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Aliases for HNRNPUL2 Gene

Aliases for HNRNPUL2 Gene

  • Heterogeneous Nuclear Ribonucleoprotein U-Like 2 2 3
  • Scaffold-Attachment Factor A2 3 4
  • HNRPUL2 3 4
  • SAF-A2 3 4
  • Heterogeneous Nuclear Ribonucleoprotein U-Like Protein 2 3

External Ids for HNRNPUL2 Gene

Previous HGNC Symbols for HNRNPUL2 Gene

  • HNRPUL2

Previous GeneCards Identifiers for HNRNPUL2 Gene

  • GC11M062236
  • GC11M062482
  • GC11M058810
  • GC11M062493

Summaries for HNRNPUL2 Gene

GeneCards Summary for HNRNPUL2 Gene

HNRNPUL2 (Heterogeneous Nuclear Ribonucleoprotein U-Like 2) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is HNRNPUL2-BSCL2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HNRNPUL2 Gene

Genomics for HNRNPUL2 Gene

Regulatory Elements for HNRNPUL2 Gene

Genomic Location for HNRNPUL2 Gene

Start:
62,712,625 bp from pter
End:
62,727,385 bp from pter
Size:
14,761 bases
Orientation:
Minus strand

Genomic View for HNRNPUL2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for HNRNPUL2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HNRNPUL2 Gene

Proteins for HNRNPUL2 Gene

  • Protein details for HNRNPUL2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q1KMD3-HNRL2_HUMAN
    Recommended name:
    Heterogeneous nuclear ribonucleoprotein U-like protein 2
    Protein Accession:
    Q1KMD3
    Secondary Accessions:
    • Q8N3B3

    Protein attributes for HNRNPUL2 Gene

    Size:
    747 amino acids
    Molecular mass:
    85105 Da
    Quaternary structure:
    • Binds to MLF1 and retains it in the nucleus.

neXtProt entry for HNRNPUL2 Gene

Proteomics data for HNRNPUL2 Gene at MOPED

Post-translational modifications for HNRNPUL2 Gene

  • Ubiquitination at Lys273, Lys406, Lys471, Lys553, and Lys601
  • Modification sites at PhosphoSitePlus

Other Protein References for HNRNPUL2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for HNRNPUL2 Gene

Domains for HNRNPUL2 Gene

Protein Domains for HNRNPUL2 Gene

Suggested Antigen Peptide Sequences for HNRNPUL2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q1KMD3

UniProtKB/Swiss-Prot:

HNRL2_HUMAN :
  • Q1KMD3
Domain:
  • Contains 1 B30.2/SPRY domain.
  • Contains 1 SAP domain.
genes like me logo Genes that share domains with HNRNPUL2: view

No data available for Gene Families for HNRNPUL2 Gene

Function for HNRNPUL2 Gene

Gene Ontology (GO) - Molecular Function for HNRNPUL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
GO:0005524 ATP binding --
GO:0016301 kinase activity --
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with HNRNPUL2: view

Animal Model Products

CRISPR Products

miRNA for HNRNPUL2 Gene

miRTarBase miRNAs that target HNRNPUL2

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for HNRNPUL2

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for HNRNPUL2 Gene

Localization for HNRNPUL2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for HNRNPUL2 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for HNRNPUL2 Gene COMPARTMENTS Subcellular localization image for HNRNPUL2 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for HNRNPUL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus ISS --
GO:0016020 membrane IDA 19946888
genes like me logo Genes that share ontologies with HNRNPUL2: view

Pathways for HNRNPUL2 Gene

SuperPathways for HNRNPUL2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for HNRNPUL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with HNRNPUL2: view

No data available for Pathways by source for HNRNPUL2 Gene

Transcripts for HNRNPUL2 Gene

mRNA/cDNA for HNRNPUL2 Gene

(779) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HNRNPUL2 Gene

Heterogeneous nuclear ribonucleoprotein U-like 2:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for HNRNPUL2

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for HNRNPUL2
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for HNRNPUL2 Gene

No ASD Table

Relevant External Links for HNRNPUL2 Gene

GeneLoc Exon Structure for
HNRNPUL2
ECgene alternative splicing isoforms for
HNRNPUL2

Expression for HNRNPUL2 Gene

mRNA expression in normal human tissues for HNRNPUL2 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for HNRNPUL2 Gene

SOURCE GeneReport for Unigene cluster for HNRNPUL2 Gene Hs.657058

genes like me logo Genes that share expressions with HNRNPUL2: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for HNRNPUL2 Gene

Orthologs for HNRNPUL2 Gene

This gene was present in the common ancestor of animals.

Orthologs for HNRNPUL2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia HNRNPUL2 35
  • 99.64 (n)
  • 99.46 (a)
HNRNPUL2 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia HNRNPUL2 35
  • 94.33 (n)
  • 96.79 (a)
HNRNPUL2 36
  • 96 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 96 (a)
OneToMany
HNRNPUL2 35
  • 94.96 (n)
  • 97.59 (a)
mouse
(Mus musculus)
Mammalia Hnrnpul2 35
  • 92.13 (n)
  • 95.17 (a)
Hnrnpul2 16
Hnrnpul2 36
  • 95 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 82 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 80 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Hnrnpul2 35
  • 92.26 (n)
  • 95.17 (a)
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 60 (a)
OneToMany
African clawed frog
(Xenopus laevis)
Amphibia Xl.11697 35
tropical clawed frog
(Silurana tropicalis)
Amphibia hnrnpul2 35
  • 61.47 (n)
  • 54.58 (a)
Str.17711 35
zebrafish
(Danio rerio)
Actinopterygii HNRNPUL2 36
  • 35 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG30122 36
  • 17 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea Y41E3.11 36
  • 8 (a)
OneToMany
Species with no ortholog for HNRNPUL2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for HNRNPUL2 Gene

ENSEMBL:
Gene Tree for HNRNPUL2 (if available)
TreeFam:
Gene Tree for HNRNPUL2 (if available)

Paralogs for HNRNPUL2 Gene

Paralogs for HNRNPUL2 Gene

Selected SIMAP similar genes for HNRNPUL2 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with HNRNPUL2: view

Variants for HNRNPUL2 Gene

Structural Variations from Database of Genomic Variants (DGV) for HNRNPUL2 Gene

Variant ID Type Subtype PubMed ID
nsv897623 CNV Loss 21882294
nsv348 CNV Loss 18451855

Relevant External Links for HNRNPUL2 Gene

HapMap Linkage Disequilibrium report
HNRNPUL2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for HNRNPUL2 Gene

Disorders for HNRNPUL2 Gene

No disorders were found for HNRNPUL2 Gene.

No data available for UniProtKB/Swiss-Prot for HNRNPUL2 Gene

Publications for HNRNPUL2 Gene

  1. Purification of two isoforms of hnRNP-U and characterization of their nucleic acid binding activity. (PMID: 8068679) Fackelmayer F.O. … Richter A. (Biochemistry 1994) 3
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PMID: 16964243) Beausoleil S.A. … Gygi S.P. (Nat. Biotechnol. 2006) 3
  5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3

Products for HNRNPUL2 Gene

  • antibodies-online proteins for HNRNPUL2
  • antibodies-online antibodies for HNRNPUL2
  • antibodies-online kits for HNRNPUL2

Sources for HNRNPUL2 Gene

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