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Aliases for HMP19 Gene

Aliases for HMP19 Gene

  • HMP19 Protein 3
  • Protein P19 3 4
  • NSG2 3 4
  • Hypothalamus Golgi Apparatus Expressed 19 KDa Protein 3
  • Neuron-Specific Protein Family Member 2 3
  • P19 Protein 3
  • Hmp19 4

External Ids for HMP19 Gene

Previous GeneCards Identifiers for HMP19 Gene

  • GC05P173730
  • GC05P174174
  • GC05P173408
  • GC05P173453
  • GC05P173405
  • GC05P168568

Summaries for HMP19 Gene

GeneCards Summary for HMP19 Gene

HMP19 (HMP19 Protein) is a Protein Coding gene. GO annotations related to this gene include clathrin light chain binding. An important paralog of this gene is NSG1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HMP19 Gene

Genomics for HMP19 Gene

Regulatory Elements for HMP19 Gene

Genomic Location for HMP19 Gene

174,045,604 bp from pter
174,243,501 bp from pter
197,898 bases
Plus strand

Genomic View for HMP19 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for HMP19 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HMP19 Gene

Proteins for HMP19 Gene

  • Protein details for HMP19 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Neuron-specific protein family member 2
    Protein Accession:
    Secondary Accessions:
    • B2R5Y0
    • D3DQN0
    • Q9UHX8

    Protein attributes for HMP19 Gene

    171 amino acids
    Molecular mass:
    19085 Da
    Quaternary structure:
    No Data Available

neXtProt entry for HMP19 Gene

Proteomics data for HMP19 Gene at MOPED

Post-translational modifications for HMP19 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for HMP19 Gene

No data available for DME Specific Peptides for HMP19 Gene

Domains for HMP19 Gene

Protein Domains for HMP19 Gene

Suggested Antigen Peptide Sequences for HMP19 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q9Y328
  • Belongs to the NSG family.
genes like me logo Genes that share domains with HMP19: view

No data available for Gene Families for HMP19 Gene

Function for HMP19 Gene

Gene Ontology (GO) - Molecular Function for HMP19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0032051 clathrin light chain binding IEA --
genes like me logo Genes that share ontologies with HMP19: view

Phenotypes for HMP19 Gene

genes like me logo Genes that share phenotypes with HMP19: view

Animal Model Products

CRISPR Products

miRNA for HMP19 Gene

miRTarBase miRNAs that target HMP19

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for HMP19

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for HMP19 Gene

Localization for HMP19 Gene

Subcellular locations from UniProtKB/Swiss-Prot for HMP19 Gene

Cytoplasmic vesicle membrane; Single-pass type II membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Endosome, multivesicular body membrane; Single-pass type II membrane protein. Note=Mainly Golgi stack, but also found in small vacuolar organelles and multivesicular bodies. {ECO:0000250}.

Subcellular locations from

Jensen Localization Image for HMP19 Gene COMPARTMENTS Subcellular localization image for HMP19 gene
Compartment Confidence
endosome 5
golgi apparatus 5
cytosol 2
extracellular 2
peroxisome 2
endoplasmic reticulum 1
mitochondrion 1
nucleus 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for HMP19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005768 endosome --
GO:0005794 Golgi apparatus --
GO:0016021 integral component of membrane IEA --
GO:0030659 cytoplasmic vesicle membrane IEA --
GO:0031410 cytoplasmic vesicle --
genes like me logo Genes that share ontologies with HMP19: view

Pathways for HMP19 Gene

SuperPathways for HMP19 Gene

No Data Available

Gene Ontology (GO) - Biological Process for HMP19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007212 dopamine receptor signaling pathway IEA --
GO:0048268 clathrin coat assembly IEA --
genes like me logo Genes that share ontologies with HMP19: view

No data available for Pathways by source for HMP19 Gene

Transcripts for HMP19 Gene

Unigene Clusters for HMP19 Gene

HMP19 protein:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for HMP19

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for HMP19 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b · 5c
SP1: -
SP3: -

Relevant External Links for HMP19 Gene

GeneLoc Exon Structure for

Expression for HMP19 Gene

mRNA expression in normal human tissues for HMP19 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for HMP19 Gene

This gene is overexpressed in Brain - Nucleus accumbens (basal ganglia) (8.8), Brain - Putamen (basal ganglia) (6.8), Brain - Caudate (basal ganglia) (6.6), Brain - Hypothalamus (4.5), and Brain - Anterior cingulate cortex (BA24) (4.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for HMP19 Gene

SOURCE GeneReport for Unigene cluster for HMP19 Gene Hs.559412

genes like me logo Genes that share expressions with HMP19: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for HMP19 Gene

Orthologs for HMP19 Gene

This gene was present in the common ancestor of chordates.

Orthologs for HMP19 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 36
  • 100 (a)
LOC462279 35
  • 100 (n)
  • 100 (a)
(Bos Taurus)
Mammalia HMP19 35
  • 93.76 (n)
  • 98.83 (a)
NSG2 36
  • 99 (a)
(Canis familiaris)
Mammalia -- 36
  • 100 (a)
HMP19 35
  • 94.35 (n)
  • 100 (a)
(Mus musculus)
Mammalia Nsg2 35
  • 91.03 (n)
  • 97.08 (a)
Nsg2 16
Nsg2 36
  • 97 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 78 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 70 (a)
(Rattus norvegicus)
Mammalia Nsg2 35
  • 90.64 (n)
  • 96.49 (a)
(Gallus gallus)
Aves -- 36
  • 78 (a)
LOC416212 35
  • 76.22 (n)
  • 83.04 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 76 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia hmp19 35
  • 73.92 (n)
  • 80 (a)
(Danio rerio)
Actinopterygii hmp19 35
  • 72.9 (n)
  • 72.51 (a)
hmp19 36
  • 68 (a)
zgc73142 35
Species with no ortholog for HMP19:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for HMP19 Gene

Gene Tree for HMP19 (if available)
Gene Tree for HMP19 (if available)

Paralogs for HMP19 Gene

Paralogs for HMP19 Gene

Selected SIMAP similar genes for HMP19 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with HMP19: view

Variants for HMP19 Gene

Sequence variations from dbSNP and Humsavar for HMP19 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs889076 -- 174,109,636(-) CTAAG(C/T)CCTAA downstream-variant-500B
rs1048907 -- 174,109,106(+) TAGCA(A/G)AGGCG utr-variant-3-prime
rs1235134 -- 174,062,548(-) TTCCT(C/T)AAACA intron-variant
rs1385310 -- 174,088,319(-) ACAGA(A/C/T)GGACT intron-variant
rs2077887 -- 174,057,534(-) CCTAC(A/G)AAGTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for HMP19 Gene

Variant ID Type Subtype PubMed ID
dgv113n17 CNV Loss 16327808
esv2731129 CNV Deletion 23290073
esv990876 CNV Deletion 20482838
esv2731130 CNV Deletion 23290073
esv1477078 CNV Deletion 17803354
nsv5137 CNV Loss 18451855
esv2731131 CNV Deletion 23290073

Relevant External Links for HMP19 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HMP19 Gene

Disorders for HMP19 Gene

Relevant External Links for HMP19

Genetic Association Database (GAD)
genes like me logo Genes that share disorders with HMP19: view

No data available for UniProtKB/Swiss-Prot for HMP19 Gene

Publications for HMP19 Gene

  1. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PMID: 10931946) Hu R.-M. … Chen J.-L. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3
  4. A directed protein interaction network for investigating intracellular signal transduction. (PMID: 21900206) Vinayagam A. … Wanker E.E. (Sci Signal 2011) 3
  5. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PMID: 22589738) Fox C.S. … Borecki I.B. (PLoS Genet. 2012) 3

Products for HMP19 Gene

Sources for HMP19 Gene

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