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HOMEZ Gene

protein-coding   GIFtS: 48
GCID: GC14M023742

Homeobox And Leucine Zipper Encoding

(Previous name: KIAA1443)
(Previous symbol: KIAA1443)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Homeobox And Leucine Zipper Encoding1 2
KIAA14431 2 3
Homeodomain Leucine Zipper-Containing Factor2 3
Homeobox And Leucine Zipper Protein Homez2

External Ids:    HGNC: 201641   Entrez Gene: 575942   Ensembl: ENSG000002152717   OMIM: 6081195   UniProtKB: Q8IX153   

Export aliases for HOMEZ gene to outside databases

Previous GC identifers: GC14M022813 GC14M003859


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for HOMEZ Gene:
HOMEZ (homeobox and leucine zipper encoding) is a protein-coding gene. Diseases associated with HOMEZ include neuronitis. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZHX2.

UniProtKB/Swiss-Prot: HOMEZ_HUMAN, Q8IX15
Function: May function as a transcriptional regulator




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000014.9  NC_018925.2  NT_026437.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the HOMEZ gene promoter:
         AREB6   STAT1   Sp1   Lmo2   CUTL1   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHOMEZ promoter sequence
   Search Chromatin IP Primers for HOMEZ

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HOMEZ


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q11.2   Ensembl cytogenetic band:  14q11.2   HGNC cytogenetic band: 14q11.2

HOMEZ Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HOMEZ gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M023742:  view genomic region     (about GC identifiers)

Start:
23,741,666 bp from pter      End:
23,768,656 bp from pter
Size:
26,991 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: HOMEZ_HUMAN, Q8IX15 (See protein sequence)
Recommended Name: Homeobox and leucine zipper protein Homez  
Size: 550 amino acids; 61240 Da
Subunit: Homodimer or heterodimer (Potential). Interacts with HOXC8
Caution: It is uncertain whether Met-1 or Met-25 is the initiator
Sequence caution: Sequence=AAN76991.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAA92681.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
2 PDB 3D structures from and Proteopedia for HOMEZ:
2ECC (3D)        2YS9 (3D)    
Secondary accessions: A1L445 Q6P049 Q86XB6 Q9P2A5

Explore the universe of human proteins at neXtProt for HOMEZ: NX_Q8IX15

Explore proteomics data for HOMEZ at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys230
  • Modification sites at PhosphoSitePlus

  • See HOMEZ Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_065885.2  
    ENSEMBL proteins: 
     ENSP00000350049   ENSP00000453979   ENSP00000475307   ENSP00000475773   ENSP00000406579  

    HOMEZ Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for HOMEZ
    OriGene Custom MassSpec
    OriGene Custom Protein Services for HOMEZ
    GenScript Custom Purified and Recombinant Proteins Services for HOMEZ
    Novus Biologicals HOMEZ Proteins
    Novus Biologicals HOMEZ Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for HOMEZ

    HOMEZ Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for HOMEZ
    OriGene Custom Antibody Services for HOMEZ
    Novus Biologicals HOMEZ Antibodies
    Abcam antibodies for HOMEZ
    Cloud-Clone Corp. Antibodies for HOMEZ
    ThermoFisher Antibodies for HOMEZ
    LSBio Antibodies in human, mouse, rat for HOMEZ

    HOMEZ Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for HOMEZ
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for HOMEZ
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for HOMEZ
    Cloud-Clone Corp. CLIAs for HOMEZ


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZFHX: Homeoboxes / ZF class

    3 InterPro protein domains:
     IPR008422 Homeobox_KN_domain
     IPR001356 Homeobox_dom
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry Q8IX15

    ProtoNet protein and cluster: Q8IX15

    UniProtKB/Swiss-Prot: HOMEZ_HUMAN, Q8IX15
    Similarity: Contains 2 homeobox DNA-binding domains


    HOMEZ for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HOMEZ_HUMAN, Q8IX15
    Function: May function as a transcriptional regulator

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0043565sequence-specific DNA binding IEA--
         
    HOMEZ for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Homez (no phenotypes)

    HOMEZ for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HOMEZ
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for HOMEZ

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HOMEZ
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HOMEZ

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat HOMEZ using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HOMEZ (see all 20):
    hsa-miR-642a hsa-miR-125a-5p hsa-miR-323b-3p hsa-miR-624 hsa-miR-570 hsa-miR-2115 hsa-miR-125b hsa-miR-520g
    SwitchGear 3'UTR luciferase reporter plasmidHOMEZ 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for HOMEZ
    Predesigned siRNA for gene silencing in human, mouse, rat HOMEZ

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for HOMEZ

    Clone
    Products:
         
    OriGene clones in human, mouse for HOMEZ (see all 9)
    OriGene ORF clones in mouse, rat for HOMEZ
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: HOMEZ (NM_020834)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HOMEZ
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HOMEZ

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for HOMEZ
    Browse ESI BIO Cell Lines and PureStem Progenitors for HOMEZ 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HOMEZ


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    HOMEZ_HUMAN, Q8IX15: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2
    golgi apparatus1
    peroxisome1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm IDA--

    HOMEZ for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HOMEZ
    Interactions:

        Search GeneGlobe Interaction Network for HOMEZ

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for HOMEZ (Q8IX153 ENSP000003500494) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HOXC8P312733, ENSP000000405844I2D: score=1 STRING: ENSP00000040584
    SUMO2ENSP000004059654STRING: ENSP00000405965
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated ----

    HOMEZ for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HOMEZ

    1 Novoseek inferred chemical compound relationship for HOMEZ gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    leucine 55.7 5 11302705 (3), 15595839 (1), 15469713 (1)



    HOMEZ for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for HOMEZ gene: 
    NM_020834.2  

    Unigene Cluster for HOMEZ:

    Homeobox and leucine zipper encoding
    Hs.632332  [show with all ESTs]
    Unigene Representative Sequence: NM_020834
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000357460(uc001wja.2 uc001wjb.2) ENST00000561013 ENST00000606731
    ENST00000606006 ENST00000561396 ENST00000558278 ENST00000431326
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat HOMEZ using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HOMEZ (see all 20):
    hsa-miR-642a hsa-miR-125a-5p hsa-miR-323b-3p hsa-miR-624 hsa-miR-570 hsa-miR-2115 hsa-miR-125b hsa-miR-520g
    SwitchGear 3'UTR luciferase reporter plasmidHOMEZ 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for HOMEZ
    Predesigned siRNA for gene silencing in human, mouse, rat HOMEZ
    Clone
    Products:
         
    OriGene clones in human, mouse for HOMEZ (see all 9)
    OriGene ORF clones in mouse, rat for HOMEZ
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: HOMEZ (NM_020834)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HOMEZ
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HOMEZ
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for HOMEZ
    OriGene qSTAR qPCR primer pairs in human, mouse for HOMEZ
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat HOMEZ
      QuantiTect SYBR Green Assays in human, mouse, rat HOMEZ
      QuantiFast Probe-based Assays in human, mouse, rat HOMEZ

    Additional mRNA sequence: 

    AB037864.1 AF463523.1 AK296927.1 AK301849.1 AK302788.1 BC045733.1 BC130392.1 

    9 DOTS entries:

    DT.443680  DT.91871587  DT.92423077  DT.100020798  DT.65285354  DT.436898  DT.120748362  DT.65285353 
    DT.99976616 

    Selected AceView cDNA sequences (see all 203):

    BC065835 R73365 CR619320 AI685035 AF463523 BX161476 AI208470 AA653734 
    CA394118 BE264625 BF510916 NM_020834 AI023932 AA737538 AK091943 AI243851 
    AA916857 BQ064437 BU686902 BM353948 AW449317 BX248758 AI264023 AI128336 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HOMEZ expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGCAACTAAA
    HOMEZ Expression
    About this image

    HOMEZ Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HOMEZ Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.632332

    UniProtKB/Swiss-Prot: HOMEZ_HUMAN, Q8IX15
    Tissue specificity: Ubiquitous. Strongly expressed in adult testis and kidney as well as fetal lung and kidney

        Custom PCR Arrays for HOMEZ
    Primer
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    OriGene qPCR primer pairs and template standards for HOMEZ
    OriGene qSTAR qPCR primer pairs in human, mouse for HOMEZ
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat HOMEZ
    QuantiTect SYBR Green Assays in human, mouse, rat HOMEZ
    QuantiFast Probe-based Assays in human, mouse, rat HOMEZ
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HOMEZ

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for HOMEZ gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Homez1 , 5 homeodomain leucine zipper-encoding gene1, 5 80.21(n)1
    77.71(a)1
      14 (27.96 cM)5
    2390991  NM_183174.31  NP_898997.21 
     548527365 
    lizard
    (Anolis carolinensis)
    Reptilia HOMEZ6
    homeobox and leucine zipper encoding
    48(a)
    1 ↔ 1
    GL343776.1(10884-12347)
    zebrafish
    (Danio rerio)
    Actinopterygii homez6
    HOMEZ (1 of 2)6
    homeobox and leucine zipper encoding
    18(a)
    14(a)
    1 ↔ many
    1 ↔ many
    2(37974150-37978416) ENSDARG00000054304
    7(25174456-25180979) ENSDARG00000024598


    ENSEMBL Gene Tree for HOMEZ (if available)
    TreeFam Gene Tree for HOMEZ (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HOMEZ gene
    ZHX22  ZHX32  ZHX12  

    HOMEZ for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HOMEZ (see all 330)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs762974811,2
    C,F--23742355(+) ATTTCC/GTACAA 1 -- ds50011Minor allele frequency- G:0.01WA 118
    rs1859227911,2
    --23742454(+) CTGTTC/TCATTT 1 -- ds50010--------
    rs1488219501,2
    C--23742486(+) GGATAC/TACTGT 1 -- ds50010--------
    rs2021556971,2
    --23742492(+) ACTGT-/CCCATT 1 -- ds50010--------
    rs1469205541,2
    --23742504(+) CCAATA/GTTAAC 1 -- ds50010--------
    rs1380171321,2
    C--23742539(+) TATTAC/TACTTT 1 -- ds50010--------
    rs1434930871,2
    --23742726(+) TGGGCG/TAACAA 1 -- ds50010--------
    rs777567491,2
    C,F--23742928(+) TTCTGG/CTACTC 1 -- ut311Minor allele frequency- C:0.01EA 120
    rs170936071,2
    C,F,H--23743043(+) GAAGCC/GTCAGA 1 -- ut319Minor allele frequency- G:0.05NA NS EA WA 682
    rs1912174241,2
    --23743051(+) AGAAAC/TTTTAG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for HOMEZ (23741666 - 23768656 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for HOMEZ: --
    Human Gene Mutation Database (HGMD): HOMEZ
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing HOMEZ
    DNA2.0 Custom Variant and Variant Library Synthesis for HOMEZ

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608119    OMIM disorders: --

    1 disease for HOMEZ:    
    About MalaCards
    neuronitis


    HOMEZ for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: HOMEZ (1 document)

    Export disorders for HOMEZ gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HOMEZ gene, integrated from 10 sources (see all 21):
    (articles sorted by number of sources associating them with HOMEZ)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Homez, a homeobox leucine zipper gene specific to the vertebrate lineage. (PubMed id 12925734)1, 2, 3 Bayarsaihan D.... Ruddle F.H. (Proc. Natl. Acad. Sci. U.S.A. 2003)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)1, 2 Nagase T.... Ohara O. (DNA Res. 2000)
    4. Identification of human protein interaction domains using an ORFeome-based yeast two-hybrid fragment library. (PubMed id 23718855)1 Waaijers S....Boxem M. (J. Proteome Res. 2013)
    5. Identification of two novel mutations of the HOMEZ gene in Chinese patients with isolated ventricular septal defect. (PubMed id 23574532)1 Xuan C....He G.W. (Genet Test Mol Biomarkers 2013)
    6. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    7. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    8. Consanguinity mapping of congenital heart disease in a South Indian population. (PubMed id 20422016)1 McGregor T.L....Morgan T.M. (PLoS ONE 2010)
    9. System-wide changes to SUMO modifications in response to heat shock. (PubMed id 19471022)1 Golebiowski F....Hay R.T. (Sci Signal 2009)
    10. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57594 HGNC: 20164 AceView: KIAA1443andPPP1R3E Ensembl:ENSG00000215271 euGenes: HUgn57594
    ECgene: HOMEZ H-InvDB: HOMEZ

    (According to HUGE)
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    HUGE: KIAA1443

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HOMEZ Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for HOMEZ gene:
    Search GeneIP for patents involving HOMEZ

    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     OriGene Antibodies for HOMEZ   OriGene RNAi products in human, mouse, rat for HOMEZ  
     OriGene qPCR primer pairs and template standards for HOMEZ   OriGene Protein Over-expression Lysate for HOMEZ  
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     Block miRNA regulation of human, mouse, rat HOMEZ using miScript Target Protectors SeqTarget long-range PCR primers for resequencing HOMEZ
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HOMEZ Predesigned siRNA for gene silencing in human, mouse, rat HOMEZ
     QuantiFast Probe-based Assays in human, mouse, rat HOMEZ QuantiTect SYBR Green Assays in human, mouse, rat HOMEZ
     Custom PCR Arrays for HOMEZ Search Chromatin IP Primers for HOMEZ
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     Regulatory tfbs in HOMEZ promoter
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     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
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     Browse ESI BIO Cell Lines and PureStem Progenitors for HOMEZ
     Gene Synthesis
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     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HOMEZ
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HOMEZ
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     LSBio Antibodies in human, mouse, rat for HOMEZ
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     Browse compounds at ApexBio
           
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