Aliases for HMGCLL1 Gene
Aliases for HMGCLL1 Gene
- 3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase Like 1 2 3 5
- Endoplasmic Reticulum 3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase 3 4
- 3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase-Like Protein 1 3 4
- 3-Hydroxymethyl-3-Methylglutaryl-Coenzyme A Lyase-Like 1 2 3
- EC 4.1.3.4 4 61
- Er-CHL 3 4
- 3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase, Cytoplasmic 3
- Probable 3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase 2 3
- BA418P12.1 3
External Ids for HMGCLL1 Gene
- HGNC: 21359
- Entrez Gene: 54511
- Ensembl: ENSG00000146151
- UniProtKB: Q8TB92
Previous GeneCards Identifiers for HMGCLL1 Gene
- GC06M055300
- GC06M055346
- GC06M055133
- GC06M055299
Summaries for HMGCLL1 Gene
GeneCards Summary for HMGCLL1 Gene
HMGCLL1 (3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase Like 1) is a Protein Coding gene. Among its related pathways are Peroxisome and Ketone body metabolism. GO annotations related to this gene include lyase activity and hydroxymethylglutaryl-CoA lyase activity. An important paralog of this gene is HMGCL.
UniProtKB/Swiss-Prot for HMGCLL1 Gene
-
Non-mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis, the products of which support energy production in nonhepatic animal tissues.
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HMGCLL1 Gene
Genomics for HMGCLL1 Gene
Regulatory Elements for HMGCLL1 Gene
Enhancers for HMGCLL1 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH06G055578 | 0.9 | ENCODE | 13.9 | +100.5 | 100518 | 0.7 | ZNF2 GLIS2 KLF7 ZNF263 ZNF202 SP3 ZNF610 KDM1A HNF4A SP7 | HMGCLL1 GC06P055585 GC06M055481 |
| GH06G055635 | 0.7 | ENCODE | 10.9 | +43.0 | 43021 | 3.2 | JUN CEBPG CTBP1 GATA3 FOSL2 FOS CEBPB CHD1 ZHX2 MNT | HMGCLL1 ENSG00000224984 GC06P055627 GC06P055628 GC06P055629 GC06P055630 GC06P055631 GC06P055635 GC06P055634 GC06P055633 |
| GH06G055704 | 0.6 | ENCODE | 10.9 | -25.0 | -24979 | 1.2 | JUND JUN FOS PRDM1 FOXA1 NR2F2 FOXP1 | HMGCLL1 PIR48007 GC06P055722 |
| GH06G055553 | 0.3 | FANTOM5 | 11.4 | +125.8 | 125806 | 0.1 | HMGCLL1 GC06P055585 GC06M055481 | |
| GH06G055705 | 0.2 | ENCODE | 10.9 | -25.9 | -25850 | 0.2 | HMGCLL1 PIR48007 GC06P055722 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around HMGCLL1 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the HMGCLL1 gene promoter:
Regulatory Element Products
Genomic Location for HMGCLL1 Gene
- Chromosome:
- 6
- Start:
- 55,434,369 bp from pter
- End:
- 55,679,668 bp from pter
- Size:
- 245,300 bases
- Orientation:
- Minus strand
Genomic View for HMGCLL1 Gene
Genes around HMGCLL1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p12.1 by Ensembl
- 6p12.1 by Entrez Gene
- 6p12.1 by HGNC
HMGCLL1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HMGCLL1 Gene
Proteins for HMGCLL1 Gene
-
Protein details for HMGCLL1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8TB92-HMGC2_HUMAN
- Recommended name:
- 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic
- Protein Accession:
- Q8TB92
- B1AQ42
- B3KNV0
- B7Z1S7
- F8W793
- Q6ZSA9
Protein attributes for HMGCLL1 Gene
- Size:
- 370 amino acids
- Molecular mass:
- 39514 Da
- Cofactor:
- Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAC87045.1; Type=Frameshift; Positions=253; Evidence={ECO:0000305}; Sequence=BAG51462.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305};
Protein Expression for HMGCLL1 Gene
Selected DME Specific Peptides for HMGCLL1 Gene
- Q8TB92:
-
- EVGPRDGLQNE
- NCSIEES
- ALAVHCHDTYGQAL
- GASGNVATEDL
- YPVLTPN
- MGCYEISLGDTIGVGTPG
Post-translational modifications for HMGCLL1 Gene
Other Protein References for HMGCLL1 Gene
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for HMGCLL1
- Novus Biologicals Antibodies for HMGCLL1
- antibodies-online Antibodies for HMGCLL1: See all 7
- GeneTex HMGCLL1 antibody for HMGCLL1
Protein Products
-
OriGene Purified Proteins for HMGCLL1
- Search Origene for MassSpec and Protein Over-expression Lysates for HMGCLL1
- Origene Custom Protein Services for HMGCLL1
- antibodies-online Proteins for HMGCLL1: See all 6
- Search antibodies-online for peptides
- Search GeneTex for Proteins for HMGCLL1
Assay Products
Domains & Families for HMGCLL1 Gene
Protein Domains for HMGCLL1 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for HMGCLL1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q8TB92- Family:
-
- Belongs to the HMG-CoA lyase family.
No data available for Gene Families for HMGCLL1 Gene
Function for HMGCLL1 Gene
Molecular function for HMGCLL1 Gene
- UniProtKB/Swiss-Prot BiophysicochemicalProperties:
- Kinetic parameters: KM=40 uM for (S)-3-hydroxy-3-methylglutaryl-CoA (at pH 9) {ECO:0000269 PubMed:22847177, ECO:0000269 PubMed:22865860}; KM=75 uM for (S)-3-hydroxy-3-methylglutaryl-CoA (at pH 8) {ECO:0000269 PubMed:22847177, ECO:0000269 PubMed:22865860}; KM=28 uM for (S)-3-hydroxy-3-methylglutaryl-CoA {ECO:0000269 PubMed:22847177, ECO:0000269 PubMed:22865860}; KM=49 uM for (S)-3-hydroxy-3-methylglutaryl-CoA (in presence of magnesium) {ECO:0000269 PubMed:22847177, ECO:0000269 PubMed:22865860}; KM=0.18 uM for (S)-3-hydroxy-3-methylglutaryl-CoA (in presence of manganese) {ECO:0000269 PubMed:22847177, ECO:0000269 PubMed:22865860}; Vmax=12 nmol/min/mg enzyme with (S)-3-hydroxy-3-methylglutaryl- CoA as substrate at pH 9 {ECO:0000269 PubMed:22847177, ECO:0000269 PubMed:22865860}; Vmax=25 nmol/min/mg enzyme with (S)-3-hydroxy-3-methylglutaryl- CoA as substrate at pH 8 {ECO:0000269 PubMed:22847177, ECO:0000269 PubMed:22865860};
- UniProtKB/Swiss-Prot CatalyticActivity:
- (S)-3-hydroxy-3-methylglutaryl-CoA = acetyl-CoA + acetoacetate.
- UniProtKB/Swiss-Prot Function:
- Non-mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis, the products of which support energy production in nonhepatic animal tissues.
Enzyme Numbers (IUBMB) for HMGCLL1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004419 | hydroxymethylglutaryl-CoA lyase activity | IEA,TAS | -- |
| GO:0016829 | lyase activity | IEA | -- |
| GO:0046872 | metal ion binding | TAS | 22865860 |
Phenotypes for HMGCLL1 Gene
- GenomeRNAi human phenotypes for HMGCLL1:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for HMGCLL1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HMGCLL1 gene
- Search ViGene Biosciences for HMGCLL1
CRISPR Products
-
OriGene CRISPR knockouts for HMGCLL1
-
Santa Cruz Biotechnology (SCBT) CRISPR for HMGCLL1
- GenScript: Design CRISPR guide RNA sequences for HMGCLL1
miRNA for HMGCLL1 Gene
- miRTarBase miRNAs that target HMGCLL1
-
- hsa-mir-335-5p (MIRT019060)
- hsa-mir-4635 (MIRT447458)
- hsa-mir-5585-3p (MIRT447459)
- hsa-mir-6772-3p (MIRT724264)
- hsa-mir-670-5p (MIRT724265)
- hsa-mir-4448 (MIRT724266)
- hsa-mir-4268 (MIRT724267)
- hsa-mir-1976 (MIRT724268)
- hsa-mir-6870-3p (MIRT724269)
- hsa-mir-6893-3p (MIRT724270)
- hsa-mir-370-3p (MIRT724271)
- hsa-mir-660-3p (MIRT724272)
- hsa-mir-5193 (MIRT724273)
- hsa-mir-6891-3p (MIRT724274)
- hsa-mir-6072 (MIRT724275)
- hsa-mir-4319 (MIRT724276)
- hsa-mir-125b-5p (MIRT724277)
- hsa-mir-125a-5p (MIRT724278)
- hsa-mir-4732-3p (MIRT724279)
- hsa-mir-345-3p (MIRT724280)
- hsa-mir-6729-3p (MIRT724281)
miRNA Products
- Search ViGene Biosciences for HMGCLL1
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for HMGCLL1
- Browse OriGene Inhibitory RNA Products For HMGCLL1
-
ViGene Biosciences ready-to-package AAV shRNAs for HMGCLL1 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for HMGCLL1
Cell Line Products
-
Horizon Cell Lines for HMGCLL1
-
ViGene Biosciences adenoviral particle packaged cDNA for HMGCLL1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for HMGCLL1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HMGCLL1 gene
Flow Cytometry Products
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for HMGCLL1 Gene
Localization for HMGCLL1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for HMGCLL1 Gene
- Cytoplasm, cytosol. Endoplasmic reticulum membrane; Peripheral membrane protein.
| Compartment | Confidence |
|---|---|
| endoplasmic reticulum | 5 |
| cytosol | 5 |
| mitochondrion | 3 |
| nucleus | 2 |
| extracellular | 1 |
| peroxisome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005783 | endoplasmic reticulum | IEA,IDA | 22847177 |
| GO:0005789 | endoplasmic reticulum membrane | IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
| GO:0016020 | membrane | IDA,IEA | 22865860 |
Pathways & Interactions for HMGCLL1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Metabolism |
.37
|
|
| 2 | Butanoate metabolism | ||
| 3 | Valine, leucine and isoleucine degradation | ||
| 4 | Ketone body metabolism | ||
| 5 | Peroxisome | ||
Pathways by source for HMGCLL1 Gene
1 BioSystems pathway for HMGCLL1 Gene
5 Reactome pathways for HMGCLL1 Gene
5 KEGG pathways for HMGCLL1 Gene
UniProtKB/Swiss-Prot Q8TB92-HMGC2_HUMAN
- Pathway: Metabolic intermediate metabolism; (S)-3-hydroxy-3-methylglutaryl-CoA degradation; acetoacetate from (S)-3-hydroxy-3-methylglutaryl-CoA: step 1/1.
Interacting Proteins for HMGCLL1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0046951 | ketone body biosynthetic process | TAS,IEA | -- |
No data available for SIGNOR curated interactions for HMGCLL1 Gene
Drugs & Compounds for HMGCLL1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Acetoacetic acid | Experimental | Pharma | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| 3-hydroxy-3-methylglutaryl-coa |
|
1553-55-5 |
|
|||
| acetyl-coa |
|
72-89-9 |
|
Transcripts for HMGCLL1 Gene
mRNA/cDNA for HMGCLL1 Gene
- (6) REFSEQ mRNAs :
- (6) Additional mRNA sequences :
- (28) Selected AceView cDNA sequences:
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for HMGCLL1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for HMGCLL1
-
Santa Cruz Biotechnology (SCBT) CRISPR for HMGCLL1
- GenScript: Design CRISPR guide RNA sequences for HMGCLL1
miRNA Products
- Search ViGene Biosciences for HMGCLL1
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for HMGCLL1
- Browse OriGene Inhibitory RNA Products For HMGCLL1
-
ViGene Biosciences ready-to-package AAV shRNAs for HMGCLL1 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for HMGCLL1
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||
| SP7: |
Expression for HMGCLL1 Gene
mRNA differential expression in normal tissues according to GTEx for HMGCLL1 Gene
This gene is overexpressed in Brain - Anterior cingulate cortex (BA24) (x4.7), Brain - Frontal Cortex (BA9) (x4.5), and Brain - Hypothalamus (x4.3).
This gene is overexpressed in Heart (36.6) and Liver (32.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for HMGCLL1 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of HMGCLL1 Gene:
HMGCLL1SOURCE GeneReport for Unigene cluster for HMGCLL1 Gene:
Hs.147054Evidence on tissue expression from TISSUES for HMGCLL1 Gene
- Nervous system(4.7)
Primer Products
-
OriGene qPCR primer pairs for HMGCLL1
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for HMGCLL1 Gene
Orthologs for HMGCLL1 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | HMGCLL1 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | HMGCLL1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | HMGCLL1 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Hmgcll1 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Hmgcll1 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | HMGCLL1 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | HMGCLL1 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | HMGCLL1 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | HMGCLL1 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | hmgcll1 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | hmgcll1 34 35 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG10399 35 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | Y71G12B.10 35 |
|
OneToMany | |
| rice (Oryza sativa) |
Liliopsida | Os12g0134000 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToMany |
- Species where no ortholog for HMGCLL1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for HMGCLL1 Gene
(2) SIMAP similar genes for HMGCLL1 Gene using alignment to 5 proteins:
Variants for HMGCLL1 Gene
| SNP ID | Clin | Chr 06 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000007559 | -- | 55,445,632(+) | ACTTT(C/G)AGACT | intron-variant | |
| rs1000012671 | -- | 55,455,132(+) | AAGTA(C/G/T)AGAAT | intron-variant | |
| rs1000047578 | -- | 55,481,982(+) | TTCCA(A/T)TTTTT | intron-variant | |
| rs1000060063 | -- | 55,561,907(+) | TACGA(G/T)AAACT | intron-variant | |
| rs1000102474 | -- | 55,532,327(+) | AAACA(A/G)TAAAA | intron-variant |
Residual Variation Intolerance Score:
44% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.35;
26.78% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for HMGCLL1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- HMGCLL1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HMGCLL1 Gene
Disorders for HMGCLL1 Gene
Relevant External Links for HMGCLL1
No disorders were found for HMGCLL1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HMGCLL1 Gene
Publications for HMGCLL1 Gene
- Characterization of a novel HMG-CoA Lyase enzyme with a dual location in endoplasmic reticulum and cytosol. (PMID: 22847177) Arnedo M. … Pie J. (J. Lipid Res. 2012) 3 4 64
- Identification and characterization of an extramitochondrial human 3- Hydroxy-3-methylglutaryl-CoA lyase. (PMID: 22865860) Montgomery C. … Miziorko H.M. (J. Biol. Chem. 2012) 3 4 64
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- Large-scale concatenation cDNA sequencing. (PMID: 9110174) Yu W. … Gibbs R.A. (Genome Res. 1997) 2 3 64
Products for HMGCLL1 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for HMGCLL1
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for HMGCLL1
- Search Origene for MassSpec and Protein Over-expression Lysates for HMGCLL1
- Origene Custom Protein Services for HMGCLL1
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for HMGCLL1
- Browse OriGene Inhibitory RNA Products For HMGCLL1
- OriGene qPCR primer pairs for HMGCLL1
- OriGene CRISPR knockouts for HMGCLL1
- OriGene ORF clones in human for HMGCLL1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For HMGCLL1
- GenScript: Next-day shipping cDNA ORF clone for HMGCLL1 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for HMGCLL1
- GenScript Custom Assay Services for HMGCLL1
- GenScript Custom overexpressing Cell Line Services for HMGCLL1
- GenScript: Design CRISPR guide RNA sequences for HMGCLL1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for HMGCLL1
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for HMGCLL1
- Novus Biologicals proteins and lysates for HMGCLL1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for HMGCLL1
- antibodies-online Antibodies for HMGCLL1: See all 7
- Search antibodies-online for kits
- antibodies-online Proteins for HMGCLL1: See all 6
- Search antibodies-online for peptides
- GeneTex HMGCLL1 antibody for HMGCLL1
- Search GeneTex for Proteins for HMGCLL1
- ViGene Biosciences adenoviral particle packaged cDNA for HMGCLL1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for HMGCLL1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for HMGCLL1 gene
- Search ViGene Biosciences for HMGCLL1
- Horizon Cell Lines for HMGCLL1
- Cyagen custom Knockout/knockin (KOKI) mouse models for HMGCLL1
- VectorBuilder custom plasmid, inducible vectors for HMGCLL1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HMGCLL1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for HMGCLL1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer