Aliases for HMGB3 Gene
Aliases for HMGB3 Gene
External Ids for HMGB3 Gene
- HGNC: 5004
- Entrez Gene: 3149
- Ensembl: ENSG00000029993
- OMIM: 300193
- UniProtKB: O15347
Previous HGNC Symbols for HMGB3 Gene
- HMG4
Previous GeneCards Identifiers for HMGB3 Gene
- GC0XP144450
- GC0XP146834
- GC0XP147919
- GC0XP148792
- GC0XP149822
- GC0XP150148
- GC0XP139013
Summaries for HMGB3 Gene
-
This gene encodes a member of a family of proteins containing one or more high mobility group DNA-binding motifs. The encoded protein plays an important role in maintaining stem cell populations, and may be aberrantly expressed in tumor cells. A mutation in this gene was associated with microphthalmia, syndromic 13. There are numerous pseudogenes of this gene on multiple chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
GeneCards Summary for HMGB3 Gene
HMGB3 (High Mobility Group Box 3) is a Protein Coding gene. Diseases associated with HMGB3 include Microphthalmia, Syndromic 13 and Terminal Osseous Dysplasia. GO annotations related to this gene include poly(A) RNA binding and double-stranded DNA binding. An important paralog of this gene is HMGB1.
UniProtKB/Swiss-Prot for HMGB3 Gene
-
Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters (By similarity). Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor (By similarity). Negatively regulates B-cell and myeloid cell differentiation. In hematopoietic stem cells may regulate the balance between self-renewal and differentiation. Involved in negative regulation of canonical Wnt signaling (By similarity).
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HMGB3 Gene
Genomics for HMGB3 Gene
Regulatory Elements for HMGB3 Gene
Enhancers for HMGB3 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH0XG150846 | 1.5 | FANTOM5 Ensembl ENCODE | 11.7 | -130.7 | -130679 | 5.9 | FOXA2 ARID4B SIN3A YY1 TCF12 FOS ZNF592 SREBF1 MBD2 MIER3 | CD99L2 MTMR1 HMGB3 ENSG00000228728 |
| GH0XG150766 | 1 | Ensembl ENCODE | 12.4 | -213.1 | -213148 | 2.1 | CTCF MAX RAD21 FOSL1 NFYB FOS NFE2 MAFK NFE2L2 BHLHE40 | MTMR1 HMGB3 CD99L2 PIR43679 ENSG00000228728 |
| GH0XG151082 | 0.8 | Ensembl | 12 | +102.0 | 101993 | 0.6 | ATF1 RB1 SIN3A RAD21 ZNF143 PCBP1 FOS EGR2 ZNF654 CBFB | HMGB3 GC0XP151077 MIR4330 |
| GH0XG150871 | 0.6 | ENCODE | 12.1 | -107.4 | -107393 | 2.4 | GATA3 CTBP1 NFIB FOS DPF2 EMSY ZKSCAN1 FOXA1 | CD99L2 HMGB3 ENSG00000228728 |
| GH0XG150870 | 0.4 | FANTOM5 | 12.1 | -110.2 | -110168 | 0.4 | FOS | CD99L2 HMGB3 ENSG00000228728 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around HMGB3 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for HMGB3 Gene
- Chromosome:
- X
- Start:
- 150,980,508 bp from pter
- End:
- 150,990,775 bp from pter
- Size:
- 10,268 bases
- Orientation:
- Plus strand
Genomic View for HMGB3 Gene
Genes around HMGB3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- Xq28 by Ensembl
- Xq28 by Entrez Gene
- Xq28 by HGNC
HMGB3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HMGB3 Gene
Proteins for HMGB3 Gene
-
Protein details for HMGB3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O15347-HMGB3_HUMAN
- Recommended name:
- High mobility group protein B3
- Protein Accession:
- O15347
- O95556
- Q6NS40
Protein attributes for HMGB3 Gene
- Size:
- 200 amino acids
- Molecular mass:
- 22980 Da
- Quaternary structure:
- No Data Available
Protein Expression for HMGB3 Gene
Post-translational modifications for HMGB3 Gene
- Reduction/oxidation of cysteine residues Cys-23, Cys-45 and Cys-104 and a possible intramolecular disulfide bond involving Cys-23 and Cys-45 give rise to different redox forms with specific functional activities in various cellular compartments: 1- fully reduced HMGB3 (HMGB3C23hC45hC104h), 2- disulfide HMGB3 (HMGB3C23-C45C104h) and 3- sulfonyl HMGB3 (HMGB3C23soC45soC104so).
- Ubiquitination at posLast=112112
- Modification sites at PhosphoSitePlus
Other Protein References for HMGB3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for HMGB3 (HMGB3)
- Novus Biologicals Antibodies for HMGB3
-
Cloud-Clone Corp. Antibodies for HMGB3
- Invitrogen Antibodies for HMGB3
- antibodies-online Antibodies for HMGB3: See all 68
- GeneTex HMGB3 antibody for HMGB3
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for HMGB3
- Origene Custom Protein Services for HMGB3
- ProSpec Recombinant Proteins for HMGB3
-
Cloud-Clone Corp. Proteins for HMGB3
- antibodies-online Proteins for HMGB3: See all 8
- Search antibodies-online for peptides
- Search GeneTex for Proteins for HMGB3
-
ProSci Proteins for HMGB3
Assay Products
- antibodies-online Kits for HMGB3: See all 2
No data available for DME Specific Peptides for HMGB3 Gene
Domains & Families for HMGB3 Gene
Gene Families for HMGB3 Gene
Protein Domains for HMGB3 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for HMGB3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O15347- Family:
-
- Belongs to the HMGB family.
Function for HMGB3 Gene
Molecular function for HMGB3 Gene
- UniProtKB/Swiss-Prot Function:
- Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters (By similarity). Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor (By similarity). Negatively regulates B-cell and myeloid cell differentiation. In hematopoietic stem cells may regulate the balance between self-renewal and differentiation. Involved in negative regulation of canonical Wnt signaling (By similarity).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000400 | four-way junction DNA binding | ISS | -- |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003690 | double-stranded DNA binding | ISS | -- |
| GO:0003723 | RNA binding | IDA | 22681889 |
| GO:0005515 | protein binding | IPI | 21044950 |
Phenotypes for HMGB3 Gene
- GenomeRNAi human phenotypes for HMGB3:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for HMGB3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HMGB3 gene
- Search ViGene Biosciences for HMGB3
CRISPR Products
-
OriGene CRISPR knockouts for HMGB3
-
Santa Cruz Biotechnology (SCBT) CRISPR for HMGB3
- GenScript: Design CRISPR guide RNA sequences for HMGB3
miRNA for HMGB3 Gene
- miRTarBase miRNAs that target HMGB3
-
- bta-mir-17-5p (MIRT007159)
- bta-mir-20b (MIRT007160)
- bta-mir-93 (MIRT007161)
- hsa-mir-335-5p (MIRT018990)
- hsa-mir-148b-3p (MIRT019470)
- hsa-mir-106b-5p (MIRT020449)
- hsa-mir-21-5p (MIRT031042)
- hsa-mir-877-5p (MIRT037218)
- hsa-mir-124-3p (MIRT046106)
- hsa-mir-513b-5p (MIRT054134)
- hsa-mir-205-5p (MIRT437429)
- hsa-mir-6858-5p (MIRT493600)
- hsa-mir-4689 (MIRT493601)
- hsa-mir-4784 (MIRT493602)
- hsa-mir-3150b-3p (MIRT493603)
- hsa-mir-545-3p (MIRT493604)
- hsa-mir-759 (MIRT493605)
- hsa-mir-520h (MIRT493606)
- hsa-mir-520g-3p (MIRT493607)
- hsa-mir-5586-3p (MIRT493608)
- hsa-mir-4797-5p (MIRT493609)
- hsa-mir-3120-3p (MIRT493610)
- hsa-mir-519c-3p (MIRT493611)
- hsa-mir-519b-3p (MIRT493612)
- hsa-mir-519a-3p (MIRT493613)
- hsa-mir-93-5p (MIRT493614)
- hsa-mir-106a-5p (MIRT493615)
- hsa-mir-20b-5p (MIRT493616)
- hsa-mir-17-5p (MIRT493617)
- hsa-mir-519d-3p (MIRT493618)
- hsa-mir-20a-5p (MIRT493619)
- hsa-mir-526b-3p (MIRT493620)
miRNA Products
- Search ViGene Biosciences for HMGB3
Inhibitory RNA Products
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-
ViGene Biosciences ready-to-package AAV shRNAs for HMGB3 gene
Clone Products
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Cell Line Products
-
Horizon Cell Lines for HMGB3
-
ViGene Biosciences adenoviral particle packaged cDNA for HMGB3 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for HMGB3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HMGB3 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for HMGB3 Gene
Localization for HMGB3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for HMGB3 Gene
- Nucleus. Chromosome. Cytoplasm.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytoskeleton | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005694 | chromosome | IEA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
Pathways & Interactions for HMGB3 Gene
No Data Available
Interacting Proteins for HMGB3 Gene
Selected Interacting proteins:
ENSP00000359393
O15347-HMGB3_HUMAN
for HMGB3 Gene via
STRING
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002376 | immune system process | IEA | -- |
| GO:0006310 | DNA recombination | ISS | -- |
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0007275 | multicellular organism development | TAS | 9598312 |
No data available for Pathways by source and SIGNOR curated interactions for HMGB3 Gene
Transcripts for HMGB3 Gene
mRNA/cDNA for HMGB3 Gene
- (4) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (227) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for HMGB3 Gene
CRISPR Products
-
OriGene CRISPR knockouts for HMGB3
-
Santa Cruz Biotechnology (SCBT) CRISPR for HMGB3
- GenScript: Design CRISPR guide RNA sequences for HMGB3
miRNA Products
- Search ViGene Biosciences for HMGB3
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for HMGB3
- Browse OriGene Inhibitory RNA Products For HMGB3
-
ViGene Biosciences ready-to-package AAV shRNAs for HMGB3 gene
Clone Products
- Sino Biological Human cDNA Clone for HMGB3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||
| SP2: |
Expression for HMGB3 Gene
mRNA differential expression in normal tissues according to GTEx for HMGB3 Gene
This gene is overexpressed in Liver (x6.7).
This gene is overexpressed in Lung (14.0), Placenta (9.6), and Lavage (8.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for HMGB3 Gene
NURSA nuclear receptor signaling pathways regulating expression of HMGB3 Gene:
HMGB3SOURCE GeneReport for Unigene cluster for HMGB3 Gene:
Hs.19114mRNA Expression by UniProt/SwissProt for HMGB3 Gene:
O15347-HMGB3_HUMAN
Tissue specificity:
Expressed predominantly in placenta.
Evidence on tissue expression from TISSUES for HMGB3 Gene
- Eye(4.2)
- Liver(2.1)
Phenotype-based relationships between genes and organs from Gene ORGANizer for HMGB3 Gene
Germ Layers:
- ectoderm
- mesoderm
Systems:
- integumentary
- nervous
- skeletal muscle
- skeleton
Organs:
Head and neck:
- brain
- cerebellum
- cranial nerve
- ear
- eye
- eyelid
- face
- head
- outer ear
- skull
General:
- peripheral nervous system
- skin
Primer Products
-
OriGene qPCR primer pairs for HMGB3
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for HMGB3 Gene
Orthologs for HMGB3 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | HMGB3 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Hmgb3 35 |
|
OneToMany | |
| Gm6104 35 |
|
OneToMany | |||
| platypus (Ornithorhynchus anatinus) |
Mammalia | HMGB3 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | HMGB3 35 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | HMGB3 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | HMGB3 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | LOC688583 34 |
|
||
| chicken (Gallus gallus) |
Aves | HMGB3 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | HMGB3 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | hmgb3 34 |
|
||
| Str.2163 34 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | hmgb3-prov 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | hmgb3a 35 |
|
OneToMany | |
| hmgb3b 35 |
|
OneToMany | |||
| fruit fly (Drosophila melanogaster) |
Insecta | Dsp1 35 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | hmg-1.1 35 |
|
OneToMany | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | NHP6A 35 |
|
ManyToMany | |
| NHP6B 35 |
|
ManyToMany | |||
| IXR1 37 |
|
|
|||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.3845 35 |
|
OneToMany | |
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.2712 34 |
|
- Species where no ortholog for HMGB3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for HMGB3 Gene
(14) SIMAP similar genes for HMGB3 Gene using alignment to 4 proteins:
Pseudogenes.org Pseudogenes for HMGB3 Gene
- PGOHUM00000290625
- PGOHUM00000292235
- PGOHUM00000292452
- PGOHUM00000293879
- PGOHUM00000294442
- PGOHUM00000294732
- PGOHUM00000294905
- PGOHUM00000295748
- PGOHUM00000296418
- PGOHUM00000296983
- PGOHUM00000296987
- PGOHUM00000298600
- PGOHUM00000299375
- PGOHUM00000299601
- PGOHUM00000299602
- PGOHUM00000299925
- PGOHUM00000300717
- PGOHUM00000300737
- PGOHUM00000300864
- PGOHUM00000301212
- PGOHUM00000301528
- PGOHUM00000301601
- PGOHUM00000302078
- PGOHUM00000303767
- PGOHUM00000303791
- PGOHUM00000304859
- PGOHUM00000305256
- PGOHUM00000289998
Variants for HMGB3 Gene
| SNP ID | Clin | Chr 0X pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs431825172 | Pathogenic | 150,987,788(+) | CTGAC(-/TA)TATAA | reference, frameshift-variant | |
| rs587777541 | Pathogenic | 150,987,792(+) | CTATA(-/TA)AGTCG | reference, frameshift-variant | |
| rs1000038319 | -- | 150,989,146(+) | TGTCA(A/G)AAATT | utr-variant-3-prime | |
| rs1001262740 | -- | 150,989,703(+) | TATTG(C/G)CCAGC | utr-variant-3-prime | |
| rs1003740428 | -- | 150,981,385(+) | GGCCT(A/T)AAGAT | intron-variant, upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv4318n106 | CNV | deletion | 24896259 |
| nsv1077247 | CNV | deletion | 25765185 |
Residual Variation Intolerance Score:
29.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.10;
2.32% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for HMGB3 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HMGB3 Gene
Disorders for HMGB3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| microphthalmia, syndromic 13 |
|
|
| terminal osseous dysplasia |
|
|
| colobomatous microphthalmia |
|
|
| microphthalmia |
|
|
Search HMGB3 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
HMGB3_HUMAN- Microphthalmia, syndromic, 13 (MCOPS13) [MIM:300915]: A form of microphthalmia, a disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases, microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities. MCOPS13 patients exhibit colobomatous microphthalmia with microcephaly, short stature, and psychomotor retardation. {ECO:0000269 PubMed:24993872}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Relevant External Links for HMGB3
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- HMGB3
No data available for Genatlas for HMGB3 Gene
Publications for HMGB3 Gene
- Identification of an HMGB3 Frameshift Mutation in a Family With an X-linked Colobomatous Microphthalmia Syndrome Using Whole-Genome and X-Exome Sequencing. (PMID: 24993872) Scott A.F. … Jabs E.W. (JAMA Ophthalmol 2014) 3 4 64
- The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- Hmg4, a new member of the Hmg1/2 gene family. (PMID: 9598312) Vaccari T. … Bianchi M.E. (Genomics 1998) 2 3 64
- Isolation of human and mouse HMG2a cDNAs: evidence for an HMG2a- specific 3' untranslated region. (PMID: 9370291) Wilke K. … Poustka A. (Gene 1997) 3 4 64
Products for HMGB3 Gene
- R&D Systems Antibodies for HMGB3 (HMGB3)
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- antibodies-online Antibodies for HMGB3: See all 68
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- antibodies-online Proteins for HMGB3: See all 8
- Search antibodies-online for peptides
- GeneTex HMGB3 antibody for HMGB3
- Search GeneTex for Proteins for HMGB3
- ViGene Biosciences adenoviral particle packaged cDNA for HMGB3 gene
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- Custom Antibody Services
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- VectorBuilder custom plasmid, inducible vectors for HMGB3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HMGB3
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for HMGB3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
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- (27) AceView
- (28) RNAdb
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- (33) SOURCE
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- (40) Pseudogene
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- (43) GenAtlas
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- (50) eBioscience
- (51) Atlas
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- (62) NCBI
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- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
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- (90) Invitrogen
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- (92) Vector BioLabs
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- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
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- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
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- (141) ENCODE
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- (143) Horizon
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- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer