Free for academic non-profit institutions. Other users need a Commercial license

Aliases for HLA-L Gene

Aliases for HLA-L Gene

  • Major Histocompatibility Complex, Class I, L (Pseudogene) 2 3 5
  • HLA-92 3
  • HLA92 3
  • HLAL 3

External Ids for HLA-L Gene

Previous HGNC Symbols for HLA-L Gene

  • HLA92
  • HLAL

Previous GeneCards Identifiers for HLA-L Gene

  • GC06U990059
  • GC06P030332
  • GC06P030334
  • GC06P030226
  • GC06P030370
  • GC06P030316
  • GC06P030417
  • GC06P030432
  • GC06P030520

Summaries for HLA-L Gene

GeneCards Summary for HLA-L Gene

HLA-L (Major Histocompatibility Complex, Class I, L (Pseudogene)) is a Pseudogene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HLA-L Gene

Genomics for HLA-L Gene

Regulatory Elements for HLA-L Gene

Enhancers for HLA-L Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06F030258 1 ENCODE 22.6 +0.1 96 1.7 ATF1 ARID4B SIN3A DMAP1 ZNF48 ZNF2 ZNF143 FOS ZNF202 ZNF263 HCG18 DHX16 PPP1R10 HLA-U ETF1P1 HLA-L PAIP1P1 HCG4P7 HLA-H GTF2H4
GH06F030776 1.9 FANTOM5 Ensembl ENCODE 11.2 +523.7 523739 13.8 MLX CREB3L1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 IER3 PPP1R10 PAIP1P1 DHX16 LY6G5B GTF2H4 ABCF1 DDX39B VARS2 HCG18
GH06F030321 0.9 ENCODE 21.2 +63.2 63240 2.3 PKNOX1 PTRF SCRT2 KLF13 ZNF362 ZBTB2 CEBPB HDAC8 ZNF592 CREB3 HCG18 HLA-L HLA-U RPL23AP1 IFITM4P PPP1R10 PRR3 GTF2H4 RPP21 HLA-F-AS1
GH06F030816 1.8 FANTOM5 Ensembl ENCODE 8.3 +560.4 560439 6.8 HDGF PKNOX1 ARNT MLX ARID4B SLC30A9 ZNF143 FOS KLF13 SP5 IER3 DDR1 HCG18 PRR3 RPP21 PPP1R10 HLA-E PPP1R18 FLOT1 LINC00243
GH06F030645 1.2 ENCODE 10.3 +387.7 387730 2.6 HDGF PKNOX1 ARNT MLX ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 RPL7P4 ABCF1 TMPOP1 UBQLN1P1 SNORA38 HLA-P ENSG00000233902 DHX16 DDX39B HCG18
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around HLA-L on UCSC Golden Path with GeneCards custom track

Promoters for HLA-L Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000129694 339 1800 ATF1 ARID4B SIN3A DMAP1 ZNF48 ZNF2 ZNF143 FOS ZNF202 ZNF263

Genomic Location for HLA-L Gene

Chromosome:
6
Start:
30,259,562 bp from pter
End:
30,293,014 bp from pter
Size:
33,453 bases
Orientation:
Plus strand

Genomic View for HLA-L Gene

Genes around HLA-L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HLA-L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HLA-L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for HLA-L Gene

Post-translational modifications for HLA-L Gene

No Post-translational modifications

No data available for DME Specific Peptides for HLA-L Gene

Domains & Families for HLA-L Gene

Gene Families for HLA-L Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with HLA-L: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HLA-L Gene

Function for HLA-L Gene

Molecular function for HLA-L Gene

GENATLAS Biochemistry:
HLA class I-like gene L,9.2 Hind III fragment,see MHC1
genes like me logo Genes that share phenotypes with HLA-L: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HLA-L Gene

Localization for HLA-L Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for HLA-L Gene

Pathways & Interactions for HLA-L Gene

SuperPathways for HLA-L Gene

No Data Available

Interacting Proteins for HLA-L Gene

Gene Ontology (GO) - Biological Process for HLA-L Gene

None

No data available for Pathways by source and SIGNOR curated interactions for HLA-L Gene

Transcripts for HLA-L Gene

mRNA/cDNA for HLA-L Gene

(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for HLA-L Gene

No ASD Table

Relevant External Links for HLA-L Gene

GeneLoc Exon Structure for
HLA-L
ECgene alternative splicing isoforms for
HLA-L

Expression for HLA-L Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for HLA-L Gene

genes like me logo Genes that share expression patterns with HLA-L: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for HLA-L Gene

Orthologs for HLA-L Gene

Evolution for HLA-L Gene

ENSEMBL:
Gene Tree for HLA-L (if available)
TreeFam:
Gene Tree for HLA-L (if available)

No data available for Orthologs for HLA-L Gene

Paralogs for HLA-L Gene

No data available for Paralogs for HLA-L Gene

Variants for HLA-L Gene

Sequence variations from dbSNP and Humsavar for HLA-L Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs111358359 -- 30,261,257(+) CACCC(-/T)TGAGG intron-variant, nc-transcript-variant
rs111443459 -- 30,264,612(+) GCAGG(C/T)GGGAA intron-variant, nc-transcript-variant
rs111980440 -- 30,259,897(+) TACGT(A/G)GACGA intron-variant
rs112198104 -- 30,262,353(+) ACATG(C/G)GGGGG intron-variant
rs112503252 -- 30,259,549(+) CGCCG(-/CGATCCCGGCACTA)CGATC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for HLA-L Gene

Variant ID Type Subtype PubMed ID
nsv601264 CNV loss 21841781
nsv1144137 CNV deletion 24896259
nsv1122126 CNV deletion 24896259
nsv1074389 CNV deletion 25765185
esv3411275 CNV duplication 20981092
esv2731786 CNV deletion 23290073
esv2731785 CNV deletion 23290073
esv2731783 CNV deletion 23290073
esv2731782 CNV deletion 23290073
esv2731777 CNV deletion 23290073

Relevant External Links for HLA-L Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HLA-L

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HLA-L Gene

Disorders for HLA-L Gene

Relevant External Links for HLA-L

Genetic Association Database (GAD)
HLA-L
Human Genome Epidemiology (HuGE) Navigator
HLA-L
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HLA-L

No disorders were found for HLA-L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HLA-L Gene

Publications for HLA-L Gene

  1. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PMID: 19851445) Barcellos L.F. … Criswell L.A. (PLoS Genet. 2009) 3 46 64
  2. Examination of four HLA class I pseudogenes. Common events in the evolution of HLA genes and pseudogenes. (PMID: 1517564) Geraghty D.E. … Hansen J.A. (J. Immunol. 1992) 2 3 64
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
  5. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3 64

Products for HLA-L Gene

Sources for HLA-L Gene

Content
Loading form....