Aliases for HNRNPF Gene
Aliases for HNRNPF Gene
External Ids for HNRNPF Gene
- HGNC: 5039
- Entrez Gene: 3185
- Ensembl: ENSG00000169813
- OMIM: 601037
- UniProtKB: P52597
Previous HGNC Symbols for HNRNPF Gene
- HNRPF
Previous GeneCards Identifiers for HNRNPF Gene
- GC10M043202
- GC10M043881
- GC10M040407
Summaries for HNRNPF Gene
-
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for HNRNPF Gene
HNRNPF (Heterogeneous Nuclear Ribonucleoprotein F) is a Protein Coding gene. Among its related pathways are Gene Expression and Signaling by FGFR2. GO annotations related to this gene include nucleic acid binding and RNA binding. An important paralog of this gene is HNRNPH1.
UniProtKB/Swiss-Prot for HNRNPF Gene
-
Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HNRNPF Gene
Genomics for HNRNPF Gene
Regulatory Elements for HNRNPF Gene
Enhancers for HNRNPF Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around HNRNPF on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the HNRNPF gene promoter:
Regulatory Element Products
Genomic Location for HNRNPF Gene
- Chromosome:
- 10
- Start:
- 43,385,617 bp from pter
- End:
- 43,409,248 bp from pter
- Size:
- 23,632 bases
- Orientation:
- Minus strand
Genomic View for HNRNPF Gene
Genes around HNRNPF on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 10q11.21 by Ensembl
- 10q11.21 by Entrez Gene
- 10q11.21 by HGNC
HNRNPF Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HNRNPF Gene
Proteins for HNRNPF Gene
-
Protein details for HNRNPF Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P52597-HNRPF_HUMAN
- Recommended name:
- Heterogeneous nuclear ribonucleoprotein F
- Protein Accession:
- P52597
- B3KM84
- Q5T0N2
- Q96AU2
Protein attributes for HNRNPF Gene
- Size:
- 415 amino acids
- Molecular mass:
- 45672 Da
- Quaternary structure:
-
- Identified in the spliceosome C complex. Interacts with AGO1, AGO2, TBP and TXNL4/DIM1.
Protein Expression for HNRNPF Gene
Post-translational modifications for HNRNPF Gene
- Sumoylated.
- Ubiquitination at isoforms=87, posLast=167167, isoforms=200, isoforms=224, and isoforms=299
- Modification sites at PhosphoSitePlus
Other Protein References for HNRNPF Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for HNRNPF
-
Custom Antibody ServicesOriGene Antibodies for HNRNPF
- Novus Biologicals Antibodies for HNRNPF
-
Abcam antibodies for HNRNPF
- Invitrogen Antibodies for HNRNPF
- antibodies-online Antibodies for HNRNPF: See all 58
- GeneTex HNRNPF antibody for HNRNPF
-
Santa Cruz Biotechnology (SCBT) Antibodies for HNRNPF
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for HNRNPF
- Origene Custom Protein Services for HNRNPF
- antibodies-online Proteins for HNRNPF: See all 12
- Search antibodies-online for peptides
- Search GeneTex for Proteins for HNRNPF
Assay Products
- antibodies-online Kits for HNRNPF: See all 24
No data available for DME Specific Peptides for HNRNPF Gene
Domains & Families for HNRNPF Gene
Gene Families for HNRNPF Gene
Protein Domains for HNRNPF Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for HNRNPF Gene
Graphical View of Domain Structure for InterPro Entry
P52597UniProtKB/Swiss-Prot:
HNRPF_HUMAN :- The N-terminal RRM domains are responsible for recognizing the G-tract of BCL-X RNA.
- Domain:
-
- The N-terminal RRM domains are responsible for recognizing the G-tract of BCL-X RNA.
Function for HNRNPF Gene
Molecular function for HNRNPF Gene
- UniProtKB/Swiss-Prot Function:
- Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0003723 | RNA binding | IDA,TAS | 22658674 |
| GO:0003727 | single-stranded RNA binding | IDA | 20526337 |
| GO:0005515 | protein binding | IPI | 9111328 |
| GO:0008134 | transcription factor binding | IEA | -- |
Phenotypes for HNRNPF Gene
- GenomeRNAi human phenotypes for HNRNPF:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for HNRNPF gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HNRNPF gene
- Search ViGene Biosciences for HNRNPF
CRISPR Products
-
OriGene CRISPR knockouts for HNRNPF
-
Santa Cruz Biotechnology (SCBT) CRISPR for HNRNPF
- GenScript: Design CRISPR guide RNA sequences for HNRNPF
miRNA for HNRNPF Gene
- miRTarBase miRNAs that target HNRNPF
-
- hsa-mir-874-3p (MIRT037762)
- hsa-mir-615-3p (MIRT040073)
- hsa-mir-18a-3p (MIRT040847)
- hsa-mir-505-3p (MIRT041015)
- hsa-mir-339-5p (MIRT042766)
- hsa-mir-328-3p (MIRT043767)
- hsa-mir-27b-3p (MIRT046236)
- hsa-mir-10b-5p (MIRT047469)
- hsa-mir-10a-5p (MIRT047662)
- hsa-mir-92a-3p (MIRT049243)
- hsa-mir-16-5p (MIRT051089)
- hsa-let-7b-5p (MIRT052092)
- hsa-mir-590-3p (MIRT056644)
- hsa-mir-4709-3p (MIRT126944)
- hsa-mir-27a-3p (MIRT177532)
- hsa-mir-216a-3p (MIRT177533)
- hsa-mir-128-3p (MIRT177534)
- hsa-mir-3681-3p (MIRT177537)
- hsa-mir-507 (MIRT177539)
- hsa-mir-557 (MIRT177540)
- hsa-mir-888-5p (MIRT262609)
- hsa-mir-1468-3p (MIRT330541)
- hsa-mir-548f-5p (MIRT330542)
- hsa-mir-548g-5p (MIRT330543)
- hsa-mir-548x-5p (MIRT330544)
- hsa-mir-548aj-5p (MIRT330545)
- hsa-mir-4698 (MIRT330548)
- hsa-mir-548aw (MIRT330549)
- ebv-mir-bart7-3p (MIRT440488)
- hsa-mir-3685 (MIRT475555)
- hsa-mir-592 (MIRT475556)
- hsa-mir-514b-5p (MIRT475557)
- hsa-mir-513c-5p (MIRT475558)
- hsa-mir-155-3p (MIRT475559)
- hsa-mir-4711-3p (MIRT475560)
- hsa-mir-372-5p (MIRT475561)
- hsa-mir-371a-5p (MIRT475562)
- hsa-mir-616-5p (MIRT475563)
- hsa-mir-373-5p (MIRT475564)
- hsa-mir-371b-5p (MIRT475565)
- hsa-mir-5571-5p (MIRT475566)
- hsa-mir-16-1-3p (MIRT475567)
- hsa-mir-139-5p (MIRT475568)
- hsa-mir-101-3p (MIRT475569)
- hsa-mir-144-3p (MIRT475570)
- hsa-mir-3680-3p (MIRT502248)
- hsa-mir-450b-5p (MIRT502249)
- hsa-mir-4666b (MIRT502250)
- hsa-mir-5011-3p (MIRT502251)
- hsa-mir-4775 (MIRT502252)
- hsa-mir-6076 (MIRT502253)
- hsa-mir-6797-3p (MIRT502254)
- hsa-mir-539-5p (MIRT502255)
- hsa-mir-570-3p (MIRT502256)
- hsa-mir-488-5p (MIRT502257)
- hsa-mir-141-3p (MIRT502258)
- hsa-mir-200a-3p (MIRT502259)
- hsa-mir-6842-3p (MIRT511455)
- hsa-mir-647 (MIRT511456)
- hsa-mir-1273e (MIRT511457)
- hsa-mir-6514-3p (MIRT511458)
- hsa-mir-573 (MIRT511459)
- hsa-mir-3616-5p (MIRT511460)
- hsa-mir-6762-3p (MIRT511461)
- hsa-mir-604 (MIRT511462)
- hsa-mir-6882-3p (MIRT511463)
- hsa-mir-6811-3p (MIRT511464)
- hsa-mir-5585-5p (MIRT511465)
- hsa-mir-548ax (MIRT511466)
- hsa-mir-548ao-5p (MIRT511467)
- hsa-mir-302f (MIRT511468)
- hsa-mir-580-5p (MIRT511469)
- hsa-mir-6750-3p (MIRT511470)
- hsa-mir-3662 (MIRT511471)
- hsa-mir-214-5p (MIRT511472)
- hsa-mir-6780a-3p (MIRT557204)
- hsa-mir-6881-3p (MIRT557205)
- hsa-mir-7111-3p (MIRT557206)
- hsa-mir-7162-5p (MIRT557207)
- hsa-mir-516b-3p (MIRT557208)
- hsa-mir-516a-3p (MIRT557209)
- hsa-mir-361-3p (MIRT557210)
- hsa-mir-4506 (MIRT557211)
- hsa-mir-19a-3p (MIRT557212)
- hsa-mir-19b-3p (MIRT557213)
- hsa-mir-524-5p (MIRT562179)
- hsa-mir-3922-5p (MIRT562180)
- hsa-mir-520d-5p (MIRT562181)
- hsa-mir-651-3p (MIRT562182)
- hsa-mir-561-3p (MIRT562183)
- hsa-mir-224-5p (MIRT562184)
- hsa-mir-7856-5p (MIRT571996)
miRNA Products
- Search ViGene Biosciences for HNRNPF
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HNRNPF
- Browse OriGene Inhibitory RNA Products For HNRNPF
-
ViGene Biosciences ready-to-package AAV shRNAs for HNRNPF gene
Clone Products
-
OriGene ORF clones in human for HNRNPF
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for HNRNPF
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for HNRNPF
Cell Line Products
-
Horizon Cell Lines for HNRNPF
-
ViGene Biosciences adenoviral particle packaged cDNA for HNRNPF gene
-
ViGene Biosciences lentiviral particle packaged cDNA for HNRNPF gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HNRNPF gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for HNRNPF Gene
Localization for HNRNPF Gene
Subcellular locations from UniProtKB/Swiss-Prot for HNRNPF Gene
- Nucleus, nucleoplasm.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| mitochondrion | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | TAS | 7499401 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005681 | spliceosomal complex | IEA | -- |
| GO:0005829 | cytosol | IDA | -- |
| GO:0016020 | membrane | IDA | 19946888 |
Pathways & Interactions for HNRNPF Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | mRNA Splicing - Major Pathway |
.79
|
|
| 2 | Signaling by FGFR2 | ||
| 3 | Telomere Extension by Telomerase | ||
| 4 | mRNA Capping | ||
| 5 | Gene Expression |
.48
|
|
Pathways by source for HNRNPF Gene
1 BioSystems pathway for HNRNPF Gene
8 Reactome pathways for HNRNPF Gene
1 Qiagen pathway for HNRNPF Gene
Interacting Proteins for HNRNPF Gene
Selected Interacting proteins:
P52597-HNRPF_HUMAN
ENSP00000338477
for HNRNPF Gene via
MINT
IID
UniProtKB
STRING
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000398 | mRNA splicing, via spliceosome | TAS | -- |
| GO:0006396 | RNA processing | TAS | 7499401 |
| GO:0006397 | mRNA processing | IEA | -- |
| GO:0008380 | RNA splicing | IEA | -- |
| GO:0008543 | fibroblast growth factor receptor signaling pathway | TAS | -- |
No data available for SIGNOR curated interactions for HNRNPF Gene
Transcripts for HNRNPF Gene
mRNA/cDNA for HNRNPF Gene
- (6) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (902) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for HNRNPF Gene
- Heterogeneous nuclear ribonucleoprotein F:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for HNRNPF
-
Santa Cruz Biotechnology (SCBT) CRISPR for HNRNPF
- GenScript: Design CRISPR guide RNA sequences for HNRNPF
miRNA Products
- Search ViGene Biosciences for HNRNPF
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HNRNPF
- Browse OriGene Inhibitory RNA Products For HNRNPF
-
ViGene Biosciences ready-to-package AAV shRNAs for HNRNPF gene
Clone Products
-
OriGene ORF clones in human for HNRNPF
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for HNRNPF
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for HNRNPF
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b | ^ | 10a | · | 10b | · | 10c | · |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP12: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP13: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP14: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP15: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||
| SP16: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||
| SP17: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP18: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP19: | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP20: | - | - | - | - | - | - | - | - | - | - |
| ExUns: | 10d | · | 10e | · | 10f | · | 10g | · | 10h | · | 10i | · | 10j | · | 10k | · | 10l | · | 10m | · | 10n |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||||
| SP2: | |||||||||||||||||||||
| SP3: | |||||||||||||||||||||
| SP4: | |||||||||||||||||||||
| SP5: | |||||||||||||||||||||
| SP6: | |||||||||||||||||||||
| SP7: | |||||||||||||||||||||
| SP8: | |||||||||||||||||||||
| SP9: | |||||||||||||||||||||
| SP10: | |||||||||||||||||||||
| SP11: | |||||||||||||||||||||
| SP12: | |||||||||||||||||||||
| SP13: | |||||||||||||||||||||
| SP14: | |||||||||||||||||||||
| SP15: | |||||||||||||||||||||
| SP16: | |||||||||||||||||||||
| SP17: | |||||||||||||||||||||
| SP18: | |||||||||||||||||||||
| SP19: | |||||||||||||||||||||
| SP20: |
Expression for HNRNPF Gene
This gene is overexpressed in Peripheral blood mononuclear cells (8.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for HNRNPF Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of HNRNPF Gene:
HNRNPFSOURCE GeneReport for Unigene cluster for HNRNPF Gene:
Hs.808mRNA Expression by UniProt/SwissProt for HNRNPF Gene:
P52597-HNRPF_HUMAN
Tissue specificity:
Expressed ubiquitously.
Evidence on tissue expression from TISSUES for HNRNPF Gene
- Lung(4.8)
- Nervous system(4.8)
- Liver(4.7)
- Bone marrow(4.4)
- Intestine(4.3)
- Skin(3.9)
- Kidney(3.7)
- Eye(3.4)
- Blood(3.3)
- Pancreas(2.8)
- Spleen(2.5)
- Lymph node(2)
Primer Products
-
OriGene qPCR primer pairs for HNRNPF
-
OriGene qPCR primer pairs and template standards for HNRNPF
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for HNRNPF Gene
Orthologs for HNRNPF Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | HNRNPF 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Gm6430 35 |
|
OneToMany | |
| Hnrnpf 34 16 35 |
|
||||
| dog (Canis familiaris) |
Mammalia | HNRNPF 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Hnrnpf 34 |
|
||
| cow (Bos Taurus) |
Mammalia | HNRNPF 34 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | HNRNPF 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | HNRNPH1 35 |
|
OneToMany | |
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
OneToMany | |
| zebrafish (Danio rerio) |
Actinopterygii | hnrnph1l 35 |
|
ManyToMany | |
| hnrnph1 35 |
|
ManyToMany | |||
| worm (Caenorhabditis elegans) |
Secernentea | hrpf-1 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToMany |
- Species where no ortholog for HNRNPF was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Paralogs for HNRNPF Gene
(5) SIMAP similar genes for HNRNPF Gene using alignment to 1 proteins:
Pseudogenes.org Pseudogenes for HNRNPF Gene
Variants for HNRNPF Gene
| SNP ID | Clin | Chr 10 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000104704 | -- | 43,406,951(+) | TCTGT(A/G)AGAGC | intron-variant | |
| rs1000173525 | -- | 43,396,501(+) | AGCGC(A/G)GCTGG | utr-variant-5-prime | |
| rs1000176332 | -- | 43,404,952(+) | GGAAG(C/G)AATGC | intron-variant | |
| rs1000274732 | -- | 43,401,218(+) | CATTA(-/CCAT)CCATC | intron-variant | |
| rs1000335546 | -- | 43,408,117(+) | AGAGA(C/T)AGTCT | intron-variant, upstream-variant-2KB |
Residual Variation Intolerance Score:
22.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.04;
21.31% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for HNRNPF Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- HNRNPF
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HNRNPF Gene
Disorders for HNRNPF Gene
Relevant External Links for HNRNPF
No disorders were found for HNRNPF Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HNRNPF Gene
Publications for HNRNPF Gene
- Heterogeneous nuclear ribonucleoproteins H, H', and F are members of a ubiquitously expressed subfamily of related but distinct proteins encoded by genes mapping to different chromosomes. (PMID: 7499401) Honore B. … Celis J.E. (J. Biol. Chem. 1995) 2 3 4 64
- Structural basis of G-tract recognition and encaging by hnRNP F quasi-RRMs. (PMID: 20526337) Dominguez C. … Allain F.H. (Nat. Struct. Mol. Biol. 2010) 3 4 64
- Proteomic and functional analysis of Argonaute-containing mRNA- protein complexes in human cells. (PMID: 17932509) Hoeck J. … Meister G. (EMBO Rep. 2007) 3 4 64
- A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PMID: 16385451) Grupe A. … Goate A. (Am. J. Hum. Genet. 2006) 3 46 64
- NMR structure of the three quasi RNA recognition motifs (qRRMs) of human hnRNP F and interaction studies with Bcl-x G-tract RNA: a novel mode of RNA recognition. (PMID: 16885237) Dominguez C. … Allain F.H. (Nucleic Acids Res. 2006) 3 4 64
Products for HNRNPF Gene
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- Custom Antibody ServicesOriGene Antibodies for HNRNPF
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- OriGene qPCR primer pairs for HNRNPF
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- antibodies-online Antibodies for HNRNPF: See all 58
- antibodies-online Kits for HNRNPF: See all 24
- antibodies-online Proteins for HNRNPF: See all 12
- Search antibodies-online for peptides
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- VectorBuilder custom plasmid, inducible vectors for HNRNPF
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- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
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