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HMGN5 Gene

protein-coding   GIFtS: 46
GCID: GC0XM080370

High Mobility Group Nucleosome Binding Domain 5

(Previous names: nucleosomal binding protein 1, high-mobility group nucleosome...)
(Previous symbol: NSBP1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
High Mobility Group Nucleosome Binding Domain 51 2     Nucleosome-Binding Protein 12 3
NSBP11 2 3 5     NBP-452
High-Mobility Group Nucleosome Binding Domain 51 2     High Mobility Group Nucleosome-Binding Domain-Containing Protein 52
Nucleosomal Binding Protein 11 2     

External Ids:    HGNC: 80131   Entrez Gene: 793662   Ensembl: ENSG000001981577   OMIM: 3003855   UniProtKB: P829703   

Export aliases for HMGN5 gene to outside databases

Previous GC identifers: GC0XM080255 GC0XM073949


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for HMGN5 Gene:
This gene encodes a nuclear protein with similarities to the high mobility group proteins, HMG14 and HMG17, which
suggests that this protein may function as a nucleosomal binding and transcriptional activating protein.
(provided by RefSeq, Sep 2009)

GeneCards Summary for HMGN5 Gene:
HMGN5 (high mobility group nucleosome binding domain 5) is a protein-coding gene. Diseases associated with HMGN5 include clear cell renal cell carcinoma, and renal cell carcinoma. GO annotations related to this gene include chromatin binding and nucleosomal DNA binding.

UniProtKB/Swiss-Prot: HMGN5_HUMAN, P82970
Function: Preferentially binds to euchromatin and modulates cellular transcription by counteracting linker
histone-mediated chromatin compaction (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000023.11  NT_011651.18  NC_018934.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for HMGN5
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHMGN5 promoter sequence
   Search Chromatin IP Primers for HMGN5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HMGN5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq13.3   Ensembl cytogenetic band:  Xq21.1   HGNC cytogenetic band: Xq13.3

HMGN5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HMGN5 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM080370:  view genomic region     (about GC identifiers)

Start:
80,369,200 bp from pter      End:
80,457,441 bp from pter
Size:
88,242 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: HMGN5_HUMAN, P82970 (See protein sequence)
Recommended Name: High mobility group nucleosome-binding domain-containing protein 5  
Size: 282 amino acids; 31525 Da
Sequence caution: Sequence=AK094058; Type=Frameshift; Positions=132;
Secondary accessions: Q5JSL1

Explore the universe of human proteins at neXtProt for HMGN5: NX_P82970

Explore proteomics data for HMGN5 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See HMGN5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_110390.1  
    ENSEMBL proteins: 
     ENSP00000350848   ENSP00000408060   ENSP00000362347   ENSP00000399626   ENSP00000413402  
     ENSP00000404810  

    HMGN5 Human Recombinant Protein Products:

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    Novus Biologicals HMGN5 Proteins
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    Cloud-Clone Corp. Proteins for HMGN5

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    HMGN5 Assay Products:

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    Cloud-Clone Corp. ELISAs for HMGN5
    Cloud-Clone Corp. CLIAs for HMGN5


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    HMG: High-mobility group / Canonical

    1 InterPro protein domain:
     IPR000079 HMGN_fam

    Graphical View of Domain Structure for InterPro Entry P82970

    ProtoNet protein and cluster: P82970

    1 Blocks protein domain: IPB000079 High mobility group protein HMG14 and HMG17

    UniProtKB/Swiss-Prot: HMGN5_HUMAN, P82970
    Domain: Specifically targeted by its C-terminus to nucleosomes in euchromatin (By similarity)
    Similarity: Belongs to the HMGN family


    HMGN5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HMGN5_HUMAN, P82970
    Function: Preferentially binds to euchromatin and modulates cellular transcription by counteracting linker
    histone-mediated chromatin compaction (By similarity)

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003682chromatin binding NAS11161810
    GO:0031492nucleosomal DNA binding IEA--
    GO:0044822poly(A) RNA binding IDA--
         
    HMGN5 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Hmgn5):
     no phenotypic analysis 

    HMGN5 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Hmgn5tm1Mbus for HMGN5

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HMGN5
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for HMGN5

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HMGN5
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HMGN5

    miRNA
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    miRTarBase miRNAs that target HMGN5:
    hsa-mir-26b-5p (MIRT029263)

    Block miRNA regulation of human, mouse, rat HMGN5 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HMGN5 (see all 26):
    hsa-miR-142-5p hsa-miR-605 hsa-miR-938 hsa-miR-3133 hsa-miR-340 hsa-miR-548a-3p hsa-miR-3161 hsa-miR-3122
    SwitchGear 3'UTR luciferase reporter plasmidHMGN5 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat HMGN5

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    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HMGN5

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HMGN5


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    HMGN5_HUMAN, P82970: Nucleus. Note=Associates with nucleosomes in euchromatin and is largely excluded from
    constitutive heterochromatin (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol1
    extracellular1
    mitochondrion1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000785chromatin IEA--
    GO:0005634nucleus NAS11161810
    GO:0005654nucleoplasm IEA--
    GO:0005730nucleolus IDA--
    GO:0043231intracellular membrane-bounded organelle IDA--

    HMGN5 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HMGN5
    Interactions:

        Search GeneGlobe Interaction Network for HMGN5

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for HMGN5 (ENSP000003508484) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CBX8ENSP000002693854STRING: ENSP00000269385
    SUMO2ENSP000004059654STRING: ENSP00000405965
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated NAS11161810
    GO:0006357regulation of transcription from RNA polymerase II promoter IEA--
    GO:0016568chromatin modification IEA--
    GO:0045893positive regulation of transcription, DNA-templated NAS11161810

    HMGN5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HMGN5



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for HMGN5 gene: 
    NM_030763.2  

    Unigene Cluster for HMGN5:

    High mobility group nucleosome binding domain 5
    Hs.282204  [show with all ESTs]
    Unigene Representative Sequence: NM_030763
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000358130(uc004eee.1) ENST00000447319 ENST00000373250 ENST00000430960
    ENST00000491275 ENST00000436386 ENST00000451455
    miRNA
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    Block miRNA regulation of human, mouse, rat HMGN5 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HMGN5 (see all 26):
    hsa-miR-142-5p hsa-miR-605 hsa-miR-938 hsa-miR-3133 hsa-miR-340 hsa-miR-548a-3p hsa-miR-3161 hsa-miR-3122
    SwitchGear 3'UTR luciferase reporter plasmidHMGN5 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat HMGN5
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    GenScript: all cDNA clones in your preferred vector: HMGN5 (NM_030763)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HMGN5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HMGN5
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for HMGN5
    OriGene qSTAR qPCR primer pairs in human, mouse for HMGN5
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat HMGN5
      QuantiTect SYBR Green Assays in human, mouse, rat HMGN5
      QuantiFast Probe-based Assays in human, mouse, rat HMGN5

    Additional mRNA sequence: 

    AF250329.1 AK094058.1 AK315792.1 BC005342.1 

    10 DOTS entries:

    DT.80101740  DT.99956343  DT.40122685  DT.95157733  DT.95210672  DT.97842370  DT.91749233  DT.95157739 
    DT.100751758  DT.95157735 

    Selected AceView cDNA sequences (see all 62):

    BM977068 NM_030763 BM761606 BQ432332 AW269166 BQ440464 BQ232754 AF250329 
    BX280399 CR602524 AA669885 BG541827 BQ432883 BX348667 BQ438410 AK094058 
    CB160129 AX748432 CA942534 CD642349 BQ429736 BQ438411 BP369740 BP371008 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HMGN5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAATGTTAAG
    HMGN5 Expression
    About this image

    HMGN5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HMGN5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.282204

    UniProtKB/Swiss-Prot: HMGN5_HUMAN, P82970
    Tissue specificity: Ubiquitously expressed

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HMGN5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for HMGN5 gene from Selected species (see all 5)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hmgn55 high-mobility group nucleosome binding domain 5   --   X (47.92 cM) 109004534 
    zebrafish
    (Danio rerio)
    Actinopterygii 570687682   -- 72.16(n)    57068768 


    ENSEMBL Gene Tree for HMGN5 (if available)
    TreeFam Gene Tree for HMGN5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HMGN5 gene
    2 SIMAP similar genes for HMGN5 using alignment to 6 protein entries:     HMGN5_HUMAN (see all proteins):
    HMGN1    HMGN3

    HMGN5 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HMGN5 (see all 1062)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs23370021,2
    C,F,A,H--80340674(-) taattC/Gtatgc 1 -- ds500123Minor allele frequency- G:0.37NS EA NA WA 2537
    rs1836760441,2
    --80340738(+) GGATCA/GCTGCA 1 -- ds50010--------
    rs1888945861,2
    --80340773(+) AAGGCA/GGGAAC 1 -- ds50010--------
    rs19372921,2
    C--80340784(-) gtctaG/Agatgg 1 -- ds50012Minor allele frequency- A:0.00NA 4
    rs736317181,2
    C,F--80340867(+) GATCAC/TTTAGG 1 -- ds50011Minor allele frequency- T:0.00WA 2
    rs19372911,2
    C--80340886(-) ttttaG/Agttaa 1 -- ds50011Minor allele frequency- A:0.00NA 2
    rs19372901,2
    C--80341046(-) cAGCAG/AGTCTC 1 -- ds50012Minor allele frequency- A:0.00NA 4
    rs1996721931,2
    --80341226(+) GGGGG-/ATAAGT 1 -- ut310--------
    rs1482287551,2
    --80341229(+) GGATAA/CGTTGG 1 -- ut310--------
    rs681837771,2
    C--80341564(+) TCAAA-/ACTGCC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for HMGN5 (80369200 - 80457441 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for HMGN5:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2671958CNV Deletion23128226
    esv271671CNV Insertion20981092
    esv24043CNV Loss19812545
    esv33127CNV Loss17666407

    Locus Specific Mutation Databases (LSDB): HMGN5

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing HMGN5
    DNA2.0 Custom Variant and Variant Library Synthesis for HMGN5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 300385    OMIM disorders: --

    5 diseases for HMGN5:    
    About MalaCards
    clear cell renal cell carcinoma    renal cell carcinoma    prostate cancer    prostatitis
    lung cancer


    HMGN5 for disorders           About GeneDecksing


    Export disorders for HMGN5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HMGN5 gene, integrated from 10 sources (see all 28):
    (articles sorted by number of sources associating them with HMGN5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of a human gene encoding nucleosomal binding protein NSBP1. (PubMed id 11161810)1, 2, 3 King L.M. and Francomano C.A. (Genomics 2001)
    2. The interaction of NSBP1/HMGN5 with nucleosomes in euchromatin counteracts linker histone-mediated chromatin compaction and modulates transcription. (PubMed id 19748358)1, 3 Rochman M....Bustin M. (Mol. Cell 2009)
    3. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (Nat. Biotechnol. 2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. High mobility group protein N5 (HMGN5) and lamina-associated polypeptide 2I+ (LAP2I+) interact and reciprocally affect their genome-wide chromatin organization. (PubMed id 23673662)1 Zhang S....Bustin M. (J. Biol. Chem. 2013)
    7. Small interfering RNA targeting HMGN5 induces apoptosis via modulation of a mitochondrial pathway and Bcl-2 family proteins in prostate cancer cells. (PubMed id 22504871)1 Zhang X.Y....Zhou L.Q. (Asian J. Androl. 2012)
    8. Knockdown of HMGN5 expression by RNA interference induces cell cycle arrest in human lung cancer cells. (PubMed id 22994738)1 Chen P....Yang J.L. (Asian Pac. J. Cancer Prev. 2012)
    9. Knockdown of the nucleosome binding protein 1 inhibits the growth and invasion of clear cell renal cell carcinoma cells in vitro and in vivo. (PubMed id 22420896)1 Ji S.Q....Zhou L.Q. (amp 2012)
    10. Distinct properties of human HMGN5 reveal a rapidly evolving but functionally conserved nucleosome binding protein. (PubMed id 21518955)1 Malicet C....Bustin M. (Mol. Cell. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79366 HGNC: 8013 AceView: NSBP1 Ensembl:ENSG00000198157 euGenes: HUgn79366
    ECgene: HMGN5 H-InvDB: HMGN5

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HMGN5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for HMGN5 gene:
    Search GeneIP for patents involving HMGN5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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