Aliases for HLX Gene
Aliases for HLX Gene
External Ids for HLX Gene
- HGNC: 4978
- Entrez Gene: 3142
- Ensembl: ENSG00000136630
- OMIM: 142995
- UniProtKB: Q14774
Previous HGNC Symbols for HLX Gene
- HLX1
Previous GeneCards Identifiers for HLX Gene
- GC01P219120
- GC01P221052
- GC01P191727
Summaries for HLX Gene
GeneCards Summary for HLX Gene
HLX (H2.0 Like Homeobox) is a Protein Coding gene. Diseases associated with HLX include Ovarian Primitive Germ Cell Tumor and Ovarian Endodermal Sinus Tumor. Among its related pathways are IL12-mediated signaling events. GO annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is DBX1.
UniProtKB/Swiss-Prot for HLX Gene
-
Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis (By similarity).
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HLX Gene
Genomics for HLX Gene
Regulatory Elements for HLX Gene
Enhancers for HLX Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH01G220875 | 1.6 | FANTOM5 ENCODE dbSUPER | 31.4 | +0.9 | 887 | 9.7 | YY1 GLIS2 GATA2 FOS SP3 JUNB CBX8 SMARCA4 NBN HNF4A | HLX ENSG00000272823 HLX-AS1 LINC01352 RNU6ATAC35P GC01P220882 |
| GH01G220954 | 1.4 | FANTOM5 Ensembl ENCODE | 29.9 | +77.4 | 77362 | 3.7 | BACH1 CEBPG FOSL1 ZNF316 EGR1 FOS NFE2 TRIM24 MAFK NFE2L2 | HLX LINC01352 GC01P220953 LOC105372930 |
| GH01G220961 | 1.4 | FANTOM5 Ensembl ENCODE | 29.6 | +82.8 | 82844 | 1.9 | PKNOX1 FOXA2 TAL1 MAX RAD21 YY1 ZNF316 HNF4G FOS CREM | HLX GC01P220953 LOC105372930 |
| GH01G221097 | 1.6 | FANTOM5 Ensembl ENCODE | 24.7 | +220.1 | 220100 | 4.7 | HDAC1 PKNOX1 FEZF1 RAD21 YY1 TCF12 GATA2 FOS JUNB CEBPB | HLX HLX-AS1 GC01M220652 GC01P221076 |
| GH01G221000 | 1.1 | FANTOM5 Ensembl ENCODE | 28.6 | +121.2 | 121201 | 1.2 | MAX MNT RAD21 | HLX ENSG00000272823 GC01P221007 GC01P220990 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around HLX on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the HLX gene promoter:
Regulatory Element Products
Genomic Location for HLX Gene
- Chromosome:
- 1
- Start:
- 220,879,400 bp from pter
- End:
- 220,885,059 bp from pter
- Size:
- 5,660 bases
- Orientation:
- Plus strand
Genomic View for HLX Gene
Genes around HLX on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1q41 by Ensembl
- 1q41 by Entrez Gene
- 1q41 by HGNC
HLX Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HLX Gene
Proteins for HLX Gene
-
Protein details for HLX Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q14774-HLX_HUMAN
- Recommended name:
- H2.0-like homeobox protein
- Protein Accession:
- Q14774
- B2R8A8
- Q15988
- Q59HE7
- Q9NZ75
Protein attributes for HLX Gene
- Size:
- 488 amino acids
- Molecular mass:
- 50789 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAD92049.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAD92049.1; Type=Frameshift; Positions=198, 259, 321; Evidence={ECO:0000305}; Sequence=M60721; Type=Frameshift; Positions=69, 115, 152, 167; Evidence={ECO:0000305};
Protein Expression for HLX Gene
Post-translational modifications for HLX Gene
Other Protein References for HLX Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for HLX
- Novus Biologicals Antibodies for HLX
- Invitrogen Antibodies for HLX
- antibodies-online Antibodies for HLX: See all 56
- GeneTex HLX antibody for HLX
-
Santa Cruz Biotechnology (SCBT) Antibodies for HLX
Protein Products
-
OriGene Purified Proteins for HLX
- Search Origene for MassSpec and Protein Over-expression Lysates for HLX
- Origene Custom Protein Services for HLX
- antibodies-online Proteins for HLX: See all 6
- Search antibodies-online for peptides
- Search GeneTex for Proteins for HLX
Assay Products
No data available for DME Specific Peptides for HLX Gene
Domains & Families for HLX Gene
Gene Families for HLX Gene
Protein Domains for HLX Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for HLX Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q14774- Family:
-
- Belongs to the H2.0 homeobox family.
Function for HLX Gene
Molecular function for HLX Gene
- UniProtKB/Swiss-Prot Function:
- Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis (By similarity).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | -- |
| GO:0005515 | protein binding | IPI | 23455154 |
| GO:0043565 | sequence-specific DNA binding | IEA,IDA | 9073066 |
Phenotypes for HLX Gene
- MGI mutant phenotypes for HLX:
-
inferred from 1 alleles
- mortality/aging
- growth/size/body region phenotype
- muscle phenotype
- nervous system phenotype
- homeostasis/metabolism phenotype
- respiratory system phenotype
- digestive/alimentary phenotype
- endocrine/exocrine gland phenotype
- integument phenotype
- hematopoietic system phenotype
- liver/biliary system phenotype
- GenomeRNAi human phenotypes for HLX:
Animal Models for HLX Gene
- MGI Knock Outs for HLX:
-
- Hlx tm1Rph
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for HLX gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HLX gene
- Search ViGene Biosciences for HLX
CRISPR Products
-
OriGene CRISPR knockouts for HLX
-
Santa Cruz Biotechnology (SCBT) CRISPR for HLX
- GenScript: Design CRISPR guide RNA sequences for HLX
miRNA for HLX Gene
- miRTarBase miRNAs that target HLX
-
- hsa-mir-1260b (MIRT052679)
- hsa-mir-5572 (MIRT717631)
- hsa-mir-4260 (MIRT717632)
- hsa-mir-450a-2-3p (MIRT717633)
- hsa-mir-6857-5p (MIRT717634)
- hsa-mir-6763-5p (MIRT717635)
- hsa-mir-3150a-3p (MIRT717636)
- hsa-mir-6810-5p (MIRT717637)
- hsa-mir-2110 (MIRT717638)
- hsa-mir-4423-3p (MIRT717639)
- hsa-mir-6825-5p (MIRT717640)
- hsa-mir-939-5p (MIRT717641)
- hsa-mir-1343-5p (MIRT717642)
- hsa-mir-3175 (MIRT717643)
- hsa-mir-6878-5p (MIRT717644)
- hsa-mir-3670 (MIRT717645)
- hsa-mir-645 (MIRT717646)
- hsa-mir-3622a-5p (MIRT717647)
- hsa-mir-5582-5p (MIRT717648)
- hsa-mir-1276 (MIRT717649)
miRNA Products
- Search ViGene Biosciences for HLX
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HLX
- Browse OriGene Inhibitory RNA Products For HLX
-
ViGene Biosciences ready-to-package AAV shRNAs for HLX gene
Cell Line Products
-
Horizon Cell Lines for HLX
-
ViGene Biosciences adenoviral particle packaged cDNA for HLX gene
-
ViGene Biosciences lentiviral particle packaged cDNA for HLX gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HLX gene
Flow Cytometry Products
- eBioscience FlowRNA Probe Sets (VA1-12787) for HLX
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for HLX Gene
Localization for HLX Gene
Subcellular locations from UniProtKB/Swiss-Prot for HLX Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 2 |
| extracellular | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
Pathways & Interactions for HLX Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | IL12-mediated signaling events | ||
Pathways by source for HLX Gene
1 BioSystems pathway for HLX Gene
Interacting Proteins for HLX Gene
Selected Interacting proteins:
ENSP00000355870
Q14774-HLX_HUMAN
for HLX Gene via
STRING
UniProtKB
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001889 | liver development | IEA | -- |
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0007275 | multicellular organism development | TAS | 8094082 |
| GO:0007519 | skeletal muscle tissue development | IEA | -- |
No data available for SIGNOR curated interactions for HLX Gene
Transcripts for HLX Gene
mRNA/cDNA for HLX Gene
- (1) REFSEQ mRNAs :
- (6) Additional mRNA sequences :
- (66) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for HLX
-
Santa Cruz Biotechnology (SCBT) CRISPR for HLX
- GenScript: Design CRISPR guide RNA sequences for HLX
miRNA Products
- Search ViGene Biosciences for HLX
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HLX
- Browse OriGene Inhibitory RNA Products For HLX
-
ViGene Biosciences ready-to-package AAV shRNAs for HLX gene
Flow Cytometry Products
- eBioscience FlowRNA Probe Sets (VA1-12787) for HLX
Expression for HLX Gene
mRNA differential expression in normal tissues according to GTEx for HLX Gene
This gene is overexpressed in Whole Blood (x8.1) and Colon - Sigmoid (x4.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for HLX Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of HLX Gene:
HLXSOURCE GeneReport for Unigene cluster for HLX Gene:
Hs.74870mRNA Expression by UniProt/SwissProt for HLX Gene:
Q14774-HLX_HUMAN
Tissue specificity:
Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain.
Evidence on tissue expression from TISSUES for HLX Gene
- Nervous system(4.3)
- Intestine(4.2)
- Eye(4)
- Bone marrow(2)
Primer Products
-
OriGene qPCR primer pairs for HLX
-
OriGene qPCR primer pairs and template standards for HLX
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for HLX Gene
Orthologs for HLX Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | HLX 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | HLX 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | HLX 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Hlx 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Hlx 34 16 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | HLX 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | HLX 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | HLX 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | HLX 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | hlx 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | hlx1 34 35 |
|
||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.2656 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | H2.0 35 |
|
OneToOne | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToOne |
- Species where no ortholog for HLX was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for HLX Gene
(29) SIMAP similar genes for HLX Gene using alignment to 3 proteins:
Variants for HLX Gene
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000296405 | -- | 220,884,582(+) | CCAGT(A/G)CGGGT | reference, missense | |
| rs1000544653 | -- | 220,878,827(+) | GGAGG(A/G)TCTCC | intron-variant, upstream-variant-2KB | |
| rs1001151255 | -- | 220,879,804(+) | GCGCG(C/T)CCACC | intron-variant, utr-variant-5-prime | |
| rs1001419455 | -- | 220,881,125(+) | AGGGG(A/G)GGAAC | intron-variant, upstream-variant-2KB | |
| rs1001812349 | -- | 220,884,922(+) | CGAAC(A/G)CTTCT | utr-variant-3-prime |
Residual Variation Intolerance Score:
55.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
12.70;
94.63% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for HLX Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HLX Gene
Disorders for HLX Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| ovarian primitive germ cell tumor |
|
|
| ovarian endodermal sinus tumor |
|
|
| endodermal sinus tumor |
|
|
| holoprosencephaly-3 |
|
|
| usher syndrome, type 2a |
|
|
Search HLX in MalaCards
View complete list of genes associated with diseases
Relevant External Links for HLX
No data available for UniProtKB/Swiss-Prot and Genatlas for HLX Gene
Publications for HLX Gene
- Cloning of a human homeobox gene that resembles a diverged Drosophila homeobox gene and is expressed in activated lymphocytes. (PMID: 1676597) Deguchi Y. … Kehrl J.H. (New Biol. 1991) 2 3 4 22 64
- Genomic structure, promoter sequence, and revised translation of human homeobox gene HLX1. (PMID: 7806220) Kennedy M.A. … Morris C.M. (Genomics 1994) 2 3 4 64
- Linkage localization of TGFB2 and the human homeobox gene HLX1 to chromosome 1q. (PMID: 8095486) Nishimura D.Y. … Murray J.C. (Genomics 1993) 3 4 22 64
- TBX21 gene variants increase childhood asthma risk in combination with HLX1 variants. (PMID: 19362357) Suttner K. … Kabesch M. (J. Allergy Clin. Immunol. 2009) 3 46 64
- HLX1 gene variants influence the development of childhood asthma. (PMID: 19038437) Suttner K. … Kabesch M. (J. Allergy Clin. Immunol. 2009) 3 46 64
Products for HLX Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for HLX
- Search Origene for MassSpec and Protein Over-expression Lysates for HLX
- Origene Custom Protein Services for HLX
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for HLX
- Browse OriGene Inhibitory RNA Products For HLX
- OriGene qPCR primer pairs and template standards for HLX
- OriGene qPCR primer pairs for HLX
- OriGene CRISPR knockouts for HLX
- OriGene ORF clones in human for HLX
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For HLX
- GenScript: Next-day shipping cDNA ORF clone for HLX in any vector
- GenScript Custom Purified and Recombinant Proteins Services for HLX
- GenScript Custom Assay Services for HLX
- GenScript Custom overexpressing Cell Line Services for HLX
- GenScript: Design CRISPR guide RNA sequences for HLX
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for HLX
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for HLX
- Novus Biologicals proteins and lysates for HLX
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- antibodies-online Antibodies for HLX: See all 56
- Search antibodies-online for kits
- antibodies-online Proteins for HLX: See all 6
- Search antibodies-online for peptides
- GeneTex HLX antibody for HLX
- Search GeneTex for Proteins for HLX
- ViGene Biosciences adenoviral particle packaged cDNA for HLX gene
- ViGene Biosciences lentiviral particle packaged cDNA for HLX gene
- ViGene Biosciences ready-to-package AAV shRNAs for HLX gene
- Search ViGene Biosciences for HLX
- Santa Cruz Biotechnology (SCBT) Antibodies for HLX
- Search Santa Cruz Biotechnology (SCBT) for HLX siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for HLX
- Horizon Cell Lines for HLX
- Cyagen custom Knockout/knockin (KOKI) mouse models for HLX
- VectorBuilder custom plasmid, inducible vectors for HLX
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HLX
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for HLX Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer