Aliases for HNRNPA1L2 Gene
Aliases for HNRNPA1L2 Gene
External Ids for HNRNPA1L2 Gene
- HGNC: 27067
- Entrez Gene: 144983
- Ensembl: ENSG00000139675
- UniProtKB: Q32P51
Previous GeneCards Identifiers for HNRNPA1L2 Gene
- GC13P052092
- GC13P053192
- GC13P033905
Summaries for HNRNPA1L2 Gene
GeneCards Summary for HNRNPA1L2 Gene
HNRNPA1L2 (Heterogeneous Nuclear Ribonucleoprotein A1-Like 2) is a Protein Coding gene. Among its related pathways are mRNA Splicing - Major Pathway. GO annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is HNRNPA1.
UniProtKB/Swiss-Prot for HNRNPA1L2 Gene
-
Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection.
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HNRNPA1L2 Gene
Genomics for HNRNPA1L2 Gene
Regulatory Elements for HNRNPA1L2 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH13G052404 | 0.8 | ENCODE | 3.9 | -211.8 | -211796 | 2.3 | ZSCAN5A KLF1 SUZ12 ZNF76 SIN3A YY1 ZFHX2 GLIS2 GATA2 POLR2A | TPTE2P2 HNRNPA1L2 THSD1 RNY4P24 |
| GH13G052616 | 1.4 | FANTOM5 ENCODE | 0.7 | +0.0 | 11 | 2.0 | PKNOX1 MLX ARNT ZFP64 WRNIP1 ARID4B SIN3A DMAP1 ZNF2 YY1 | TPTE2P2 HNRNPA1L2 ENSG00000273723 |
| GH13G052779 | 0.3 | FANTOM5 | 1.5 | +161.7 | 161722 | 0.1 | PCDH8 HNRNPA1L2 LOC105370209 MIR759 | |
| GH13G052623 | 1 | Ensembl ENCODE | 0.4 | +6.6 | 6629 | 1.0 | CTCF PKNOX1 BMI1 RAD21 SMC3 IKZF2 RFX1 ZNF654 MTA2 BHLHE40 | TPTE2P2 HNRNPA1L2 ENSG00000273723 |
| GH13G052606 | 0.5 | Ensembl | 0.4 | -10.6 | -10570 | 0.6 | ATF3 CEBPA CEBPB CEBPG ZIC2 | CKAP2 TPTE2P2 LINC00345 HNRNPA1L2 |
- Transcription factor binding sites by QIAGEN in the HNRNPA1L2 gene promoter:
Regulatory Element Products
Genomic Location for HNRNPA1L2 Gene
- Chromosome:
- 13
- Start:
- 52,617,470 bp from pter
- End:
- 52,643,796 bp from pter
- Size:
- 26,327 bases
- Orientation:
- Plus strand
Genomic View for HNRNPA1L2 Gene
- Cytogenetic band:
-
- 13q14.3 by Ensembl
- 13q14.3 by Entrez Gene
- 13q14.3 by HGNC
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HNRNPA1L2 Gene
Proteins for HNRNPA1L2 Gene
-
Protein details for HNRNPA1L2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q32P51-RA1L2_HUMAN
- Recommended name:
- Heterogeneous nuclear ribonucleoprotein A1-like 2
- Protein Accession:
- Q32P51
- Q5TBS2
Protein attributes for HNRNPA1L2 Gene
- Size:
- 320 amino acids
- Molecular mass:
- 34225 Da
- Quaternary structure:
- No Data Available
Protein Expression for HNRNPA1L2 Gene
Post-translational modifications for HNRNPA1L2 Gene
Other Protein References for HNRNPA1L2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for HNRNPA1L2
-
Abcam antibodies for HNRNPA1L2
- Invitrogen Antibodies for HNRNPA1L2
- GeneTex HNRNPA1L2 antibody for HNRNPA1L2
-
Santa Cruz Biotechnology (SCBT) Antibodies for HNRNPA1L2
Protein Products
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- antibodies-online Proteins for HNRNPA1L2: See all 3
- Search antibodies-online for peptides
- Search GeneTex for Proteins for HNRNPA1L2
Assay Products
No data available for DME Specific Peptides for HNRNPA1L2 Gene
Domains & Families for HNRNPA1L2 Gene
Gene Families for HNRNPA1L2 Gene
Protein Domains for HNRNPA1L2 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for HNRNPA1L2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for HNRNPA1L2 Gene
Function for HNRNPA1L2 Gene
Molecular function for HNRNPA1L2 Gene
- UniProtKB/Swiss-Prot Function:
- Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0003723 | RNA binding | IEA | -- |
Phenotypes for HNRNPA1L2 Gene
- GenomeRNAi human phenotypes for HNRNPA1L2:
Animal Model Products
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ViGene Biosciences lentiviral particle packaged cDNA for HNRNPA1L2 gene
-
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- Search ViGene Biosciences for HNRNPA1L2
CRISPR Products
-
OriGene CRISPR knockouts for HNRNPA1L2
-
Santa Cruz Biotechnology (SCBT) CRISPR for HNRNPA1L2
- GenScript: Design CRISPR guide RNA sequences for HNRNPA1L2
miRNA for HNRNPA1L2 Gene
- miRTarBase miRNAs that target HNRNPA1L2
-
- hsa-mir-1-3p (MIRT023805)
- hsa-mir-30a-5p (MIRT028493)
- hsa-mir-129-5p (MIRT573995)
- hsa-mir-4444 (MIRT573996)
- hsa-mir-466 (MIRT573997)
- hsa-mir-4641 (MIRT573998)
- hsa-mir-496 (MIRT573999)
- hsa-mir-1910-5p (MIRT574000)
- hsa-mir-4643 (MIRT574001)
- hsa-mir-4789-3p (MIRT574002)
- hsa-mir-3169 (MIRT693894)
- hsa-mir-2113 (MIRT693895)
- hsa-mir-3674 (MIRT693896)
- hsa-mir-218-5p (MIRT693897)
- hsa-mir-6842-3p (MIRT693898)
- hsa-mir-647 (MIRT693899)
- hsa-mir-4715-3p (MIRT693900)
- hsa-mir-6844 (MIRT693901)
- hsa-mir-513b-5p (MIRT693902)
- hsa-mir-4524b-5p (MIRT693903)
- hsa-mir-4524a-5p (MIRT693904)
- hsa-mir-3613-5p (MIRT693905)
- hsa-mir-636 (MIRT693906)
- hsa-mir-6775-3p (MIRT693907)
- hsa-mir-1291 (MIRT693908)
- hsa-mir-8077 (MIRT693909)
- hsa-mir-6799-3p (MIRT693910)
- hsa-mir-3173-5p (MIRT693911)
- hsa-mir-4778-3p (MIRT693912)
- hsa-mir-367-5p (MIRT693913)
- hsa-mir-1267 (MIRT693914)
- hsa-mir-7157-3p (MIRT693915)
- hsa-mir-6737-3p (MIRT693916)
- hsa-mir-5008-3p (MIRT693917)
- hsa-mir-3137 (MIRT693918)
- hsa-mir-4682 (MIRT693919)
- hsa-mir-6727-3p (MIRT693920)
- hsa-mir-4722-3p (MIRT693921)
- hsa-mir-6752-3p (MIRT693922)
- hsa-mir-4719 (MIRT693923)
- hsa-mir-4762-5p (MIRT693924)
- hsa-mir-4747-3p (MIRT693925)
- hsa-mir-646 (MIRT693926)
- hsa-mir-503-5p (MIRT693927)
- hsa-mir-6838-5p (MIRT693928)
- hsa-mir-497-5p (MIRT693929)
- hsa-mir-424-5p (MIRT693930)
- hsa-mir-195-5p (MIRT693931)
- hsa-mir-16-5p (MIRT693932)
- hsa-mir-15b-5p (MIRT693933)
- hsa-mir-15a-5p (MIRT693934)
- hsa-mir-649 (MIRT693935)
- hsa-mir-490-3p (MIRT693936)
- hsa-mir-8057 (MIRT693937)
- hsa-mir-3191-5p (MIRT693938)
- hsa-mir-4279 (MIRT693939)
- hsa-mir-7111-3p (MIRT693940)
- hsa-mir-670-5p (MIRT693941)
- hsa-mir-668-3p (MIRT693942)
- hsa-mir-760 (MIRT693943)
- hsa-mir-6822-3p (MIRT693944)
- hsa-mir-942-5p (MIRT693945)
- hsa-mir-6773-3p (MIRT693946)
- hsa-mir-6504-5p (MIRT693947)
- hsa-mir-3064-5p (MIRT693948)
- hsa-mir-149-5p (MIRT693949)
- hsa-mir-664a-5p (MIRT693950)
- hsa-mir-4794 (MIRT693951)
- hsa-mir-6824-3p (MIRT693952)
- hsa-mir-6764-3p (MIRT693953)
- hsa-mir-330-5p (MIRT693954)
- hsa-mir-326 (MIRT693955)
- hsa-mir-518c-5p (MIRT693956)
- hsa-mir-6845-3p (MIRT693957)
- hsa-mir-1976 (MIRT693958)
- hsa-mir-3653-5p (MIRT693959)
- hsa-mir-6893-3p (MIRT693960)
- hsa-mir-370-3p (MIRT693961)
- hsa-mir-6769b-3p (MIRT693962)
- hsa-mir-4723-3p (MIRT693963)
- hsa-mir-3183 (MIRT693964)
- hsa-mir-339-5p (MIRT693965)
miRNA Products
- Search ViGene Biosciences for HNRNPA1L2
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for HNRNPA1L2
- Browse OriGene Inhibitory RNA Products For HNRNPA1L2
-
ViGene Biosciences ready-to-package AAV shRNAs for HNRNPA1L2 gene
Cell Line Products
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Horizon Cell Lines for HNRNPA1L2
-
ViGene Biosciences adenoviral particle packaged cDNA for HNRNPA1L2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for HNRNPA1L2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HNRNPA1L2 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for HNRNPA1L2 Gene
Localization for HNRNPA1L2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for HNRNPA1L2 Gene
- Nucleus. Cytoplasm.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005681 | spliceosomal complex | IEA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0019013 | viral nucleocapsid | IEA | -- |
| GO:0030529 | intracellular ribonucleoprotein complex | IEA | -- |
Pathways & Interactions for HNRNPA1L2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | mRNA Splicing - Major Pathway |
.50
|
|
Pathways by source for HNRNPA1L2 Gene
1 KEGG pathway for HNRNPA1L2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006397 | mRNA processing | IEA | -- |
| GO:0006810 | transport | IEA | -- |
| GO:0008380 | RNA splicing | IEA | -- |
| GO:0051028 | mRNA transport | IEA | -- |
No data available for SIGNOR curated interactions for HNRNPA1L2 Gene
Transcripts for HNRNPA1L2 Gene
mRNA/cDNA for HNRNPA1L2 Gene
- (2) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (37) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for HNRNPA1L2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for HNRNPA1L2
-
Santa Cruz Biotechnology (SCBT) CRISPR for HNRNPA1L2
- GenScript: Design CRISPR guide RNA sequences for HNRNPA1L2
miRNA Products
- Search ViGene Biosciences for HNRNPA1L2
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for HNRNPA1L2
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ViGene Biosciences ready-to-package AAV shRNAs for HNRNPA1L2 gene
Flow Cytometry Products
Expression for HNRNPA1L2 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for HNRNPA1L2 Gene
NURSA nuclear receptor signaling pathways regulating expression of HNRNPA1L2 Gene:
HNRNPA1L2SOURCE GeneReport for Unigene cluster for HNRNPA1L2 Gene:
Hs.447506Evidence on tissue expression from TISSUES for HNRNPA1L2 Gene
- Nervous system(4.3)
- Skin(4)
Primer Products
-
OriGene qPCR primer pairs for HNRNPA1L2
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for HNRNPA1L2 Gene
Orthologs for HNRNPA1L2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | HNRNPA1L2 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Gm7729 35 |
|
ManyToMany | |
| Gm5803 34 16 |
|
||||
| cow (Bos Taurus) |
Mammalia | LOC100848353 34 |
|
||
| HNRNPA1L2 35 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | LOC608729 34 |
|
||
| HNRNPA1L2 35 |
|
OneToOne | |||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 35 |
|
OneToMany | |
| oppossum (Monodelphis domestica) |
Mammalia | HNRNPA1L2 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
OneToMany |
- Species where no ortholog for HNRNPA1L2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for HNRNPA1L2 Gene
Paralogs for HNRNPA1L2 Gene
(13) SIMAP similar genes for HNRNPA1L2 Gene using alignment to 1 proteins:
Variants for HNRNPA1L2 Gene
| SNP ID | Clin | Chr 13 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000165340 | -- | 52,630,925(+) | TACTG(A/T)GCAGC | intron-variant | |
| rs1000218296 | -- | 52,630,563(+) | ACCAC(G/T)CCCGG | intron-variant | |
| rs1000275863 | -- | 52,616,274(+) | CCTGT(A/G)GTTCT | upstream-variant-2KB | |
| rs1000426176 | -- | 52,636,868(+) | GCTCT(A/G)TCACC | intron-variant | |
| rs1000626250 | -- | 52,616,008(+) | AATAG(A/G)ATGAA | upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv1653n100 | CNV | gain | 25217958 |
| esv3632103 | CNV | loss | 21293372 |
| esv3892344 | CNV | loss | 25118596 |
| esv3892345 | CNV | gain | 25118596 |
| nsv1044949 | CNV | gain | 25217958 |
| nsv819201 | CNV | gain | 19587683 |
| nsv820041 | CNV | gain | 19587683 |
| nsv976119 | CNV | duplication | 23825009 |
Relevant External Links for HNRNPA1L2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- HNRNPA1L2
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HNRNPA1L2 Gene
Disorders for HNRNPA1L2 Gene
Relevant External Links for HNRNPA1L2
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- HNRNPA1L2
No disorders were found for HNRNPA1L2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HNRNPA1L2 Gene
Publications for HNRNPA1L2 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
- Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage. (PMID: 25963833) Drissi R. … Boisvert F.M. (Mol. Cell Proteomics 2015) 3 64
- The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
- Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3 64
Products for HNRNPA1L2 Gene
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- VectorBuilder custom plasmid, inducible vectors for HNRNPA1L2
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- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for HNRNPA1L2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
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