC01M150670

HORMA Domain Containing 1

  Search for HORMAD1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
HORMA Domain Containing 11 2
Cancer/Testis Antigen 461 2 3
NOHMA2 3 5
Newborn Ovary HORMA Protein2 3
CT462 3
HORMA Domain-Containing Protein 12

External Ids:    HGNC: 252451   Entrez Gene: 840722   Ensembl: ENSG000001434527   OMIM: 6098245   UniProtKB: Q86X243   

Export aliases for HORMAD1 gene to outside databases

Previous GC identifers: GC01M147484 GC01M148937 GC01M122049


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for HORMAD1 Gene:
This gene encodes a HORMA domain-containing protein. HORMA domains are involved in chromatin binding and play a
role in cell cycle regulation. The encoded protein may play a role in meiosis, and expression of this gene is a
potential marker for cancer. A pseudogene of this gene is located on the long arm of chromosome 6. Alternatively
spliced transcript variants encoding multiple isoforms have been observed for this gene. (provided by RefSeq, Dec
2010)

GeneCards Summary for HORMAD1 Gene:
HORMAD1 (HORMA domain containing 1) is a protein-coding gene. An important paralog of this gene is HORMAD2.

UniProtKB/Swiss-Prot: HORM1_HUMAN, Q86X24
Function: Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that
sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by
increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation
independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the
female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome
regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic
prophase quality control in both sexes (By similarity)

Gene Wiki entry for HORMAD1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_004487.20  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the HORMAD1 gene promoter:
         Nkx3-1   Nkx3-1 v4   Nkx3-1 v1   HNF-1A   Gfi-1   Nkx3-1 v2   HNF-1   FOXJ2 (long isoform)   Nkx3-1 v3   FOXJ2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHORMAD1 promoter sequence
   Search Chromatin IP Primers for HORMAD1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HORMAD1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21.3   Ensembl cytogenetic band:  1q21.3   HGNC cytogenetic band: 1q21.2

HORMAD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HORMAD1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M150670:  view genomic region     (about GC identifiers)

Start:
150,670,535 bp from pter      End:
150,693,364 bp from pter
Size:
22,830 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: HORM1_HUMAN, Q86X24 (See protein sequence)
Recommended Name: HORMA domain-containing protein 1  
Size: 394 amino acids; 45200 Da
Subunit: Interacts with HORMAD2 (By similarity)
Sequence caution: Sequence=AAH33014.1; Type=Frameshift; Positions=89;
Secondary accessions: A6NMK2 B3KUK1 Q4G114 Q5T5I3 Q5T5I4 Q5T5I5 Q6FIC1 Q9H0K8
Alternative splicing: 5 isoforms:  Q86X24-1   Q86X24-2   Q86X24-3   Q86X24-4   Q86X24-5   

Explore the universe of human proteins at neXtProt for HORMAD1: NX_Q86X24

Explore proteomics data for HORMAD1 at MOPED

Post-translational modifications: 

  • Phosphorylated at Ser-377 in a SPO11-dependent manner (By similarity)1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See HORMAD1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001186758.1  NP_115508.2  

    ENSEMBL proteins: 
     ENSP00000357991   ENSP00000326489   ENSP00000355167   ENSP00000357983   ENSP00000401940  
     ENSP00000357989  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR003511 HORMA_DNA-bd

    Graphical View of Domain Structure for InterPro Entry Q86X24

    ProtoNet protein and cluster: Q86X24

    1 Blocks protein domain: IPB003511 DNA-binding HORMA

    UniProtKB/Swiss-Prot: HORM1_HUMAN, Q86X24
    Similarity: Contains 1 HORMA domain


    Find genes that share domains with HORMAD1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HORM1_HUMAN, Q86X24
    Function: Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that
    sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by
    increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation
    independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the
    female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome
    regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic
    prophase quality control in both sexes (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with HORMAD1           About GenesLikeMe


    Phenotypes:
         5 MGI mutant phenotypes (inferred from 4 alleles(MGI details for Hormad1):
     cellular  embryogenesis  endocrine/exocrine gland  homeostasis/metabolism  reproductive system 

    Find genes that share phenotypes with HORMAD1           About GenesLikeMe

    Animal Models:
         MGI mouse knock-outs for HORMAD1: Hormad1tm1.2Atot Hormad1tm1Rajk

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HORMAD1
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    HORM1_HUMAN, Q86X24: Nucleus (By similarity). Chromosome (By similarity). Note=Preferentially localizes to
    unsynapsed or desynapsed chromosomal regions during the prophase I stage of meiosis. TRIP13 is required for
    depletion from synapsed chromosomes. The expression of the phosphorylated form at Ser-377 is restricted to
    unsynapsed chromosomal regions (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton4
    nucleus4
    mitochondrion2
    cytosol1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005694chromosome ISS--
    GO:0005737cytoplasm ----
    GO:0045111intermediate filament cytoskeleton ----

    Find genes that share ontologies with HORMAD1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HORMAD1
    Interactions:

        Search GeneGlobe Interaction Network for HORMAD1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for HORMAD1 (ENSP000003551674) via UniProtKB, MINT, STRING, and/or I2D (see all 64)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    APOBEC4ENSP000003106224STRING: ENSP00000310622
    C1orf146ENSP000003594014STRING: ENSP00000359401
    CACYBPENSP000003566524STRING: ENSP00000356652
    CELA3AENSP000002901224STRING: ENSP00000290122
    COL11A1ENSP000003511634STRING: ENSP00000351163
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001824blastocyst development ISS--
    GO:0007126meiotic nuclear division ISS--
    GO:0007130synaptonemal complex assembly ISS--
    GO:0007283spermatogenesis ISS--
    GO:0030154cell differentiation IEA--

    Find genes that share ontologies with HORMAD1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HORMAD1 (HORM1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for HORMAD1 gene (2 alternative transcripts): 
    NM_001199829.1  NM_032132.4  

    Unigene Cluster for HORMAD1:

    HORMA domain containing 1
    Hs.298312  [show with all ESTs]
    Unigene Representative Sequence: NM_032132
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000368995(uc001evm.2) ENST00000322343 ENST00000361824 ENST00000470397
    ENST00000486497 ENST00000368987 ENST00000442853 ENST00000476530 ENST00000368993(uc001evk.2 uc001evl.2)

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    hsa-miR-522 hsa-miR-224* hsa-miR-374c hsa-miR-338-5p hsa-miR-548t hsa-miR-655 hsa-miR-493* hsa-miR-3143
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    Additional mRNA sequence: 

    AK097390.1 AK098633.1 AL136755.2 AY626344.1 BC033014.1 BC047406.1 CR533505.1 

    8 DOTS entries:

    DT.302948  DT.97786043  DT.75101119  DT.121426225  DT.102841846  DT.100751606  DT.121426240  DT.40208874 

    Selected AceView cDNA sequences (see all 51):

    BP370247 BC047406 BM554190 BP371325 AK097390 AK098633 BP371672 AA505930 
    AL136755 AY626344 BI829138 NM_032132 CD243828 BQ435604 BI561127 BI562548 
    AI652638 AL041831 AI732538 BG721909 CR533505 BC033014 AI791283 AA991355 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for HORMAD1    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15a · 15b · 15c · 15d · 15e
    SP1:              -                       -                                                                 -     -                           
    SP2:                                                                                                              -                           
    SP3:                                                                                                                                          
    SP4:                                                                                                  -     -     -                           
    SP5:                                                                                                        -                                 


    ECgene alternative splicing isoforms for HORMAD1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HORMAD1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATCTGGGAG
    HORMAD1 Expression
    About this image


    HORMAD1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Gonad
             XY Germ Cells Testis Cord
     
     Testis (Reproductive System)
             XY Germ Cells Testis Cord
     
     Ovary (Reproductive System)
             XX Germ Cells Ovigerous Cord
    HORMAD1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HORMAD1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.298312

    UniProtKB/Swiss-Prot: HORM1_HUMAN, Q86X24
    Tissue specificity: Testis-specific. Over-expressed in carcinomas

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for HORMAD1 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hormad11 , 5 HORMA domain containing 11, 5 86.37(n)1
    80.95(a)1
      3 (40.74 cM)5
    679811  NM_026489.21  NP_080765.11 
     955596775 
    chicken
    (Gallus gallus)
    Aves HORMAD11 HORMA domain containing 1 66.67(n)
    64.67(a)
      425071  XM_422864.3  XP_422864.2 
    lizard
    (Anolis carolinensis)
    Reptilia HORMAD16
    HORMA domain containing 1
    62(a)
    1 ↔ 1
    GL343862.1(43527-61301)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia hormad11 HORMA domain containing 1 64.57(n)
    58.38(a)
      100489965  XM_002935467.1  XP_002935513.1 
    zebrafish
    (Danio rerio)
    Actinopterygii CF997106.12   -- 74.05(n)    CF997106.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes HOP1(YIL072W)4 Meiosis-specific DNA binding protein that displays more   --   9(226602-228419) 854738  NP_012193.1 


    ENSEMBL Gene Tree for HORMAD1 (if available)
    TreeFam Gene Tree for HORMAD1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HORMAD1 gene
    HORMAD22  
    1 SIMAP similar gene for HORMAD1 using alignment to 2 protein entries:     HORM1_HUMAN (see all proteins):
    HORMAD2

    Find genes that share paralogs with HORMAD1           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for HORMAD1
    PGOHUM00000243245


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HORMAD1 (see all 408)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1512134761,2
    C--150671683(+) AATATC/GTAGTT 2 -- int10--------
    rs741249731,2
    C,F--150671814(+) TACTAG/CGAGGA 2 -- int12Minor allele frequency- C:0.08WA 120
    rs1886470741,2
    --150671817(+) TAGGAG/TGAGAC 2 -- int10--------
    rs1391527811,2
    --150671873(+) CTACTA/TCAGTT 2 -- int10--------
    rs1911733861,2
    --150671879(+) CAGTTC/TTGATC 2 -- int10--------
    rs176000201,2
    C,F,H--150671887(+) ATCTCT/CAGAAA 2 -- int110Minor allele frequency- C:0.03NA NS 944
    rs1824971351,2
    --150672041(+) CTGTCA/GCCAGG 2 -- int10--------
    rs125650381,2
    C,A,H--150672063(+) tggcgC/Tgatct 2 -- int10--------
    rs2017740341,2
    C--150672167(+) GCTAT-/TGTTTTT 2 -- int10--------
    rs341543011,2
    C--150672168(+) CTATT-/GTTTTT 2 -- int10--------

    HapMap Linkage Disequilibrium report for HORMAD1 (150670535 - 150693364 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for HORMAD1 (see all 14):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2717807CNV Deletion23290073
    esv3600CNV Deletion18987735
    esv2570262CNV Deletion19546169
    esv2238986CNV Deletion18987734
    esv1594619CNV Deletion17803354
    esv992009CNV Deletion20482838
    esv2482983CNV Deletion19546169
    esv2609983CNV Deletion19546169
    esv9188CNV Loss19470904
    nsv437158CNV Loss16327808

    Human Gene Mutation Database (HGMD): HORMAD1
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing HORMAD1
    DNA2.0 Custom Variant and Variant Library Synthesis for HORMAD1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609824    OMIM disorders: --


    Find genes that share disorders with HORMAD1           About GenesLikeMe


    Export disorders for HORMAD1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HORMAD1 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with HORMAD1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of CT46/HORMAD1, an immunogenic cancer/testis antigen encoding a putative meiosis-related protein. (PubMed id 15999985)1, 2, 3 Chen Y.-T.... Simpson A.J.G. (Cancer Immun. 2005)
    2. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (Genome Res. 2001)
    3. Restricted germ cell expression of a gene encoding a novel mammalian HORMA domain-containing protein. (PubMed id 15567723)1, 2, 9 Pangas S.A.... Rajkovic A. (Gene Expr. Patterns 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Genome-wide association study identifies genetic risk underlying primary rhegmatogenous retinal detachment. (PubMed id 23585552)1 Kirin M....Mitry D. (Hum. Mol. Genet. 2013)
    6. Biological significance of HORMA domain containing protein 1 (HORMAD1) in epithelial ovarian carcinoma. (PubMed id 22776561)1 Shahzad M.M....Sood A.K. (Cancer Lett. 2013)
    7. Single-nucleotide polymorphisms in HORMAD1 may be a risk factor for azoospermia caused by meiotic arrest in Japanese patients. (PubMed id 22407170)1 Miyamoto T....Sengoku K. (Asian J. Androl. 2012)
    8. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    9. Integrated profiling of basal and luminal breast cancers. (PubMed id 18089785)1 AdAclaA^de J....Chaffanet M. (Cancer Res. 2007)
    10. Systematic search for gastric cancer-specific genes based on SAGE data: melanoma inhibitory activity and matrix metalloproteinase-10 are novel prognostic factors in patients with gastric cancer. (PubMed id 16331256)1 Aung P.P....Yasui W. (Oncogene 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 84072 HGNC: 25245 AceView: NOHMA Ensembl:ENSG00000143452 euGenes: HUgn84072
    ECgene: HORMAD1 H-InvDB: HORMAD1

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HORMAD1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for HORMAD1 gene:
    Search GeneIP for patents involving HORMAD1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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