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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HNRNPH2 Gene

protein-coding   GIFtS: 50
GCID: GC0XP100663

Heterogeneous Nuclear Ribonucleoprotein H2 (H')


(Previous symbol: HNRPH2)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Heterogeneous Nuclear Ribonucleoprotein H2 (H')1 2     HNRPH'2
HNRPH21 2 3 5     Heterogeneous Nuclear Ribonucleoprotein H-Prime2
FTP-32 3     Heterogeneous Nuclear Ribonucleoprotein H22
FTP32 3     hnRNPH'2
HnRNP H'2 3     Heterogeneous Nuclear Ribonucleoprotein H'3
HnRNP H22 3     

External Ids:    HGNC: 50421   Entrez Gene: 31882   Ensembl: ENSG000001269457   OMIM: 3006105   UniProtKB: P557953   

Export aliases for HNRNPH2 gene to outside databases

Previous GC identifers: GC0XP100549 GC0XP100533 GC0XP090469


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for HNRNPH2 Gene:
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs).
The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are
associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA
metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the
nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded
by this gene has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member
HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype.
Alternative splicing results in multiple transcript variants encoding the same protein. Read-through
transcription between this locus and the ribosomal protein L36a gene has been observed. (provided by RefSeq, Jan
2011)

GeneCards Summary for HNRNPH2 Gene: 
HNRNPH2 (heterogeneous nuclear ribonucleoprotein H2 (H')) is a protein-coding gene. Diseases associated with HNRNPH2 include agammaglobulinemia, and down syndrome, and among its related super-pathways are mRNA Processing and Generic Transcription Pathway. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is HNRNPH3.

UniProtKB/Swiss-Prot: HNRH2_HUMAN, P55795
Function: This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which
provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable
mRNAs in the cytoplasm. Binds poly(RG)

Gene Wiki entry for HNRNPH2 (HNRPH2) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HNRNPH2 gene promoter:
         HOXA9B   HOXA9   C/EBPbeta   p53   GATA-2   CREB   IRF-2   deltaCREB   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHNRNPH2 promoter sequence
   Search SABiosciences Chromatin IP Primers for HNRNPH2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HNRNPH2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq22   Ensembl cytogenetic band:  Xq22.1   HGNC cytogenetic band: Xq22

HNRNPH2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HNRNPH2 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP100663:  view genomic region     (about GC identifiers)

Start:
100,663,121 bp from pter      End:
100,669,128 bp from pter
Size:
6,008 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: HNRH2_HUMAN, P55795 (See protein sequence)
Recommended Name: Heterogeneous nuclear ribonucleoprotein H2  
Size: 449 amino acids; 49264 Da
Subunit: Interacts with TXNL4/DIM1
Subcellular location: Nucleus, nucleoplasm
2 PDB 3D structures from and Proteopedia for HNRNPH2:
1WEZ (3D)        1WG5 (3D)    
Secondary accessions: A1L400 Q9HHA7

Explore the universe of human proteins at neXtProt for HNRNPH2: NX_P55795

Explore proteomics data for HNRNPH2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P55795

  • HNRNPH2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    HNRNPH2 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001027565.1  NP_062543.1  

    ENSEMBL proteins: 
     ENSP00000361927  
    Reactome Protein details: P55795
    Human Recombinant Protein Products for HNRNPH2: 
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    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005654nucleoplasm TAS--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0015629actin cytoskeleton IDA--

    HNRNPH2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    RBM: RNA binding motif (RRM) containing

    3 InterPro protein domains:
     IPR012996 Znf_CHHC
     IPR012677 Nucleotide-bd_a/b_plait
     IPR000504 RRM_dom

    Graphical View of Domain Structure for InterPro Entry P55795

    ProtoNet protein and cluster: P55795

    2 Blocks protein domains:
    IPB000504 RNA-binding region RNP-1 (RNA recognition motif)
    IPB012996 Zinc finger


    UniProtKB/Swiss-Prot: HNRH2_HUMAN, P55795
    Similarity: Contains 3 RRM (RNA recognition motif) domains


    HNRNPH2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HNRH2_HUMAN, P55795
    Function: This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which
    provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable
    mRNAs in the cytoplasm. Binds poly(RG)

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding IEA--
         
    HNRNPH2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for HNRNPH2 
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    8/28 QIAGEN miScript miRNA Assays for microRNAs that regulate HNRNPH2 (see all 28):
    hsa-miR-495 hsa-miR-4307 hsa-miR-4328 hsa-miR-300 hsa-miR-429 hsa-miR-485-3p hsa-miR-624 hsa-miR-513c
    SwitchGear 3'UTR luciferase reporter plasmidHNRNPH2 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for HNRNPH2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1mRNA Splicing - Major Pathway
    Processing of Capped Intron-Containing Pre-mRNA0.85
    mRNA Splicing0.82
    mRNA Processing0.85
    mRNA processing0.46
    mRNA Splicing - Major Pathway0.82
    2Generic Transcription Pathway
    Gene Expression0.47

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for HNRNPH2
        mRNA processing

    5        Reactome Pathways for HNRNPH2
        mRNA Splicing - Major Pathway
    mRNA Splicing
    Gene Expression
    mRNA Processing
    Processing of Capped Intron-Containing Pre-mRNA



    HNRNPH2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HNRNPH2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/153 Interacting proteins for HNRNPH2 (P557952, 3 ENSP000003619274) via UniProtKB, MINT, STRING, and/or I2D (see all 153)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    YWHAZP631042, 3, ENSP000003095034MINT-3296856 I2D: score=1 STRING: ENSP00000309503
    ESR2Q927313, ENSP000003439254I2D: score=1 STRING: ENSP00000343925
    GPN1Q9HCN43, ENSP000002647184I2D: score=1 STRING: ENSP00000264718
    MEPCEQ7L2J03, ENSP000003085464I2D: score=1 STRING: ENSP00000308546
    TOB1P506163, ENSP000002689574I2D: score=1 STRING: ENSP00000268957
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000398mRNA splicing, via spliceosome TAS--
    GO:0008380RNA splicing TAS--
    GO:0010467gene expression TAS--

    HNRNPH2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HNRNPH2 (HNRH2)

    Search CenterWatch for drugs/clinical trials and news about HNRNPH2 / HNRH2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for HNRNPH2 gene (2 alternative transcripts): 
    NM_001032393.2  NM_019597.4  

    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000316594(uc022cag.1 uc022cah.1 uc004ehm.3 uc004ehn.3)

    miRNA
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    hsa-miR-495 hsa-miR-4307 hsa-miR-4328 hsa-miR-300 hsa-miR-429 hsa-miR-485-3p hsa-miR-624 hsa-miR-513c
    SwitchGear 3'UTR luciferase reporter plasmidHNRNPH2 3' UTR sequence
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    24/398 AceView cDNA sequences (see all 398):

    BM711429 BM836238 CA433879 H08425 BU171922 BU154901 CR624721 BG577424 
    BM699715 AI168039 AI799921 AA854281 AA025725 BP341852 BE502957 BU172557 
    U01923 AU132183 BQ050496 CB134552 BP340853 BU622622 CF127855 BQ214181 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for HNRNPH2    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c
    SP1:                                                
    SP2:                                                
    SP3:                    -                           
    SP4:                                                


    ECgene alternative splicing isoforms for HNRNPH2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HNRNPH2 expression in normal human tissues (normalized intensities)      HNRNPH2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    HNRNPH2 Expression
    About this image


    HNRNPH2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/35 selected tissues (see all 35) fully expand
     
     Epithelium
             vagina ; squamous epithelial cells   
     
     Uterus
             uterus, post-menopause ; glandular cells   
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 4 entries
             colon ; peripheral nerve/ganglion   
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex

    See HNRNPH2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HNRNPH2

    UniProtKB/Swiss-Prot: HNRH2_HUMAN, P55795
    Tissue specificity: Expressed ubiquitously

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for HNRNPH2 gene from 4/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hnrnph21 , 5 heterogeneous nuclear ribonucleoprotein H21, 5 93.69(n)1
    99.11(a)1
      X (56.20 cM)5
    562581  NM_019868.31  NP_063921.11 
     1346011795 
    chicken
    (Gallus gallus)
    Aves HNRNPH16
    heterogeneous nuclear ribonucleoprotein H
    72(a)
    1 → many
    13(12896978-12911863)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    82(a)
    1 → many
    2(140417161-140425189)
    zebrafish
    (Danio rerio)
    Actinopterygii hnrnph16
    hnrnph1l6
    heterogeneous nuclear ribonucleoprotein H1, like
    78(a)
    77(a)
    many ↔ many
    many ↔ many
    14(6957524-6980892)
    21(28913671-28925825)


    ENSEMBL Gene Tree for HNRNPH2 (if available)
    TreeFam Gene Tree for HNRNPH2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HNRNPH2 gene
    HNRNPH32  RBM12B2  ESRP12  GRSF12  ESRP22  HNRNPH12  HNRNPF2  RBM122  
    5 SIMAP similar genes for HNRNPH2 using alignment to 1 protein entry:     HNRH2_HUMAN:
    DKFZp686A15170    HNRNPH1    HNRNPF    HNRNPH3    GRSF1

    HNRNPH2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    7 SNPs in HNRNPH2 are shown    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1453111181,2
    F--100635043(+) AGATAT/CGTGGA 4 /Y syn11Minor allele frequency- C:0.00NA 4542
    rs31902551,2
    C--100635080(+) CAAGTG/TGGGGT 4 G W mis12Minor allele frequency- T:0.00MN NA 186
    rs1997731771,2
    --100635146(+) GTGGCA/GCTTAT 4 T A mis10--------
    rs1476633581,2
    C--100635163(+) CAAATG/CATGGG 4 /I /M mis11Minor allele frequency- C:0.00NA 4550
    rs3728235861,2
    ----100635193(+) CAGTCC/TAGTTA 4 S syn10--------
    rs3747303211,2
    ----100634959(+) GTTACC/TGGTGA 4 T syn10--------
    rs3690568491,2
    ----100635143(+) GTGGTA/GGCGCT 4 S G mis10--------

    HapMap Linkage Disequilibrium report for HNRNPH2 (100663121 - 100669128 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for HNRNPH2: --

    Locus Specific Mutation Databases (LSDB): HNRNPH2
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 300610    OMIM disorders: --

    2 diseases for HNRNPH2:    About MalaCards
    agammaglobulinemia    down syndrome


    HNRNPH2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): HNRNPH2
    Human Genome Epidemiology (HuGE) Navigator: HNRNPH2 (3 documents)

    Export disorders for HNRNPH2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HNRNPH2 gene, integrated from 9 sources (see all 63):
    (articles sorted by number of sources associating them with HNRNPH2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Heterogeneous nuclear ribonucleoproteins H, H', and F are members of a ubiquitously expressed subfamily of related but distinct proteins encoded by genes mapping to different chromosomes. (PubMed id 7499401)1, 2, 3 Honore B.... Celis J.E. (1995)
    2. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    3. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
    4. Evidence that Dim1 associates with proteins involved in pre-mRNA splicing, and delineation of residues essential for Dim1 interactions with hnRNP F and Npw38/PQBP-1. (PubMed id 11054566)1, 2 Zhang Y.-Z....Golemis E.A. (2000)
    5. Large-scale comparative sequence analysis of the human and murine Bruton's tyrosine kinase loci reveals conserved regulatory domains. (PubMed id 9110171)1, 2 Oeltjen J.C....Belmont J.W. (1997)
    6. Isolation of cosmid and cDNA clones in the region surrounding the BTK gene at Xq21.3-q22. (PubMed id 7959728)1, 2 Vorechovsky I.... Ochs H.D. (1994)
    7. VCP phosphorylation-dependent interaction partners pre vent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (2013)
    8. Deubiquitinase FAM/USP9X interacts with the E3 ubiquit in ligase SMURF1 protein and protects it from ligase activity-dependent self-deg radation. (PubMed id 23184937)1 Xie Y....Cong F. (2013)
    9. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (2013)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 3188 HGNC: 5042 AceView: HNRPH2 Ensembl:ENSG00000126945 euGenes: HUgn3188
    ECgene: HNRNPH2 H-InvDB: HNRNPH2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HNRNPH2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for HNRNPH2 gene:
    Search GeneIP for patents involving HNRNPH2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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