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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HMGN4 Gene

protein-coding   GIFtS: 49
GCID: GC06P026538

High Mobility Group Nucleosomal Binding Domain 4

(Previous name: high-mobility group (nonhistone chromosomal) protein 17-like...)
(Previous symbol: HMG17L3)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
High Mobility Group Nucleosomal Binding Domain 41 2     High Mobility Group Nucleosome-Binding Domain-Containing Protein 42
HMG17L31 2 3     High Mobility Group Protein N42
High-Mobility Group (Nonhistone Chromosomal) Protein 17-Like 31 2     High-Mobility Group Protein 17-Like 32
Non-Histone Chromosomal Protein HMG-17-Like 32 3     Non-Histone Chromosomal Protein3
NHC2 3     

External Ids:    HGNC: 49891   Entrez Gene: 104732   Ensembl: ENSG000001829527   UniProtKB: O004793   

Export aliases for HMGN4 gene to outside databases

Previous GC identifers: GC06P026602 GC06P026646 GC06P026481


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for HMGN4 Gene:
The protein encoded by this gene, a member of the HMGN protein family, is thought to reduce the compactness of the
chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. (provided by RefSeq,
Mar 2013)

GeneCards Summary for HMGN4 Gene: 
HMGN4 (high mobility group nucleosomal binding domain 4) is a protein-coding gene. Diseases associated with HMGN4 include hypophosphatasia, and hemochromatosis. GO annotations related to this gene include nucleosomal DNA binding. An important paralog of this gene is HMGN2.

Gene Wiki entry for HMGN4 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.2  NT_007592.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HMGN4 gene promoter:
         STAT1   STAT4   STAT2   STAT3   STAT1beta   STAT5A   HNF-3beta   STAT1alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHMGN4 promoter sequence
   Search SABiosciences Chromatin IP Primers for HMGN4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HMGN4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p22.2   HGNC cytogenetic band: 6p21.3

HMGN4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HMGN4 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P026538:  view genomic region     (about GC identifiers)

Start:
26,538,572 bp from pter      End:
26,547,165 bp from pter
Size:
8,594 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: HMGN4_HUMAN, O00479 (See protein sequence)
Recommended Name: High mobility group nucleosome-binding domain-containing protein 4  
Size: 90 amino acids; 9539 Da
Subcellular location: Nucleus (By similarity)
Secondary accessions: B2R4I6 Q53XL9

Explore the universe of human proteins at neXtProt for HMGN4: NX_O00479

Explore proteomics data for HMGN4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O00479

  • HMGN4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    HMGN4 Protein Expression
    REFSEQ proteins: NP_006344.1  
    ENSEMBL proteins: 
     ENSP00000366798  

    Human Recombinant Protein Products for HMGN4: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for HMGN4
    OriGene Protein Over-expression Lysate for HMGN4
    OriGene MassSpec for HMGN4 
    OriGene Custom Protein Services for HMGN4
    GenScript Custom Purified and Recombinant Proteins Services for HMGN4
    Novus Biologicals HMGN4 Protein
    Novus Biologicals HMGN4 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for HMGN4 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000785chromatin IEA--
    GO:0005634nucleus IDA--

    HMGN4 for ontologies           About GeneDecksing



    HMGN4 Antibody Products: 
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    Abcam antibodies for HMGN4
    Cloud-Clone Corp. Antibodies for HMGN4 
    ThermoFisher Antibodies for HMGN4
    LSBio Antibodies in human, mouse, rat for HMGN4 

    Assay Products for HMGN4: 
    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for HMGN4
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for HMGN4 
    Cloud-Clone Corp. CLIAs for HMGN4


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    HMG: High-mobility group / Canonical

    1 InterPro protein domain:
     IPR000079 HMGN_fam

    Graphical View of Domain Structure for InterPro Entry O00479

    ProtoNet protein and cluster: O00479

    1 Blocks protein domain: IPB000079 High mobility group protein HMG14 and HMG17

    UniProtKB/Swiss-Prot: HMGN4_HUMAN, O00479
    Similarity: Belongs to the HMGN family


    HMGN4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0031492nucleosomal DNA binding IEA--
         
    HMGN4 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for HMGN4:
     Decreased viability of wild-ty 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for HMGN4 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for HMGN4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HMGN4 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HMGN4 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HMGN4
    8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate HMGN4 (see all 9):
    hsa-miR-3163 hsa-miR-548e hsa-miR-548o hsa-miR-340 hsa-miR-3692 hsa-miR-548a-3p hsa-miR-1323 hsa-miR-186
    SwitchGear 3'UTR luciferase reporter plasmidHMGN4 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for HMGN4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HMGN4

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for HMGN4
    Sirion Biotech Customized adenovirus for overexpression of HMGN4

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for HMGN4 (see all 7)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: HMGN4 (NM_006353)
    Sino Biological Human cDNA Clone for HMGN4
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HMGN4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HMGN4
    Sirion Biotech Customized lentivirus for stable overexpression of HMGN4 
                         Customized lentivirus expression plasmids for stable overexpression of HMGN4 

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for HMGN4
    Search LifeMap BioReagents cell lines for HMGN4
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HMGN4


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HMGN4

    1 Interacting protein for HMGN4 (O004793) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EWSR1Q018443I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HMGN4

    Search CenterWatch for drugs/clinical trials and news about HMGN4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for HMGN4 gene: 
    NM_006353.2  

    Unigene Cluster for HMGN4:

    High mobility group nucleosomal binding domain 4
    Hs.236774  [show with all ESTs]
    Unigene Representative Sequence: NM_006353
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000377575 ENST00000477243
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HMGN4
    8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate HMGN4 (see all 9):
    hsa-miR-3163 hsa-miR-548e hsa-miR-548o hsa-miR-340 hsa-miR-3692 hsa-miR-548a-3p hsa-miR-1323 hsa-miR-186
    SwitchGear 3'UTR luciferase reporter plasmidHMGN4 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for HMGN4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HMGN4
    Clone
    Products:
         
    OriGene clones in human, mouse for HMGN4 (see all 7)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: HMGN4 (NM_006353)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HMGN4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HMGN4
    Sirion Biotech Customized lentivirus for stable overexpression of HMGN4 
                         Customized lentivirus expression plasmids for stable overexpression of HMGN4 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for HMGN4
    OriGene qSTAR qPCR primer pairs in human, mouse for HMGN4
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat HMGN4
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HMGN4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HMGN4

    Additional mRNA sequence: 

    AK311841.1 BC001282.1 BC035998.1 BT009824.1 

    7 DOTS entries:

    DT.75139983  DT.100823375  DT.100823379  DT.92443710  DT.95136662  DT.100823378  DT.91945958 

    24/359 AceView cDNA sequences (see all 359):

    CR621282 BM782566 CA412884 AW239297 N53390 AA487257 BM971905 BM550944 
    CR613004 BM313743 AA865845 AA487374 BI520294 BM968231 AA707270 CR601032 
    AA828479 CR606138 AA487320 BM836380 CB121612 CA405940 BF058150 N53731 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for HMGN4    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c · 5d · 5e
    SP1:                          -           -                                       
    SP2:                          -     -                                             
    SP3:                          -     -     -                                       
    SP4:                                -                                             
    SP5:                          -     -     -     -                                 


    ECgene alternative splicing isoforms for HMGN4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HMGN4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATATGGTAC
    HMGN4 Expression
    About this image


    See HMGN4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HMGN4

    SOURCE GeneReport for Unigene cluster: Hs.236774
        SABiosciences Custom PCR Arrays for HMGN4
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for HMGN4
    OriGene qSTAR qPCR primer pairs in human, mouse for HMGN4
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat HMGN4
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HMGN4
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HMGN4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HMGN4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for HMGN4 gene from 3/7 species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hmgn2l65 high-mobility group nucleosomal binding domain 2-like more   --   X (62.61 cM) 141870135 
    chicken
    (Gallus gallus)
    Aves HMGN26
    Non-histone chromosomal protein HMG-17
    83(a)
    1 → many
    23(155931-159391)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    82(a)
    1 → many
    GL343480.1(638060-642947)


    ENSEMBL Gene Tree for HMGN4 (if available)
    TreeFam Gene Tree for HMGN4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HMGN4 gene
    HMGN22  
    1 SIMAP similar gene for HMGN4 using alignment to 1 protein entry:     HMGN4_HUMAN:
    HMGN2

    HMGN4 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for HMGN4
    PGOHUM00000258931 PGOHUM00000259817


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/215 SNPs in HMGN4 are shown (see all 215)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1429856371,2
    C--26536638(+) CGGCT-/GGG   
       GGGGG
    GTTGA
    1 -- us2k10--------
    rs94677791,2
    C,F,A,H--26536687(+) AGTGTT/ATATTC 1 -- us2k131Minor allele frequency- A:0.45NS EA NA WA CSA 2901
    rs737384811,2
    C,F--26536775(+) TTCTCC/AGAAAT 1 -- us2k11Minor allele frequency- A:0.50WA 2
    rs1929231951,2
    --26536782(+) AAATAC/TGGACA 1 -- us2k10--------
    rs799619701,2
    C,F--26536804(+) ACACAT/CATGAG 1 -- us2k11Minor allele frequency- C:0.03EA 120
    rs1841457151,2
    --26536807(+) CATATG/TAGACG 1 -- us2k10--------
    rs121114961,2
    C,F,H--26536886(+) AGCTGT/CCAAAT 1 -- us2k1 tfbs36Minor allele frequency- C:0.01NS EA NA 560
    rs114236661,2
    C--26536970(+) AAAAAA/-GACCC 1 -- us2k1 trp31Minor allele frequency- -:0.00CSA 2
    rs2016218681,2
    C--26536970(+) TTGAAA/GAAAAA 1 -- us2k10--------
    rs2012678221,2
    C--26536984(-) TGGGTC/TTTTTT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for HMGN4 (26538572 - 26547165 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for HMGN4: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing HMGN4
    DNA2.0 Custom Variant and Variant Library Synthesis for HMGN4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for HMGN4:    About MalaCards
    hypophosphatasia    hemochromatosis


    HMGN4 for disorders           About GeneDecksing

    Genetic Association Database (GAD): HMGN4

    Export disorders for HMGN4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HMGN4 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with HMGN4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A 1.1-Mb transcript map of the hereditary hemochromatosis locus. (PubMed id 9149941)1, 2, 3 Ruddy D.A.... Feder J.N. (1997)
    2. HMGN4, a newly discovered nucleosome-binding protein encoded by an intronless gene. (PubMed id 11410162)1, 3, 9 Birger Y....Bustin M. (2001)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    5. Genome-wide YFP fluorescence complementation screen id entifies new regulators for telomere signaling in human cells. (PubMed id 21044950)1 Lee O.H....Songyang Z. (2011)
    6. An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (2010)
    7. Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (2009)
    8. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
    9. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    10. Genome-wide association with bone mass and geometry in the Framingham Heart Study. (PubMed id 17903296)4 Kiel D.P....Karasik D. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10473 HGNC: 4989 AceView: HMGN4 Ensembl:ENSG00000182952 euGenes: HUgn10473
    ECgene: HMGN4 H-InvDB: HMGN4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HMGN4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for HMGN4 gene:
    Search GeneIP for patents involving HMGN4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
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     Regulatory tfbs in HMGN4 promoter
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     Proteins for HMGN4
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     ThermoFisher Antibodies for HMGN4
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HMGN4
     inGenious Targeting Laboratory - Custom generated mouse model solutions for HMGN4
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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