Aliases for HMGN2P46 Gene
Aliases for HMGN2P46 Gene
- High Mobility Group Nucleosomal Binding Domain 2 Pseudogene 46 2 3 5
- C15orf21 3 4
- D-PCa-2 3 4
- High Mobility Group Nucleosome-Binding Domain-Containing Protein 2 Pseudogene 46 4
- High-Mobility Group Nucleosomal Binding Domain 2 Pseudogene 46 2
- Chromosome 15 Open Reading Frame 21 2
- Dresden Prostate Carcinoma 2 3
- Dresden Prostate Cancer 2 3
External Ids for HMGN2P46 Gene
- HGNC: 26817
- Entrez Gene: 283651
- Ensembl: ENSG00000179362
- OMIM: 611314
- UniProtKB: Q86SG4
Previous HGNC Symbols for HMGN2P46 Gene
- C15orf21
Previous GeneCards Identifiers for HMGN2P46 Gene
- GC15P045804
Summaries for HMGN2P46 Gene
GeneCards Summary for HMGN2P46 Gene
HMGN2P46 (High Mobility Group Nucleosomal Binding Domain 2 Pseudogene 46) is a Pseudogene. Diseases associated with HMGN2P46 include Prostate Cancer.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HMGN2P46 Gene
Genomics for HMGN2P46 Gene
Regulatory Elements for HMGN2P46 Gene
Enhancers for HMGN2P46 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH15G045022 | 1 | ENCODE | 5.1 | -487.7 | -487677 | 2.0 | CREB3L1 AGO1 ARID4B SIN3A DMAP1 ZNF2 ZNF48 YY1 SP3 MXD4 | SORD HMGN2P46 GC15M045029 PIR54221 |
| GH15G045521 | 0.9 | ENCODE | 0.4 | +11.4 | 11352 | 2.4 | FOXA2 SIN3A ZNF48 YY1 ZNF143 REST HMBOX1 HNF4A CTCF SUZ12 | EIF3J-AS1 BLOC1S6 SLC30A4 HMGN2P46 |
| GH15G045514 | 0.3 | FANTOM5 | 0.7 | +3.3 | 3325 | 0.1 | HMGN2P46 SLC30A4 | |
| GH15G045492 | 0.3 | FANTOM5 | 0.4 | -18.8 | -18825 | 0.2 | C15orf48 SQOR BLOC1S6 PIR34649 HMGN2P46 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around HMGN2P46 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for HMGN2P46 Gene
- Chromosome:
- 15
- Start:
- 45,511,136 bp from pter
- End:
- 45,586,290 bp from pter
- Size:
- 75,155 bases
- Orientation:
- Plus strand
Genomic View for HMGN2P46 Gene
Genes around HMGN2P46 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 15q21.1 by Ensembl
- 15q21.1 by Entrez Gene
- 15q21.1 by HGNC
HMGN2P46 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HMGN2P46 Gene
Proteins for HMGN2P46 Gene
-
Protein details for HMGN2P46 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q86SG4-DPCA2_HUMAN
- Recommended name:
- Putative Dresden prostate carcinoma protein 2
- Protein Accession:
- Q86SG4
- Q495B5
- Q86SH8
- Q8N8I5
Protein attributes for HMGN2P46 Gene
- Size:
- 172 amino acids
- Molecular mass:
- 20403 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for HMGN2P46 Gene
No Post-translational modifications
Protein Products
-
OriGene Purified Proteins for HMGN2P46
- Search Origene for MassSpec and Protein Over-expression Lysates for HMGN2P46
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- Search GeneTex for Proteins for HMGN2P46
Assay Products
No data available for DME Specific Peptides for HMGN2P46 Gene
Domains & Families for HMGN2P46 Gene
Protein Domains for HMGN2P46 Gene
- ProtoNet:
Suggested Antigen Peptide Sequences for HMGN2P46 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families and UniProtKB/Swiss-Prot for HMGN2P46 Gene
Function for HMGN2P46 Gene
Phenotypes for HMGN2P46 Gene
- GenomeRNAi human phenotypes for HMGN2P46:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Search ViGene Biosciences for HMGN2P46
CRISPR Products
-
OriGene CRISPR knockouts for HMGN2P46
miRNA Products
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Inhibitory RNA Products
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Cell Line Products
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Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HMGN2P46 Gene
Localization for HMGN2P46 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for HMGN2P46 Gene
Transcripts for HMGN2P46 Gene
mRNA/cDNA for HMGN2P46 Gene
- (5) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (73) Selected AceView cDNA sequences:
- (8) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for HMGN2P46 Gene
CRISPR Products
-
OriGene CRISPR knockouts for HMGN2P46
miRNA Products
- Search ViGene Biosciences for HMGN2P46
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HMGN2P46
- Browse OriGene Inhibitory RNA Products For HMGN2P46
- Search ViGene Biosciences for HMGN2P46
Flow Cytometry Products
Expression for HMGN2P46 Gene
mRNA differential expression in normal tissues according to GTEx for HMGN2P46 Gene
This gene is overexpressed in Prostate (x20.0).
NURSA nuclear receptor signaling pathways regulating expression of HMGN2P46 Gene:
HMGN2P46SOURCE GeneReport for Unigene cluster for HMGN2P46 Gene:
Hs.574240mRNA Expression by UniProt/SwissProt for HMGN2P46 Gene:
Q86SG4-DPCA2_HUMAN
Tissue specificity:
Very high expression in prostate and prostate cancer. Faint expression in other tissues.
Primer Products
-
OriGene qPCR primer pairs for HMGN2P46
-
OriGene qPCR primer pairs and template standards for HMGN2P46
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HMGN2P46 Gene
Orthologs for HMGN2P46 Gene
No data available for Orthologs for HMGN2P46 Gene
Paralogs for HMGN2P46 Gene
No data available for Paralogs for HMGN2P46 Gene
Variants for HMGN2P46 Gene
| SNP ID | Clin | Chr 15 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000027595 | -- | 45,533,493(+) | AATCT(C/T)GGCTC | intron-variant | |
| rs1000055578 | -- | 45,509,698(+) | TACTT(A/G)GAATA | intron-variant, upstream-variant-2KB | |
| rs1000178384 | -- | 45,529,009(+) | TGCCT(C/T)AGATG | intron-variant | |
| rs1000232470 | -- | 45,529,289(+) | TCACT(G/T)TGTTA | intron-variant | |
| rs1000241373 | -- | 45,536,524(+) | CCTCC(C/G)GGGTT | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3569553 | CNV | gain | 25503493 |
| esv3892684 | CNV | gain | 25118596 |
| nsv1045556 | CNV | gain | 25217958 |
| nsv1160292 | CNV | duplication | 26073780 |
| nsv984066 | CNV | duplication | 23825009 |
Relevant External Links for HMGN2P46 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- HMGN2P46
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HMGN2P46 Gene
Disorders for HMGN2P46 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| prostate cancer |
|
|
Search HMGN2P46 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for HMGN2P46
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- HMGN2P46
No data available for UniProtKB/Swiss-Prot and Genatlas for HMGN2P46 Gene
Publications for HMGN2P46 Gene
- D-PCa-2: a novel transcript highly overexpressed in human prostate and prostate cancer. (PMID: 15027122) Weigle B. … Rieber E.P. (Int. J. Cancer 2004) 2 3 4 64
- A New RNA-Seq Method to Detect the Transcription and Non-coding RNA in Prostate Cancer. (PMID: 24043589) Zhang X.M. … Men T.Y. (Pathol. Oncol. Res. 2014) 2 3 64
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- Retroposed copies of the HMG genes: a window to genome dynamics. (PMID: 12727900) Strichman-Almashanu L.Z. … Landsman D. (Genome Res. 2003) 2 3 64
- Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3 64
Products for HMGN2P46 Gene
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- OriGene qPCR primer pairs for HMGN2P46
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- Novus Biologicals
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- VectorBuilder custom plasmid, inducible vectors for HMGN2P46
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- Mammalian expression: PiggyBac
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- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for HMGN2P46 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
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- (122) diseasecard
- (123) NIH Rare Diseases
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- (128) Genetics Home Reference
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- (130) MedlinePlus
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- (133) NCBI Bookshelf
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- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer