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Aliases for HNRNPUL2 Gene

Aliases for HNRNPUL2 Gene

  • Heterogeneous Nuclear Ribonucleoprotein U Like 2 2 3
  • Heterogeneous Nuclear Ribonucleoprotein U-Like 2 2 5
  • Scaffold-Attachment Factor A2 3 4
  • HNRPUL2 3 4
  • SAF-A2 3 4
  • Heterogeneous Nuclear Ribonucleoprotein U-Like Protein 2 3

External Ids for HNRNPUL2 Gene

Previous HGNC Symbols for HNRNPUL2 Gene


Previous GeneCards Identifiers for HNRNPUL2 Gene

  • GC11M062236
  • GC11M062482
  • GC11M058810
  • GC11M062493

Summaries for HNRNPUL2 Gene

GeneCards Summary for HNRNPUL2 Gene

HNRNPUL2 (Heterogeneous Nuclear Ribonucleoprotein U Like 2) is a Protein Coding gene. GO annotations related to this gene include poly(A) RNA binding and kinase activity. An important paralog of this gene is HNRNPUL2-BSCL2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HNRNPUL2 Gene

Genomics for HNRNPUL2 Gene

Regulatory Elements for HNRNPUL2 Gene

Enhancers for HNRNPUL2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around HNRNPUL2 on UCSC Golden Path with GeneCards custom track

Promoters for HNRNPUL2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for HNRNPUL2 Gene

62,712,625 bp from pter
62,727,385 bp from pter
14,761 bases
Minus strand

Genomic View for HNRNPUL2 Gene

Genes around HNRNPUL2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HNRNPUL2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HNRNPUL2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HNRNPUL2 Gene

Proteins for HNRNPUL2 Gene

  • Protein details for HNRNPUL2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Heterogeneous nuclear ribonucleoprotein U-like protein 2
    Protein Accession:
    Secondary Accessions:
    • Q8N3B3

    Protein attributes for HNRNPUL2 Gene

    747 amino acids
    Molecular mass:
    85105 Da
    Quaternary structure:
    • Binds to MLF1 and retains it in the nucleus.

neXtProt entry for HNRNPUL2 Gene

Post-translational modifications for HNRNPUL2 Gene

  • Ubiquitination at Lys 273, Lys 406, Lys 471, Lys 553, and Lys 601
  • Modification sites at PhosphoSitePlus

Other Protein References for HNRNPUL2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for HNRNPUL2 Gene

Domains & Families for HNRNPUL2 Gene

Protein Domains for HNRNPUL2 Gene

Suggested Antigen Peptide Sequences for HNRNPUL2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 B30.2/SPRY domain.
  • Contains 1 B30.2/SPRY domain.
  • Contains 1 SAP domain.
genes like me logo Genes that share domains with HNRNPUL2: view

No data available for Gene Families for HNRNPUL2 Gene

Function for HNRNPUL2 Gene

Gene Ontology (GO) - Molecular Function for HNRNPUL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with HNRNPUL2: view

Phenotypes for HNRNPUL2 Gene

genes like me logo Genes that share phenotypes with HNRNPUL2: view

Animal Model Products

CRISPR Products

miRNA for HNRNPUL2 Gene

miRTarBase miRNAs that target HNRNPUL2

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for HNRNPUL2 Gene

Localization for HNRNPUL2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for HNRNPUL2 Gene

Subcellular locations from

Jensen Localization Image for HNRNPUL2 Gene COMPARTMENTS Subcellular localization image for HNRNPUL2 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for HNRNPUL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus ISS --
GO:0005654 nucleoplasm IDA --
GO:0016020 membrane IDA 19946888
genes like me logo Genes that share ontologies with HNRNPUL2: view

Pathways & Interactions for HNRNPUL2 Gene

SuperPathways for HNRNPUL2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for HNRNPUL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with HNRNPUL2: view

No data available for Pathways by source and SIGNOR curated interactions for HNRNPUL2 Gene

Drugs & Compounds for HNRNPUL2 Gene

No Compound Related Data Available

Transcripts for HNRNPUL2 Gene


(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(779) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HNRNPUL2 Gene

Heterogeneous nuclear ribonucleoprotein U-like 2:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for HNRNPUL2 Gene

No ASD Table

Relevant External Links for HNRNPUL2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for HNRNPUL2 Gene

mRNA expression in normal human tissues for HNRNPUL2 Gene

Protein differential expression in normal tissues from HIPED for HNRNPUL2 Gene

This gene is overexpressed in Tlymphocyte (9.9), Peripheral blood mononuclear cells (7.1), and Lymph node (6.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for HNRNPUL2 Gene

Protein tissue co-expression partners for HNRNPUL2 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of HNRNPUL2 Gene:


SOURCE GeneReport for Unigene cluster for HNRNPUL2 Gene:

genes like me logo Genes that share expression patterns with HNRNPUL2: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for HNRNPUL2 Gene

Orthologs for HNRNPUL2 Gene

This gene was present in the common ancestor of animals.

Orthologs for HNRNPUL2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia HNRNPUL2 34
  • 94.33 (n)
  • 96.79 (a)
  • 96 (a)
(Canis familiaris)
Mammalia HNRNPUL2 34
  • 94.96 (n)
  • 97.59 (a)
-- 35
  • 96 (a)
(Mus musculus)
Mammalia Hnrnpul2 34
  • 92.13 (n)
  • 95.17 (a)
Hnrnpul2 16
Hnrnpul2 35
  • 95 (a)
(Pan troglodytes)
Mammalia HNRNPUL2 34
  • 99.64 (n)
  • 99.46 (a)
  • 99 (a)
(Rattus norvegicus)
Mammalia Hnrnpul2 34
  • 92.26 (n)
  • 95.17 (a)
(Monodelphis domestica)
Mammalia -- 35
  • 82 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 80 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 60 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia hnrnpul2 34
  • 61.47 (n)
  • 54.58 (a)
Str.17711 34
African clawed frog
(Xenopus laevis)
Amphibia Xl.11697 34
(Danio rerio)
Actinopterygii HNRNPUL2 35
  • 35 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG30122 35
  • 17 (a)
(Caenorhabditis elegans)
Secernentea Y41E3.11 35
  • 8 (a)
Species where no ortholog for HNRNPUL2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for HNRNPUL2 Gene

Gene Tree for HNRNPUL2 (if available)
Gene Tree for HNRNPUL2 (if available)

Paralogs for HNRNPUL2 Gene

Paralogs for HNRNPUL2 Gene

(4) SIMAP similar genes for HNRNPUL2 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with HNRNPUL2: view

Variants for HNRNPUL2 Gene

Structural Variations from Database of Genomic Variants (DGV) for HNRNPUL2 Gene

Variant ID Type Subtype PubMed ID
nsv348 CNV deletion 18451855
nsv555174 CNV gain 21841781

Variation tolerance for HNRNPUL2 Gene

Residual Variation Intolerance Score: 23% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.78; 47.28% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for HNRNPUL2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for HNRNPUL2 Gene

Disorders for HNRNPUL2 Gene

Relevant External Links for HNRNPUL2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for HNRNPUL2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HNRNPUL2 Gene

Publications for HNRNPUL2 Gene

  1. Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. (PMID: 25609649) Li X. … Chen J. (Mol. Syst. Biol. 2015) 3 65
  2. BioID-based Identification of Skp Cullin F-box (SCF)I^-TrCP1/2 E3 Ligase Substrates. (PMID: 25900982) Coyaud E. … Raught B. (Mol. Cell Proteomics 2015) 3 65
  3. Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation. (PMID: 25921289) Emdal K.B. … Olsen J.V. (Sci Signal 2015) 3 65
  4. Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage. (PMID: 25963833) Drissi R. … Boisvert F.M. (Mol. Cell Proteomics 2015) 3 65
  5. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 65

Products for HNRNPUL2 Gene

Sources for HNRNPUL2 Gene

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