Aliases for HOOK2 Gene
Aliases for HOOK2 Gene
External Ids for HOOK2 Gene
- HGNC: 19885
- Entrez Gene: 29911
- Ensembl: ENSG00000095066
- OMIM: 607824
- UniProtKB: Q96ED9
Previous GeneCards Identifiers for HOOK2 Gene
- GC19M013005
- GC19M013096
- GC19M012719
- GC19M012734
- GC19M012873
- GC19M012446
- GC19M012766
- GC19M012769
- GC19M012770
- GC19M012771
- GC19M012772
Summaries for HOOK2 Gene
-
Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[supplied by OMIM, Apr 2004]
GeneCards Summary for HOOK2 Gene
HOOK2 (Hook Microtubule Tethering Protein 2) is a Protein Coding gene. GO annotations related to this gene include identical protein binding. An important paralog of this gene is HOOK3.
UniProtKB/Swiss-Prot for HOOK2 Gene
-
Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Contributes to the establishment and maintenance of centrosome function. May function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HOOK2 Gene
Genomics for HOOK2 Gene
Regulatory Elements for HOOK2 Gene
Enhancers for HOOK2 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around HOOK2 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the HOOK2 gene promoter:
Regulatory Element Products
Genomic Location for HOOK2 Gene
- Chromosome:
- 19
- Start:
- 12,763,003 bp from pter
- End:
- 12,872,740 bp from pter
- Size:
- 109,738 bases
- Orientation:
- Minus strand
Genomic View for HOOK2 Gene
Genes around HOOK2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19p13.13 by Ensembl
- 19p13.13 by Entrez Gene
- 19p13.13 by HGNC
HOOK2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HOOK2 Gene
Proteins for HOOK2 Gene
-
Protein details for HOOK2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96ED9-HOOK2_HUMAN
- Recommended name:
- Protein Hook homolog 2
- Protein Accession:
- Q96ED9
- O60562
Protein attributes for HOOK2 Gene
- Size:
- 719 amino acids
- Molecular mass:
- 83207 Da
- Quaternary structure:
-
- Self-associates. Component of the FTS/Hook/FHIP complex (FHF complex), composed of AKTIP/FTS, FAM160A2, and one or more members of the Hook family of proteins HOOK1, HOOK2, and HOOK3. May interact directly with AKTIP/FTS, HOOK1 and HOOK3. Associates with several subunits of the homotypic vesicular sorting complex (the HOPS complex) including VPS16 and VPS41; these interactions may be indirect. Interacts with CNTRL. Interacts with microtubules. Interacts with ZC3H14. Interacts with LRGUK (By similarity).
Protein Expression for HOOK2 Gene
Post-translational modifications for HOOK2 Gene
Other Protein References for HOOK2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for HOOK2
- Invitrogen Antibodies for HOOK2
- antibodies-online Antibodies for HOOK2: See all 16
- GeneTex HOOK2 antibody for HOOK2
-
Santa Cruz Biotechnology (SCBT) Antibodies for HOOK2
Protein Products
-
OriGene Purified Proteins for HOOK2
- Search Origene for MassSpec and Protein Over-expression Lysates for HOOK2
- Origene Custom Protein Services for HOOK2
- antibodies-online Proteins for HOOK2: See all 5
- Search antibodies-online for peptides
- Search GeneTex for Proteins for HOOK2
Assay Products
No data available for DME Specific Peptides for HOOK2 Gene
Domains & Families for HOOK2 Gene
Protein Domains for HOOK2 Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for HOOK2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q96ED9- Family:
-
- Belongs to the hook family.
No data available for Gene Families for HOOK2 Gene
Function for HOOK2 Gene
Molecular function for HOOK2 Gene
- UniProtKB/Swiss-Prot Function:
- Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Contributes to the establishment and maintenance of centrosome function. May function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 16189514 |
| GO:0008017 | microtubule binding | IBA | -- |
| GO:0042802 | identical protein binding | IPI | 18799622 |
| GO:0051959 | dynein light intermediate chain binding | IBA | -- |
Phenotypes for HOOK2 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for HOOK2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HOOK2 gene
- Search ViGene Biosciences for HOOK2
CRISPR Products
-
OriGene CRISPR knockouts for HOOK2
-
Santa Cruz Biotechnology (SCBT) CRISPR for HOOK2
- GenScript: Design CRISPR guide RNA sequences for HOOK2
miRNA for HOOK2 Gene
- miRTarBase miRNAs that target HOOK2
miRNA Products
- Search ViGene Biosciences for HOOK2
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HOOK2
- Browse OriGene Inhibitory RNA Products For HOOK2
-
ViGene Biosciences ready-to-package AAV shRNAs for HOOK2 gene
Clone Products
- Sino Biological Human cDNA Clone for HOOK2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for HOOK2
Cell Line Products
-
Horizon Cell Lines for HOOK2
-
ViGene Biosciences adenoviral particle packaged cDNA for HOOK2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for HOOK2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HOOK2 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for HOOK2 Gene
Localization for HOOK2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for HOOK2 Gene
- Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Cytoplasm, cytoskeleton. Note=Colocalizes with aggresomes, which are aggregates of misfolded proteins, at the centrosome. Also localizes to punctate cytoplasmic foci which do not appear to overlap with early or late endosomes, the endoplasmic reticulum, the Golgi complex, multivesicular bodies (MVBs), lysosomes, or mitochondria. Often found in close association with microtubules.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| cytosol | 5 |
| nucleus | 2 |
| mitochondrion | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005813 | centrosome | IDA | 17140400 |
| GO:0005815 | microtubule organizing center | IEA | -- |
| GO:0005829 | cytosol | IDA | -- |
| GO:0005856 | cytoskeleton | IEA | -- |
Pathways & Interactions for HOOK2 Gene
No Data Available
Interacting Proteins for HOOK2 Gene
Selected Interacting proteins:
ENSP00000380785
Q96ED9-HOOK2_HUMAN
for HOOK2 Gene via
STRING
IID
MINT
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006810 | transport | IEA | -- |
| GO:0006897 | endocytosis | TAS | 9927460 |
| GO:0007032 | endosome organization | IMP | 18799622 |
| GO:0007040 | lysosome organization | IMP | 18799622 |
| GO:0008333 | endosome to lysosome transport | IMP | 18799622 |
No data available for Pathways by source for HOOK2 Gene
Transcripts for HOOK2 Gene
mRNA/cDNA for HOOK2 Gene
- (13) REFSEQ mRNAs :
- (2) Additional mRNA sequences :
- (157) Selected AceView cDNA sequences:
- (24) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for HOOK2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for HOOK2
-
Santa Cruz Biotechnology (SCBT) CRISPR for HOOK2
- GenScript: Design CRISPR guide RNA sequences for HOOK2
miRNA Products
- Search ViGene Biosciences for HOOK2
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HOOK2
- Browse OriGene Inhibitory RNA Products For HOOK2
-
ViGene Biosciences ready-to-package AAV shRNAs for HOOK2 gene
Clone Products
- Sino Biological Human cDNA Clone for HOOK2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for HOOK2
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | · | 4d | · | 4e | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b | ^ | 17a | · |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: |
| ExUns: | 17b | ^ | 18 | ^ | 19a | · | 19b | ^ | 20a | · | 20b | ^ | 21 | ^ | 22 | ^ | 23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||
| SP2: | - | - | |||||||||||||||
| SP3: | |||||||||||||||||
| SP4: | |||||||||||||||||
| SP5: | |||||||||||||||||
| SP6: | |||||||||||||||||
| SP7: | |||||||||||||||||
| SP8: | |||||||||||||||||
| SP9: | |||||||||||||||||
| SP10: |
Expression for HOOK2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Skeletal Muscle (Muscoskeletal System)
- Mononuclear Myocytes Hyoid Arch Muscles
- Mononuclear Myocytes Mandibular Arch Muscles
- Muscle Progenitor Cells Mandibular Arch Muscles
- Muscle Progenitor Cells Hyoid Arch Muscles
- Brain (Nervous System)
- Gut Tube (Gastrointestinal Tract)
-
Testis (Reproductive System)
- Leydig Cells Testis Interstitium
- Thyroid (Endocrine System)
- Intestine (Gastrointestinal Tract)
- Pancreas (Endocrine System)
- Ovary (Reproductive System)
-
Adipose (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for HOOK2 Gene
This gene is overexpressed in Pituitary (x4.2).
This gene is overexpressed in Bone (63.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for HOOK2 Gene
NURSA nuclear receptor signaling pathways regulating expression of HOOK2 Gene:
HOOK2SOURCE GeneReport for Unigene cluster for HOOK2 Gene:
Hs.30792Evidence on tissue expression from TISSUES for HOOK2 Gene
- Liver(4.1)
Primer Products
-
OriGene qPCR primer pairs for HOOK2
-
OriGene qPCR primer pairs and template standards for HOOK2
No data available for Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for HOOK2 Gene
Orthologs for HOOK2 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | HOOK2 35 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | HOOK2 35 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | HOOK2 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Hook2 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Hook2 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | HOOK2 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | HOOK2 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | HOOK2 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | hook2 34 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.1897 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | hook2 34 35 |
|
||
| zgc66419 34 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | hk 35 |
|
OneToMany |
- Species where no ortholog for HOOK2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for HOOK2 Gene
(11) SIMAP similar genes for HOOK2 Gene using alignment to 9 proteins:
Variants for HOOK2 Gene
| SNP ID | Clin | Chr 19 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000203641 | -- | 12,766,879(+) | CGCCC(A/G)GTCGT | intron-variant | |
| rs1000217245 | -- | 12,763,973(+) | AAGCA(G/T)GAGCC | intron-variant | |
| rs1000249954 | -- | 12,779,222(+) | GCTGA(C/T)TCAAC | upstream-variant-2KB | |
| rs1000891444 | -- | 12,777,440(+) | GCGCC(A/T)CTGCA | intron-variant, upstream-variant-2KB | |
| rs1001137810 | -- | 12,776,272(+) | GGATG(A/C)TAAAG | intron-variant, upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv138n111 | CNV | deletion | 26073780 |
| esv2667754 | CNV | deletion | 23128226 |
| nsv1160586 | CNV | duplication | 26073780 |
| nsv953977 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
71.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
8.34;
85.35% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for HOOK2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- HOOK2
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HOOK2 Gene
Disorders for HOOK2 Gene
Relevant External Links for HOOK2
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- HOOK2
No disorders were found for HOOK2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HOOK2 Gene
Publications for HOOK2 Gene
- Genetic analysis of hook, a gene required for endocytic trafficking in Drosophila. (PMID: 9927460) Kraemer H. … Phistry M. (Genetics 1999) 2 3 4 64
- SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans. (PMID: 19273536) Guthrie C.R. … Kraemer B.C. (Hum. Mol. Genet. 2009) 3 4 64
- An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex. (PMID: 18799622) Xu L. … Harper J.W. (Mol. Biol. Cell 2008) 3 4 64
- Hook2 contributes to aggresome formation. (PMID: 17540036) Szebenyi G. … Kraemer H. (BMC Cell Biol. 2007) 3 4 64
- Hook2 localizes to the centrosome, binds directly to centriolin/CEP110 and contributes to centrosomal function. (PMID: 17140400) Szebenyi G. … Kraemer H. (Traffic 2007) 3 4 64
Products for HOOK2 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for HOOK2
- Search Origene for MassSpec and Protein Over-expression Lysates for HOOK2
- Origene Custom Protein Services for HOOK2
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for HOOK2
- Browse OriGene Inhibitory RNA Products For HOOK2
- OriGene qPCR primer pairs and template standards for HOOK2
- OriGene qPCR primer pairs for HOOK2
- OriGene CRISPR knockouts for HOOK2
- OriGene ORF clones in human for HOOK2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For HOOK2
- GenScript: Next-day shipping cDNA ORF clone for HOOK2 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for HOOK2
- GenScript Custom Assay Services for HOOK2
- GenScript Custom overexpressing Cell Line Services for HOOK2
- GenScript: Design CRISPR guide RNA sequences for HOOK2
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for HOOK2
- Sino Biological Human cDNA Clone for HOOK2
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for HOOK2
- Novus Biologicals proteins and lysates for HOOK2
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Addgene plasmids for HOOK2
- antibodies-online Antibodies for HOOK2: See all 16
- Search antibodies-online for kits
- antibodies-online Proteins for HOOK2: See all 5
- Search antibodies-online for peptides
- GeneTex HOOK2 antibody for HOOK2
- Search GeneTex for Proteins for HOOK2
- ViGene Biosciences adenoviral particle packaged cDNA for HOOK2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for HOOK2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for HOOK2 gene
- Search ViGene Biosciences for HOOK2
- Santa Cruz Biotechnology (SCBT) Antibodies for HOOK2
- Search Santa Cruz Biotechnology (SCBT) for HOOK2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for HOOK2
- Horizon Cell Lines for HOOK2
- Cyagen custom Knockout/knockin (KOKI) mouse models for HOOK2
- VectorBuilder custom plasmid, inducible vectors for HOOK2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HOOK2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for HOOK2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer