Aliases for HNRNPD Gene
Aliases for HNRNPD Gene
External Ids for HNRNPD Gene
- HGNC: 5036
- Entrez Gene: 3184
- Ensembl: ENSG00000138668
- OMIM: 601324
- UniProtKB: Q14103
Previous HGNC Symbols for HNRNPD Gene
- AUF1
- HNRPD
Previous GeneCards Identifiers for HNRNPD Gene
- GC04M083494
- GC04M083274
- GC04M079015
Summaries for HNRNPD Gene
-
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants. [provided by RefSeq, Jul 2008]
GeneCards Summary for HNRNPD Gene
HNRNPD (Heterogeneous Nuclear Ribonucleoprotein D) is a Protein Coding gene. Diseases associated with HNRNPD include Chromosome 4Q21 Deletion Syndrome. Among its related pathways are mRNA Splicing - Major Pathway and Circadian rythm related genes. GO annotations related to this gene include nucleic acid binding and RNA binding. An important paralog of this gene is HNRNPAB.
UniProtKB/Swiss-Prot for HNRNPD Gene
-
Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3-UTR of many proto-oncogenes and cytokine mRNAs. Also binds to double- and single-stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5-UUAG-3 sequence and also weaker to the single-stranded 5-TTAGGG-3 telomeric DNA repeat. Binds RNA oligonucleotides with 5-UUAGGG-3 repeats more tightly than the telomeric single-stranded DNA 5-TTAGGG-3 repeats. Binding of RRM1 to DNA inhibits the formation of DNA quadruplex structure which may play a role in telomere elongation. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. May play a role in the regulation of the rhythmic expression of circadian clock core genes. Directly binds to the 3UTR of CRY1 mRNA and induces CRY1 rhythmic translation. May also be involved in the regulation of PER2 translation.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HNRNPD Gene
Genomics for HNRNPD Gene
Regulatory Elements for HNRNPD Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH04G082427 | 1.6 | Ensembl ENCODE dbSUPER | 12 | -55.0 | -54969 | 4.9 | HDGF HNRNPUL1 PKNOX1 MLX CREB3L1 WRNIP1 ARID4B SIN3A DMAP1 FEZF1 | HNRNPD ENOPH1 HNRNPDL ENSG00000202440 GC04M082403 |
| GH04G082284 | 1.2 | Ensembl ENCODE | 11.9 | +89.3 | 89323 | 1.6 | HDGF PKNOX1 ATF1 ARID4B YY1 GLIS2 ZNF143 SP3 SP5 NFYC | HNRNPD LOC105377307 LOC105377308 |
| GH04G082423 | 0.7 | dbSUPER | 12 | -49.3 | -49315 | 1.6 | ARNT AGO1 SIN3A POLR2A FOS BCLAF1 PAF1 ZBED1 ELF4 ZSCAN23 | HNRNPD ENOPH1 HNRNPDL GC04M082403 ENSG00000202440 |
| GH04G082394 | 0.6 | ENCODE | 11.7 | -20.5 | -20521 | 1.1 | TFE3 FOXA2 SAP130 HLF RAD51 FOS FOSL2 PRDM1 | HNRNPDL ENOPH1 HNRNPD TMEM150C IGBP1P4 |
| GH04G082283 | 0.4 | FANTOM5 | 11.9 | +90.4 | 90357 | 0.3 | SCRT2 | HNRNPD LOC105377307 BIN2P1 |
- Transcription factor binding sites by QIAGEN in the HNRNPD gene promoter:
Regulatory Element Products
Genomic Location for HNRNPD Gene
- Chromosome:
- 4
- Start:
- 82,352,498 bp from pter
- End:
- 82,374,503 bp from pter
- Size:
- 22,006 bases
- Orientation:
- Minus strand
Genomic View for HNRNPD Gene
- Cytogenetic band:
-
- 4q21.22 by Ensembl
- 4q21.22 by Entrez Gene
- 4q21.22 by HGNC
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HNRNPD Gene
Proteins for HNRNPD Gene
-
Protein details for HNRNPD Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q14103-HNRPD_HUMAN
- Recommended name:
- Heterogeneous nuclear ribonucleoprotein D0
- Protein Accession:
- Q14103
- A8K9J2
- P07029
- Q01858
- Q14100
- Q14101
- Q14102
- Q4W5A1
- Q9UCE8
- Q9UCE9
Protein attributes for HNRNPD Gene
- Size:
- 355 amino acids
- Molecular mass:
- 38434 Da
- Quaternary structure:
-
- Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs. Part of a complex associated with the FOS mCRD domain and consisting of PABPC1, PAIP1, CSDE1/UNR and SYNCRIP. Interacts with IGF2BP2. Interacts with GTPBP1. Interacts with EIF4G1; the interaction requires RNA. Interacts with EIF3B and RPS3.
- SequenceCaution:
-
- Sequence=AAA35781.1; Type=Frameshift; Positions=45, 59, 355; Evidence={ECO:0000305}; Sequence=AAA35781.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of unknown origin in the N-terminal part.; Evidence={ECO:0000305}; Sequence=CAA27544.1; Type=Miscellaneous discrepancy; Note=Several sequence conflicts.; Evidence={ECO:0000305};
Three dimensional structures from OCA and Proteopedia for HNRNPD Gene
Protein Expression for HNRNPD Gene
Post-translational modifications for HNRNPD Gene
- Arg-345 is dimethylated, probably to asymmetric dimethylarginine.
- Methylated by PRMT1, in an insulin-dependent manner. The PRMT1-mediated methylation regulates tyrosine phosphorylation (By similarity).
- Ubiquitination at isoforms=2, 3, 4114, posLast=119119, posLast=183183, isoforms=2, 3, 4231, posLast=260260, and isoforms=4292
- Modification sites at PhosphoSitePlus
Other Protein References for HNRNPD Gene
Antibody Products
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-
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Protein Products
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- antibodies-online Proteins for HNRNPD: See all 11
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Assay Products
- antibodies-online Kits for HNRNPD: See all 23
No data available for DME Specific Peptides for HNRNPD Gene
Domains & Families for HNRNPD Gene
Gene Families for HNRNPD Gene
Protein Domains for HNRNPD Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for HNRNPD Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for HNRNPD Gene
Function for HNRNPD Gene
Molecular function for HNRNPD Gene
- UniProtKB/Swiss-Prot Function:
- Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3-UTR of many proto-oncogenes and cytokine mRNAs. Also binds to double- and single-stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5-UUAG-3 sequence and also weaker to the single-stranded 5-TTAGGG-3 telomeric DNA repeat. Binds RNA oligonucleotides with 5-UUAGGG-3 repeats more tightly than the telomeric single-stranded DNA 5-TTAGGG-3 repeats. Binding of RRM1 to DNA inhibits the formation of DNA quadruplex structure which may play a role in telomere elongation. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. May play a role in the regulation of the rhythmic expression of circadian clock core genes. Directly binds to the 3UTR of CRY1 mRNA and induces CRY1 rhythmic translation. May also be involved in the regulation of PER2 translation.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003680 | AT DNA binding | IEA | -- |
| GO:0003682 | chromatin binding | IEA | -- |
| GO:0003723 | RNA binding | TAS,NAS | 3754960 |
Phenotypes for HNRNPD Gene
- MGI mutant phenotypes for HNRNPD:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for HNRNPD:
-
- Increased viability
- Increased vaccinia virus (VACV) infection
- Decreased hepcidin::fluc mRNA expression
- Dynamic nuclei (hole, folded or small irregular)
- Decreased POU5F1-GFP protein expression
- Increased HPV18 LCR reporter activity
- Increased HPV16-GFP infection
- Synthetic lethal with vaccinia virus (VACV) infection
- Decreased OCT4 protein expression
- Decreased NANOG protein expression
Animal Model Products
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miRNA for HNRNPD Gene
- miRTarBase miRNAs that target HNRNPD
-
- hsa-mir-197-3p (MIRT004177)
- hsa-mir-1-3p (MIRT024012)
- hsa-mir-221-3p (MIRT024179)
- hsa-mir-1229-3p (MIRT036291)
- hsa-mir-18a-3p (MIRT040890)
- hsa-mir-222-3p (MIRT046797)
- hsa-mir-146b-5p (MIRT437903)
- hsa-mir-141-3p (MIRT437904)
- hsa-mir-18b-3p (MIRT536773)
- hsa-mir-6782-3p (MIRT536774)
- hsa-mir-3613-3p (MIRT536775)
- hsa-mir-548ay-3p (MIRT536776)
- hsa-mir-548at-3p (MIRT536777)
- hsa-mir-548as-3p (MIRT536778)
- hsa-mir-548t-3p (MIRT536779)
- hsa-mir-548ap-3p (MIRT536780)
- hsa-mir-548aa (MIRT536781)
- hsa-mir-450a-2-3p (MIRT536782)
- hsa-mir-6857-5p (MIRT536783)
- hsa-mir-6763-5p (MIRT536784)
- hsa-mir-3150a-3p (MIRT536785)
- hsa-mir-6810-5p (MIRT536786)
- hsa-mir-2110 (MIRT536787)
- hsa-mir-3147 (MIRT536788)
- hsa-mir-4450 (MIRT536789)
- hsa-mir-4425 (MIRT536790)
miRNA Products
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Horizon Cell Lines for HNRNPD
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Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for HNRNPD Gene
Localization for HNRNPD Gene
Subcellular locations from UniProtKB/Swiss-Prot for HNRNPD Gene
- Nucleus. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Component of ribonucleosomes. Cytoplasmic localization oscillates diurnally.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | TAS,NAS | 1433497 |
| GO:0005654 | nucleoplasm | TAS,IDA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
| GO:0019013 | viral nucleocapsid | IEA | -- |
Pathways & Interactions for HNRNPD Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | mRNA Splicing - Major Pathway |
.79
|
.41
|
| 2 | CDK-mediated phosphorylation and removal of Cdc6 | ||
| 3 | Translational Control | ||
| 4 | Telomere Extension by Telomerase | ||
| 5 | Gene Expression |
.48
|
|
Pathways by source for HNRNPD Gene
1 Cell Signaling Technology pathway for HNRNPD Gene
2 BioSystems pathways for HNRNPD Gene
6 Reactome pathways for HNRNPD Gene
1 Qiagen pathway for HNRNPD Gene
Interacting Proteins for HNRNPD Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000398 | mRNA splicing, via spliceosome | TAS | -- |
| GO:0000723 | telomere maintenance | ISS | -- |
| GO:0001889 | liver development | IEA | -- |
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | NAS | 1433497 |
Transcripts for HNRNPD Gene
mRNA/cDNA for HNRNPD Gene
- (4) REFSEQ mRNAs :
- (15) Additional mRNA sequences :
- (577) Selected AceView cDNA sequences:
- (12) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for HNRNPD Gene
CRISPR Products
-
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miRNA Products
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Clone Products
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Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | · | 9c | ^ | 10a | · | 10b | · | 10c | ^ | 11a | · | 11b | ^ | 12a | · | 12b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP9: | |||||||||||||||||||||||||||||||||||||||||||
| SP10: | |||||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - |
Expression for HNRNPD Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for HNRNPD Gene
NURSA nuclear receptor signaling pathways regulating expression of HNRNPD Gene:
HNRNPDSOURCE GeneReport for Unigene cluster for HNRNPD Gene:
Hs.480073Evidence on tissue expression from TISSUES for HNRNPD Gene
- Lung(4.7)
- Liver(4.5)
- Blood(4.4)
- Nervous system(4.2)
- Muscle(2.7)
- Thyroid gland(2.7)
- Kidney(2.6)
- Intestine(2.5)
- Spleen(2.5)
- Heart(2.3)
- Bone marrow(2.2)
- Lymph node(2.2)
- Skin(2)
- Stomach(2)
Primer Products
-
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-
OriGene qPCR primer pairs for HNRNPD
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for HNRNPD Gene
Orthologs for HNRNPD Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| platypus (Ornithorhynchus anatinus) |
Mammalia | HNRNPD 35 |
|
OneToOne | |
| chimpanzee (Pan troglodytes) |
Mammalia | HNRNPD 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | HNRPD 35 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | HNRNPD 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Hnrnpd 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Hnrpd 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | HNRNPD 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | HNRNPD 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | HNRNPD 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | hnrnpd 34 |
|
||
| Str.8893 34 |
|
||||
| zebrafish (Danio rerio) |
Actinopterygii | hnrnpd 34 35 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | sqd 35 |
|
OneToMany | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | HRP1 35 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.5495 35 |
|
ManyToMany | |
| CSA.10292 35 |
|
ManyToMany |
- Species where no ortholog for HNRNPD was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for HNRNPD Gene
Paralogs for HNRNPD Gene
(34) SIMAP similar genes for HNRNPD Gene using alignment to 10 proteins:
Pseudogenes.org Pseudogenes for HNRNPD Gene
Variants for HNRNPD Gene
| SNP ID | Clin | Chr 04 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000020840 | -- | 82,372,187(+) | AAAAG(A/G)AATGG | intron-variant, upstream-variant-2KB | |
| rs1000140846 | -- | 82,373,033(+) | CAAAC(A/G)GAGAA | intron-variant, upstream-variant-2KB | |
| rs1000264328 | -- | 82,373,634(+) | CCGTT(-/GCC)GCCGC | upstream-variant-2KB, cds-indel | |
| rs10003180 | -- | 82,367,272(+) | TAAGG(G/T)AAACT | intron-variant | |
| rs1000346487 | -- | 82,363,694(+) | GAGTA(A/T)CTTAA | intron-variant |
Relevant External Links for HNRNPD Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HNRNPD Gene
Disorders for HNRNPD Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| chromosome 4q21 deletion syndrome |
|
|
Relevant External Links for HNRNPD
No data available for UniProtKB/Swiss-Prot and Genatlas for HNRNPD Gene
Publications for HNRNPD Gene
- Structure and interactions with RNA of the N-terminal UUAG-specific RNA-binding domain of hnRNP D0. (PMID: 10080887) Nagata T. … Katahira M. (J. Mol. Biol. 1999) 3 4 22 64
- The human HNRPD locus maps to 4q21 and encodes a highly conserved protein. (PMID: 9615222) Dempsey L.A. … Maizels N. (Genomics 1998) 2 3 4 64
- Structure and genomic organization of the human AUF1 gene: alternative pre-mRNA splicing generates four protein isoforms. (PMID: 9521873) Wagner B.J. … Brewer G. (Genomics 1998) 3 4 22 64
- The UUAG-specific RNA binding protein, heterogeneous nuclear ribonucleoprotein D0. Common modular structure and binding properties of the 2xRBD-Gly family. (PMID: 7673195) Kajita Y. … Ishikawa F. (J. Biol. Chem. 1995) 3 4 22 64
- AUF1 contributes to Cryptochrome1 mRNA degradation and rhythmic translation. (PMID: 24423872) Lee K.H. … Kim K.T. (Nucleic Acids Res. 2014) 3 4 64
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- antibodies-online Proteins for HNRNPD: See all 11
- Search antibodies-online for peptides
- GeneTex HNRNPD antibody for HNRNPD
- Search GeneTex for Proteins for HNRNPD
- ViGene Biosciences adenoviral particle packaged cDNA for HNRNPD gene
- ViGene Biosciences lentiviral particle packaged cDNA for HNRNPD gene
- ViGene Biosciences ready-to-package AAV shRNAs for HNRNPD gene
- Search ViGene Biosciences for HNRNPD
- Santa Cruz Biotechnology (SCBT) Antibodies for HNRNPD
- Search Santa Cruz Biotechnology (SCBT) for HNRNPD siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for HNRNPD
- Horizon Cell Lines for HNRNPD
- Cyagen custom Knockout/knockin (KOKI) mouse models for HNRNPD
- VectorBuilder custom plasmid, inducible vectors for HNRNPD
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HNRNPD
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for HNRNPD Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer




