HNRNPH1 Gene
protein-coding GIFtS: 52
GCID: GC05M179043
|
|
heterogeneous nuclear ribonucleoprotein H1 (H)
(Previous symbol: HNRPH1)
| |
Aliases
for HNRNPH1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Heterogeneous Nuclear Ribonucleoprotein H1 (H)1 2 | | HNRPH11 2 3 5 | | HnRNPH1 | | HNRPH2 3 | | Heterogeneous Nuclear Ribonucleoprotein H2 | | HnRNP H3 |
Export aliases for HNRNPH1 gene to outside databasesPrevious GC identifers: GC05M178974 GC05M173768 |
Summaries
for HNRNPH1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for HNRNPH1:
This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs).The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated withpre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism andtransport. While all of the hnRNPs are present in the nucleus, some may shuttle between the nucleus and the cytoplasm.The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeatsof quasi-RRM domains that bind to RNA and is very similar to the family member HNRPF. This gene may be associated withhereditary lymphedema type I. Alternatively spliced transcript variants have been described (provided by RefSeq, Mar2012)
UniProtKB/Swiss-Prot: HNRH1_HUMAN, P31943Function: This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which providethe substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in thecytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR)pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG)
Gene Wiki entry for HNRNPH1 (HNRPH1)
|
Genomic Views
for HNRNPH1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_023133.13
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the HNRNPH1 gene promoter:
TBP STAT1 Sox5 STAT1beta IRF-1 Nkx2-5 STAT1alpha FOXO4 TFIID STAT2
Other transcription factors
Search SABiosciences Chromatin IP Primers for HNRNPH1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HNRNPH1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q35.3 Ensembl cytogenetic band: 5q35.3 HGNC cytogenetic band: 5q35.3HNRNPH1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05M179043: view genomic region
(about GC identifiers)
Start:
|
179,041,179 bp from pter |
End:
|
179,061,785 bp from pter |
Size:
|
20,607 bases |
Orientation:
|
minus strand |
|
Proteins
for HNRNPH1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: HNRH1_HUMAN, P31943 (See
protein sequence)Recommended Name: Heterogeneous nuclear ribonucleoprotein H Size: 449 amino acids; 49229 Da
Subunit: Part of a ternary complex containing FUBP2, PTBP1, PTBP2 and HNRNPH1. Identified in the spliceosome C complex.Interacts with IGF2BP1. Interacts with CUGBP1; the interaction is RNA-dependent. Interacts with MBNL1; the interactionin RNA-independent
Subcellular location: Nucleus, nucleoplasm
1 PDB 3D structure from  and Proteopedia  for HNRNPH1:2LXU (3D)
Secondary accessions: B3KW86 D3DWQ2 Q6IBM4Explore the universe of human proteins at neXtProt for HNRNPH1: NX_P31943
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P31943
HNRNPH1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001244222.1 NP_005511.1
ENSEMBL proteins: ENSP00000377082 ENSP00000397797 ENSP00000349168 ENSP00000327539 ENSP00000425851 ENSP00000426275 ENSP00000429673 ENSP00000429481 ENSP00000427845 ENSP00000430445 ENSP00000428620 ENSP00000429270 ENSP00000427408 ENSP00000422955 ENSP00000425732 ENSP00000420850 ENSP00000427986 ENSP00000424087 ENSP00000423140 ENSP00000430970 ENSP00000430156 ENSP00000427388 ENSP00000426518 ENSP00000421695 ENSP00000429661 ENSP00000425343 ENSP00000427351 ENSP00000426726 ENSP00000429179 ENSP00000444220 Reactome Protein details: P31943
Human Recombinant Protein Products:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
HNRNPH1 for ontologies About GeneDecksing
HNRNPH1 Antibody Products:
Assay Products for HNRNPH1: |
Protein
Domains /
Families
for HNRNPH1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
HNRNPH1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P31943ProtoNet protein and cluster: P31943 2 Blocks protein families: IPB000504 RNA-binding region RNP-1 (RNA recognition motif) IPB012996 Zinc finger
UniProtKB/Swiss-Prot: HNRH1_HUMAN, P31943Domain: Each quasi-RRM repeat bound poly(RG), while only the N-terminal QRRM bound poly(RC) and poly(RU). None of therepeats bound detectable amounts of poly(RA)Similarity: Contains 3 RRM (RNA recognition motif) domains |
Function
for HNRNPH1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: HNRH1_HUMAN, P31943Function: This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which providethe substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in thecytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR)pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG)Induction: Up-regulated in myotonic dystrophy pathophysiology (DM)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HNRNPH1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HNRNPH1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: HNRNPH1 (NM_005520) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HNRNPH1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HNRNPH1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HNRNPH1 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
HNRNPH1 for ontologies About GeneDecksing
5 GenomeRNAi human phenotypes for HNRNPH1:
|
Pathways & Interactions
for HNRNPH1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | mRNA Splicing - Major Pathway | | | 2 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for HNRNPH1
5 
Reactome Pathways for HNRNPH1
HNRNPH1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HNRNPH1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/852 Interacting proteins for HNRNPH1 (P319432, 3 ENSP000003491684) via UniProtKB, MINT, STRING, and/or I2D (see all 852)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| SMN1 | Q166372, 3, ENSP000003700834 | MINT-7945693 MINT-7947479 I2D:
score=2 STRING: ENSP00000370083 | | SMN2 | Q166372, 3, ENSP000003701194 | MINT-7945693 MINT-7947479 I2D:
score=2 STRING: ENSP00000370119 | | DDX5 | P178442, 3, ENSP000002257924 | MINT-7945693 MINT-7947479 MINT-8338487 I2D:
score=1 STRING: ENSP00000225792 | | ACTB | P607092, 3, ENSP000003499604 | MINT-7945693 MINT-7947479 I2D:
score=1 STRING: ENSP00000349960 | | CCT4 | P509912, 3, ENSP000003779584 | MINT-7945693 MINT-7947479 I2D:
score=1 STRING: ENSP00000377958 |
About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
HNRNPH1 for ontologies About GeneDecksing
|
Drugs & Compounds
for HNRNPH1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for HNRNPH1
Search CenterWatch for drugs/clinical trials and news about HNRNPH1 / HNRH1
|
Transcripts
for HNRNPH1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for HNRNPH1 gene (2 alternative transcripts): NM_001257293.1 NM_005520.2 Unigene Cluster for HNRNPH1: Heterogeneous nuclear ribonucleoprotein H1 (H) Hs.604001 [show with all ESTs]Unigene Representative Sequence: BX64720518/50 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 50): ENST00000393432(uc021yjd.1 uc003mkf.4) ENST00000502904(uc011dgn.2)
ENST00000442819(uc003mke.4) ENST00000356731(uc003mkh.4) ENST00000515481
ENST00000514332(uc003mkg.4) ENST00000329433 ENST00000510678 ENST00000510411
ENST00000523449 ENST00000524179 ENST00000519033 ENST00000521720 ENST00000502632
ENST00000519958 ENST00000523136 ENST00000504549 ENST00000514731
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HNRNPH1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HNRNPH1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: HNRNPH1 (NM_005520) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HNRNPH1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HNRNPH1 |
Additional cDNA sequence: AK092273.1 AK124530.1 AK298193.1 AK307693.1 AK311021.1 BC001348.2 BX647205.1 CR456778.1 CR749414.1 L22009.1 24/63 DOTS entries (see all 63): DT.91697189 DT.100881107 DT.100881105 DT.97805805 DT.92019775 DT.97788560 DT.120820453 DT.120820494 DT.120820460 DT.100649872 DT.97860617 DT.91762692 DT.95291383 DT.95276837 DT.99960760 DT.40133283 DT.100881111 DT.91762691 DT.449894 DT.87006909 DT.100881112 DT.120820510 DT.91712573 DT.91762690 24/775 AceView cDNA sequences (see all 775): BE906339 T50307 BQ771671 AI696040 AW375858 AL699721 AA471161 BE676482 AA811583 H88532 BG680125 AI579958 BU729168 BU600976 W61325 AW246596 AA972385 BE294876 AA731437 AA910447 BQ028714 AI651020 AA928529 AI915188
GeneLoc Exon Structure
5/28 Alternative Splicing Database (ASD) splice patterns (SP) for HNRNPH1 (see all 28) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | · | 3c | · | 3d | · | 3e | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | · | 8d | ^ | 9a | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | - | | - | | - | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | - | | - | | - | | | | | | | | | | - | | - | | - | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | - | | - | | - | | | | | | | | | | - | | - | | - | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 9b | · | 9c | · | 9d | · | 9e | ^ | 10a | · | 10b | · | 10c | · | 10d | · | 10e | · | 10f | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b | · | 13c | · | 13d | ^ | 14a | · | 14b | ^ | 15a | · | 15b | ^ | 16a | · | 16b | · | 16c | ^ | 17 | ^ | 18a | · |
|---|
|
| SP1: | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | - | | | | | | | | | | - | | | | | | - | | - | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | - | | | | | | - | | - | | | | | | | | |
| SP4: | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | | | | | | |
ECgene alternative splicing isoforms for HNRNPH1
|
Expression
for HNRNPH1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| HNRNPH1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See HNRNPH1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for HNRNPH1
SOURCE GeneReport for Unigene cluster: Hs.604001
UniProtKB/Swiss-Prot: HNRH1_HUMAN, P31943Tissue specificity: Expressed ubiquitously
SABiosciences Custom PCR Arrays for HNRNPH1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HNRNPH1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat HNRNPH1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HNRNPH1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HNRNPH1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HNRNPH1 |
Orthologs
for HNRNPH1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for HNRNPH1 gene from 9/24 species (see all 24) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Hnrnph11 , 5 |
heterogeneous nuclear ribonucleoprotein H11, 5 |
96.44(n)1
99.78(a)1 |
|
11 (30.56 cM)5
590131 NM_021510.21 NP_067485.11
503769905 |
chicken
(Gallus gallus) |
Aves |
HNRNPH11 |
heterogeneous nuclear ribonucleoprotein H1 (H) |
80.57(n)
86.62(a) |
|
395157 NM_204496.1 NP_989827.1 |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
77(a) |
1 → many |
2(140417148-140424568) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.226682 |
Xenopus laevis transcribed sequence with moderate similarity more |
79.94(n) |
|
BU913288.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.7822 |
Danio rerio mRNA similar to heterogeneous nuclear ribonucleoprotein more |
80.02(n) |
|
BC044161.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
glo1 |
glorund |
48.65(n)
39.38(a) |
|
41431 NM_169434.2 NP_731639.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
hrpf-21 |
Protein HRPF-2 |
48.98(n)
39.33(a) |
|
177398 NM_171360.2 NP_741422.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT3G208901 |
RNA-binding (RRM/RBD/RNP motifs) family protein |
47.98(n)
41.59(a) |
|
821638 NM_112981.3 NP_188725.3 |
rice
(Oryza sativa) |
Liliopsida |
---- |
RNA recognition motif containing protein, putative...RNA recognition motif containing protein, putative... |
31(a)30(a) |
many ↔ manymany ↔ many |
12(1496364-1498413) 11(1550980-1553325) |
ENSEMBL Gene Tree for HNRNPH1 (if available)
TreeFam Gene Tree for HNRNPH1 (if available) |
Paralogs
for HNRNPH1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for HNRNPH1 gene
- RBM12B2 HNRNPH32 HNRNPH22 ESRP12 GRSF12 HNRNPF2 ESRP22 RBM122
8 SIMAP similar genes for HNRNPH1 using alignment to 27 protein entries: HNRH1_HUMAN (see all proteins):DKFZp686A15170 HNRNPH2 HNRNPF OK/SW-cl.23 HNRNPH3 GRSF1
ESRP1 RBM12B
HNRNPH1 for paralogs About GeneDecksing
5 Pseudogenes.org Pseudogenes for HNRNPH1
PGOHUM00000244689 PGOHUM00000235226 PGOHUM00000257147 PGOHUM00000250191 PGOHUM00000241585
|
Genomic Variants
for HNRNPH1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for HNRNPH1 (179041179 - 179061785 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for HNRNPH1
2 CNVs: 93398 4481
2 Inversions: 0596 37259 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HNRNPH1 |
|
Disorders
/ Diseases
for HNRNPH1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
HNRNPH1 for disorders About GeneDecksing
OMIM gene information: 601035
OMIM disorders: --
15  diseases for HNRNPH1: About MalaCardshereditary lymphedema lymphedema myotonic dystrophy hepatitis c
endocarditis hepatocellular carcinoma colorectal cancer prostate cancer
myeloma hepatitis prostatitis thyroiditis
carcinoma neuronitis colorectal cancer 2
Export disorders for HNRNPH1 gene to outside databases
|
Publications
for HNRNPH1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
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PubMed articles for HNRNPH1 gene, integrated from 9 sources (see all 107):
(articles sorted by number of sources associating them with HNRNPH1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Heterogeneous nuclear ribonucleoproteins H, H', and F are members of a ubiquitously expressed subfamily of related but distinct proteins encoded by genes mapping to different chromosomes. (PubMed id 7499401)1, 2, 3, 9 Honore B.... Celis J.E. (1995)
- Molecular composition of IMP1 ribonucleoprotein granules. (PubMed id 17289661)1, 2 Joeson L.... Nielsen F.C. (2007)
- Interaction of muscleblind, CUG-BP1 and hnRNP H proteins in DM1-associated aberrant IR splicing. (PubMed id 16946708)1, 2 Paul S....Reddy S. (2006)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. (PubMed id 11991638)1, 2 Jurica M.S.... Moore M.J. (2002)
- Cooperative assembly of an hnRNP complex induced by a tissue-specific homolog of polypyrimidine tract binding protein. (PubMed id 11003644)1, 2 Markovtsov V....Black D.L. (2000)
- The hnRNP F protein: unique primary structure, nucleic acid-binding properties, and subcellular localization. (PubMed id 7512260)1, 2 Matunis M.J.... Dreyfuss G. (1994)
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External Searches for HNRNPH1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing HNRNPH1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing HNRNPH1 gene
(According to HUGE)
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Specialized Databases showing HNRNPH1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for HNRNPH1 | Pharmacogenomics, SNPs, Pathways |
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| Patent Information for HNRNPH1 gene:
Search GeneIP for patents involving HNRNPH1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for HNRNPH1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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