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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HMSD Gene

protein-coding   GIFtS: 35
GCID: GC18P061616

Histocompatibility (Minor) Serpin Domain Containing


(Previous symbol: C18orf53)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Histocompatibility (Minor) Serpin Domain Containing1 2     ACC-62
C18orf531 2 3     Serpin-Like Protein HMSD2
Minor Histocompatibility Protein HMSD2 3     Minor Histocompatibility Serpin Domain-Containing Protein3
HSMD-v2 3     

External Ids:    HGNC: 230371   Entrez Gene: 2842932   Ensembl: ENSG000002218877   OMIM: 6120865   UniProtKB: P0C7T43   
UniProtKB: A8MTL93   

Export aliases for HMSD gene to outside databases

Previous GC identifers: GC18P059768 GC18P058317


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for HMSD Gene:
This gene encodes a serpin-domain containing protein that may function as a serine protease inhibitor. This gene
is primarily expressed in cells of myeloid lineage. A polymorphism in this gene may result in the expression a
splice variant that encodes a minor histocompatibility antigen. (provided by RefSeq, Oct 2010)

GeneCards Summary for HMSD Gene: 
HMSD (histocompatibility (minor) serpin domain containing) is a protein-coding gene. Diseases associated with HMSD include hematopoietic stem cell transplantation, and graft versus host disease. GO annotations related to this gene include serine-type endopeptidase inhibitor activity.

UniProtKB/Swiss-Prot: HMSD_HUMAN, A8MTL9
Function: Putative serine protease inhibitor (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000018.9  NC_018929.2  NT_025028.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HMSD gene promoter:
         POU3F1   FOXO3   LCR-F1   FOXO3b   FOXL1   MEF-2A   POU2F1   POU2F1a   FOXO3a   aMEF-2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for HMSD

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HMSD


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q22.1   Ensembl cytogenetic band:  18q22.1   HGNC cytogenetic band: 18q21.33

HMSD Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HMSD gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18P061616:  view genomic region     (about GC identifiers)

Start:
61,616,535 bp from pter      End:
61,649,008 bp from pter
Size:
32,474 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: HMSDV_HUMAN, P0C7T4 (See protein sequence)
Recommended Name: Minor histocompatibility protein HMSD variant form  
Size: 53 amino acids; 6023 Da
Subunit: ACC-6 forms a complex with MHC HLA-B*4403
Caution: Translation of HMSD-v form generating mHA ACC-6 is in a frame different from that resulting in HMSD non
variant form expression. Thus, the HMSD non variant form sequence does not contain the mHA ACC-6 peptide
Alternative splicing: 2 isoforms:  P0C7T4-1   A8MTL9-1   (This alternative splicing is due 1 intronic SNP)

UniProtKB/Swiss-Prot: HMSD_HUMAN, A8MTL9 (See protein sequence)

Recommended Name: Serpin-like protein HMSD precursor  
Size: 139 amino acids; 15355 Da
Subcellular location: Secreted (Potential)
Caution: Translation of HMSD-v form generating mHA ACC-6 is in a frame different from that resulting in HMSD non
variant form expression. Thus, HMSD sequence described in this entry does not contain the mHA ACC-6 peptide
Alternative splicing: 2 isoforms:  A8MTL9-1   P0C7T4-1   (This alternative splicing is due 1 intronic SNP)

Explore the universe of human proteins at neXtProt for HMSD: NX_A8MTL9

Explore proteomics data for HMSD at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_A8MTL9

  • HMSD Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    HMSD Protein Expression
    REFSEQ proteins: NP_001116838.1  
    ENSEMBL proteins: 
     ENSP00000386207   ENSP00000431632  

    Human Recombinant Protein Products for HMSD: 
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    OriGene Protein Over-expression Lysate for HMSD
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for HMSD 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region ----
    GO:0005615extracellular space IEA--

    HMSD for ontologies           About GeneDecksing



    HMSD Antibody Products: 
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    Cloud-Clone Corp. ELISAs for HMSD 
    Cloud-Clone Corp. CLIAs for HMSD


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR000215 Serpin_fam
     IPR023796 Serpin_dom

    Graphical View of Domain Structure for InterPro Entry P0C7T4
    Graphical View of Domain Structure for InterPro Entry A8MTL9

    ProtoNet protein and cluster: P0C7T4

    UniProtKB/Swiss-Prot: HMSD_HUMAN, A8MTL9
    Similarity: Belongs to the serpin family


    HMSD for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HMSDV_HUMAN, P0C7T4
    Function: This allelic splice variant of HMSD is the precursor of the histocompatibility antigen ACC-6. More
    generally, minor histocompatibility antigens (mHags) refer to immunogenic peptide which, when complexed with MHC,
    can generate an immune response after recognition by specific T-cells. The peptides are derived from polymorphic
    intracellular proteins, which are cleaved by normal pathways of antigen processing. The binding of these peptides
    to MHC class I or class II molecules and its expression on the cell surface can stimulate T-cell responses and
    thereby trigger graft rejection or graft-versus-host disease (GVHD) after hematopoietic stem cell transplantation
    from HLA-identical sibling donor. GVHD is a frequent complication after bone marrow transplantation (BMT), due to
    mismatch of minor histocompatibility antigen in HLA-matched sibling marrow transplants. However, associated with
    GVHD, a favorable graft-versus-leukemia (GVL) can be induced by donor-recipient disparities in mHags. ACC-6 is
    presented to the cell surface by MHC HLA-B*4403. This complex specifically elicits donor-cytotoxic T-lymphocyte
    (CTL) reactivity against hematologic malignancies after treatment by HLA-identical allogenic BMT. It induces cell
    recognition and lysis by CTL. Immunogenicity of most autosomal mHags results from single-nucleotide polymorphisms
    that cause amino-acid substitutions within epitopes, leading to the differential recognition of peptides between
    donor and recipient

         UniProtKB/Swiss-Prot: HMSD_HUMAN, A8MTL9
    Function: Putative serine protease inhibitor (By similarity)

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004867serine-type endopeptidase inhibitor activity IEA--
         
    HMSD for ontologies           About GeneDecksing


    Animal Models:
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    miRNA
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    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector: HMSD (NM_001123366)
    Sino Biological Human cDNA Clone for HMSD
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HMSD
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HMSD


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HMSD

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HMSD

    Search CenterWatch for drugs/clinical trials and news about HMSD

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for HMSD gene: 
    NM_001123366.1  

    Unigene Cluster for HMSD:

    Histocompatibility (minor) serpin domain containing
    Hs.721604  [show with all ESTs]
    Unigene Representative Sequence: BM910193
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000408945(uc010dqj.3) ENST00000481726 ENST00000526932 ENST00000498680

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HMSD
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate HMSD
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for HMSD
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HMSD
    Clone
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    OriGene clones in human, mouse for HMSD (see all 6)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: HMSD (NM_001123366)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HMSD
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat HMSD
    Sirion Biotech Customized lentivirus for stable overexpression of HMSD 
                         Customized lentivirus expression plasmids for stable overexpression of HMSD 
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for HMSD
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HMSD
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HMSD

    1 DOTS entry:

    DT.75174437 

    24/66 AceView cDNA sequences (see all 66):

    CB122815 BM696260 CK904586 AA972628 BC034528 AL711105 CK904587 NM_198833 
    CF130399 AA360401 NM_002640 L40377 U92984 AW205887 AL597104 BI819086 
    BM987817 BQ929418 AA373798 AL121194 BQ435307 AL708543 W61361 AI767324 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HMSD expression in normal human tissues (normalized intensities)      HMSD embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGGGCAAAGG
    HMSD Expression
    About this image


    HMSD expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/1 selected tissues (see all 1) fully expand
     
     Pancreas (Endocrine System)
             Pancreatic endoderm/endocrine precursor-like cells ( A scalable, suspension protocol...

    See HMSD Protein Expression from SPIRE MOPED and PaxDB
    SOURCE GeneReport for Unigene cluster: Hs.721604

    UniProtKB/Swiss-Prot: HMSDV_HUMAN, P0C7T4
    Tissue specificity: Highly expressed in dendritic cells and primary leukemia cells, especially those of myeloid
    lineage. ACC-6 expression is limited to cells of the hematopoietic lineage

    UniProtKB/Swiss-Prot: HMSD_HUMAN, A8MTL9
    Tissue specificity: Highly expressed in dendritic cells and primary leukemia cells, especially those of myeloid
    lineage

        SABiosciences Custom PCR Arrays for HMSD
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HMSD

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of mammals.

    Orthologs for HMSD gene from 1/2 species (see all 2)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    platypus
    (Ornithorhynchus anatinus)
    Mammalia HMSD6
    histocompatibility (minor) serpin domain containin...
    17(a)
    1 ↔ 1
    Contig23495(1397-9581)


    ENSEMBL Gene Tree for HMSD (if available)
    TreeFam Gene Tree for HMSD (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HMSD gene
    14 SIMAP similar genes for HMSD using alignment to 2 protein entries:     HMSDV_HUMAN (see all proteins):
    SERPINB6    SERPINB8    SERPINB4    SERPINA3    SERPINA1    SERPINA9
    SERPINA6    SERPINB13    SERPINB10    SERPINB7    SERPINB5    SERPINA5
    SERPINB12    SERPINB11

    HMSD for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    UniProtKB/Swiss-Prot: HMSD_HUMAN, A8MTL9
    Polymorphism: Minor histocompatibility antigen ACC-6 (mHA ACC-6) is encoded by HMSD-v which is an allelic variant
    of HMSD. HMSD-v results from an intronic single-nucleotide polymorphism located at position 5 of HMSD intron 2
    leading to a G to A substitution. This variation in intron 2 induces skipping of exon 2 and frameshift, resulting
    in expression of ACC-6
    Polymorphism: Minor histocompatibility antigen ACC-6 (mHA ACC-6) is encoded by HMSD-v which is an allelic variant
    of HMSD. HMSD-v results from an intronic single-nucleotide polymorphism located at position 5 of HMSD intron 2
    leading to a G to A substitution. This variation in intron 2 induces skipping of exon 2 and frameshift, resulting
    in expression of ACC-6


    10/295 SNPs in HMSD are shown (see all 295)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs105718381,2
    C--58318270(+) GATAG-/TATGTTT 1 -- int10--------
    rs1129066661,2
    C--58324722(+) AAAAA-/ACAAACT 1 -- int11Minor allele frequency- AC:0.50CSA 2
    rs6856621,2
    C,F--58324723(-) AGTTTT/GTTTTT 1 -- int15Minor allele frequency- G:0.33NA WA CSA 9
    rs742570461,2
    C--61470708(+) AAACTC/GTAAAA 1 -- us2k12Minor allele frequency- G:0.18CSA EA 122
    rs1911408061,2
    --61470799(+) TAAAAA/CTGGGG 1 -- us2k10--------
    rs794371921,2
    C,F--61471015(+) CAAATT/CTGATA 1 -- us2k11Minor allele frequency- C:0.04WA 118
    rs797256091,2
    C,F--61471083(+) AGGAAA/GTAGAA 1 -- us2k12Minor allele frequency- G:0.19CSA WA 120
    rs1838674641,2
    --61471104(+) GGCCTA/GTATCT 1 -- us2k10--------
    rs751428861,2
    F--61471131(+) AATAAT/ATAATA 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1406513741,2
    --61471183(+) AAATTA/CTAAAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for HMSD (61616535 - 61649008 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for HMSD:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv21739CNV Gain19812545
    nsv909693CNV Gain21882294
    nsv833673CNV Gain17160897


    Human Gene Mutation Database (HGMD): HMSD
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing HMSD
    DNA2.0 Custom Variant and Variant Library Synthesis for HMSD

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 612086    OMIM disorders: --

    3 diseases for HMSD:    About MalaCards
    hematopoietic stem cell transplantation    graft versus host disease    leukemia


    HMSD for disorders           About GeneDecksing


    Export disorders for HMSD gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HMSD gene integrated from 9 sources:
    (articles sorted by number of sources associating them with HMSD)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Alternative splicing due to an intronic SNP in HMSD generates a novel minor histocompatibility antigen. (PubMed id 17409267)1, 2, 3 Kawase T.... Takahashi T. (2007)
    2. DNA sequence and analysis of human chromosome 18. (PubMed id 16177791)1, 2 Nusbaum C.... Lander E.S. (2005)
    3. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1, 2 Bonaldo M.F.... Soares M.B. (1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 284293 HGNC: 23037 AceView: SERPINB8 Ensembl:ENSG00000221887 euGenes: HUgn284293
    ECgene: HMSD H-InvDB: HMSD

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HMSD Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for HMSD gene:
    Search GeneIP for patents involving HMSD

    GeneCards and IP:
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