Aliases for HOMER1 Gene
Aliases for HOMER1 Gene
External Ids for HOMER1 Gene
- HGNC: 17512
- Entrez Gene: 9456
- Ensembl: ENSG00000152413
- OMIM: 604798
- UniProtKB: Q86YM7
Previous GeneCards Identifiers for HOMER1 Gene
- GC05M078910
- GC05M078708
- GC05M078753
- GC05M078755
- GC05M078705
- GC05M073877
Summaries for HOMER1 Gene
-
This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. [provided by RefSeq, Jul 2008]
GeneCards Summary for HOMER1 Gene
HOMER1 (Homer Scaffolding Protein 1) is a Protein Coding gene. Among its related pathways are Protein-protein interactions at synapses and Circadian rythm related genes. GO annotations related to this gene include identical protein binding and receptor binding. An important paralog of this gene is HOMER2.
UniProtKB/Swiss-Prot for HOMER1 Gene
-
Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabotropic glutamate function. Isoform 3, may be involved in the structural changes that occur at synapses during long-lasting neuronal plasticity and development.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HOMER1 Gene
Genomics for HOMER1 Gene
Regulatory Elements for HOMER1 Gene
Enhancers for HOMER1 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH05G079560 | 1.3 | FANTOM5 Ensembl ENCODE | 10.6 | -47.1 | -47135 | 1.2 | PKNOX1 IRF2 L3MBTL2 HLF BACH1 ZNF175 CEBPB JUNB PTTG1 CEBPG | CMYA5 HOMER1 ENSG00000250258 THBS4 CTD-2201I18.1 PAPD4 ENSG00000277818 LOC105379047 |
| GH05G079556 | 1 | Ensembl ENCODE | 11 | -42.2 | -42184 | 0.4 | CTCF CEBPG ZNF2 RAD21 YY1 ZNF507 SCRT2 ZNF143 SMC3 NR2F6 | HOMER1 THBS4 CTD-2201I18.1 ENSG00000277818 LOC105379047 |
| GH05G079546 | 1.3 | FANTOM5 ENCODE | 5.5 | -33.5 | -33542 | 1.8 | PKNOX1 FOXA2 FEZF1 RAD21 RARA FOS RCOR1 CREM ZNF263 NFYC | HOMER1 PAPD4 CMYA5 LOC105379047 ENSG00000277818 |
| GH05G079562 | 0.5 | ENCODE | 10.6 | -48.4 | -48366 | 0.1 | PRDM6 FEZF1 ZEB2 EBF1 | HOMER1 CMYA5 ENSG00000250258 THBS4 CTD-2201I18.1 ENSG00000277818 LOC105379047 |
| GH05G079447 | 0.5 | ENCODE | 5.3 | +65.5 | 65454 | 1.6 | MAFF ZNF316 CEBPB MAFK | HOMER1 GC05M079453 LOC101929201 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around HOMER1 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the HOMER1 gene promoter:
Regulatory Element Products
Genomic Location for HOMER1 Gene
- Chromosome:
- 5
- Start:
- 79,372,636 bp from pter
- End:
- 79,514,217 bp from pter
- Size:
- 141,582 bases
- Orientation:
- Minus strand
Genomic View for HOMER1 Gene
Genes around HOMER1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 5q14.1 by Ensembl
- 5q14.1 by Entrez Gene
- 5q14.1 by HGNC
HOMER1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HOMER1 Gene
Proteins for HOMER1 Gene
-
Protein details for HOMER1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q86YM7-HOME1_HUMAN
- Recommended name:
- Homer protein homolog 1
- Protein Accession:
- Q86YM7
- B2R688
- O96003
- Q86YM5
Protein attributes for HOMER1 Gene
- Size:
- 354 amino acids
- Molecular mass:
- 40277 Da
- Quaternary structure:
-
- Interacts with GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. Interacts with IFT57 and OPHN1. Isoform 1 encodes a coiled-coil structure that mediates homo- and heteromultimerization.
Protein Expression for HOMER1 Gene
Post-translational modifications for HOMER1 Gene
Other Protein References for HOMER1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for HOMER1
- R&D Systems Antibodies for HOMER1 (HOMER1)
- Cell Signaling Technology (CST) Antibodies for HOMER1 (HOMER1)
-
Custom Antibody ServicesOriGene Antibodies for HOMER1
- Novus Biologicals Antibodies for HOMER1
-
Abcam antibodies for HOMER1
- Invitrogen Antibodies for HOMER1
- antibodies-online Antibodies for HOMER1: See all 75
- GeneTex HOMER1 antibody for HOMER1
-
Santa Cruz Biotechnology (SCBT) Antibodies for HOMER1
Protein Products
-
OriGene Purified Proteins for HOMER1
- Search Origene for MassSpec and Protein Over-expression Lysates for HOMER1
- Origene Custom Protein Services for HOMER1
- ProSpec Recombinant Proteins for HOMER1
- antibodies-online Proteins for HOMER1: See all 12
- Search antibodies-online for peptides
- Search GeneTex for Proteins for HOMER1
Assay Products
- antibodies-online Kits for HOMER1: See all 1
No data available for DME Specific Peptides for HOMER1 Gene
Domains & Families for HOMER1 Gene
Gene Families for HOMER1 Gene
Protein Domains for HOMER1 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for HOMER1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q86YM7UniProtKB/Swiss-Prot:
HOME1_HUMAN :- The WH1 domain interacts with the PPXXF motif in GRM1, GRM5, RYR1, RYR2, ITPR1, SHANK 1 and SHANK3.
- Belongs to the Homer family.
- Domain:
-
- The WH1 domain interacts with the PPXXF motif in GRM1, GRM5, RYR1, RYR2, ITPR1, SHANK 1 and SHANK3.
- Family:
-
- Belongs to the Homer family.
Function for HOMER1 Gene
Molecular function for HOMER1 Gene
- UniProtKB/Swiss-Prot Function:
- Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabotropic glutamate function. Isoform 3, may be involved in the structural changes that occur at synapses during long-lasting neuronal plasticity and development.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 16189514 |
| GO:0035591 | signaling adaptor activity | IC | 14505576 |
| GO:0044325 | ion channel binding | IPI | 14505576 |
Phenotypes for HOMER1 Gene
- MGI mutant phenotypes for HOMER1:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for HOMER1:
Animal Models for HOMER1 Gene
- MGI Knock Outs for HOMER1:
-
- Homer1 tm1Mhd
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for HOMER1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HOMER1 gene
- Search ViGene Biosciences for HOMER1
CRISPR Products
-
OriGene CRISPR knockouts for HOMER1
-
Santa Cruz Biotechnology (SCBT) CRISPR for HOMER1
- GenScript: Design CRISPR guide RNA sequences for HOMER1
miRNA for HOMER1 Gene
- miRTarBase miRNAs that target HOMER1
miRNA Products
- Search ViGene Biosciences for HOMER1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HOMER1
- Browse OriGene Inhibitory RNA Products For HOMER1
-
ViGene Biosciences ready-to-package AAV shRNAs for HOMER1 gene
Clone Products
- Sino Biological Human cDNA Clone for HOMER1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
Horizon Cell Lines for HOMER1
-
ViGene Biosciences adenoviral particle packaged cDNA for HOMER1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for HOMER1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HOMER1 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for HOMER1 Gene
Localization for HOMER1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for HOMER1 Gene
- Cytoplasm. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse. Note=Isoform 1 inhibits surface expression of GRM5 causing it to be retained in the endoplasmic reticulum. {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| plasma membrane | 4 |
| nucleus | 2 |
| endoplasmic reticulum | 2 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
| GO:0005886 | plasma membrane | IEA | -- |
| GO:0014069 | postsynaptic density | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
Pathways & Interactions for HOMER1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Protein-protein interactions at synapses | ||
| 2 | FoxO signaling pathway | ||
| 3 | Circadian entrainment | ||
| 4 | Neuroscience | ||
| 5 | Transmission across Chemical Synapses |
.62
|
|
Pathways by source for HOMER1 Gene
1 Cell Signaling Technology pathway for HOMER1 Gene
2 BioSystems pathways for HOMER1 Gene
3 Reactome pathways for HOMER1 Gene
2 KEGG pathways for HOMER1 Gene
Interacting Proteins for HOMER1 Gene
Selected Interacting proteins:
Q86YM7-HOME1_HUMAN
ENSP00000334382
for HOMER1 Gene via
MINT
STRING
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003009 | skeletal muscle contraction | IEA | -- |
| GO:0007206 | phospholipase C-activating G-protein coupled glutamate receptor signaling pathway | TAS | 9808459 |
| GO:0007268 | chemical synaptic transmission | TAS | 9808458 |
| GO:0009967 | positive regulation of signal transduction | IC | 14505576 |
| GO:0048148 | behavioral response to cocaine | IEA | -- |
No data available for SIGNOR curated interactions for HOMER1 Gene
Transcripts for HOMER1 Gene
mRNA/cDNA for HOMER1 Gene
- (4) REFSEQ mRNAs :
- (11) Additional mRNA sequences :
- (119) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for HOMER1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for HOMER1
-
Santa Cruz Biotechnology (SCBT) CRISPR for HOMER1
- GenScript: Design CRISPR guide RNA sequences for HOMER1
miRNA Products
- Search ViGene Biosciences for HOMER1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HOMER1
- Browse OriGene Inhibitory RNA Products For HOMER1
-
ViGene Biosciences ready-to-package AAV shRNAs for HOMER1 gene
Clone Products
- Sino Biological Human cDNA Clone for HOMER1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||
| SP2: | - | - | - | - | |||||||||||||||||
| SP3: | - | - | - | - | |||||||||||||||||
| SP4: |
Expression for HOMER1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Skeletal Muscle (Muscoskeletal System)
- Mononuclear Myocytes Hyoid Arch Muscles
- Mononuclear Myocytes Mandibular Arch Muscles
- Myoblasts Mandibular Arch Muscles
- Myoblasts Hyoid Arch Muscles
- Brain (Nervous System)
- Neural Tube (Nervous System)
- Gut Tube (Gastrointestinal Tract)
mRNA differential expression in normal tissues according to GTEx for HOMER1 Gene
This gene is overexpressed in Brain - Anterior cingulate cortex (BA24) (x4.5) and Brain - Frontal Cortex (BA9) (x4.2).
This gene is overexpressed in Brain (18.7), Lung (16.9), Fetal Brain (10.3), and Frontal cortex (9.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for HOMER1 Gene
NURSA nuclear receptor signaling pathways regulating expression of HOMER1 Gene:
HOMER1SOURCE GeneReport for Unigene cluster for HOMER1 Gene:
Hs.591761Evidence on tissue expression from TISSUES for HOMER1 Gene
- Nervous system(4.8)
- Pancreas(4.1)
- Muscle(2.1)
Primer Products
-
OriGene qPCR primer pairs for HOMER1
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for HOMER1 Gene
Orthologs for HOMER1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | HOMER1 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | HOMER1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | HOMER1 34 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | HOMER1 35 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Homer1 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Homer1 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | HOMER1 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | HOMER1 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | HOMER1 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | homer1 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | HOMER1 35 |
|
OneToOne | |
| homer1 34 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | homer 35 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToMany |
- Species where no ortholog for HOMER1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for HOMER1 Gene
(2) SIMAP similar genes for HOMER1 Gene using alignment to 3 proteins:
Variants for HOMER1 Gene
| SNP ID | Clin | Chr 05 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000013082 | -- | 79,387,305(+) | AAATA(C/T)TTTTG | intron-variant | |
| rs1000074143 | -- | 79,380,648(+) | ACATA(C/G)CATCA | intron-variant | |
| rs1000084729 | -- | 79,388,628(+) | GGTAA(A/G)CAAAA | intron-variant | |
| rs1000087037 | -- | 79,478,434(+) | CTGTA(A/G)TCCTA | intron-variant | |
| rs1000112759 | -- | 79,460,172(+) | TTTAG(A/G)AAGAT | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2730351 | CNV | deletion | 23290073 |
| esv2730352 | CNV | deletion | 23290073 |
| esv2730353 | CNV | deletion | 23290073 |
| esv3381279 | CNV | insertion | 20981092 |
| esv3605531 | CNV | gain | 21293372 |
| esv3890659 | CNV | gain | 25118596 |
| nsv1126063 | CNV | deletion | 24896259 |
| nsv462218 | CNV | gain | 19166990 |
| nsv472347 | CNV | novel sequence insertion | 20440878 |
| nsv598742 | CNV | gain | 21841781 |
Residual Variation Intolerance Score:
22.4% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for HOMER1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- HOMER1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HOMER1 Gene
Disorders for HOMER1 Gene
Relevant External Links for HOMER1
No disorders were found for HOMER1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HOMER1 Gene
Publications for HOMER1 Gene
- Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins. (PMID: 9808458) Xiao B. … Worley P.F. (Neuron 1998) 2 3 4 64
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
- No association of alcohol dependence with HOMER 1 and 2 genetic variants. (PMID: 20333726) Preuss U.W. … Zill P. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2010) 3 46 64
- Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. (PMID: 19086053) GratacA^s M. … Carracedo A. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2009) 3 46 64
- HOMER1 promoter analysis in Parkinson's disease: association study with psychotic symptoms. (PMID: 19648775) De Luca V. … Quattrone A. (Neuropsychobiology 2009) 3 46 64
Products for HOMER1 Gene
- R&D Systems Antibodies for HOMER1 (HOMER1)
- Browse R&D Systems for Human Recombinant Proteins
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- Custom Antibody ServicesOriGene Antibodies for HOMER1
- Browse OriGene ELISA Kits
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- GenScript: Design CRISPR guide RNA sequences for HOMER1
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- Cell Signaling Technology (CST) Antibodies for HOMER1 (HOMER1)
- Search for Antibodies & Assays
- Sino Biological Human cDNA Clone for HOMER1
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- Novus Biologicals Antibodies for HOMER1
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- ProSpec Recombinant Proteins for HOMER1
- antibodies-online Antibodies for HOMER1: See all 75
- antibodies-online Kits for HOMER1: See all 1
- antibodies-online Proteins for HOMER1: See all 12
- Search antibodies-online for peptides
- GeneTex HOMER1 antibody for HOMER1
- Search GeneTex for Proteins for HOMER1
- ViGene Biosciences adenoviral particle packaged cDNA for HOMER1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for HOMER1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for HOMER1 gene
- Search ViGene Biosciences for HOMER1
- Santa Cruz Biotechnology (SCBT) Antibodies for HOMER1
- Search Santa Cruz Biotechnology (SCBT) for HOMER1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for HOMER1
- Horizon Cell Lines for HOMER1
- Cyagen custom Knockout/knockin (KOKI) mouse models for HOMER1
- VectorBuilder custom plasmid, inducible vectors for HOMER1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HOMER1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for HOMER1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
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