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Aliases for HLA-J Gene

Aliases for HLA-J Gene

  • Major Histocompatibility Complex, Class I, J (Pseudogene) 2 3 5
  • HLA-CDA12 3
  • HLA-59 3
  • D6S203 3
  • CDA12 3

External Ids for HLA-J Gene

Previous HGNC Symbols for HLA-J Gene

  • HLA-CDA12
  • D6S203

Previous GeneCards Identifiers for HLA-J Gene

  • GC06U990057
  • GC06M030029
  • GC06P029857
  • GC06P029905
  • GC06P030018
  • GC06P029908
  • GC06P029909
  • GC06P029910
  • GC06P030082
  • GC06P030073
  • GC06P029979
  • GC06P029984
  • GC06P029989
  • GC06P029998
  • GC06P030190
  • GC06P030222
  • GC06P030260
  • GC06P030359
  • GC06P030507

Summaries for HLA-J Gene

Entrez Gene Summary for HLA-J Gene

  • This major histocompatibility complex gene represents a transcribed pseudogene, possibly derived from HLA-A. [provided by RefSeq, May 2010]

GeneCards Summary for HLA-J Gene

HLA-J (Major Histocompatibility Complex, Class I, J (Pseudogene)) is a Pseudogene. Among its related pathways are Regulation of activated PAK-2p34 by proteasome mediated degradation.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HLA-J Gene

Genomics for HLA-J Gene

Regulatory Elements for HLA-J Gene

Enhancers for HLA-J Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06F029940 1 ENCODE 94.1 -63.7 -63711 3.7 HDGF PKNOX1 ATF1 WRNIP1 ZFP64 ARID4B DMAP1 ZNF2 YY1 GLIS2 HLA-J HLA-T HLA-G HLA-H HLA-W HLA-K HLA-A HCG4P3 ZFP57 HLA-U
GH06F029952 0.8 Ensembl ENCODE 93.8 -52.7 -52677 1.3 ZNF146 JUND ATF3 NR2F1 JUN ADNP NR2F6 HLA-J HLA-T HLA-K HLA-A HCG4P5 ZFP57 MICD HCG4P3 HCG4P4 PIR61557
GH06F029722 1 ENCODE 43.3 -281.4 -281389 4.1 ATF1 WRNIP1 SIN3A GLIS2 CBX5 ZNF143 ZNF207 FOS ZNF263 NFYC HLA-F HLA-J ZFP57 HLA-H HCG4P5 IFITM4P HLA-F-AS1 DHX16 MICE HCG4P7
GH06F029963 1.8 FANTOM5 Ensembl ENCODE 22.4 -39.7 -39722 4.8 HDGF PKNOX1 ARNT CREB3L1 MLX WRNIP1 ZFP64 ARID4B SIN3A FEZF1 HLA-A HLA-W HLA-K MICD HLA-H HLA-J HCG4P5 HCG4 IFITM4P ABCF1
GH06F029947 0.5 ENCODE 78.2 -58.5 -58453 0.2 PAF1 POLR2A ZBED1 HLA-J HLA-T HLA-A HLA-H PIR61557 HCG4P4
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around HLA-J on UCSC Golden Path with GeneCards custom track

Promoters for HLA-J Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000487585 630 1200 GATAD2A ZNF366 SUZ12 GABPB1 IKZF1 REST ZNF48 EZH2

Genomic Location for HLA-J Gene

Chromosome:
6
Start:
30,005,971 bp from pter
End:
30,009,956 bp from pter
Size:
3,986 bases
Orientation:
Plus strand

Genomic View for HLA-J Gene

Genes around HLA-J on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HLA-J Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HLA-J Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for HLA-J Gene

Post-translational modifications for HLA-J Gene

No Post-translational modifications

No data available for DME Specific Peptides for HLA-J Gene

Domains & Families for HLA-J Gene

Gene Families for HLA-J Gene

Suggested Antigen Peptide Sequences for HLA-J Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with HLA-J: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for HLA-J Gene

Function for HLA-J Gene

Molecular function for HLA-J Gene

GENATLAS Biochemistry:
HLA class I-like gene J,5.9 Hind III fragment,see MHC1

Phenotypes for HLA-J Gene

GenomeRNAi human phenotypes for HLA-J:
genes like me logo Genes that share phenotypes with HLA-J: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HLA-J Gene

Localization for HLA-J Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for HLA-J Gene

Pathways & Interactions for HLA-J Gene

genes like me logo Genes that share pathways with HLA-J: view

Pathways by source for HLA-J Gene

1 BioSystems pathway for HLA-J Gene

Interacting Proteins for HLA-J Gene

Gene Ontology (GO) - Biological Process for HLA-J Gene

None

No data available for SIGNOR curated interactions for HLA-J Gene

Transcripts for HLA-J Gene

mRNA/cDNA for HLA-J Gene

(4) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HLA-J Gene

Major histocompatibility complex, class I, J (pseudogene):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for HLA-J Gene

No ASD Table

Relevant External Links for HLA-J Gene

GeneLoc Exon Structure for
HLA-J
ECgene alternative splicing isoforms for
HLA-J

Expression for HLA-J Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for HLA-J Gene

mRNA differential expression in normal tissues according to GTEx for HLA-J Gene

This gene is overexpressed in Whole Blood (x7.3).

Protein differential expression in normal tissues from HIPED for HLA-J Gene

This gene is overexpressed in Skin (68.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from MOPED for HLA-J Gene



Protein tissue co-expression partners for HLA-J Gene

- Elite partner

SOURCE GeneReport for Unigene cluster for HLA-J Gene:

Hs.720762
genes like me logo Genes that share expression patterns with HLA-J: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for HLA-J Gene

Orthologs for HLA-J Gene

Evolution for HLA-J Gene

ENSEMBL:
Gene Tree for HLA-J (if available)
TreeFam:
Gene Tree for HLA-J (if available)

No data available for Orthologs for HLA-J Gene

Paralogs for HLA-J Gene

genes like me logo Genes that share paralogs with HLA-J: view

No data available for Paralogs for HLA-J Gene

Variants for HLA-J Gene

Sequence variations from dbSNP and Humsavar for HLA-J Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs111824635 -- 30,009,631(+) AAGGC(A/G/T)TCTGA intron-variant, nc-transcript-variant, upstream-variant-2KB
rs112112975 -- 30,004,306(+) TCCCT(A/G)TTCTC intron-variant, upstream-variant-2KB
rs112389814 -- 30,007,003(+) CCAAG(C/G)CCCAG intron-variant, nc-transcript-variant, downstream-variant-500B
rs112706192 -- 30,007,317(+) GGCCA(C/G)GGTAT intron-variant, nc-transcript-variant
rs113017032 -- 30,009,565(+) CTGAG(A/T)GGCAA intron-variant, nc-transcript-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for HLA-J Gene

Variant ID Type Subtype PubMed ID
nsv981126 CNV duplication 23825009
nsv601475 CNV loss 21841781
nsv601264 CNV loss 21841781
nsv508398 CNV deletion 20534489
nsv1144137 CNV deletion 24896259
nsv1122126 CNV deletion 24896259
nsv1074389 CNV deletion 25765185
esv3570888 CNV loss 25503493
esv3411275 CNV duplication 20981092
esv2759412 CNV gain+loss 17122850
esv2731778 CNV deletion 23290073
esv2731777 CNV deletion 23290073
esv2641340 CNV deletion 19546169
dgv993e201 CNV deletion 23290073
dgv1088e199 CNV deletion 23128226

Relevant External Links for HLA-J Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HLA-J

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HLA-J Gene

Disorders for HLA-J Gene

Relevant External Links for HLA-J

Genetic Association Database (GAD)
HLA-J
Human Genome Epidemiology (HuGE) Navigator
HLA-J
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HLA-J

No disorders were found for HLA-J Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HLA-J Gene

Publications for HLA-J Gene

  1. A major histocompatibility Class I locus contributes to multiple sclerosis susceptibility independently from HLA-DRB1*15:01. (PMID: 20593013) Cree B.A. … . (PLoS ONE 2010) 3 46 64
  2. HLA-J, a second inactivated class I HLA gene related to HLA-G and HLA-A. Implications for the evolution of the HLA-A-related genes. (PMID: 1602142) Messer G. … Girdlestone J. (J. Immunol. 1992) 2 3 64
  3. Paradoxical downregulation of HLA-A expression by IFNI^ associated with schizophrenia and noncoding genes. (PMID: 23083632) Gu S. … Wank R. (Immunobiology 2013) 3 64
  4. Identification of independent risk loci for Graves' disease within the MHC in the Japanese population. (PMID: 21900946) Nakabayashi K. … Shirasawa S. (J. Hum. Genet. 2011) 3 64
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64

Products for HLA-J Gene

Sources for HLA-J Gene

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