Aliases for HNRNPLL Gene
External Ids for HNRNPLL Gene
Previous HGNC Symbols for HNRNPLL Gene
Previous GeneCards Identifiers for HNRNPLL Gene
HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).[supplied by OMIM, Aug 2008]
GeneCards Summary for HNRNPLL Gene
HNRNPLL (Heterogeneous Nuclear Ribonucleoprotein L Like) is a Protein Coding gene. Diseases associated with HNRNPLL include t cell deficiency and congenital myasthenic syndrome. GO annotations related to this gene include nucleic acid binding and RNA binding. An important paralog of this gene is ENSG00000268083.
UniProtKB/Swiss-Prot for HNRNPLL Gene
RNA-binding protein that functions as regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC.