HMGB1P1 Gene
pseudogene GIFtS: 20
GCID: GC20M056062
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high mobility group box 1 pseudogene 1(Previous names: high-mobility group (nonhistone chromosomal) protein 1-like...)
(Previous symbols: HMG1L1, HMGB1L1)
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Aliases
for HMGB1P1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
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| Aliases |
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| High Mobility Group Box 1 Pseudogene 11 2 | | High-Mobility Group Box 1-Like 11 | | HMG1L11 2 3 | | DJ579F20.11 | | HMGB1L11 2 3 | | HMG-1L13 | | HMG1L71 2 | | High Mobility Group Protein B1 Pseudogene 13 | | High-Mobility Group (Nonhistone Chromosomal) Protein 1-Like 11 | | Putative High Mobility Group Protein 1-Like 13 | | High-Mobility Group Box 1 Pseudogene 11 | | |
Export aliases for HMGB1P1 gene to outside databases |
Summaries
for HMGB1P1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
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Entrez Gene summary for HMGB1P1:
This gene may represent an evolving retropseudogene of the high-mobility group box 1 gene, which has multiplepseudogenes. This gene has an intact open reading frame, where the length of encoded protein is conserved, compared tothe high-mobility group box 1 protein. However, due to the lack of conclusive evidence for specific transcription atthis location, this locus is currently represented as a pseudogene. (provided by RefSeq, Jan 2010)
UniProtKB/Swiss-Prot: HGB1A_HUMAN, B2RPK0Function: Binds preferentially single-stranded DNA and unwinds double stranded DNA (By similarity)
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Genomic Views
for HMGB1P1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for HMGB1P1
Other transcription factors
Search SABiosciences Chromatin IP Primers for HMGB1P1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HMGB1P1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20q13.32 Ensembl cytogenetic band: 20q13.31 HGNC cytogenetic band: 20q13HMGB1P1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20M056062: view genomic region
(about GC identifiers)
Start:
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56,062,997 bp from pter |
End:
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56,064,186 bp from pter |
Size:
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1,190 bases |
Orientation:
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minus strand |
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Proteins
for HMGB1P1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
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UniProtKB/Swiss-Prot: HGB1A_HUMAN, B2RPK0 (See
protein sequence)Recommended Name: Putative high mobility group protein B1-like 1 Size: 211 amino acids; 24238 Da
Subcellular location: Nucleus (By similarity). Chromosome (By similarity)
Caution: Could be the product of a pseudogeneExplore the universe of human proteins at neXtProt for HMGB1P1: NX_B2RPK0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_B2RPK0
HMGB1P1 Protein expression data from MOPED and PaxDb: About this image 
Human Recombinant Protein Products:
HMGB1P1 Antibody Products:
Assay Products for HMGB1P1: |
Protein
Domains /
Families
for HMGB1P1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
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HMGB1P1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry B2RPK0ProtoNet protein and cluster: B2RPK0 UniProtKB/Swiss-Prot: HGB1A_HUMAN, B2RPK0Similarity: Belongs to the HMGB familySimilarity: Contains 2 HMG box DNA-binding domains |
Function
for HMGB1P1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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Function Summary:
UniProtKB/Swiss-Prot: HGB1A_HUMAN, B2RPK0Function: Binds preferentially single-stranded DNA and unwinds double stranded DNA (By similarity)
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Pathways & Interactions
for HMGB1P1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HMGB1P1
|
Drugs & Compounds
for HMGB1P1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for HMGB1P1
Search CenterWatch for drugs/clinical trials and news about HMGB1P1 
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Transcripts
for HMGB1P1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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REFSEQ mRNAs for HMGB1P1 gene: NM_001008735.1 1 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000522557
GeneLoc Exon Structure
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Expression
for HMGB1P1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| HMGB1P1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See HMGB1P1 Protein Expression from SPIRE MOPED and PaxDB SABiosciences Custom PCR Arrays for HMGB1P1
Primer
Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HMGB1P1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat HMGB1P1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HMGB1P1 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HMGB1P1 |
Orthologs
for HMGB1P1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for HMGB1P1 (if available)
TreeFam Gene Tree for HMGB1P1 (if available) |
Paralogs
for HMGB1P1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
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Genomic Variants
for HMGB1P1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for HMGB1P1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
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Publications
for HMGB1P1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed articles for HMGB1P1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with HMGB1P1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Mapping and molecular characterization of five HMG1-related DNA sequences. (PubMed id 9925949)1, 3 Rogalla P....Bullerdiek J. (1998)
- Genome-wide association of lipid-lowering response to statins in combined study populations. (PubMed id 20339536)1 Barber M.J....Krauss R.M. (2010)
- Replication of previous genome-wide association studi es of bone mineral density in premenopausal American women. (PubMed id 20200978)1 Ichikawa S....Econs M.J. (2010)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)2 Deloukas P....Rogers J. (2001)
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External Searches for HMGB1P1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing HMGB1P1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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Other Databases showing HMGB1P1 gene
(According to HUGE)
About This Section
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Specialized Databases showing HMGB1P1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for HMGB1P1 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for HMGB1P1 gene:
Search GeneIP for patents involving HMGB1P1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for HMGB1P1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for HMGB1P1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HMGB1P1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HMGB1P1 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for HMGB1P1 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HMGB1P1 | | Browse OriGene Myc/DDK tagged cDNA clones in CMV expression vector | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for HMGB1P1 | | OriGene Custom Protein Services for HMGB1P1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HMGB1P1 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HMGB1P1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HMGB1P1 | | | Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HMGB1P1 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HMGB1P1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HMGB1P1 |
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| | | | Search Tocris compounds for HMGB1P1 |
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 | | | | |  |  |  | | | | Search ThermoFisher Antibodies for HMGB1P1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HMGB1P1 |
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