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HMMR Gene

protein-coding GIFtS: 57

GC05P162820

hyaluronan-mediated motility receptor (RHAMM)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
CD168 ^¹, ²
IHABP ^², ³
MGC119494 ^²
MGC119495 ^²
RHAMM ^¹, ², ³

Descriptions
CD168 antigen ^³
Intracellular hyaluronic acid-binding protein ^³
Receptor for hyaluronan-mediated motility ^³
hyaluronan-mediated motility receptor ^²
hyaluronan-mediated motility receptor (RHAMM) ^²
intracellular hyaluronic acid binding protein ^²

External Ids
HGNC: 5012¹
Entrez Gene: 3161²
UniProtKB: O75330³
Ensembl: ENSG00000072571⁷

Search outside databases for aliases for HMMR gene

Previous GC identifers: GC05P163090 GC05P163480 GC05P162822 GC05P162868

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for HMMR:

The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and

together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially

associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding

different isoforms have been noted for this gene. [provided by RefSeq]

UniProtKB/Swiss-Prot: HMMR_HUMAN, O75330

Function: Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number

of proteins, including the focal adhesion kinase occurs. May also be involved in cellular

transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK)

activity

Gene Wiki entry for HMMR (Hyaluronan-mediated_motility_receptor)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the HMMR gene

Entrez Gene cytogenetic band: 5q33.2-qter Ensembl cytogenetic band: 5q34 HGNC cytogenetic band: 5q33.2-qter

HMMR Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 5 GeneLoc Exon Structure

GeneLoc location for GC05P162820: (about GC identifiers)

Start:	162,820,241 bp from pter
End:	162,851,525 bp from pter
Size:	31,285 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000005.8 NT_023133.12

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: HMMR_HUMAN, O75330 (See protein sequence)

Recommended Name: Hyaluronan mediated motility receptor

Size: 724 amino acids; 84100 Da

Subunit: Subunit of the HARC complex

Subcellular location: Cell surface. Cytoplasm (By similarity)

Secondary accessions: Q92767

Alternative splicing: 2 isoforms: O75330-1 O75330-2

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (4 alternative transcripts):

NP_001136028.1 NP_001136029.1 NP_036616.2 NP_036617.2

ENSEMBL proteins:

ENSP00000377492 ENSP00000185942 ENSP00000351554

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (CD168)
	Browse Abnova for Human Recombinant Proteins

OriGene Purified Recombinant Human Proteins (see all 2): HMMR

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--
GO:0009986	cell surface	IEA	--

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Antibodies for HMMR:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse Antibodies at Sigma-Aldrich
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (CD168), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for HMMR

Assays for HMMR:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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ProtoNet protein and cluster: O75330

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (HMMR)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4): NM_012484

Applied Biosystems Silencer® siRNAs for HMMR

Sigma-Aldrich siRNA for HMMR

Sigma-Aldrich shRNA Panels and shRNA for HMMR

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 4): NM_001142556
Myc/DDK tagged cDNA clones in CMV expression vector (see all 4): NM_001142556
untagged cDNA clones in CMV expression vector (see all 4): NM_001142556

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001142556

UniProtKB/Swiss-Prot: HMMR_HUMAN, O75330

Function: Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number

of proteins, including the focal adhesion kinase occurs. May also be involved in cellular

transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK)

activity

Genatlas biochemistry entry for HMMR:

hyaluronan-mediated motility receptor,involved in signal transduction via Src tyrosine kinase

family,expressed in the cytoplasm,nucleus,and cell surface,five isoforms

(58,60,64,70,84kDa),regulating cell motility and cell cycle

2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Hmmr):

reproductive system

tumorigenesis

1 Gene Ontology (GO) molecular function term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005540	hyaluronic acid binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for HMMR

5/16 Interacting proteins for HMMR (ENSP00000351554³) via UniProtKB, MINT, and/or STRING (see all 16 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CD44	ENSP00000278385³	STRING (score=.966)
CALM3	ENSP00000291295³	STRING (score=.939)
TP53	ENSP00000269305³	STRING (score=.895)
AR	ENSP00000363822³	STRING (score=.888)
CD40LG	ENSP00000359663³	STRING (score=.842)

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for HMMR
2 Novoseek chemical compound relationships for HMMR gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
chondroitin sulfate	22.04	1	9601098 (1)
tyrosine	10.02	5	8750188 (2), 12793201 (1), 1380898 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (HMMR)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4): NM_012484

Sigma-Aldrich siRNA for HMMR

Sigma-Aldrich shRNA Panels and shRNA for HMMR

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001142556 NM_001142557 NM_012484 NM_012485

REFSEQ mRNAs for HMMR gene (4 alternative transcripts):

NM_001142556.1 NM_001142557.1 NM_012484.2 NM_012485.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001142556 NM_001142557 NM_012484 NM_012485

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 4): NM_001142556
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 4): NM_001142556
                                 untagged cDNA clones in CMV expression vector (see all 4): NM_001142556

Additional cDNA sequence:

AF032862.1 AK290577.1 AK302975.1 AK303616.1 AK313603.1 AY623426.1 BC002966.1 BC017793.1

BC030505.2 BC033568.1 BC057235.1 BC070281.1 BC107869.1 BC108904.1 BC108905.1 CR592683.1

CR601287.1 U29343.1

13 DOTS entries:

DT.91706417 DT.100791432 DT.99969051 DT.91749528 DT.95271259 DT.100714653 DT.92022397 DT.75169576

DT.120888710 DT.100791427 DT.92019707 DT.92023184 DT.91789912

24/172 AceView cDNA sequences (see all 172 ):

BE327167 AI209041 CB132559 AF032862 AW057729 BM788751 BQ027031 CR601287

AA743743 BM725946 BQ010466 BE042983 BM764295 BE892436 BM772368 AA831946

AA553484 AA262978 AA687269 CA443399 NM_012485 AI088336 BM849217 BM680960

highest scoring ESTs for HMMR:

AF032862 AA164270 AA262978 AA410932 AA460915 AA461217 AA593010 AA612782 AA632211 AA687269

Unigene Cluster for HMMR:

Hyaluronan-mediated motility receptor (RHAMM)

Hs.72550 [show with all ESTs]

Unigene Representative Sequence: NM_001142556

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for HMMR (see all 6 )

ExUns:	1	^	2a	·	2b	^	3	^	4a	·	4b	^	5	^	6	^	7	^	8a	·	8b	^	9	^	10	^	11	^	12	^	13	^	14	^	15	^	16	^	17a	·	17b	^	18a	·	18b	^	19
SP1:											-
SP2:											-
SP3:											-		-
SP4:			-		-						-		-
SP5:

About this scheme

ECgene alternative splicing isoforms for HMMR

3 Ensembl transcripts including schematic representations:

ENST00000393915 ENST00000353866 ENST00000358715

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

HMMR expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for HMMR

¹ / ² / ³

5 probe-sets matching HMMR gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
36863_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	AF032862	1.00	1.00	1.00	1
207165_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_012485	0.60	1.00	0.82	1
209709_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	U29343	0.80	1.00	0.91	1
207165_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
209709_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks HMMR for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TCTACTCAGC

SOURCE GeneReport for Unigene cluster: Hs.72550
Expression variation in blood from EXPOLDB for HMMR
UniProtKB/Swiss-Prot: HMMR_HUMAN, O75330
Tissue specificity: Expressed in breast cancer cell lines and in normal breast tissue

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for HMMR gene from 5/8 species (see all 8 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	HMMR¹	--	hyaluronan-mediated motility receptor (RHAMM)	87.88(n) 86.7(a)	611838 XM_849558.1 XP_854651.1
chimpanzee (Pan troglodytes)	HMMR¹	--	hyaluronan-mediated motility receptor (RHAMM)	99.13(n) 98.34(a)	737973 XM_001145921.1 XP_001145921.1
cow (Bos taurus)	HMMR¹	--	hyaluronan-mediated motility receptor (RHAMM)	87.02(n) 82.51(a)	281227 XM_590028.3 XP_590028.3
rat (Rattus norvegicus)	Hmmr¹	--	hyaluronan mediated motility receptor (RHAMM)	78.72(n) 75.39(a)	25460 NM_012964.2 NP_037096.2
mouse (Mus musculus)	Hmmr^{1, 5}	11 (19.00 cM)⁵	hyaluronan mediated motility receptor (RHAMM)^{1, 5}	70.29(n)¹ 63.84(a)¹	15366¹ NM_013552.1¹ NP_038580.1¹ AF031932⁵ AF079222⁵ (see all 20)

About this table Species with no ortholog for HMMR

ENSEMBL Gene Tree for HMMR

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/132 NCBI SNPs in HMMR are shown (see all 132 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 92)

AB	SNP ID	Valid	Chr 5 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs299295^1,2	A,C,F,H,O	162842294(+)	`AAAAGC/TGGCCA`	4	A/V	mis¹ ese³		16	NA EA MN EU WA	1478
	rs6890805^1,2	A,C,F,H	162850757(+)	`TCTGAG/AAAACC`	4	--	ut3¹ ese³		7	EU EA WA NA	562
	rs2303078^1,2	C,F,H,O	162833734(+)	`GGAACG/ATGAAA`	4	H/R	mis¹		12	NA EU EA WA	1056
	rs299284^1,2	C,F,H,O	162829228(+)	`AGATTC/TGTGTT`	4	R/C	mis¹		14	EU EA WA NA	1122
	rs2230363^1,2	C,F,H	162843653(+)	`TTCAGC/ATACAA`	4	I/L	mis¹		13	MN NA EU EA WA	1086
	rs299290^1,2	C,F,H	162835094(+)	`AATGGC/TTAAAG`	4	V/A	mis¹ ese³		19	MN EA NA EU WA	2834
	rs2230362^1,2	C,F,H	162842743(+)	`TGGAAG/CATGAA`	4	H/D	mis¹		9	MN EU EA WA	886
	rs2303077^1,2	C,F,H	162833699(+)	`CAAAAC/GTTAAA`	4	N/K	mis¹		8	EU EA WA	804
	rs11960695^1,2	F,H	162851844(+)	`AGAAAC/TGTAGA`	2	--	ng3¹		4	EU EA WA	416
	rs17600938^1,2	C,F,H	162842265(+)	`CTTAAG/ACTGGA`	4	K/K	syn¹		7	NA EU EA WA	562

About this table

HapMap Linkage Disequilibrium images for HMMR (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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OMIM: 600936 disorders: 114480

10/15 Novoseek disease relationships for HMMR gene (see all 15 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
fibrosarcoma	37.89	2	8750188 (1), 7541721 (1)
leukemia hairy cell	37.18	4	7678518 (2), 7529076 (1)
metastasis	29.36	14	9533523 (3), 18174258 (2), 11029494 (1), 12469144 (1) (see all 9)
myeloma	29.06	2	15705883 (1), 7529076 (1)
myxoma	27.63	2	1710472 (1), 2035257 (1)
tumors	24.27	28	11029494 (4), 18971636 (2), 9533523 (2), 11716065 (1) (see all 17)
cancer	13.24	13	18174258 (2), 11029494 (1), 12469144 (1), 15705883 (1) (see all 9)
breast carcinoma	10.65	3	8750188 (1), 9601098 (1), 9533523 (1)
primary tumor	5.98	3	9533523 (3)
breast cancer	5.57	15	9533523 (4), 17392272 (3), 19064580 (2), 9601098 (1)

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Human Genome Epidemiology Navigator: HMMR (1 document)

(Possibly Related Articles in Doctor's Guide)
About This Section

Researchers Find New Gene Linked to Breast Cancer

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/129 PubMed articles for HMMR gene (see all 129 ):

The human hyaluronan receptor RHAMM is expressed as an intracellular protein in breast cancer cells. (PubMed id 9601098)^{1, 3, 4} Assmann V.... Hart I.R. (1998)
Phosphoproteome analysis of the human mitotic spindle. (PubMed id 16565220)^{3, 4} Nousiainen M.... Koerner R. (2006)
The characterization of a human RHAMM cDNA: conservation of the hyaluronan-binding domains. (PubMed id 8890751)^{3, 4} Wang C.... Turley E.A. (1996)
RHAMM is differentially expressed in the cell cycle and downregulated by the tumor suppressor p53. (PubMed id 18971636)^{1, 3} Sohr S. and Engeland K. (2008)
Regulated expression of a receptor for hyaluronan-mediated motility on human thymocytes and T cells. (PubMed id 7683315)^{1, 3} Pilarski L.M....Turley E.A. (1993)
The hyaluronan receptors CD44 and Rhamm (CD168) form complexes with ERK1,2 that sustain high basal motility in breast cancer cells. (PubMed id 17392272)^{1, 3} Hamilton S.R....Turley E.A. (2007)
Receptor for hyaluronan-mediated motility correlates with centrosome abnormalities in multiple myeloma and maintains mitotic integrity. (PubMed id 15705883)^{1, 3} Maxwell C.A....Reiman T. (2005)
The human and mouse receptors for hyaluronan-mediated motility, RHAMM, genes (HMMR) map to human chromosome 5q33.2-qter and mouse chromosome 11. (PubMed id 8595891)^{1, 3} Spicer A.P....McDonald J.A. (1995)
The candidate immunotherapeutical target, the receptor for hyaluronic acid-mediated motility, is associated with proliferation and shows prognostic value in B-cell chronic lymphocytic leukemia. (PubMed id 19092852)^{1, 3} Giannopoulos K....Schmitt M. (2009)
Androgen receptor regulates CD168 expression and signaling in prostate cancer. (PubMed id 18174258)^{1, 3} Lin S.L....Ying S.Y. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 3161	HGNC: 5012	AceView: HMMR	Ensembl:ENSG00000072571	euGenes: HUgn3161
ECgene: HMMR	H-InvDB: HMMR

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
ATLAS Chromosomes in Cancer entry for HMMR	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for HMMR
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for HMMR:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for HMMR-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for HMMR		Browse antibodies at Sigma-Aldrich
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for HMMR		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

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	Cell Culture Products		ELISAs
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Search Tocris compounds for HMMR

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HMMR Gene

protein-coding GIFtS: 57

Aliases &
Descriptions
for HMMR

Summaries
for HMMR

Genomic Location
for HMMR

Proteins
for HMMR

Protein Domains/
Families
for HMMR

Gene Function
for HMMR

Pathways & Interactions
for HMMR

Drugs & Compounds
for HMMR

Transcripts
for HMMR

Expression
for HMMR

Orthologs
for HMMR

Paralogs
for HMMR

SNPs/Variants
for HMMR

Disorders & Mutations
for HMMR

Medical News
for HMMR

Publications
for HMMR

Search for HMMR

Genome Databases showing HMMR

Other Databases showing HMMR

Specialized Databases showing HMMR

Licensable Technologies
for HMMR

Services
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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

HMMR Gene

protein-coding GIFtS: 57

Aliases & Descriptionsfor HMMR

Summariesfor HMMR

Genomic Locationfor HMMR

Proteinsfor HMMR

Protein Domains/Familiesfor HMMR

Gene Functionfor HMMR

Pathways & Interactionsfor HMMR

Drugs & Compoundsfor HMMR

Transcriptsfor HMMR

Expression for HMMR

Orthologsfor HMMR

Paralogsfor HMMR

SNPs/Variantsfor HMMR

Disorders & Mutationsfor HMMR

Medical Newsfor HMMR

Publicationsfor HMMR

Search for HMMR

Genome Databases showing HMMR

Other Databases showing HMMR

Specialized Databases showing HMMR

Licensable Technologiesfor HMMR

Servicesfor HMMR

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for HMMR

Summaries
for HMMR

Genomic Location
for HMMR

Proteins
for HMMR

Protein Domains/
Families
for HMMR

Gene Function
for HMMR

Pathways & Interactions
for HMMR

Drugs & Compounds
for HMMR

Transcripts
for HMMR

Expression
for HMMR

Orthologs
for HMMR

Paralogs
for HMMR

SNPs/Variants
for HMMR

Disorders & Mutations
for HMMR

Medical News
for HMMR

Publications
for HMMR

Licensable Technologies
for HMMR

Services
for HMMR