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HMG20B Gene

protein-coding   GIFtS: 58
GCID: GC19P003572

High Mobility Group 20B

(Previous name: high-mobility group 20B)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
High Mobility Group 20B1 2     SMARCE1-Related Protein2 3
BRAF352 3 5     Sox-Like Transcriptional Factor2 3
High-Mobility Group 20B1 2     BRAF252
HMG Box Domain Containing 21 2     PP77062
Structural DNA-Binding Protein BRAF352 3     SMARCE1r2
HMGX22 3     SOXL2
HMGXB22 3     pp88572
BRCA2-Associated Factor 352 3     SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin
Subfamily E Member 1-Related2
HMG Box-Containing Protein 20B2 3     SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin
Subfamily E, Member 1-Related2
HMG Domain-Containing Protein 22 3     SMARCE1R3
HMG Domain-Containing Protein HMGX22 3     

External Ids:    HGNC: 50021   Entrez Gene: 103622   Ensembl: ENSG000000649617   OMIM: 6055355   UniProtKB: Q9P0W23   

Export aliases for HMG20B gene to outside databases

Previous GC identifers: GC19P003665 GC19P003642 GC19P003512 GC19P003523 GC19P003338


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for HMG20B Gene:
HMG20B (high mobility group 20B) is a protein-coding gene. GO annotations related to this gene include protein heterodimerization activity and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is HMG20A.

UniProtKB/Swiss-Prot: HM20B_HUMAN, Q9P0W2
Function: Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for
RCOR1/CoREST mediated repression of neuronal specific gene promoters

Gene Wiki entry for HMG20B Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NC_018930.2  NT_011295.12  
Regulatory elements:
   Regulatory transcription factor binding sites in the HMG20B gene promoter:
         Max1   AP-4   LUN-1   STAT5A   HEN1   SRY   NRF-2   NF-Y   CBF(2)   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHMG20B promoter sequence
   Search Chromatin IP Primers for HMG20B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HMG20B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.3   Ensembl cytogenetic band:  19p13.3   HGNC cytogenetic band: 19p13.3

HMG20B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HMG20B gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P003572:  view genomic region     (about GC identifiers)

Start:
3,572,775 bp from pter      End:
3,579,086 bp from pter
Size:
6,312 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: HM20B_HUMAN, Q9P0W2 (See protein sequence)
Recommended Name: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member
1-related  
Size: 317 amino acids; 35813 Da
Subunit: Component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, KDM1A,
RCOR1/CoREST and PHF21A/BHC80. The BHC complex may also contain ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I. Interacts
with the BRCA2 tumor suppressor protein
Sequence caution: Sequence=AAC26860.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAC26860.1; Type=Frameshift; Positions=223; Sequence=AAH21585.1; Type=Erroneous initiation;
Secondary accessions: A6NMS5 D6W616 Q6IBP8 Q8NBD5 Q9HD21 Q9Y491 Q9Y4A2
Alternative splicing: 3 isoforms:  Q9P0W2-1   Q9P0W2-2   Q9P0W2-3   

Explore the universe of human proteins at neXtProt for HMG20B: NX_Q9P0W2

Explore proteomics data for HMG20B at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys208
  • Modification sites at PhosphoSitePlus

  • See HMG20B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_006330.2  
    ENSEMBL proteins: 
     ENSP00000410924   ENSP00000328269   ENSP00000393904   ENSP00000402877   ENSP00000393481  
     ENSP00000262949   ENSP00000465293  
    Reactome Protein details: Q9P0W2

    HMG20B Human Recombinant Protein Products:

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    antibodies-online peptides for HMG20B

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    HMGX: High mobility group / Non-canonical

    1 InterPro protein domain:
     IPR009071 HMG_box_dom

    Graphical View of Domain Structure for InterPro Entry Q9P0W2

    ProtoNet protein and cluster: Q9P0W2

    UniProtKB/Swiss-Prot: HM20B_HUMAN, Q9P0W2
    Similarity: Contains 1 HMG box DNA-binding domain


    Find genes that share domains with HMG20B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HM20B_HUMAN, Q9P0W2
    Function: Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for
    RCOR1/CoREST mediated repression of neuronal specific gene promoters

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity ----
    GO:0005515protein binding IPI--
    GO:0046982protein heterodimerization activity IEA--
         
    Find genes that share ontologies with HMG20B           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for HMG20B

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    SwitchGear 3'UTR luciferase reporter plasmidHMG20B 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    HM20B_HUMAN, Q9P0W2: Nucleus. Chromosome. Note=Localized to condensed chromosomes in mitosis in conjunction with
    BRCA2
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005654nucleoplasm TAS--
    GO:0005694chromosome IEA--
    GO:0005730NOT nucleolus IDA--

    Find genes that share ontologies with HMG20B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for HMG20B About    
    See pathways by source

    SuperPathContained pathways About
    1Hemostasis
    Hemostasis0.43
    2Packaging Of Telomere Ends
    Histone modification0.31
    3Factors involved in megakaryocyte development and platelet production
    Factors involved in megakaryocyte development and platelet production


    Find genes that share SuperPaths with HMG20B           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Reactome Pathway for HMG20B
        Factors involved in megakaryocyte development and platelet production


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HMG20B
    Interactions:

        GeneGlobe Interaction Network for HMG20B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for HMG20B (Q9P0W21, 2, 3 ENSP000003282694) via UniProtKB, MINT, STRING, and/or I2D (see all 40)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCDC85BQ158342, 3, ENSP000003116954MINT-67604 I2D: score=5 STRING: ENSP00000311695
    HNRNPLP148662, 3, ENSP000002214194MINT-65669 I2D: score=5 STRING: ENSP00000221419
    TACC2O953592, 3, ENSP000003342804MINT-65670 I2D: score=5 STRING: ENSP00000334280
    BRCA2P515871, 3, ENSP000003694974EBI-713401,EBI-79792 I2D: score=3 STRING: ENSP00000369497
    VIMP086702, 3MINT-65671 I2D: score=5 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006325chromatin organization ----
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--
    GO:0007049cell cycle IEA--
    GO:0007596blood coagulation TAS--

    Find genes that share ontologies with HMG20B           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HMG20B (HM20B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for HMG20B gene: 
    NM_006339.2  

    Unigene Cluster for HMG20B:

    High mobility group 20B
    Hs.406534  [show with all ESTs]
    Unigene Representative Sequence: AF318366
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000416526 ENST00000470356 ENST00000333651(uc002lya.3) ENST00000417382
    ENST00000453933 ENST00000435022 ENST00000488973(uc010dtm.1 uc002lyb.3)
    ENST00000262949(uc010xhn.1) ENST00000585741 ENST00000486028 ENST00000483417
    ENST00000487894 ENST00000464304 ENST00000493191 ENST00000585900 ENST00000461099

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    SwitchGear 3'UTR luciferase reporter plasmidHMG20B 3' UTR sequence
    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat HMG20B
      QuantiFast Probe-based Assays in human, mouse, rat HMG20B

    Additional mRNA sequence: 

    AF072165.1 AF072836.1 AF146223.1 AF288679.1 AF318366.1 AF331191.1 AK090733.1 AK129638.1 
    AK289500.1 AK310601.1 AK314201.1 AL355691.1 AL355698.1 AL355702.1 AL355703.1 AL355709.1 
    BC002552.2 BC003505.1 BC004408.1 BC021585.1 BC134413.1 CR456754.1 

    23 DOTS entries:

    DT.100796800  DT.121490066  DT.216918  DT.95075154  DT.95214581  DT.121490015  DT.92446847  DT.100796802 
    DT.121490095  DT.40132447  DT.92446838  DT.92446835  DT.95261735  DT.102833743  DT.121489999  DT.121490037 
    DT.452780  DT.92410224  DT.95075135  DT.95075156  DT.95075157  DT.101958792  DT.92446848 

    Selected AceView cDNA sequences (see all 490):

    BM717120 BP871466 BM727101 CA454413 BU931760 BM723116 BF125939 BE501849 
    BM665928 BG029223 BE280819 BU738582 BQ674843 BE501829 AI744318 BM823805 
    BM423856 BM793608 BE268187 BQ669075 BQ688018 AF331191 BG760860 BG760719 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for HMG20B (see all 14)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b · 6c ^ 7a · 7b · 7c ^ 8a · 8b ^ 9a · 9b · 9c ^ 10a · 10b · 10c · 10d · 10e ^
    SP1:                                                  -     -     -     -           -                 -           -                 -                           
    SP2:        -     -     -                             -     -     -     -           -                 -           -                 -                           
    SP3:                                                  -     -     -     -           -                 -           -                 -                           
    SP4:                                                  -     -     -     -           -                 -           -                 -                           
    SP5:                                                  -     -     -     -           -                 -                                                         

    ExUns: 11a · 11b · 11c ^ 12a · 12b
    SP1:              -               
    SP2:                              
    SP3:                              
    SP4:                              
    SP5:                              


    ECgene alternative splicing isoforms for HMG20B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HMG20B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCTGTACCCC
    HMG20B Expression
    About this image


    HMG20B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Heart (Cardiovascular System)
             Heart Tube
     
     Limb (Muscoskeletal System)
             Limb Bud Mesenchyme Cells Limb Bud
     
     Mesoderm (Gastrulation Derivatives)
             Limb Bud Mesenchyme Cells Limb Bud
     
     Eye (Sensory Organs)
             Retina
    HMG20B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HMG20B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.406534

    UniProtKB/Swiss-Prot: HM20B_HUMAN, Q9P0W2
    Tissue specificity: Ubiquitously expressed in adult tissues

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HMG20B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for HMG20B gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hmg20b1 , 5 high mobility group 20 B5
    high mobility group 20B1
    85.49(n)1
    93.69(a)1
      10 (39.72 cM)5
    153531  NM_001163166.11  NP_001156638.11 
     813460485 
    chicken
    (Gallus gallus)
    Aves HMG20B1 high mobility group 20B 81.96(n)
    84.25(a)
      426515  XM_004948711.1  XP_004948768.1 
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC686252 hypothetical protein MGC68625 75.25(n)    BC063718.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc85b022 Transcribed sequence with weak similarity to protein more 72(n)    57053084 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG94186
    --
    20(a)
    1 → many
    2R(17033713-17035113)
    worm
    (Caenorhabditis elegans)
    Secernentea hmg-206
    Protein HMG-20 (hmg-20) mRNA, complete cds
    16(a)
    1 → many
    I(12535322-12537671) WBGene00012209


    ENSEMBL Gene Tree for HMG20B (if available)
    TreeFam Gene Tree for HMG20B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HMG20B gene
    HMG20A2  
    9 SIMAP similar genes for HMG20B using alignment to 8 protein entries:     HM20B_HUMAN (see all proteins):
    HMG20A    SOX28    SOX25    SOX27    SMARCE1    HMGB1
    HMGB3    soxB    Bbtx1

    Find genes that share paralogs with HMG20B           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HMG20B (see all 203)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1123814701,2
    C--3336255(+) CTCAGC/TGGTCA 1 -- us2k11Minor allele frequency- T:0.50CSA 2
    rs1118284341,2
    C--3336283(+) CCCACG/ACGTCC 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs1126220891,2
    C,F--3570978(+) TCACAC/TACTGT 1 -- us2k11Minor allele frequency- T:0.50CSA 2
    rs1397523701,2
    --3571010(+) TCTCAC/GTGAGT 1 -- us2k10--------
    rs347024421,2
    C--3571091(+) TTTTT-/TGAGAC 1 -- us2k10--------
    rs1444610861,2
    C--3571361(+) ACAGGC/TGTGAG 1 -- us2k10--------
    rs1136283791,2
    C--3571374(+) ACTGCG/ACCCGG 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs1147651981,2
    C,F--3571378(+) CGCCCA/C/GGCCCA 1 -- us2k11WA 118
    rs110850231,2
    C,F,A,H--3571446(+) cagacG/Atttga 1 -- us2k117Minor allele frequency- A:0.45NS EA NA CSA WA 2088
    rs1820588901,2
    --3571564(+) GAACTA/GCTGAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for HMG20B (3572775 - 3579086 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for HMG20B (see all 14):    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv833713CNV Loss17160897
    nsv910752CNV Loss21882294
    nsv910748CNV Loss21882294
    dgv3651n71CNV Loss21882294
    dgv3657n71CNV Loss21882294
    nsv910722CNV Loss21882294
    dgv3652n71CNV Loss21882294
    nsv470114CNV Loss18288195
    dgv3656n71CNV Loss21882294
    nsv910723CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing HMG20B
    DNA2.0 Custom Variant and Variant Library Synthesis for HMG20B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 605535    OMIM disorders: --


    Find genes that share disorders with HMG20B           About GenesLikeMe


    Export disorders for HMG20B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HMG20B gene, integrated from 10 sources (see all 32):
    (articles sorted by number of sources associating them with HMG20B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. HMG20A and HMG20B map to human chromosomes 15q24 and 19p13.3 and constitute a distinct class of HMG-box genes with ubiquitous expression. (PubMed id 10773667)1, 2, 3 Sumoy L.... Peral B. (Cytogenet. Cell Genet. 2000)
    2. A human BRCA2 complex containing a structural DNA binding component influences cell cycle progression. (PubMed id 11207365)1, 2, 9 Marmorstein L.Y.... Shiekhattar R. (Cell 2001)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (Nature 2004)
    6. A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes. (PubMed id 12493763)1, 2 Hakimi M.-A.... Shiekhattar R. (J. Biol. Chem. 2003)
    7. A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes. (PubMed id 12032298)1, 2 Hakimi M.-A....Shiekhattar R. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    8. Characterization of human SMARCE1r high-mobility-group protein. (PubMed id 11997092)1, 2 Lee Y.M.... Kim W. (Biochim. Biophys. Acta 2002)
    9. Cloning a cDNA encoding an alternatively spliced protein of BRCA2- associated factor 35. (PubMed id 12083779)1, 2 Wang C.... Steiner M.S. (Biochem. Biophys. Res. Commun. 2002)
    10. Association of human kinesin superfamily protein member 4 with BRCA2-associated factor 35. (PubMed id 12809554)1, 9 Lee Y.M. and Kim W. (Biochem. J. 2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10362 HGNC: 5002 AceView: HMG20B Ensembl:ENSG00000064961 euGenes: HUgn10362
    ECgene: HMG20B H-InvDB: HMG20B

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HMG20B Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for HMG20B Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for HMG20B gene:
    Search GeneIP for patents involving HMG20B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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