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HNRNPCL2 Gene(Protein Coding)

Heterogeneous Nuclear Ribonucleoprotein C-Like 2

GCID:
GC01M013115
GIFtS:
20
Genes Participants
UDN Logo

Aliases for HNRNPCL2 Gene

Aliases for HNRNPCL2 Gene

  • Heterogeneous Nuclear Ribonucleoprotein C-Like 2 2 3 5
  • Heterogeneous Nuclear Ribonucleoprotein C Pseudogene 5 2 3
  • HnRNP C-Like-2 3 4
  • HNRNPCP5 3 4

External Ids for HNRNPCL2 Gene

Previous HGNC Symbols for HNRNPCL2 Gene

  • HNRNPCP5

Summaries for HNRNPCL2 Gene

GeneCards Summary for HNRNPCL2 Gene

HNRNPCL2 (Heterogeneous Nuclear Ribonucleoprotein C-Like 2) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is HNRNPCL1.

UniProtKB/Swiss-Prot for HNRNPCL2 Gene

  • May play a role in nucleosome assembly by neutralizing basic proteins such as A and B core hnRNPs.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HNRNPCL2 Gene

Genomics for HNRNPCL2 Gene

Products:

  1. Regulatory Element

Genomic Location for HNRNPCL2 Gene

Chromosome:
1
Start:
13,115,488 bp from pter
End:
13,116,854 bp from pter
Size:
1,367 bases
Orientation:
Minus strand

Genomic View for HNRNPCL2 Gene

Genes around HNRNPCL2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HNRNPCL2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HNRNPCL2 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for HNRNPCL2 Gene

No data available for Regulatory Elements for HNRNPCL2 Gene

Proteins for HNRNPCL2 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for HNRNPCL2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    B2RXH8-HNRC2_HUMAN
    Recommended name:
    Heterogeneous nuclear ribonucleoprotein C-like 2
    Protein Accession:
    B2RXH8
    Secondary Accessions:
    • B7ZW41

    Protein attributes for HNRNPCL2 Gene

    Size:
    293 amino acids
    Molecular mass:
    32072 Da
    Quaternary structure:
    No Data Available

neXtProt entry for HNRNPCL2 Gene

Post-translational modifications for HNRNPCL2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for HNRNPCL2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for HNRNPCL2 Gene

Domains & Families for HNRNPCL2 Gene

Protein Domains for HNRNPCL2 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

B2RXH8

UniProtKB/Swiss-Prot:

HNRC2_HUMAN :
  • Belongs to the RRM HNRPC family. RALY subfamily.
Family:
  • Belongs to the RRM HNRPC family. RALY subfamily.
genes like me logo Genes that share domains with HNRNPCL2: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for HNRNPCL2 Gene

Function for HNRNPCL2 Gene

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  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Molecular function for HNRNPCL2 Gene

UniProtKB/Swiss-Prot Function:
May play a role in nucleosome assembly by neutralizing basic proteins such as A and B core hnRNPs.

Gene Ontology (GO) - Molecular Function for HNRNPCL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003723 RNA binding IEA --
genes like me logo Genes that share ontologies with HNRNPCL2: view

Inhibitory RNA Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HNRNPCL2 Gene

Localization for HNRNPCL2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for HNRNPCL2 Gene

Nucleus. Note=Component of ribonucleosomes. {ECO:0000250}.

Gene Ontology (GO) - Cellular Components for HNRNPCL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
GO:0030529 intracellular ribonucleoprotein complex IEA --
genes like me logo Genes that share ontologies with HNRNPCL2: view

No data available for Subcellular locations from COMPARTMENTS for HNRNPCL2 Gene

Pathways & Interactions for HNRNPCL2 Gene

SuperPathways for HNRNPCL2 Gene

PathCards logo More details on SuperPathways for HNRNPCL2
No Data Available

Interacting Proteins for HNRNPCL2 Gene

Selected Interacting proteins: B2RXH8-HNRC2_HUMAN for HNRNPCL2 Gene via UniProtKB IID

Gene Ontology (GO) - Biological Process for HNRNPCL2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for HNRNPCL2 Gene

Drugs & Compounds for HNRNPCL2 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for HNRNPCL2 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

mRNA/cDNA for HNRNPCL2 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for HNRNPCL2 Gene

No ASD Table

Relevant External Links for HNRNPCL2 Gene

GeneLoc Exon Structure for
HNRNPCL2
ECgene alternative splicing isoforms for
HNRNPCL2

Expression for HNRNPCL2 Gene

Products:

  1. Primer

NURSA nuclear receptor signaling pathways regulating expression of HNRNPCL2 Gene:

HNRNPCL2
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HNRNPCL2 Gene

Orthologs for HNRNPCL2 Gene

Evolution for HNRNPCL2 Gene

ENSEMBL:
Gene Tree for HNRNPCL2 (if available)
TreeFam:
Gene Tree for HNRNPCL2 (if available)

No data available for Orthologs for HNRNPCL2 Gene

Paralogs for HNRNPCL2 Gene

Paralogs for HNRNPCL2 Gene

genes like me logo Genes that share paralogs with HNRNPCL2: view

Variants for HNRNPCL2 Gene

Sequence variations from dbSNP and Humsavar for HNRNPCL2 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1002232719 -- 13,117,918(+) CAGCT(G/T)GCTCT upstream-variant-2KB
rs1002601034 -- 13,118,089(+) ACTAC(A/T)GATGC upstream-variant-2KB
rs1002618846 -- 13,116,940(+) CCACG(A/T)ATCCG upstream-variant-2KB
rs1002696828 -- 13,118,115(+) GCTCT(A/G)CAAGG upstream-variant-2KB
rs1002748315 -- 13,117,669(+) AGAAT(A/G)AAGAT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for HNRNPCL2 Gene

Variant ID Type Subtype PubMed ID
dgv137n54 CNV loss 21841781
dgv17n67 CNV gain 20364138
esv2675846 CNV deletion 23128226
esv2743964 CNV deletion 23290073
esv2743975 CNV deletion 23290073
esv3577737 CNV loss 25503493
esv3577740 CNV loss 25503493
esv3585255 CNV loss 21293372
esv3585256 CNV loss 21293372
esv3585257 CNV gain 21293372
esv8453 CNV loss 19470904
nsv1075775 CNV duplication 25765185
nsv1122300 CNV deletion 24896259
nsv1150505 CNV duplication 26484159
nsv2965 CNV deletion 18451855
nsv545541 CNV loss 21841781
nsv7172 OTHER inversion 18451855
nsv821333 CNV duplication 20802225
nsv8768 CNV gain+loss 18304495
nsv953504 CNV duplication 24416366

Relevant External Links for HNRNPCL2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HNRNPCL2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HNRNPCL2 Gene

Disorders for HNRNPCL2 Gene

Relevant External Links for HNRNPCL2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HNRNPCL2

No disorders were found for HNRNPCL2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HNRNPCL2 Gene

Publications for HNRNPCL2 Gene

  1. Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. (PMID: 17643375) Jeronimo C. … Coulombe B. (Mol. Cell 2007) 3 64
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for HNRNPCL2 Gene

Sources for HNRNPCL2 Gene

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