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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

HNF1A-AS1 Gene

RNA gene GIFtS: 22
GCID: GC12M121406

HNF1A antisense RNA 1

(Previous names: chromosome 12 open reading frame 27, non-protein coding...)
(Previous symbols: C12orf27, NCRNA00262)

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(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Subcategory (RNA class): antisense

Quality score for this RNA gene is 3

Aliases
HNF1A Antisense RNA 1¹ ²		Chromosome 12 Open Reading Frame 27¹
C12orf27¹ ²		HNF1A Antisense RNA 1 (Non-Protein Coding)¹
NCRNA00262¹ ²		Non-Protein Coding RNA 262¹
FLJ38690¹

External Ids:	HGNC: 26785¹	Entrez Gene: 283460²	Ensembl: ENSG00000241388⁷

Export aliases for HNF1A-AS1 gene to outside databases

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000012.11 NC_018923.1 NT_009775.17

Regulatory elements:

Search SABiosciences Regulatory transcription factor binding sites for HNF1A-AS1
Other transcription factors

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Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HNF1A-AS1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24.31 Ensembl cytogenetic band: 12q24.31 HGNC cytogenetic band: 12q24.31

HNF1A-AS1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HNF1A-AS1 gene location

GeneLoc information about chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12M121406: view genomic region (about GC identifiers)

Start:	121,406,416 bp from pter	End:	121,418,768 bp from pter
Size:	12,353 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
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UniProtKB: --

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
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Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for HNF1A-AS1

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
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(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
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REFSEQ mRNAs for HNF1A-AS1 gene:

NM_178513.2

Unigene Cluster for HNF1A-AS1:

HNF1A antisense RNA 1

Hs.612351 [show with all ESTs]

Unigene Representative Sequence: AK096009

4 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000537361 ENST00000539163(uc010szm.1) ENST00000433033 ENST00000535301

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Additional cDNA sequence:

AK096009.1 NR_024345.1

1 DOTS entry:

DT.40285616

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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Expression evidence for HNF1A-AS1:none

HNF1A-AS1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

HNF1A-AS1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

DKK1-induced cells (Derivation of cardio...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

SOURCE GeneReport for Unigene cluster: Hs.612351

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In Situ
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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

--

ENSEMBL Gene Tree for HNF1A-AS1 (if available)
TreeFam Gene Tree for HNF1A-AS1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
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SNP ID	Valid	Clinical significance	Chr 12 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs77894739^1,2	C,F,	--	121407178(+)	`CTTAGG/AGCCTT`	1	--	ds500¹		1		WA	118
rs12815613^1,2	C,F,H,	--	121407256(+)	`AAGGGA/GTACTC`	1	--	ds500¹		23		NS EA NA CSA WA	2758
rs187044177^1,2		--	121407336(+)	`CGGCTC/TGCAGC`	1	--	ds500¹		0	--	--	--	--
rs143048933^1,2		--	121407385(+)	`AGCCAA/CCCGAG`	1	--	ds500¹		0	--	--	--	--
rs146136690^1,2		--	121407451(+)	`AGAGAC/TGGGGT`	1	--	ds500¹		0	--	--	--	--
rs192889283^1,2		--	121407696(+)	`TCGACC/TCACTG`	1	--	nc-transcript-variant		0	--	--	--	--
rs11611273^1,2	C,H	--	121407726(+)	`tcaagC/CA /T/TGaattc`	3	--	nc-transcript-variant		0	--	--	--	--
rs75062321^1,2	F	--	121407726(+)	`TCAAGC/TAATTC`	1	--	nc-transcript-variant		1		NA	4
rs11615249^1,2	C,F,H	--	121407727(+)	`caagcG/Aattct`	1	--	nc-transcript-variant		1		NA	4
rs111389084^1,2	C,	--	121407739(+)	`CTGCCT/ACAGCC`	1	--	nc-transcript-variant		1		NA	2

HapMap Linkage Disequilibrium report for HNF1A-AS1 (121406416 - 121418768 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for HNF1A-AS1: --

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for HNF1A-AS1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with HNF1A-AS1)

Utopia: connect your pdf to the dynamic
world of online information

Genome-wide association study identifies loci influenc ing concentrations of liver enzymes in plasma. (PubMed id 22001757)¹ Chambers J.C....Kooner J.S. (2011)
Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. (PubMed id 18940312)¹ Yuan X....Mooser V. (2008)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)¹ Ota T.... Sugano S. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 283460	HGNC: 26785	Ensembl:ENSG00000241388	euGenes: HUgn283460	ECgene: HNF1A-AS1
H-InvDB: HNF1A-AS1

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for HNF1A-AS1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for HNF1A-AS1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for HNF1A-AS1 gene:
Search GeneIP for patents involving HNF1A-AS1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

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HNF1A antisense RNA 1

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