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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HMG20A Gene

protein-coding   GIFtS: 50
GCID: GC15P077712

high mobility group 20A

(Previous name: high-mobility group 20A )
 Explore 4 diseases affiliated with
HMG20A via our new
 Human Malady Compendium 
Biological research products
for HMG20A
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
High Mobility Group 20A1 2     HMG Domain-Containing Protein 12 3
HMGX11 2 3     HMG Domain-Containing Protein HMGX12 3
HMGXB11 2 3     FLJ107391
High-Mobility Group 20A1 2     High Mobility Group Protein 20A2
HMG Box-Containing Protein 20A2 3     HMG Box Domain Containing 12

External Ids:    HGNC: 50011   Entrez Gene: 103632   Ensembl: ENSG000001403827   OMIM: 6055345   UniProtKB: Q9NP663   

Export aliases for HMG20A gene to outside databases

Previous GC identifers: GC15P073605 GC15P070803 GC15P075289 GC15P075429 GC15P075500 GC15P054470


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: HM20A_HUMAN, Q9NP66
Function: Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B.
Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes.
Involved in the recruitment of the histone methyltransferase MLL and consequent increased methylation of histone H3
lysine 4 (By similarity)

Gene Wiki entry for HMG20A


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NC_018926.1  NT_010194.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HMG20A gene promoter:
         HOXA9   HOXA9B   MEF-2   ATF-2   CUTL1   HNF-3beta   MEF-2A   Meis-1a   aMEF-2   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHMG20A promoter sequence
   Search SABiosciences Chromatin IP Primers for HMG20A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HMG20A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q24   Ensembl cytogenetic band:  15q24.3   HGNC cytogenetic band: 15q24

HMG20A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HMG20A gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P077712:  view genomic region     (about GC identifiers)

Start:
77,712,754 bp from pter      End:
77,777,949 bp from pter
Size:
65,196 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: HM20A_HUMAN, Q9NP66 (See protein sequence)
Recommended Name: High mobility group protein 20A  
Size: 347 amino acids; 40144 Da
Subcellular location: Nucleus (By similarity)
Secondary accessions: A6NHY3 D3DW78 Q53G31 Q9NSF6
Alternative splicing: 2 isoforms:  Q9NP66-1   Q9NP66-2   

Explore the universe of human proteins at neXtProt for HMG20A: NX_Q9NP66

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NP66

  • HMG20A Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_060670.1  
    ENSEMBL proteins: 
     ENSP00000453498   ENSP00000336856   ENSP00000371133   ENSP00000453727   ENSP00000453592  
     ENSP00000452665   ENSP00000454136   ENSP00000452864   ENSP00000452847  

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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for HMG20A

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus NAS10773667
    GO:0005730NOT nucleolus IDA--


    HMG20A for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    HMG20A for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR009071 HMG_superfamily

    Graphical View of Domain Structure for InterPro Entry Q9NP66

    ProtoNet protein and cluster: Q9NP66

    UniProtKB/Swiss-Prot: HM20A_HUMAN, Q9NP66
    Similarity: Contains 1 HMG box DNA-binding domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: HM20A_HUMAN, Q9NP66
    Function: Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B.
    Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes.
    Involved in the recruitment of the histone methyltransferase MLL and consequent increased methylation of histone H3
    lysine 4 (By similarity)

    miRNA
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    hsa-miR-607 hsa-miR-218-1* hsa-miR-200a hsa-miR-141 hsa-miR-9 hsa-miR-654-5p hsa-miR-4309 hsa-miR-761
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    Inhib. RNA
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    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding NAS10773667
    GO:0003700sequence-specific DNA binding transcription factor activity NAS10773667
    GO:0005515protein binding IPI16189514
    GO:0046982protein heterodimerization activity IEA--


    HMG20A for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HMG20A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    5/20 Interacting proteins for HMG20A (Q9NP661, 2, 3 ENSP000003368564) via UniProtKB, MINT, STRING, and/or I2D (see all 20)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TESCQ96BS21, 2, 3, ENSP000003763284EBI-740641,EBI-740653 MINT-66093 I2D: score=5 STRING: ENSP00000376328
    CCNKO759092, 3, ENSP000003745294MINT-68052 I2D: score=5 STRING: ENSP00000374529
    MAGOHBQ96A722, 3, ENSP000003192404MINT-66920 I2D: score=5 STRING: ENSP00000319240
    RBM7Q9Y5802, 3, ENSP000003646394MINT-68043 I2D: score=5 STRING: ENSP00000364639
    SMAD4Q134852, 3MINT-61963 I2D: score=3 
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IEA--
    GO:0006325chromatin organization NAS10773667
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent NAS10773667
    GO:0016568chromatin modification IEA--


    HMG20A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HMG20A
    Search CenterWatch for drugs/clinical trials and news about HMG20A / HM20A 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for HMG20A gene: 
    NM_018200.2  

    Unigene Cluster for HMG20A:

    High mobility group 20A
    Hs.744173  [show with all ESTs]
    Unigene Representative Sequence: NM_018200
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000560498 ENST00000336216(uc002bcs.3) ENST00000381714(uc002bcr.3)
    ENST00000558651 ENST00000559035 ENST00000558176 ENST00000560986(uc002bcq.1)
    ENST00000559099 ENST00000560867 ENST00000559728 ENST00000558845 ENST00000558288(uc021sra.1)


    miRNA
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    hsa-miR-607 hsa-miR-218-1* hsa-miR-200a hsa-miR-141 hsa-miR-9 hsa-miR-654-5p hsa-miR-4309 hsa-miR-761
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    Inhib. RNA
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    Additional cDNA sequence: 

    AB073664.1 AF146222.1 AK001601.1 AK025664.1 AK096546.1 AK223100.1 AK297449.1 AK311376.1 
    AK316281.1 AL355733.1 AL355737.1 AL355739.1 AL832087.1 BC021959.1 BT006716.1 

    15 DOTS entries:

    DT.100789667  DT.416983  DT.100789671  DT.91746166  DT.101981671  DT.97810013  DT.121070456  DT.97806707 
    DT.40309937  DT.121070459  DT.95075677  DT.100789670  DT.121070465  DT.100709430  DT.91800429 

    24/229 AceView cDNA sequences (see all 229):

    AK001601 CA848796 BC021959 BX355055 BQ050623 H80631 BU789676 R80124 
    CR610830 AA582488 BP376105 BU188963 BQ436616 BQ717570 AL355737 AK096546 
    BU735708 AI685985 BQ897605 BI467051 AU134157 BE221793 BQ018803 AA814525 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for HMG20A (see all 7)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9a · 9b ^ 10a · 10b
    SP1:                          -                                                     -                       -               
    SP2:                          -                                                                                             
    SP3:                          -     -                                                                                       
    SP4:                                                                                                        -               
    SP5:                    -     -                                                                                             


    ECgene alternative splicing isoforms for HMG20A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HMG20A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TGTTTGGAAC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image

    HMG20A expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    5 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Gut TubeMidgutMidgut Endoderm CellsEndoderm
    Neural TubeNeural TubeSpinal Neural Tube CellsNeural Ectoderm
    EyeRetinaEye
    Gut TubeMidgutGut Tube
    Spinal CordPresumptive Spinal CordSpinal Cord
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See HMG20A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HMG20A

    SOURCE GeneReport for Unigene cluster: Hs.744173

    UniProtKB/Swiss-Prot: HM20A_HUMAN, Q9NP66
    Tissue specificity: Ubiquitous

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HMG20A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for HMG20A gene from 6/24 species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves HMG20A1 high mobility group 20A 78(n)
    83.86(a)
      415346  NM_001030394.1  NP_001025565.1 
    lizard
    (Anolis carolinensis)
    Reptilia HMG20A6
    --
    83(a)
    1 ↔ 1
    GL343374.1(829354-840360)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.78602 Xenopus laevis transcribed sequence with weak similarity more 76.72(n)    BJ073811.1 
    zebrafish
    (Danio rerio)
    Actinopterygii hmg20a1 high-mobility group 20A 69.11(n)
    74.13(a)
      326908  NM_001089334.1  NP_001082803.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG94181 CG9418 44.92(n)
    32.78(a)
      37407  NM_137709.3  NP_611553.1 
    worm
    (Caenorhabditis elegans)
    Secernentea hmg-206
    Protein HMG-20
    20(a)
    possible ortholog
    I(12535312-12537661)


    ENSEMBL Gene Tree for HMG20A (if available)
    TreeFam Gene Tree for HMG20A (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HMG20A gene
    HMG20B2  SSRP12  
    1 SIMAP similar gene for HMG20A using alignment to 8 protein entries:     HM20A_HUMAN (see all proteins):
    HMG20B

    HMG20A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/34 NCBI SNPs in HMG20A are shown (see all 34    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs750925781,2
    --54468393(+) TCATAG/CTTTTC 1 -- us2k11Minor allele frequency- C:0.01WA 118
    rs765334511,2
    F,--54468678(+) AGGAGG/AAAAGA 1 -- us2k11Minor allele frequency- A:0.02NA 120
    rs759335441,2
    C,F,--54470816(+) NNNNCG/AACATA 1 -- int11Minor allele frequency- A:0.03NA 120
    rs740252021,2
    C,--54471149(+) TTCTTC/ATGTGT 1 -- int11Minor allele frequency- A:0.50WA 2
    rs1441175991,2
    --77711282(+) AATGAC/TCTAAA 1 -- int10--------
    rs125935821,2
    C,F,H,--77711366(+) AAAATG/CAATTA 1 -- int115Minor allele frequency- C:0.12NS EA NA WA CSA 675
    rs1876467121,2
    --77711614(+) GAAATC/TAAGCT 1 -- int10--------
    rs1459861651,2
    --77711644(+) CGACGA/GGAGGG 1 -- int10--------
    rs1399723731,2
    --77711650(+) GAGGGA/GAGGGG 1 -- int10--------
    rs620072991,2
    C,F,--77711719(+) GGATGA/GGTCAA 1 -- int19Minor allele frequency- G:0.48NA WA CSA EA 369

    HapMap Linkage Disequilibrium report for HMG20A (77712754 - 77777949 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for HMG20A: --

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    HMG20A for disorders           About GeneDecksing

    OMIM gene information: 605534    OMIM disorders: --

    4 diseases for HMG20A:    About MalaCards
    cerebellar ataxia    cowpox    ataxia    neuronitis

    1 disease from the University of Copenhagen DISEASES database for HMG20A:
    Cowpox

    Export disorders for HMG20A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HMG20A gene, integrated from 9 sources (see all 23):
    (articles sorted by number of sources associating them with HMG20A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. HMG20A and HMG20B map to human chromosomes 15q24 and 19p13.3 and constitute a distinct class of HMG-box genes with ubiquitous expression. (PubMed id 10773667)1, 2, 3 Sumoy L.... Peral B. (2000)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Stratifying type 2 diabetes cases by BMI identifies ge netic risk variants in LAMA1 and enrichment for risk variants in lean compared t o obese cases. (PubMed id 22693455)1 Perry J.R....Cauchi S. (2012)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    6. Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. (PubMed id 21874001)1 Kooner J.S....Chambers J.C. (2011)
    7. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    8. Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia. (PubMed id 21490949)1 Sim X....Tai E.S. (2011)
    9. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    10. The interaction with HMG20a/b proteins suggests a pot ential role for beta-dystrobrevin in neuronal differentiation. (PubMed id 20530487)1 Artegiani B....Macioce P. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10363 HGNC: 5001 AceView: HMG20A Ensembl:ENSG00000140382 euGenes: HUgn10363
    ECgene: HMG20A H-InvDB: HMG20A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HMG20A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for HMG20A gene:
    Search GeneIP for patents involving HMG20A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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